[Current events in fetal magnetic resonance]. / Actualité sur l'imagerie par résonance magnétique (IRM) foetale.

The challenge of fetal imaging is crucial in France because of the law allowing termination of pregnancy (TOP) until the end of pregnancy. Fetal MRI is an imaging tool always used after ultrasonography (US). Its indications are pertinent only in relation with a prenatal center. Fetal MRI raises parental anxiety to take into account before and during the examination. To date, cerebral indications are predominant. Fetal brain maturation can be followed with MRI (gyration and myelination) but the optimal moment of a fetal MRI depends on the suspected pathology: the analysis of gyration is possible only by 28 WG, as before this time, the brain surface is smooth; in contrast, the posterior fossa demonstrates a definitive morphology since 20 WG. The ventriculomegaly is the most frequent call sign and includes various entities. MRI can disclose associated abnormalities (heterotopia, gyration, white matter, median line), which can suggest diagnosis and pronosis. A cystic pouch of the posterior fossa must lead to a careful analysis of cerebellum and brainstem to approach the diagnosis. Extracerebral indications become progressively larger and fetal MRI is a useful complementary tool after US to study tumors, particularly cervicothoracic masses. MRI can help to assess the level of bowel obstruction but multiple stenosis and post-stenotic bowel is difficult to evaluate. Fetal MRI can help to evaluate bilateral important pyelocalicial dilatation.

[Venous infarction of the neonate]. / L'infarctus veineux hémorragique du nouveau-né

PURPOSE: To determine the imaging features of hemorrhagic infarction in neonates. PATIENTS AND METHODS: Retrospective study (1998-2008) of 19 children (17 premature and 2 term deliveries) with early lobar hyperechogenicity on transfontanel US (TFUS). Group I: 11 born infants with clinical as well as TFUS and MRI follow-up. Group II: 8 premature infants deceased within a week from multisystem pathology, with neuropathological study available in 3 cases. RESULTS: Group I (n=11): periventricular hyperechogenicity in a frontal (7), frontoparietal (2), parietooccipital (1) and temporoparietal (1) distribution with developing cavitary change (n=6). MRI showed a cortex sparing intraparenchymal hematoma. Group II (n=8): periventricular hyperechogenicity in a frontal (4), frontoparietal or parietal (3) and occipital (1) with developing cavitary change (3). Neuropathological examination showed characteristic lesions of venous hemorrhagic infarction. Clinical outcome was generally favorable for the surviving infants with contralateral motor deficit (n=5) non-correlated to the extent of the initial lesions. CONCLUSION: Venous hemorrhagic infarction mainly affetcs premature infants and typically involves the periventricular frontal white matter. Prognosis is generally favorable. It is thus important to differentiate this entity from asymmetrical cystic periventricular leukomalacia with much different prognosis.

Fetal hemangiopericytoma with an associated cerebral anomaly.

We report the first case of infantile hemangiopericytoma explored prenatally by fetal ultrasonography and magnetic resonance imaging (MRI). It was associated with a developmental cerebral anomaly identified on MRI. The largest lesions of the multifocal hemangiopericytoma were located in the soft tissue adjacent to the left temporal bone, and smaller lesions were found in the lumbar area and in the retroperitoneum. MRI showed no connection between the tumor and the fetal brain but there was anomalous cerebral gyration in the region and the Sylvian fissure beneath the tumor was enlarged. The pregnancy was terminated because of the severe brain anomalies and postmortem examination confirmed the prenatal findings. Microscopic analysis of the tumor tissue showed branching vessels which are typical of hemangiopericytoma. The lesions in our case occurred in association with macrosomia with visceromegaly detected at autopsy, suggesting a possible role of tumor suppressor genes.

Preconception seroconversion and maternal seronegativity at delivery do not rule out the risk of congenital toxoplasmosis.

We describe two unusual cases of congenital toxoplasmosis, one occurring after preconception maternal infection with cervical adenopathies and the other occurring after maternal infection at the very end of pregnancy with maternal seronegativity at delivery. These documented cases of congenital toxoplasmosis demonstrate the value of extending the serologic monitoring period during pregnancy, according to the individual clinical context.