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1.
Sci Rep ; 14(1): 6100, 2024 03 13.
Artigo em Inglês | MEDLINE | ID: mdl-38480815

RESUMO

Endoscopy, a widely used medical procedure for examining the gastrointestinal (GI) tract to detect potential disorders, poses challenges in manual diagnosis due to non-specific symptoms and difficulties in accessing affected areas. While supervised machine learning models have proven effective in assisting clinical diagnosis of GI disorders, the scarcity of image-label pairs created by medical experts limits their availability. To address these limitations, we propose a curriculum self-supervised learning framework inspired by human curriculum learning. Our approach leverages the HyperKvasir dataset, which comprises 100k unlabeled GI images for pre-training and 10k labeled GI images for fine-tuning. By adopting our proposed method, we achieved an impressive top-1 accuracy of 88.92% and an F1 score of 73.39%. This represents a 2.1% increase over vanilla SimSiam for the top-1 accuracy and a 1.9% increase for the F1 score. The combination of self-supervised learning and a curriculum-based approach demonstrates the efficacy of our framework in advancing the diagnosis of GI disorders. Our study highlights the potential of curriculum self-supervised learning in utilizing unlabeled GI tract images to improve the diagnosis of GI disorders, paving the way for more accurate and efficient diagnosis in GI endoscopy.


Assuntos
Currículo , Autogestão , Humanos , Endoscopia Gastrointestinal , Trato Gastrointestinal , Aprendizado de Máquina Supervisionado
2.
Sci Rep ; 12(1): 19206, 2022 11 10.
Artigo em Inglês | MEDLINE | ID: mdl-36357437

RESUMO

Brain tumor is a life-threatening disease and causes about 0.25 million deaths worldwide in 2020. Magnetic Resonance Imaging (MRI) is frequently used for diagnosing brain tumors. In medically underdeveloped regions, physicians who can accurately diagnose and assess the severity of brain tumors from MRI are highly lacking. Deep learning methods have been developed to assist physicians in detecting brain tumors from MRI and determining their subtypes. In existing methods, neural architectures are manually designed by human experts, which is time-consuming and labor-intensive. To address this problem, we propose to automatically search for high-performance neural architectures for classifying brain tumors from MRIs, by leveraging a Learning-by-Self-Explanation (LeaSE) architecture search method. LeaSE consists of an explainer model and an audience model. The explainer aims at searching for a highly performant architecture by encouraging the architecture to generate high-fidelity explanations of prediction outcomes, where explanations' fidelity is evaluated by the audience model. LeaSE is formulated as a four-level optimization problem involving a sequence of four learning stages which are conducted end-to-end. We apply LeaSE for MRI-based brain tumor classification, including four classes: glioma, meningioma, pituitary tumor, and healthy, on a dataset containing 3264 MRI images. Results show that our method can search for neural architectures that achieve better classification accuracy than manually designed deep neural networks while having fewer model parameters. For example, our method achieves a test accuracy of 90.6% and an AUC of 95.6% with 3.75M parameters while the accuracy and AUC of a human-designed network-ResNet101-is 84.5% and 90.1% respectively with 42.56M parameters. In addition, our method outperforms state-of-the-art neural architecture search methods.


Assuntos
Neoplasias Encefálicas , Aprendizado Profundo , Glioma , Neoplasias Meníngeas , Humanos , Neoplasias Encefálicas/diagnóstico por imagem , Neoplasias Encefálicas/patologia , Redes Neurais de Computação , Glioma/diagnóstico por imagem , Glioma/patologia , Imageamento por Ressonância Magnética/métodos , Encéfalo/patologia , Neoplasias Meníngeas/patologia
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