RESUMO
We report a case of primary melanoma of a female urethra diagnosed at a non-metastatic stage in a 48-year-old patient with a history of breast carcinoma treated with radiotherapy and hormone therapy. The patient was consulting for dysuria, hematuria, and perineal pain. The clinical examination found a prolapsed and black mass, developed at the expense of the urethra and located at the anterosuperior part of the vulva. The mass biopsy revealed a proliferation of fusiform and globular cells loaded with black pigment expressing the anti-HMB 45 and PS 100 antibodies. The extension assessment showed an absence of secondary localization. The patient underwent total cystourethrectomy without inguinal lymphadenectomy. There was no recurrence observed on day 100 following the surgery.
Assuntos
Neoplasias da Mama , Melanoma , Neoplasias Uretrais , Humanos , Feminino , Pessoa de Meia-Idade , Uretra/patologia , Uretra/cirurgia , Neoplasias Uretrais/diagnóstico , Neoplasias Uretrais/patologia , Neoplasias Uretrais/cirurgia , Melanoma/patologia , Vulva/patologiaRESUMO
Epidermoid cyst is an unusual and very rarely described lesion in the kidney. We report the case of a 45-year-old woman with no known pathological history who presented with right flank pain accompanied by macroscopic hematuria. The physical examination was unremarkable. The CT scan evoked a malignant tumor in front of a right renal mass with irregular contours. The patient underwent a total right nephrectomy. The nephrectomy specimen received for pathological examination showed macroscopically an encapsulated cystic mass of 4 cm long axis. The cyst lumen was occupied by solid brownish tissue debris. Histologically, the cystic wall was lined by a keratinizing squamous epithelium with accumulation of keratin lamellae in the cystic lumen. Anatomopathological examination concluded to the diagnosis of renal epidermoid cyst.
RESUMO
Primary malignant melanoma of the urethra in women is a rare tumor with a poor prognosis. We report the case of a 48-year-old patient who consulted for a mass in the urethral meatus associated with symptoms of the lower urinary tract. The result of the biopsy of the mass revealed a malignant melanoma confirmed by immunohistochemistry. The extension workup was negative. She had a total cystectomy with lymph node dissection done. The one-year follow-up was without particularity.