RESUMO
OBJECTIVE: To establish the incidence of prostate cancer (PCa) in Sicily in patients who entered an early detection protocol. METHODS: From February 2002 to February 2004, 16,298 subjects aged 40-75 entered the protocol. Patients with suspicious DRE, PSA>10 ng/ml, PSAAssuntos
Neoplasias da Próstata/epidemiologia
, Adulto
, Distribuição por Idade
, Idoso
, Biópsia por Agulha
, Humanos
, Incidência
, Masculino
, Pessoa de Meia-Idade
, Razão de Chances
, Palpação/métodos
, Prevalência
, Próstata/diagnóstico por imagem
, Próstata/patologia
, Antígeno Prostático Específico/sangue
, Neoplasias da Próstata/sangue
, Neoplasias da Próstata/diagnóstico
, Estudos Retrospectivos
, Fatores de Risco
, Sicília/epidemiologia
, Ultrassonografia
RESUMO
Deep vein thrombosis incidence is 1/1000 per year; it is associated with many risk factors which is considered as "thrombophilic states". Its pathogenesis is complex, caused by alterations of hemostasis system. Many studies have established the relation between cancer and subsequent venous thromboembolism, confirming the relationship of neoplastic cell interaction with coagulation system. Forty-seven patients admitted to the hospital from 1987 to 1996 with symptomatic clinically proved deep vein thrombosis were included in a retrospective study. Routine examination at the time of diagnosis of deep vein thrombosis revealed an occult cancer in 8 out of 47 patients; 9 out of 47 patients were admitted in hospital with vein thrombosis and known cancer. The aim of this study is to suggest the best, first treatment of vein thromboembolism in emergency to avoid the dangerous pulmonary embolism complication. The patients affected with deep vein thrombosis and cancer were elderly (over 70 years old, in mean); the neoplasia was of digestive system (8/17) in advanced metastatic stage there was cancer familiarity in 7 out of 47 patients. The high risk of pulmonary embolism associated to deep vein thrombosis suggests the importance of early starting the anticoagulant therapy and placing caval filter.