1.
Cleve Clin J Med
; 74(11): 807-10, 813-6, 2007 Nov.
Artigo
em Inglês
| MEDLINE
| ID: mdl-18020000
RESUMO
Congestive heart failure is the most common cause of death in patients with thalassemia, as chronic accumulation of iron due to regular blood transfusions leads to biventricular systolic dysfunction and death at a very young age. The quantity of iron deposited in the heart is a key determinant of outcome. Early diagnosis and intensive chelation of the cardiac iron can avert heart failure and its fatal outcome.