RESUMO
The high risk of skin cancer after organ transplantation is a major clinical challenge. We describe a case of a patient presenting with sebaceous carcinoma (SC) after a kidney transplant. Although it is exceedingly rare, SC should always be considered in the presence of any skin lesion occurring after a transplant.
RESUMO
Confluent and reticulated papillomatosis (CRP) is an underdiagnosed skin condition of uncertain etiology. The antibacterial and most importantly the anti-inflammatory mechanisms of some antibiotics seem to explain the effectiveness of these medications. Other measures such as reducing weight and treating an underlying endocrine disorder may be helpful.
RESUMO
Verrucous carcinoma (VC) of the nail bed is a rare variant of squamous cell carcinoma that is often misdiagnosed as a benign condition. The clinical presentation of this tumor is very similar to that of warts or onychomycosis hence the delayed appropriate treatment. Its association with human papillomavirus (HPV) infection has rarely been reported. The treatment of VC of the nail unit depends on the extent of the lesion and the presence or the absence of bone. We here report an unusual case of VC of the nail bed of the left big toe in a man associated with HPV53 infection that had been mistaken for a wart for 1 year. The condition was treated by ray amputation.
Assuntos
Condiloma Acuminado/complicações , Papillomavirus Humano 6/isolamento & purificação , Neoplasias Penianas/etiologia , Doenças Uretrais/complicações , Adulto , Condiloma Acuminado/patologia , Condiloma Acuminado/virologia , Humanos , Masculino , Neoplasias Penianas/patologia , Doenças Uretrais/patologia , Doenças Uretrais/virologiaRESUMO
Onychomatricoma (OM) is a rare benign tumour of the nail matrix characterized by specific clinical and histologic features. The main clinical signs are thickening of the nail plate, xanthonychia, overcurvature of the nail plate, and multiple splinter haemorrhages. The diagnosis is based on clinical, radiological and histopathological findings. Histologically, the tumour is characterized by filiform epithelial projections. The objective of this study is to present the first reported Tunisian case of OM, focusing on the contribution of magnetic resonance imaging to the diagnosis of OM. A review on the subject is also presented.
Assuntos
Carcinoma Basocelular/diagnóstico , Carcinoma Hepatocelular/diagnóstico , Neoplasias Faciais/diagnóstico , Neoplasias Hepáticas/diagnóstico , Melanoma/diagnóstico , Neoplasias Primárias Múltiplas/diagnóstico , Neoplasias Cutâneas/diagnóstico , Idoso , Amputação Cirúrgica , Carcinoma Basocelular/cirurgia , Carcinoma Hepatocelular/terapia , Embolização Terapêutica , Neoplasias Faciais/cirurgia , Dedos/patologia , Dedos/cirurgia , Humanos , Neoplasias Hepáticas/cirurgia , Masculino , Melanoma/cirurgia , Doenças da Unha/patologia , Doenças da Unha/cirurgia , Neoplasias Primárias Múltiplas/cirurgia , Neoplasias Cutâneas/cirurgiaRESUMO
Necrobiosis lipoidica is an idiopathic dermatological condition that is strongly associated with diabetes mellitus. It is more commonly seen in women than men. The average age of onset is 30-40 years. Necrobiosis Lipoidica diabeticorum is an extremely rare finding in childhood diabetes. We describe the case of a 13-year-old girl who has had type 1 diabetes mellitus since she was 8 years old. The patient presented with 2 well-defined, persistent plaques with a depressed central area and elevated purple peripheral ring, one on the right thigh and the other over the lateral left leg. Histopathologic evaluation of the patient's biopsy confirmed the diagnosis of necrobiosis lipoidica with transfollicular elimination. Our patient is the second pediatric case described with perforating necrobiosis lipoidica. We review the literature and discuss clinical features, several complications, and the most recent treatment options for necrobiosis lipoidica in diabetic children.
Assuntos
Diabetes Mellitus Tipo 1/complicações , Necrobiose Lipoídica/etiologia , Necrobiose Lipoídica/patologia , Adolescente , Biópsia por Agulha , Diabetes Mellitus Tipo 1/diagnóstico , Diabetes Mellitus Tipo 1/tratamento farmacológico , Quimioterapia Combinada , Feminino , Seguimentos , Humanos , Imuno-Histoquímica , Insulina/uso terapêutico , Extremidade Inferior , Necrobiose Lipoídica/tratamento farmacológico , Medição de Risco , Índice de Gravidade de DoençaRESUMO
Buschke-Löwenstein tumor (BLT), or giant condyloma acuminatum, is a rare sexually transmitted disease. The virus responsible for condyloma is human papillomavirus, usually serotype 6 or 11. A BLT is always preceded by condyloma acuminatum and may occur at any age after puberty. It is characterized by invasive growth and recurrence after treatment, and malignant transformation is possible. We report the case of a 44-year-old male patient with a 2-year history of a penoscrotal Buschke-Löwenstein tumor.