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2.
J Oral Implantol ; 39(2): 187-92, 2013 Apr.
Artigo em Inglês | MEDLINE | ID: mdl-23611678

RESUMO

Dentists have several treatment options when restoring patients with congenitally missing maxillary lateral incisors. Endosseous implant therapy combined with orthodontics can achieve predictable outcomes while meeting patient expectations. This case report exhibits an interdisciplinary approach involving orthodontics, implant surgery, and prosthodontics to resolve this common dental concern.


Assuntos
Anodontia/reabilitação , Incisivo/anormalidades , Equipe de Assistência ao Paciente , Adulto , Substitutos Ósseos/uso terapêutico , Cimentação/métodos , Coroas , Dente Canino/cirurgia , Implantação Dentária Endóssea/métodos , Implantes Dentários para Um Único Dente , Materiais Dentários/química , Planejamento de Prótese Dentária , Humanos , Masculino , Maxila , Osseointegração/fisiologia , Planejamento de Assistência ao Paciente , Técnicas de Movimentação Dentária/métodos , Alvéolo Dental/cirurgia , Dente Decíduo/cirurgia , Cimento de Fosfato de Zinco/química , Zircônio/química
3.
Prog Neuropsychopharmacol Biol Psychiatry ; 35(2): 459-65, 2011 Mar 30.
Artigo em Inglês | MEDLINE | ID: mdl-21122811

RESUMO

Abstinent methamphetamine (Meth) dependent individuals demonstrate poorer performance on tests sensitive to attention/information processing speed, learning and memory, and working memory when compared to non-Meth dependent individuals. The poorer performance on these tests may contribute to the morbidity associated with Meth-dependence. In light of this, we sought to determine the effects of acute, low-dose Meth administration on attention, working memory, and verbal learning and memory in 19 non-treatment seeking, Meth-dependent individuals. Participants were predominantly male (89%), Caucasian (63%), and cigarette smokers (63%). Following a four day, drug-free washout period, participants were given a single-blind intravenous infusion of saline, followed the next day by 30 mg of Meth. A battery of neurocognitive tasks was administered before and after each infusion, and performance on measures of accuracy and reaction time were compared between conditions. While acute Meth exposure did not affect test performance for the entire sample, participants who demonstrated relatively poor performance on these tests at baseline, identified using a median split on each test, showed significant improvement on measures of attention/information processing speed and working memory when administered Meth. Improved performance was seen on the following measures of working memory: choice reaction time task (p≤0.04), a 1-back task (p≤0.01), and a 2-back task (p≤0.04). In addition, those participants demonstrating high neurocognitive performance at baseline experienced similar or decreased performance following Meth exposure. These findings suggest that acute administration of Meth may temporarily improve Meth-associated neurocognitive performance in those individuals experiencing lower cognitive performance at baseline. As a result, stimulants may serve as a successful treatment for improving cognitive functioning in those Meth-dependent individuals experiencing neurocognitive impairment.


Assuntos
Transtornos Relacionados ao Uso de Anfetaminas/tratamento farmacológico , Transtornos Relacionados ao Uso de Anfetaminas/psicologia , Estimulantes do Sistema Nervoso Central/administração & dosagem , Transtornos Cognitivos/tratamento farmacológico , Metanfetamina/administração & dosagem , Adulto , Atenção/efeitos dos fármacos , Cognição/efeitos dos fármacos , Feminino , Humanos , Injeções Intraventriculares , Aprendizagem/efeitos dos fármacos , Masculino , Memória/efeitos dos fármacos , Memória de Curto Prazo/efeitos dos fármacos , Testes Neuropsicológicos , Tempo de Reação/efeitos dos fármacos , Fatores de Tempo , Aprendizagem Verbal/efeitos dos fármacos , Adulto Jovem
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