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1.
Eur J Paediatr Dent ; 22(2): 144-150, 2021 Jun.
Artigo em Inglês | MEDLINE | ID: mdl-34238006

RESUMO

AIM: This study was purposed to evaluate release of nickel and chromium ions and methyl methacrylate (MMA) monomers from functional appliances and their possible health effects. MATERIALS AND METHODS: Study design: Twin-block appliances and Bionators were immersed in artificial saliva and kept in a thermal incubator. Control group was established as artificial saliva without appliances. Artificial saliva was analysed after 7 days, 30 days and 90 days. Inductively coupled plasma mass spectrometry and gas chromatography-mass spectrometry was used for detection of nickel and chromium ions and MMA monomers. MTT assays and cytokine array were performed. STATISTICS: One way ANOVA with Tukey test and Dunnett's T3 for post-hoc analysis was used for evaluation of time-dependent changes and independent t-test was used for evaluation of MTT assay results. RESULTS: The results revealed that metal ions and MMA monomers are released from the appliances. Metal ion detection pattern was irregular and could not be analysed. Twin-block group showed significantly larger amount of MMA release. MTT assay revealed statistically significant but minimally reduced cellular activity on Bionator and twin-block groups compared to control groups. Cytokine array showed no or less inflammatory cytokine release on Bionator and twin-block groups. CONCLUSION: MMA monomer release was confirmed but the cytotoxic effect of functional appliance material release is minimal or negligible. General toxicity of the functional appliance from the MMA monomer release is likely to be minimal or negligible.


Assuntos
Níquel , Ortopedia , Cromo/toxicidade , Humanos , Metacrilatos , Metilmetacrilato/toxicidade , Níquel/toxicidade , Aparelhos Ortodônticos
2.
J Stomatol Oral Maxillofac Surg ; 120(4): 301-309, 2019 Sep.
Artigo em Inglês | MEDLINE | ID: mdl-31150839

RESUMO

PURPOSE: To investigate the submandibular soft tissue changes related to the hard tissue changes after mandibular set-back surgery in skeletal Class III patients. METHODS: The subjects were adults with skeletal Class III malocclusion who underwent orthognathic surgery including mandibular set-back between June 2007 and January 2011 at Kyung Hee University Dental Hospital at Gandong. Standardized lateral cephalograms that were taken before and 6 to 12 months after surgery were collected. Sixty samples were selected. Each lateral cephalograms was traced and lines, angles and areas associated with submandibular soft tissues were measured and analyzed statistically. RESULTS: Anteroposterior submandibular soft tissue length was reduced with reduction of mandibular body length. FH to mandibular plane angle was decreased and FH to submandibular line angle was increased. A gender difference was found in soft tissue changes. Males showed altered vertical soft tissue thickness and submandibular tissue area reduction after surgery. Several hard tissue changes were correlated with soft tissue changes and through multiple regression models with stepwise selection method, several regression equation models to predict soft tissue changes related to hard tissue changes were made. CONCLUSION: After orthognathic surgery including mandibular set-back, the submandibular soft tissue profile changes. Equations to predict submandibular soft tissue changes after mandibular set-back surgery were developed.


Assuntos
Maxila , Procedimentos Cirúrgicos Ortognáticos , Adulto , Cefalometria , Face , Humanos , Masculino , Mandíbula
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