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Phys Med Biol ; 67(3)2022 02 03.
Artigo em Inglês | MEDLINE | ID: mdl-35026744

RESUMO

Proton beam therapy can potentially offer improved treatment for cancers of the head and neck and in paediatric patients. There has been a sharp uptake of proton beam therapy in recent years as improved delivery techniques and patient benefits are observed. However, treatments are currently planned using conventional x-ray CT images due to the absence of devices able to perform high quality proton computed tomography (pCT) under realistic clinical conditions. A new plastic-scintillator-based range telescope concept, named ASTRA, is proposed here to measure the proton's energy loss in a pCT system. Simulations conducted using GEANT4 yield an expected energy resolution of 0.7%. If calorimetric information is used the energy resolution could be further improved to about 0.5%. In addition, the ability of ASTRA to track multiple protons simultaneously is presented. Due to its fast components, ASTRA is expected to reach unprecedented data collection rates, similar to 108protons/s. The performance of ASTRA has also been tested by simulating the imaging of phantoms. The results show excellent image contrast and relative stopping power reconstruction.


Assuntos
Terapia com Prótons , Telescópios , Criança , Coleta de Dados , Humanos , Processamento de Imagem Assistida por Computador , Método de Monte Carlo , Imagens de Fantasmas , Terapia com Prótons/métodos , Prótons , Tomografia Computadorizada por Raios X/métodos
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