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Georgian Med News ; (190): 28-32, 2011 Jan.
Artigo em Russo | MEDLINE | ID: mdl-21346264

RESUMO

In case of neuropathic forms, infection is the cause of tissue nekros, while - in case of neuroischemic forms, it's critical ischemia. Antibacterial therapy is present in all cases of neuroischemic form, not dependent on the signs of infection, Though, in case of neuropathic forms, a course of antibiotics is prescribed only in case of the attachment of infection. Infected neuroischemic ulcer is characterized of acube development (infection+ischemia), unlike infections neuropathic, ulces. The researches showed that 42 patients (40%) suffered from neuropathic form and 63(60%) - from neuroischemic form. In purulent zones anaerobic flora was revealed in 77.3%, aerobic flora - 17.7%, the rise of microflora was not indicated in 5% of cases. Most often, with 43.6% St. aureus was found out, and from the association of microbes - st. aureus + Str. pyogenes - 8.7%. Was the level of bacterial pollution and varied from 105 to 10(12). The highest sensibility was shown towards Tienam (98.9%). The most acceptable and productive form of treatment turned our to be the following combination phtorchinolyns+aminoglycosides. Out of 105 patients 34 amputations were done + 6 tall, 10 large (more than a half) and 18 small (up to the middle of the foot). In 71 cases we successfully managed to stop infections processes and get rid of amputations.


Assuntos
Antibacterianos/uso terapêutico , Cilastatina/farmacologia , Pé Diabético/tratamento farmacológico , Pé Diabético/cirurgia , Imipenem/farmacologia , Adulto , Idoso , Combinação Imipenem e Cilastatina , Pé Diabético/microbiologia , Pé Diabético/fisiopatologia , Combinação de Medicamentos , Feminino , Humanos , Isquemia/fisiopatologia , Masculino , Pessoa de Meia-Idade , Infecção dos Ferimentos/terapia
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