RESUMO
AIM: To evaluate the image quality and time saving using simultaneous multi-slice (SMS)-accelerated T2-weighted turbo spin echo (TSE) sequences compared to standard T2 TSE sequences in breast magnetic resonance imaging (MRI). PATIENTS AND METHODS: Thirty patients were examined with an SMS-accelerated T2 TSE sequence and a standard T2 TSE sequence as part of a breast MRI protocol at 1.5T. Image quality, signal homogeneity and tissue delineation were evaluated. For quantitative assessment, the signal-to-noise ratio (SNR) was measured from representative SNR maps. RESULTS: There were no significant differences regarding tissue delineation and signal homogeneity. Image quality was rated equal at the chest wall and the breasts but decreased in the axilla on SMS-T2 TSE (p=0.01) with a simultaneous decrease of SNR (p=0.03). This did not significantly impact the overall image quality (p=0.2). The acquisition time for SMS-T2 TSE was 48% shorter compared to standard T2 TSE. CONCLUSION: SMS-acceleration for T2-weighted imaging of the breast at 1.5T substantially reduces acquisition time while maintaining comparable quantitative and qualitative image quality. This may pave the way for protocol abbreviation especially in a high-throughput clinical workspace.
Assuntos
Neoplasias da Mama/diagnóstico por imagem , Mama/diagnóstico por imagem , Imageamento por Ressonância Magnética/métodos , Interpretação de Imagem Radiográfica Assistida por Computador/métodos , Adulto , Idoso , Estudos de Viabilidade , Feminino , Humanos , Pessoa de Meia-Idade , Razão Sinal-RuídoRESUMO
OBJECTIVE: To investigate promoting factors for background parenchymal enhancement (BPE) in MR mammography (MRM). METHODS: 146 patients were retrospectively evaluated, including 91 high-risk patients (50 BRCA patients, 41 patients with elevated lifetime risk). 56 screening patients were matched to the high-risk cases on the basis of age. The correlation of BPE with factors such as fibroglandular tissue (FGT), age, menopausal status, breast cancer, high-risk precondition as well as motion were investigated using linear regression. RESULTS: BPE positively correlated with FGT (P<.001) and negatively correlated with menopausal status (P<.001). Cancer did not show an effect on BPE (P>.05). A high-risk precondition showed a significant impact on the formation of BPE (P<.05). However, when corrected for motion, the correlation between BPE and a high-risk precondition became weak and insignificant, and a highly significant association between BPE and motion was revealed (P<.01). CONCLUSION: BPE positively correlated with FGT and negatively correlated with age. Cancer did not have an effect on BPE. A high-risk precondition appears to have a negative effect on BPE. However, when corrected for motion, high-risk preconditions became insignificant. Technical as well as physiological influences seem to play an important role in the formation of BPE.
RESUMO
PURPOSE: To examine "constant lesion sharpness" as a morphological diagnostic sign in the differential diagnosis between benign and malignant lesions. MATERIAL AND METHODS: This prospective study had institutional review board approval and was HIPAA compliant. In total 1014 consecutive patients were examined (mean age 55 years ± 13 years) and evaluated in our University hospital towards the morphological shape of the lesion borders. The "Constant sharpness Sign" was defined as a lesion remaining continuously sharp for the duration of the dynamic scan. Inclusion criteria were unclear findings (e.g. BIRADS III/IV), Preoperative staging (BRIDAS IV/V), and referred patients from local clinic of gynecology. Exclusion criteria were MRM-examination ≤1 year before, status after surgery and/or biopsy, chemotherapy and/or radiation therapy. Reference Standard was histological verification. Images were diagnosed by two experienced radiologists in consensus, blinded to the standard of reference. RESULTS: 1014 patients with 1084 lesions (436 benign, 648 malignant lesions) were included into the study. 41.5% of benign lesions and 6.8% (181/436) of malignant lesions displayed a constant sharpness as an accompanying morphological sign (P < 0.001). This resulted in a sensitivity of 41.5%, specificity of 93.2%, a positive likelihood ratio of 6.1%, a negative likelihood ratio of 0.63 and an odd's ratio of 9,7%. SUMMARY AND CONCLUSION: The constant sharpness sign seems to be an accurate predictor of benign breast lesions, which may help to increase the accuracy of MRM as a morphological sign.
RESUMO
PURPOSE: During clinical routine, we retrospectively discovered diagnostic criteria for "focal mastitis" in MR-Mammography (MRM). The aim of this study was to prospectively evaluate these criteria. METHODS: 1975 consecutive patients were examined between 01/2010 and 12/2011. 29 patients fit the diagnostic criteria of focal mastitis. RESULTS: In follow-up scans, 28 patients showed a complete remission of the previous findings. One patient was followed-up with persisting findings, which could histologically be correlated to an area of DCIS after biopsy. CONCLUSION: The morphologic, kinetic and follow-up criteria we discovered seem to be a reliable diagnostic indicator for focal mastitis.
RESUMO
PURPOSE: To demonstrate our primary findings, indicating perirenal edema as a first imaging sign towards primary hypertension. METHODS: Out of 3190 consecutive MR-Mammography (MRM) examinations, 777 were performed with an additional body array coil. Incidentally, "perirenal edema" could be linked to a patient history of hypertension. We Therefore specifically further observed the correlation. RESULTS: Of 777 patients 86 (11%) patients showed the perirenal edema sign (PES). Upon inquiry all of these cases (100%) confirmed a past or present history of hypertensive disease (i.e. blood pressure above 140/90 and/or anti-hypertensive treatment). CONCLUSION: Our preliminary results strongly indicate a strong correlation between perirenal edema and primary hypertension.