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1.
Rev. bras. med. esporte ; 29: e2022_0152, 2023. tab, graf
Artigo em Inglês | LILACS | ID: biblio-1394837

RESUMO

ABSTRACT Introduction: In today's rapid development of science and technology, digital network data mining technology is developing as fast as the expansion of the frontiers of science and technology allows, with a very broad application level, covering most of the civilized environment. However, there is still much to explore in the application of sports training. Objective: Analyze the feasibility of data mining based on the digital network of sports training, maximizing athletes' training. Methods: This paper uses the experimental analysis of human FFT, combined with BP artificial intelligence network and deep data mining technology, to design a new sports training environment. The controlled test of this model was designed to compare advanced athletic training modalities with traditional modalities, comparing the athletes' explosive power, endurance, and fitness. Results: After 30 days of physical training, the athletic strength of athletes with advanced fitness increased by 15.33%, endurance increased by 15.85%, and fitness increased by 14.23%. Conclusion: The algorithm designed in this paper positively impacts maximizing athletes' training. It may have a favorable impact on training outcomes, as well as increase the athlete's interest in the sport. Level of evidence II; Therapeutic studies - investigating treatment outcomes.


RESUMO Introdução: No rápido desenvolvimento atual de ciência e tecnologia, a tecnologia de mineração de dados de rede digital desenvolve-se tão rápido quanto a expansão das fronteiras da ciência e tecnologia permitem, com um nível de aplicação muito amplo, cobrindo a maior parte do ambiente civilizado. No entanto, ainda há muito para explorar da aplicação no treinamento esportivo. Objetivo: Análise de viabilidade da mineração de dados com base na rede digital da formação esportiva, maximizar o treinamento dos atletas. Métodos: Este trabalho utiliza a análise experimental da FFT humana, combinada com a rede de inteligência artificial da BP e tecnologia de mineração profunda de dados, para projetar um novo ambiente de treinamento esportivo. O teste controlado deste modelo foi projetado para comparar modalidades avançadas de treinamento atlético com as modalidades tradicionais, comparando o poder explosivo, resistência e condição física do atleta. Resultados: Após 30 dias de treinamento físico, a força atlética dos esportistas com aptidão física avançada aumentou 15,33%, a resistência aumentou 15,85%, e o condicionamento físico aumentou 14,23%. Conclusão: O algoritmo desenhado neste artigo tem um impacto positivo na maximização do treinamento dos atletas. Pode ter um impacto favorável nos resultados do treinamento, bem como aumentar o interesse do atleta pelo esporte. Nível de evidência II; Estudos terapêuticos - investigação dos resultados do tratamento.


RESUMEN Introducción: En el rápido desarrollo actual de la ciencia y la tecnología, la tecnología de extracción de datos de redes digitales se desarrolla tan rápido como lo permiten las fronteras en expansión de la ciencia y la tecnología, con un nivel de aplicación muy amplio que abarca la mayor parte del entorno civilizado. Sin embargo, aún queda mucho por explorar de la aplicación en el entrenamiento deportivo. Objetivo: Análisis de viabilidad de la minería de datos basada en la red digital de entrenamiento deportivo, maximizar la formación de los atletas. Métodos: Este trabajo utiliza el análisis experimental de la FFT humana, combinado con la red de inteligencia artificial BP y la tecnología de minería de datos profunda, para diseñar un nuevo entorno de entrenamiento deportivo. La prueba controlada de este modelo se diseñó para comparar las modalidades de entrenamiento atlético avanzado con las modalidades tradicionales, comparando la potencia explosiva, la resistencia y la forma física del atleta. Resultados: Después de 30 días de entrenamiento físico, la fuerza atlética de los atletas con un estado físico avanzado aumentó en un 15,33%, la resistencia aumentó en un 15,85% y el estado físico aumentó en un 14,23%. Conclusión: El algoritmo diseñado en este trabajo tiene un impacto positivo en la maximización del entrenamiento de los atletas. Puede tener un impacto favorable en los resultados del entrenamiento, así como aumentar el interés del atleta por el deporte. Nivel de evidencia II; Estudios terapéuticos - investigación de los resultados del tratamiento.


Assuntos
Humanos , Inteligência Artificial , Aptidão Física/fisiologia , Redes Neurais de Computação , Desempenho Atlético/fisiologia , Atletas
2.
J Healthc Eng ; 2021: 5528622, 2021.
Artigo em Inglês | MEDLINE | ID: mdl-33884157

RESUMO

Breast cancer forms in breast cells and is considered as a very common type of cancer in women. Breast cancer is also a very life-threatening disease of women after lung cancer. A convolutional neural network (CNN) method is proposed in this study to boost the automatic identification of breast cancer by analyzing hostile ductal carcinoma tissue zones in whole-slide images (WSIs). The paper investigates the proposed system that uses various convolutional neural network (CNN) architectures to automatically detect breast cancer, comparing the results with those from machine learning (ML) algorithms. All architectures were guided by a big dataset of about 275,000, 50 × 50-pixel RGB image patches. Validation tests were done for quantitative results using the performance measures for every methodology. The proposed system is found to be successful, achieving results with 87% accuracy, which could reduce human mistakes in the diagnosis process. Moreover, our proposed system achieves accuracy higher than the 78% accuracy of machine learning (ML) algorithms. The proposed system therefore improves accuracy by 9% above results from machine learning (ML) algorithms.


Assuntos
Neoplasias da Mama , Algoritmos , Mama/diagnóstico por imagem , Neoplasias da Mama/diagnóstico por imagem , Feminino , Humanos , Aprendizado de Máquina , Redes Neurais de Computação
3.
Mymensingh Med J ; 30(1): 79-84, 2021 Jan.
Artigo em Inglês | MEDLINE | ID: mdl-33397855

RESUMO

Oral submucous fibrosis (OSF) is a chronic complex potentially pre-malignant condition caused by chewing areca nut and other irritants. It is an insidious process characterized by Juxta-epithelial deposition of fibrous tissue in the oral cavity and pharynx. OSF is very common in Southeast Asia and also now a days increase in Europe and North America. The aim of this study to compare the effectiveness of intralesional injection of triamcinolone and hyalurunidase versus intralesional injection of triamcinolone plus injection hyalurunidase with oral colchicine. The study included 60 patients of clinically diagnosed case of oral submucous fibrosis. Patients were divided into two Groups A and B. Group A patients received combination intralesionsl injection of triamcinolone acetonide 10mg/ml in 1ml with injection hyalurunidase 1500IU in 2ml with injection 2% lidocaine 7ml. 15 days interval in 3 months and Group B received intralesional injection of triamcinolone acetonide 10mg/ml in 1ml with injection hyalurunidase 1500IU in 2ml with injection 2% lidocaine 7ml in each 15 days interval for 3 months with oral colchicine 0.5mg twice daily for 3 months. Diagnosis based on burning sensation of mouth, blanching of mucosa, ulceration in oral cavity and also reduced mouth opening. Follow up assessment was done at intervals 1st follow up on 21st days after starting of treatment then 2nd follow up after 3 months and last 3rd follow up after 6 months. Before starting of treatment all patients were properly explained about the study and took their written consent. Much more improvement occurred in Group B patients, reducing in burning sensation and also increases in opening of mouth. In both groups blanching mucosae were improved. Treatment regimen of Group B is more effective in increasing mouth opening and improves burning sensation of oral cavity. No side effects were seen in both groups' patients.


Assuntos
Fibrose Oral Submucosa , Triancinolona Acetonida , Areca , Colchicina , Humanos , Fibrose Oral Submucosa/tratamento farmacológico , Resultado do Tratamento
4.
Mymensingh Med J ; 29(3): 560-567, 2020 Jul.
Artigo em Inglês | MEDLINE | ID: mdl-32844794

RESUMO

Variety of conditions may be responsible for low back pain but lumber spinal canal stenosis is an important cause of low back pain. Lumber spinal canal stenosis usually presents with low backache with neurogenic claudication and shortness of walking distance in adult patient. Surgical management of lumbar spinal canal stenosis by decompression surgery is effective method. This prospective interventional study was performed in patient with clinical features like low back pain with radicular pain, neurogenic claudication, signs of root compression, positive MRI findings attending in department of Orthopaedic Surgery Mymensingh Medical College Hospital and Private Hospital from July 2016 to June 2019. Thirty patients were evaluated among those 20(66.6%) were 50 years and above. The mean age was 47.5±1.6 years. Male to female ratio was roughly 8:1. Almost all of the patients had low backache with radiation to the back of the thigh and leg with motor weakness (60%). About 66.6% of the patients had sensory deficit and 83.3% had neurogenic claudication. Majority (80.0%) of the patients at presentation had a suffering of 12 or >12 months. The mean duration of suffering was 14.7±5.1 months. About 55% of the patients were able to perform heel-walking and 36.0% tip-toe walking. Nearly 57% of the patients had sensory deficit along the distribution of 1st sacral nerve and 53.3% along the distribution of lumber 5 nerves. Diagnosis shows that 16.6% of patients had L4 lesion, 50% L5, 10.0% patients had L4 & L5 and 46.6% S1. Laminectomy was done in 26.6% of patients, laminectomy and disectomy in 33.3% and laminectomy, discectomy & foraminal decompression in 40.0% of patients. Twenty five (83.5%) of patients was free from symptoms. Eighty percent (80.0%) of patients shows minimal disability and 20.0% moderate disability on the basis of Oswestry Disability Index, while by MacNab criteria, most (80%) of patients was excellent, 10% good and another 10% fair. Repeated measure ANOVA statistics showed that mean Oswestry score decreased significantly from 54.5% at baseline to 22% at the end of 1 year (p<0.001).


Assuntos
Laminectomia , Estenose Espinal/cirurgia , Adulto , Constrição Patológica , Descompressão Cirúrgica , Feminino , Humanos , Vértebras Lombares/cirurgia , Masculino , Pessoa de Meia-Idade , Estudos Prospectivos , Canal Medular/cirurgia , Resultado do Tratamento
5.
Mymensingh Med J ; 29(2): 284-289, 2020 Apr.
Artigo em Inglês | MEDLINE | ID: mdl-32506080

RESUMO

Many patients come with open fracture tibia-fibula initially managed by surgical toileting and the application of indigenous uniaxial external fixator in our country. Many of them lead to non-uniting fracture or sometimes signs of union absent within 4 months from the time of initial fracture and become infected also. This quasi experimental study included 40 skeletally matured patients was conducted from 05 February 2014 to 05 February 2018 in the department of Orthopedics, Mymensingh Medical College Hospital, Mymensigh, Bangladesh. The purpose of this study was to evaluate the efficacy of Ilizarov external fixator for treatment of infected gap non-uniting mid shaft tibia-fibula fracture which was initially open fracture Gustilo II to Gustilo III B. Uniaxial external fixators were replaced by to Ilizarov external fixators which multiaxial. Here male 30(75%), female 10(25%) with mean 28 years of age were analyzed in this study based on the inclusion criteria. Twenty eight (70%) fractures had right tibia-fibula while 12(30%) fracture had involved left tibia-fibula. Twelve (30%) patients had a grade II, grade III A- 18(45%), grade IIIB- 10(25%) open fracture tibia-fibula according to the Gustilo and Anderson classification. Initial mode of injury RTA was 28(70%), fall from height 8(20%), physical assault 4(10%). Mean interval between initial trauma and Ilizarov external fixator application was 4.4 months (ranges 4.2-4.8 months).Union or signs of union achieved in all cases in an average time of 17.12 weeks (range 14-20 weeks). The Ilizarov fixator was kept for an average period of 195 days (range 180-210 days). Minimal follow-up was 9 months after complete frame removal (average: 12 months, range: 9-18 months). Based on ASAMI scoring system, bony and functional results were assessed. The bony results were excellent in 24(60%), good in 12(30%), fair in 4(10%) and the Functional results were excellent in 18(45%), good in 16(40%), fair in 4(10%) and poor in 2(5%). In 16(40%) patients 20 wires had pin tract infection in this series. Most pin-tract infections healed well with regular dressing and oral antibiotics but in 8(20%) patients 8 affected loose wires were exchanged. Limb length discrepancy was 1.5cm in 18(45%) patients and 2.0cm in 22(55%) patients. The small sample sizes and short duration of follow-up were the study limitations. We need a life boat or life jacket during journey. As Orthopeadic Surgeon we are always in danger and Ilizarov method is the life boat technology in orthopedic surgery. It restores bone biology without disturbing the medullary cavity. To avoid repeated surgical intervention and to reduce the cost of treatment, we suggest that gap non-uniting infected tibia-fibula fracture which was primarily open should be fixed by Ilizarov external fixator than continuing treatment with indigenous uniaxial external fixator.


Assuntos
Fíbula , Técnica de Ilizarov , Adulto , Bangladesh , Fixadores Externos , Feminino , Consolidação da Fratura , Humanos , Masculino , Tíbia , Resultado do Tratamento
6.
Mymensingh Med J ; 28(1): 200-205, 2019 Jan.
Artigo em Inglês | MEDLINE | ID: mdl-30755570

RESUMO

We examined the hypothesis that the cross mattress for chest drain insertion site security is better than that of polypropylene horizontal mattress in chest trauma patient required tube thoracostomy at the Department of Casualty Surgery, Dhaka Medical College Hospital, Dhaka, Bangladesh from January 2016 to June 2016. Accordingly we prospectively studied 50 consecutive patients who needed chest tube insertion. In 25 consecutive cases chest drain insertion site was secured with polypropylene horizontal mattress technique (Control- Group A) and another 25 consecutive patients had a cross-mattress with non-absorbable suture materials (Experimental- Group B). All chest tubes were inserted into the triangle of safety to following the BTS guideline. A baseline x-ray chest was compared with post-procedure chest x-ray. Male preponderance and young adults were comprised in both the groups; mean age in Group A and Group B was 38.7±15.5 and 37.3±14.1 respectively. Haemo-pneumothorax was the most common cause of tube thoracostomy among the trauma victims. This study shows that, polypropylene horizontal mattress results in increased chest tube site infection 52% in Control Group vs. 12% in Experimental Group (p=0.002). Although there was similar incidence of blood loss between the groups, the length of Hospital stay was significantly higher in Control Group. We conclude that cross mattress for chest drain insertion site security showed a better clinical outcome, less wound complications and less hospitalization.


Assuntos
Tubos Torácicos , Hemotórax/cirurgia , Pneumotórax/cirurgia , Sucção/métodos , Traumatismos Torácicos/cirurgia , Toracostomia/métodos , Bangladesh , Hemotórax/etiologia , Humanos , Masculino , Pneumotórax/etiologia , Estudos Prospectivos , Sucção/instrumentação , Traumatismos Torácicos/complicações , Toracostomia/instrumentação , Adulto Jovem
7.
BMC Complement Altern Med ; 16: 157, 2016 May 31.
Artigo em Inglês | MEDLINE | ID: mdl-27246877

RESUMO

BACKGROUND: Amaranthus (Amaranthaceae) has previously been reported to possess different bioactive phytochemicals including phenols, tannins and flavonoids. The current study was designed to evaluate the antioxidant, anti-proliferative and antimicrobial activity of stem and seed extracts of Amaranthus lividus (AL) and Amaranthus hybridus (AH), respectively. METHODS: Antioxidant activity of methanol extract was assessed by DPPH radical scavenging assay. Determination of lectin activity of Amaranthus extract was carried out using hemagglutination assay on mouse blood. A total of thirty six Swiss albino mice containing Ehrlich's ascites carcinoma (EAC) cells were treated with AL and AH extract at 25, 50 and 100 µg/ml/day/mouse for six days. Growth inhibitory activity was determined by haemocytometer counting of EAC cells using trypan blue dye and DAPI (4΄,6-diamidino-2-phenylindole) staining was used to assess apoptotic cells. Gene amplification study was conducted to observe the expression pattern of p53, Bax, Bcl-2 and caspase-3 mRNA using PCR (polymer chain reaction) technique. In vitro susceptibility of five pathogenic bacteria including Escherichia coli, Pseudomonas aeruginosa, Bacillus subtilis, Salmonella typhi and Staphylococcus aureus was detected using disk diffusion assay. RESULTS: The radical scavenging assay indicated that AH and AL possesses potent antioxidant potential, exhibiting IC50 value of 28 ± 1.5 and 93 ± 3.23 µg/ml, respectively. Hemagglutination assay revealed that AH and AL agglutinated mice blood at 1.565 and 3.125 µg/wall, respectively. Administration of AH and AL extract led to 45 and 43 % growth inhibition of EAC cells, respectively at 100 µg/ml with marked features of apoptosis including cell shrinkage, condensation of cytoplasm and aggregation of apoptotic bodies etc. Up-regulation of p53, Bax and caspase-3 and down-regulation of Bcl-2 mRNA in Amaranthus treated mice indicated mitochondria mediated apoptosis of EAC cells in comparison with control. None of the bacterial species showed susceptibility to the extract of both the Amaranthus species. CONCLUSION: Our current findings suggest that both of the Amaranthus species have strong antioxidant, lectin and anti-proliferative activity on EAC cells. The current anticancer potential was observed due mainly to the mitochondria mediated apoptosis of EAC cells.


Assuntos
Amaranthus/química , Anti-Infecciosos/farmacologia , Antineoplásicos Fitogênicos/farmacologia , Antioxidantes/farmacologia , Extratos Vegetais/farmacologia , Animais , Bangladesh , Compostos de Bifenilo , Carcinoma de Ehrlich , Ensaios de Seleção de Medicamentos Antitumorais , Feminino , Indóis/metabolismo , Camundongos , Testes de Sensibilidade Microbiana , Picratos , Verduras/química
8.
Mymensingh Med J ; 25(1): 141-7, 2016 Jan.
Artigo em Inglês | MEDLINE | ID: mdl-26931264

RESUMO

The objective of this retrospective study was to investigate the clinical effectiveness of nerve root blocks (i.e., periradicular injection of Lidocaine and triamcinolone) for lumbar monoradiculopathy in patients with a mild neurological deficit in National Institute of Traumatology & Orthopaedic Rehabilitation (NITOR), Dhaka, Bangladesh from March 2014 to December 2014. We Included 24 patients (32-74 years) with a minor sensory/motor deficit and an unequivocal MRI finding (18 disc herniations, 6 foraminal stenosis) treated with a selective nerve root block. Based on the clinical and imaging findings, surgery (decompression of the nerve root) was justifiable in all cases. Seventeen patients (87%) had rapid (1-4 days) and substantial regression of pain, four required a repeat injection. Sixty percent (60%) of the patients with disc herniation or foraminal stenosis had permanent resolution of pain, so that an operation was avoided over an average of 6 months (2-9 months) follow-up. Nerve root blocks are very effective in the non-operative treatment of minor monoradiculopathy and should be recommended as the initial treatment of choice for this condition.


Assuntos
Deslocamento do Disco Intervertebral/tratamento farmacológico , Lidocaína/uso terapêutico , Vértebras Lombares/fisiopatologia , Manejo da Dor , Triancinolona/uso terapêutico , Adulto , Idoso , Bangladesh , Constrição Patológica/tratamento farmacológico , Humanos , Perna (Membro)/fisiopatologia , Pessoa de Meia-Idade , Bloqueio Nervoso , Radiculopatia , Estudos Retrospectivos
9.
Mymensingh Med J ; 25(1): 168-75, 2016 Jan.
Artigo em Inglês | MEDLINE | ID: mdl-26931270

RESUMO

Castleman's disease is a rare primary disease of the lymph nodes. Little is known about the management of the disease. Surgical treatment gives a very good result. What other modalities of treatment could be done is not yet established. The role of surgery gives good result and follow up evaluation is satisfactory. We found a solitary intra-abdominal mass of lymphoid hyperplasia with a histological diagnosis of Castlemans disease identified in the pathological data base. Unicentric disease was defined as it was a solitary mass. Clinical, Radiological and Laboratory data were analysed to evaluate treatment response. The patient also has related disorders as Acanthosis nigricans, Myoneuronal disorder as-MG and bronchiolitis. The patient diagnosed as angiofollicular hyperplasia (Castleman's disease). After evaluation patient under went surgical treatment, partial excision of tumor mass due to morbid adhesion with inferior vena cava. The patient becomes symptom free and lump disappears within 60 days of treatment. There was no recurrence of the disease after further evaluation. The author recommends that in Unicentric variant of Castlemans disease surgical resection of the tumor is curative. The unicentric tumour may be hyaline-vascular or hyaline-vascular/ plasma cell type. Partial resection, Radiotherapy or observation alone may avoid excessive aggressive therapy.


Assuntos
Hiperplasia do Linfonodo Gigante/diagnóstico , Hiperplasia do Linfonodo Gigante/cirurgia , Acantose Nigricans/diagnóstico , Acantose Nigricans/etiologia , Bangladesh , Bronquiolite/diagnóstico , Bronquiolite/etiologia , Hiperplasia do Linfonodo Gigante/etiologia , Hiperplasia do Linfonodo Gigante/patologia , Humanos , Masculino , Pessoa de Meia-Idade , Miastenia Gravis/diagnóstico , Miastenia Gravis/etiologia , Resultado do Tratamento
10.
Mymensingh Med J ; 15(2): 204-7, 2006 Jul.
Artigo em Inglês | MEDLINE | ID: mdl-16878106

RESUMO

Hyper reactive malarial splenomegaly (HMS) is a relatively rare chronic complication of malaria. Previous name of the disease was Tropical splenomegaly syndrome (TSS). It is seen in endemic zone of malaria. In Bangladesh it is very rare. It is more prevalent in Africa, India, Sri Lanka, Thailand etc. It is due to abnormal immune response to malaria. Recently we got a typical case of HMS in our pediatric department of Community Based Medical College Hospital (CBMCH) Mymensingh. The patient, a seven years old boy came from Haluaghat, Mymensingh, which is a hyper endemic zone of malaria. The boy had history of repeated attack of malaria with huge chronic splenomegaly for five years. Antibody to malaria was positive & titer was markedly raised. Other causes of massive splenomegaly namely chronic Kala azar, Typhoid, congenital hemolytic anemia, Leukaemia, Lymphoma etc were excluded by laboratory examination. The boy was discharged with malaria prophylaxis for a long time & advised to come to our unit every month for further follow up.


Assuntos
Malária/complicações , Esplenomegalia/parasitologia , Antimaláricos/uso terapêutico , Criança , Diagnóstico Diferencial , Humanos , Malária/diagnóstico , Malária/tratamento farmacológico , Masculino , Esplenomegalia/diagnóstico
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