[Post-radiation communicative induction of blood and immunity disorders]. / Postradiatsionnaia kommunikativnaia induktsiia narushenii krovi i immuniteta.

Intact rats and mice were kept in one cage with irradiated rats and mice. Measurements of leukocyte and nuclear neutrophils counts in the peripheral blood, weight of the thymus and immune reactivity int he intact animals indicated that 1-2 weeks of sharing cage with irradiated animals produced a fall in the above values compared to those of the controls. This seems to be a reaction to changed behavior of the irradiated animals. The intact ones experienced anxiety which may provoke the above disorders.

[The combined action of ionizing radiation and stress on antibody formation in mice]. / Sochetannoe vozdeistvie ioniziruiushchei radiatsii i stressa na antitelogenez u myshei.

Disturbances in humoral immune response to sheep erythrocytes after separate and combined effect of ionizing radiation (2 and 4 Gy) and stress (swimming for 10 of 60 min) was studied in mice. The increase in sensitivity to stress was found in irradiated mice. Superposition of undulating dynamics of post-stress immunosuppression on dynamics of post-radiation disorder was revealed. This is due to the different mechanisms of disturbances: redistribution of precursors of immunocompetent cells between immune organs in the first case and destruction of cells in the second case.

[Immunopharmacological analysis of secondary postradiation immunodeficiency]. / Immunofarmakologicheskii analiz vtorichnogo postluchevogo immunodefitsita.

A model for secondary postradiation immunodeficiency of mice has been used to compare immunocorrective activities of some new immunomodulators (arbidol, cagocel, myelopid, proleukinferon and fragmine) administered at late times (2-3 months) after exposure to a nonlethal radiation dose (4.0 Gy). The highest immunocorrective effect has been shown with fragmine and proleukinferon.

Congenital pulmonary arteriovenous aneurysms.

The authors analyse their diagnostic and therapeutic experience with 26 patients suffering from congenital pulmonary arteriovenous aneurysms. Symptoms of the disease were found to depend directly on the presence and volume of arterial blood shunted into the venous bed. The volume of shunted nonoxygenated blood varied between 20 and 48 p.c.; the reflux caused hypoxic hypoxaemia with HbO2art. = 91.2 +/- 1.43%; pO2art. = 63.6 +/- 5.54 mmHg. Aimed tomography and pulmonary angiography proved most advantageous in terms of diagnostic; with their aid it was possible to identify three variants of congenital pulmonary arteriovenous aneurysm: isolated, multiple and "of the capillary haemangioma type".

[Surgical correction of congenital arteriovenous aneurysms of the lungs]. / Khirurgicheskaia korrektsiia vrozhdennykh arteriovenoznykh anevrizm legkikh.

The authors have analyzed results of the surgical treatment of 24 out of 26 patients observed at the clinic for arterio-venous aneurysms of the lungs. It was found that the reduction of efficiency of the gas exchange function of the lungs before operation manifested itself by arterial and venous hypoxemia with an increased arterio-venous oxygen difference and pronounced decrease of blood oxygen strain. Good results of the operative treatment, rapid recovery of blood oxygenation, disappearance of hypoxemia symptoms make the surgical method the only radical one in treatment of such patients. The operation of choice was lobectomy. No lethal outcomes followed.