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BACKGROUND: In the National Academies of Sciences, Engineering, and Medicine 2016 report on trauma care, the establishment of a National Trauma Research Action Plan to strengthen and guide future trauma research was recommended. To address this recommendation, the Department of Defense funded the Coalition for National Trauma Research to generate a comprehensive research agenda spanning the continuum of trauma and burn care. We describe the gap analysis and high-priority research questions generated from the National Trauma Research Action Plan panel on long-term outcomes. METHODS: Experts in long-term outcomes were recruited to identify current gaps in long-term trauma outcomes research, generate research questions, and establish the priority for these questions using a consensus-driven, Delphi survey approach from February 2021 to August 2021. Panelists were identified using established Delphi recruitment guidelines to ensure heterogeneity and generalizability including both military and civilian representation. Panelists were encouraged to use a PICO format to generate research questions: Patient/Population, Intervention, Compare/Control, and Outcome model. On subsequent surveys, panelists were asked to prioritize each research question on a 9-point Likert scale, categorized to represent low-, medium-, and high-priority items. Consensus was defined as ≥60% of panelists agreeing on the priority category. RESULTS: Thirty-two subject matter experts generated 482 questions in 17 long-term outcome topic areas. By Round 3 of the Delphi, 359 questions (75%) reached consensus, of which 107 (30%) were determined to be high priority, 252 (70%) medium priority, and 0 (0%) low priority. Substance abuse and pain was the topic area with the highest number of questions. Health services (not including mental health or rehabilitation) (64%), mental health (46%), and geriatric population (43%) were the topic areas with the highest proportion of high-priority questions. CONCLUSION: This Delphi gap analysis of long-term trauma outcomes research identified 107 high-priority research questions that will help guide investigators in future long-term outcomes research. LEVEL OF EVIDENCE: Diagnostic Tests or Criteria; Level IV.
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Avaliação de Resultados em Cuidados de Saúde , Projetos de Pesquisa , Idoso , Humanos , Técnica Delphi , Consenso , Inquéritos e QuestionáriosRESUMO
OBJECTIVE: To determine whether reformatted computed tomography (CT) scans would increase surgeons' confidence in placing a trans sacral (TS) screw in the first sacral segment. SETTING: Level 1 trauma center. DESIGN: A retrospective cohort study. PATIENTS/PARTICIPANTS: There were 50 patients with uninjured pelvises who were reviewed by 9 orthopaedic trauma fellowship-trained surgeons and 5 orthopaedic residents. MAIN OUTCOME MEASUREMENTS: The overall percentage of surgeons who believe it was safe to place a TS screw in the first sacral segment with standard (axial cuts perpendicular to the scanner gantry) versus reformatted (parallel to the S1 end plate) CT scans. RESULTS: Overall, 58% of patients were believed to have a safe corridor in traditional cut axial CT scans, whereas 68% were believed to have a safe corridor on reformatted CT scans ( P < 0.001). When grouped by dysplasia, those without sacral dysplasia (n = 28) had a safe corridor 93% of the time on traditional scans and 93% of the time with reformatted CT scans ( P = 0.87). However, of those who had dysplasia (n = 22), only 12% were believed to have a safe corridor on original scans compared with 35% on reformatted scans ( P < 0.001). CONCLUSIONS: CT scan reformatting parallel to the S1 superior end plate increases the likelihood of identifying a safe corridor for a TS screw, especially in patients with evidence of sacral dysplasia. The authors would recommend the routine use of reformatting CT scans in this manner to provide a better understanding of the upper sacral segment osseous fixation pathways.
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Parafusos Ósseos , Sacro , Placas Ósseas , Fixação Interna de Fraturas/métodos , Humanos , Estudos Retrospectivos , Sacro/diagnóstico por imagem , Sacro/cirurgia , Tomografia Computadorizada por Raios XRESUMO
BACKGROUND: To date, little has been published comparing the structure and requirements of orthopedic training programs across multiple countries. The goal of this study was to summarize and compare the characteristics of orthopedic training programs in the U.S.A., U.K., Canada, Australia, Germany, India, China, Saudi Arabia, Russia and Iran. METHODS: We communicated with responders using a predetermined questionnaire regarding the national orthopedic training program requirements in each respondent's home country. Specific items of interest included the following: the structure of the residency program, the time required to become an orthopedic surgeon, whether there is a log book, whether there is a final examination prior to becoming an orthopedic surgeon, the type and extent of faculty supervision, and the nature of national in-training written exams and assessment methods. Questionnaire data were augmented by reviewing each country's publicly accessible residency training documents that are available on the web and visiting the official website of the main orthopedic association of each country. RESULTS: The syllabi consist of three elements: clinical knowledge, clinical skills, and professional skills. The skill of today's trainees predicts the quality of future orthopedic surgeons. The European Board of Orthopedics and Traumatology (EBOT) exam throughout the European Union countries should function as the European board examination in orthopedics. We must standardize many educational procedures worldwide in the same way we standardized patient safety. CONCLUSION: Considering the world's cultural and political diversity, the world is nearly unified in regards to orthopedics. The procedures (structure of the residency programs, duration of the residency programs, selection procedures, using a log book, continuous assessment and final examination) must be standardized worldwide, as implemented for patient safety. To achieve this goal, we must access and evaluate more information on the residency programs in different countries and their needs by questioning them regarding what they need and what we can do for them to make a difference.
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Over the past 3 decades, the evolution of pelvic and acetabular surgery has been supported by the advances in intraoperative pelvic fluoroscopic imaging technology. The new Ziehm RFD 3D C-arm unit provides routine fluoroscopic pelvic imaging but also offers rapid and high-quality real-time axial, sagittal, and coronal intraoperative imaging. This technology allows the surgeon to accurately assess fracture reduction, loose body removal, and implant locations while the patient is still under anesthesia. In this way, any necessary corrections can be performed before the patient leaves the operating room. Essentially, this technology should eliminate the need for revision surgeries. In this report, we present our initial experience using this new device.
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Fluoroscopia/instrumentação , Fixação Interna de Fraturas , Fraturas Ósseas/diagnóstico por imagem , Fraturas Ósseas/cirurgia , Cuidados Intraoperatórios/métodos , Ossos Pélvicos/diagnóstico por imagem , Ossos Pélvicos/cirurgia , Acetábulo/diagnóstico por imagem , Acetábulo/lesões , Acetábulo/cirurgia , Desenho de Equipamento , Humanos , Cuidados Intraoperatórios/normas , Ossos Pélvicos/lesõesRESUMO
INTRODUCTION: On evaluation of the clinical indications of computed tomography (CT) scan of head in the patients with low-energy geriatric hip fractures, Maniar et al. identified physical evidence of head injury, new onset confusion, and Glasgow Coma Scale (GCS)<15 as predictive risk factors for acute findings on CT scan. The goal of the present study was to validate these three criteria as predictive risk factors for a larger population in a wider geographical distribution. PATIENTS AND METHODS: Patients ≥65 years of age with low-energy hip fractures from 6 trauma centers in a wide geographical distribution in the United States were included in this study. In addition to the relevant patient demographic findings, the above mentioned three criteria and acute findings on head CT scan were gathered as categorical variables. RESULTS: In total 799 patients from 6 centers were included in the study. There were 67 patients (8.3%) with positive acute findings on head CT scan. All of these patients (100%) had at least one criteria positive. There were 732 patients who had negative acute findings on head CT scan with 376 patients (51%) having at least one criteria positive and 356 patients (49%) having no criteria positive. Sensitivity of 100% and negative predictive value of 100% was observed to predict negative acute findings on head CT scan when all the three criteria were negative. CONCLUSION: With the observed 100% sensitivity and 100% negative predictive value, physical evidence of acute head injury, acute retrograde amnesia, and GCS<15 can be recommended as a clinical decision guide for the selective use of head CT scans in geriatric patients with low energy hip fractures. All the patients with positive acute head CT findings can be predicted in the presence of at least one positive criterion. In addition, if these criteria are used as a pre-requisite to order the head CT, around 50% of the unnecessary head CT scans can be avoided.
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Traumatismos Craniocerebrais/diagnóstico por imagem , Avaliação Geriátrica/métodos , Fraturas do Quadril/diagnóstico por imagem , Tomografia Computadorizada por Raios X , Centros de Traumatologia , Procedimentos Desnecessários , Idoso , Tomada de Decisão Clínica , Feminino , Seguimentos , Fraturas do Quadril/cirurgia , Humanos , Masculino , Tomografia Computadorizada por Raios X/estatística & dados numéricos , Estados UnidosRESUMO
BACKGROUND: With the changing delivery of orthopaedic surgical care, there is a need to define the knowledge and competencies that are expected of an orthopaedist providing general and/or acute orthopaedic care. This article provides a proposal for the knowledge and competencies needed for an orthopaedist to practice general and/or acute care orthopaedic surgery. METHODS: Using the modified Delphi method, the General Orthopaedic Competency Task Force consisting of stakeholders associated with general orthopaedic practice has proposed the core knowledge and competencies that should be maintained by orthopaedists who practice emergency and general orthopaedic surgery. RESULTS: For relevancy to clinical practice, 2 basic sets of competencies were established. The assessment competencies pertain to the general knowledge needed to evaluate, investigate, and determine an overall management plan. The management competencies are generally procedural in nature and are divided into 2 groups. For the Management 1 group, the orthopaedist should be competent to provide definitive care including assessment, investigation, initial or emergency care, operative or nonoperative care, and follow-up. For the Management 2 group, the orthopaedist should be competent to assess, investigate, and commence timely non-emergency or emergency care and then either transfer the patient to the appropriate subspecialist's care or provide definitive care based on the urgency of care, exceptional practice circumstance, or individual's higher training. This may include some higher-level procedures usually performed by a subspecialist, but are consistent with one's practice based on experience, practice environment, and/or specialty interest. CONCLUSIONS: These competencies are the first step in defining the practice of general orthopaedic surgery including acute orthopaedic care. Further validation and discussion among educators, general orthopaedic surgeons, and subspecialists will ensure that these are relevant to clinical practice. CLINICAL RELEVANCE: These competencies provide many stakeholders, including orthopaedic educators and orthopaedists, with what may be the minimum knowledge and competencies necessary to deliver acute and general orthopaedic care. This document is the first step in defining a practice-based standard for training programs and certification groups.
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Competência Clínica/normas , Cirurgiões Ortopédicos/normas , Ortopedia/normas , Traumatismos em Atletas/cirurgia , Comunicação , Doenças do Pé/cirurgia , Fraturas Ósseas/cirurgia , Mãos/cirurgia , Humanos , Pessoa de Meia-Idade , Padrões de Prática Médica/normas , Doenças da Coluna Vertebral/diagnóstico , Doenças da Coluna Vertebral/cirurgia , Medicina Esportiva/normasRESUMO
OBJECTIVE: To examine the association between antibiotic timing and deep infection of type III open tibia fractures. DESIGN: Retrospective prognostic study. SETTING: Level 1 Trauma Center. PATIENTS: The study population included 137 patients after exclusions for missing data (13), nonreconstructible limbs (9), and/or absence of 90-day outcome data (3). INTERVENTION: An observational study of antibiotic timing. MAIN OUTCOME MEASUREMENT: Deep infection within 90 days. RESULTS: Age, smoking, diabetes, injury severity score, type IIIA versus 3B/C injury, and time to surgical debridement were not associated with infection on univariate analysis. Greater than 5 days to wound coverage (P < 0.001) and greater than 66 minutes to antibiotics (P < 0.01) were univariate predictors of infection. Multivariate analysis found wound coverage beyond 5 days [odds ratio, 7.39; 95% confidence interval (CI), 2.33-23.45; P < 0.001] and antibiotics beyond 66 minutes (odds ratio, 3.78; 95% CI, 1.16-12.31; P = 0.03) independently predicted infection. Immediate antibiotics and early coverage limited the infection rate (1 of 36, 2.8%) relative to delay in either factor (6 of 59, 10.2%) or delay in both factors (17 of 42, 40.5%). CONCLUSIONS: Time from injury to antibiotics and to wound coverage independently predict infection of type III open tibia fractures. Both should be achieved as early as possible, with coverage being dependent on the condition of the wound. Given the relatively short therapeutic window for antibiotic prophylaxis (within an hour of injury), prehospital antibiotics may substantially improve outcomes for severe open fractures. LEVEL OF EVIDENCE: Prognostic Level II. See Instructions for Authors for a complete description of levels of evidence.
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Antibacterianos/administração & dosagem , Fraturas Expostas/cirurgia , Infecção da Ferida Cirúrgica/prevenção & controle , Fraturas da Tíbia/cirurgia , Adulto , Antibioticoprofilaxia , Fraturas Expostas/complicações , Humanos , Pessoa de Meia-Idade , Prognóstico , Estudos Retrospectivos , Infecção da Ferida Cirúrgica/etiologia , Fraturas da Tíbia/complicações , Fatores de TempoRESUMO
BACKGROUND: A comprehensive system has been developed by the AO Classification Advisory Group to allow in-depth classification of scapular fractures for clinical research and surgical decision making. This paper evaluates a detailed classification system of scapular body fractures to better address the need for clinical relevance. METHODS: Seven experienced shoulder and orthopaedic trauma specialist surgeons participated in a follow-up series of agreement studies to specify and to evaluate the involvement of the body in scapula fractures. The last evaluation was conducted on a consecutive collection of 120 scapula fractures. RESULTS: There was agreement in 82% of the 120 cases with an overall κ of 0.75 when the surgeons identified body (B) fractures. Surgeons were in full agreement about involvement of the lateral inferior, medial, and superior borders in 72%, 51%, and 69% of the 101 cases identified with body involvement, respectively. The proportion of correctly classified cases with lateral inferior, medial, and superior border involvements was 78% or greater. CONCLUSION: Body involvement can be reliably identified by use of 3-dimensional computed tomography images. Surgeons could reliably and accurately identify superior, medial, and lateral border involvement, which is considered clinically relevant and likely sufficient for the treatment decision process and outcome prognosis. It should be applied by surgeons with a special interest in the shoulder in the framework of clinical routine as well as in research activities.
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Fraturas Ósseas/classificação , Fraturas Ósseas/diagnóstico por imagem , Escápula/lesões , Humanos , Imageamento Tridimensional , Masculino , Prognóstico , Escápula/diagnóstico por imagem , Tomografia Computadorizada por Raios X/métodosRESUMO
BACKGROUND: Fractures of the glenoid frequently require surgical treatment. A comprehensive and reliable scapula classification system involving the glenoid fracture patterns is needed to describe the underlying pathology. The AO Scapula Classification Group introduces an appropriate novel system that is presented along with its inter-rater reliability and accuracy. MATERIALS AND METHODS: An iterative consensus process (involving a series of face-to-face meetings and agreement studies) with an international group of 7 experienced shoulder surgeons was used to specify and evaluate a scapular fracture classification system with a focus on fracture patterns of the glenoid fossa. The last evaluation was conducted on a consecutive collection of 120 scapular fractures documented by both plain radiographs and computed tomography scans including 3-dimensional surface rendering. Inter-rater reliability was analyzed with κ statistics, and accuracy was estimated by latent class modeling. RESULTS: Of 120 scapular fractures, 46 involved the glenoid (38%), with 38 classified as F1 articular rim fractures. The overall median sensitivity and specificity in identifying these fractures were 95% and 93%, respectively. Surgeons' accuracy in classifying F1 fractures ranged from 86% to 100% (median, 94%). Subsequently, classification of simple F1 fractures resulted in a proportion of 36% of anterior rim fractures, 19% of posterior rim fractures, and 45% of short oblique fractures, with accuracies ranging from 85% to 98%. CONCLUSION: This new system for scapular glenoid fractures has proved to be sufficiently reliable and accurate when applied by experienced shoulder surgeons. Further validation of the most detailed system, as well as involvement of surgeons with different levels of training in the framework of clinical routine and research, however, should be considered.
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Fraturas Ósseas/classificação , Escápula/lesões , Humanos , Lesões do OmbroRESUMO
BACKGROUND: Our objective was to utilize a commercially available rodent locked intramedullary nail in a rat femur diaphyseal defect. This model is needed for future studies where materials in the critical defect could be modified with agents to fight infection (antibiotics) or promote osteogenesis. METHODS: After unsatisfactory attempts to develop a reliable femur critical size defect model utilizing various forms of fixation, a locked intramedullary nailing system (AO LockingRatNail) was employed in 105 male Sprague Dawley rats. A 5 mm critical size mid-diaphyseal femoral defect was created using a pneumatic sagittal saw. The intramedullary nail was placed in the femur in a retrograde manner. A prefabricated polymethyl-methacrylate (PMMA) spacer was utilized to fill the defect. Once adequate alignment was achieved, two locking pegs were placed (one distal, one proximal) to provide stable fixation. RESULTS: The technique was successful in 90% of femurs (95 of 105). The majority of complications centered on failure of the placement of locking pegs (7 of 10). One rat presented with migration of the nail out of the knee. Two rats presented with fractures not recognized intraoperatively. These complications occurred early in the study and decreased as surgical experience increased. Surgery was tolerated well by the rats as reflected by significant weight postoperative gain (p < .001). CONCLUSIONS: The AO LockingRatNail is a novel, reproducible, and successful method for stabilization of critical size femoral diaphyseal defects in the rat. This model has future value in the examination of the biological processes involved in the healing of critical bone defects.
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Pinos Ortopédicos , Fraturas do Fêmur/cirurgia , Fêmur/cirurgia , Fixação Intramedular de Fraturas/instrumentação , Fixação Intramedular de Fraturas/métodos , Animais , Antibacterianos/uso terapêutico , Consolidação da Fratura/fisiologia , Masculino , Modelos Animais , Osteogênese/fisiologia , Polimetil Metacrilato , Ratos , Ratos Sprague-Dawley , Infecção da Ferida Cirúrgica/prevenção & controleRESUMO
BACKGROUND: Complications associated with iliac crest bone-graft donor sites have been reported. This prospective study was conducted to determine the prevalence of pain and complications at the iliac crest donor site in patients undergoing treatment of fracture nonunion. METHODS: Ninety-two patients undergoing anterior iliac crest bone-grafting for nonunion or delayed union of a long-bone fracture were prospectively enrolled. Twenty-seven patients undergoing an alternative surgical treatment were enrolled as a control group. Questionnaires including pain on a visual analog scale (0 to 10) at the donor site were completed by patients at two weeks, six weeks, three months, and one year postoperatively. Short Form-36 (SF-36) forms were completed at enrollment and at the time of final follow-up. RESULTS: The mean pain on the visual analog scale at the donor site was 3.9 at two weeks but rapidly decreased to 1.4 at six weeks and reached 0.3 at one year or more postoperatively (p<0.001). Only two patients (2%) reported a pain value of >3 at one year or more postoperatively. There were three deep infections (3%) at the donor site, and no patients had a permanent sensory deficit in the lateral femoral cutaneous nerve distribution. At the time of final follow-up (mean, twenty-two months), scores for the SF-36 bodily pain subscale were significantly higher in the iliac crest group than in the control group, indicating a greater improvement in overall bodily pain in the iliac crest group. CONCLUSIONS: Anterior iliac crest bone-grafting for nonunion was a well-tolerated procedure. Substantial, persistent pain at the iliac crest donor site occurred in 2% of patients. Iliac crest bone-grafting did not appear to impair function or well-being compared with alternative treatments.
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Transplante Ósseo/métodos , Fraturas não Consolidadas/cirurgia , Ílio/transplante , Dor Pós-Operatória/fisiopatologia , Sítio Doador de Transplante/fisiopatologia , Adulto , Idoso , Análise de Variância , Transplante Ósseo/efeitos adversos , Estudos de Casos e Controles , Intervalos de Confiança , Feminino , Seguimentos , Fixação Interna de Fraturas/efeitos adversos , Fixação Interna de Fraturas/métodos , Fraturas Ósseas/diagnóstico por imagem , Fraturas Ósseas/cirurgia , Fraturas não Consolidadas/diagnóstico por imagem , Humanos , Ílio/cirurgia , Masculino , Pessoa de Meia-Idade , Medição da Dor , Dor Pós-Operatória/tratamento farmacológico , Estudos Prospectivos , Radiografia , Procedimentos de Cirurgia Plástica/efeitos adversos , Procedimentos de Cirurgia Plástica/métodos , Medição de Risco , Transplante Autólogo , Resultado do TratamentoRESUMO
A layer of cells (the "biomembrane") has been identified in large segmental defects between bone and surgically placed methacrylate spacers or antibiotic-impregnated cement beads. We hypothesize that this contains a pluripotent stem cell population with potential valuable applications in orthopedic tissue engineering. Objectives using biomembranes harvested from rat segmental defects were to: (1) Culture biomembrane cells in specialized media to direct progenitor cells along bone or cartilage cell differentiation lineages; (2) evaluate harvested biomembranes for mesenchymal stem cell markers, and (3) define relevant gene expression patterns in harvested biomembranes using microarray analysis. Culture in osteogenic media produced mineralized nodules; culture in chondrogenic media produced masses containing chondroitin sulfate/sulfated proteoglycans. Molecular analysis of biomembrane cells versus control periosteum showed significant upregulation of key genes functioning in mesenchymal stem cell differentiation, development, maintenance, and proliferation. Results identified significant upregulation of WNT receptor signaling pathway genes and significant upregulation of BMP signaling pathway genes. Findings confirm that the biomembrane has a pluripotent stem cell population. The ability to heal large bone defects is clinically challenging, and novel tissue engineering uses of the biomembrane hold great promise in treating non-unions, open fractures with large bone loss and/or infections, and defects associated with tumor resection.
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Condrogênese/fisiologia , Consolidação da Fratura/fisiologia , Células-Tronco Mesenquimais/citologia , Osteogênese/fisiologia , Células-Tronco/citologia , Animais , Diferenciação Celular/fisiologia , Masculino , Células-Tronco Mesenquimais/metabolismo , Modelos Animais , Polimetil Metacrilato , Ratos , Ratos Sprague-Dawley , Células-Tronco/metabolismo , Engenharia Tecidual/métodosRESUMO
BACKGROUND: Heterotopic ossification around the elbow can result in pain, loss of motion, and impaired function. We hypothesized that a single dose of radiation therapy could be administered safely and acutely after elbow trauma, could decrease the number of elbows that would require surgical excision of heterotopic ossification, and might improve clinical results. METHODS: A prospective randomized study was conducted at three medical centers. Patients with an intra-articular distal humeral fracture or a fracture-dislocation of the elbow with proximal radial and/or ulnar fractures were enrolled. Patients were randomized to receive either single-fraction radiation therapy of 700 cGy immediately postoperatively (within seventy-two hours) or nothing (the control group). Clinical and radiographic assessment was performed at six weeks, three months, and six months postoperatively. All adverse events and complications were documented prospectively. RESULTS: This study was terminated prior to completion because of an unacceptably high number of adverse events reported in the treatment group. Data were available on forty-five of the forty-eight patients enrolled in this study. When the rate of complications was investigated, a significant difference was detected in the frequency of nonunion between the groups. Of the nine patients who had a nonunion, eight were in the treatment group. The nonunion rate was 38% (eight) of twenty-one patients in the treatment group, which was significantly different from the rate of 4% (one) of twenty-four patients in the control group (p = 0.007). There were no significant differences between the groups with regard to the prevalence of heterotopic ossification, postoperative range of motion, or Mayo Elbow Performance Score noted at the time of study termination. CONCLUSIONS: This study demonstrated that postoperative single-fraction radiation therapy, when used acutely after elbow trauma for prophylaxis against heterotopic ossification, may play a role in increasing the rate of nonunion at the site of the fracture or an olecranon osteotomy. The clinical efficacy of radiation therapy could not be determined on the basis of the sample size. Further research is needed to determine the role of limited-field radiation for prophylaxis against heterotopic ossification after elbow trauma.
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Lesões no Cotovelo , Fraturas Ósseas/cirurgia , Fraturas não Consolidadas/etiologia , Ossificação Heterotópica/radioterapia , Complicações Pós-Operatórias/radioterapia , Adulto , Término Precoce de Ensaios Clínicos , Cotovelo/fisiopatologia , Cotovelo/cirurgia , Feminino , Humanos , Masculino , Pessoa de Meia-Idade , Ossificação Heterotópica/prevenção & controle , Complicações Pós-Operatórias/prevenção & controle , Estudos Prospectivos , Radioterapia/efeitos adversos , Dosagem Radioterapêutica , Amplitude de Movimento Articular , Adulto JovemRESUMO
OBJECTIVES: To determine if cell saver (CS) use in patients with acetabular fractures reduces the volume or rate of allogeneic blood transfused intraoperatively and postoperatively and if this translated to a decrease in blood-related charges to the patient. DESIGN: Retrospective review. SETTING: Level 1 trauma center. PATIENTS: One hundred eighty-six patients with operatively treated acetabular fractures. INTERVENTION: All patients underwent open reduction internal fixation of their acetabular fracture. The decision to use CS was at the surgeon's discretion. MAIN OUTCOME MEASUREMENTS: The volume and rate of intraoperative and postoperative allogeneic blood transfused and blood-related charges were evaluated. RESULTS: CS was used in 60 cases (32%), and the average volume of blood autotransfused was 345 mL. No differences were observed in the rates (58.3% vs 48%, P = 0.1883) or the mean volumes (770 vs 518 mL, P = 0.0537) of intraoperative and postoperative allogeneic blood transfusions between the CS and the non-CS groups. Total blood-related charges in the CS group were significantly higher than that in the nonCS group ($1958 vs $694, P < 0.0001). Subanalyses based on fracture pattern, injury severity score, body mass index, days to surgery, and estimated blood loss were performed. In each subanalyses, no differences were observed in intraoperative and postoperative transfusion rates and volumes, and total blood-related charges were higher in the CS groups. CONCLUSIONS: In the routine use of CS in acetabular surgery, there was no reduction in the volume or rate of allogeneic blood transfused intraoperatively or postoperatively. However, blood-related charges were significantly increased.
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Acetábulo/lesões , Acetábulo/cirurgia , Transfusão de Sangue Autóloga/métodos , Transfusão de Eritrócitos/métodos , Fixação Interna de Fraturas/efeitos adversos , Fraturas Ósseas/terapia , Hemorragia Pós-Operatória/prevenção & controle , Adolescente , Adulto , Idoso , Terapia Combinada , Feminino , Humanos , Cuidados Intraoperatórios/métodos , Masculino , Pessoa de Meia-Idade , Estudos Retrospectivos , Resultado do Tratamento , Adulto JovemRESUMO
Fifty periprosthetic supracondylar femur fractures above a total knee arthroplasty were reviewed. Fractures were closed Lewis and Rorabeck type II with a stable prosthesis. Twenty-nine patients (group I), were treated with locked condylar plating. Twenty-one patients (group II) were treated with nonlocked plating systems or intramedullary fixation. Minimum follow-up was 1.7 years. There were 5 malunions (20%) in group I and 9 (47%) in group II (P < .05). There were no nonunions in group I and 3 (16%) in group II. Complication rates were 12% in group I, compared to 42% in group II. Group I patients had less operative blood loss, healed in better alignment, and had greater knee motion. All 7 patients treated with a retrograde intramedullary nail developed a malunion or nonunion. Locked plating is a reliable treatment for periprosthetic supracondylar femur fractures. We experienced a lower complication, revision, malunion, and nonunion rate with locked plating versus conventional treatment options.
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Artroplastia do Joelho , Placas Ósseas , Fraturas do Fêmur/cirurgia , Idoso , Pinos Ortopédicos , Feminino , Fixação Interna de Fraturas/métodos , Fraturas Mal-Unidas , Fraturas não Consolidadas , Humanos , Masculino , Complicações Pós-Operatórias , ReoperaçãoRESUMO
BACKGROUND: Recent reports have suggested that functional outcomes are similar following either amputation or reconstruction of a severely injured lower extremity. The goal of this study was to compare two-year direct health-care costs and projected lifetime health-care costs associated with these two treatment pathways. METHODS: Two-year health-care costs were estimated for 545 patients with a unilateral limb-threatening lower-extremity injury treated at one of eight level-I trauma centers. Included in the calculation were costs related to (1) the initial hospitalization, (2) all rehospitalizations for acute care related to the limb injury, (3) inpatient rehabilitation, (4) outpatient doctor visits, (5) outpatient physical and occupational therapy, and (6) purchase and maintenance of prosthetic devices. All dollar figures were inflated to constant 2002 dollars with use of the medical service Consumer Price Index. To estimate projected lifetime costs, the number of expected life years was multiplied by an estimate of future annual health-care costs and added to an estimate of future costs associated with the purchase and maintenance of prosthetic devices. RESULTS: When costs associated with rehospitalizations and post-acute care were added to the cost of the initial hospitalization, the two-year costs for reconstruction and amputation were similar. When prosthesis-related costs were added, there was a substantial difference between the two groups ($81,316 for patients treated with reconstruction and $91,106 for patients treated with amputation). The projected lifetime health-care cost for the patients who had undergone amputation was three times higher than that for those treated with reconstruction ($509,275 and $163,282, respectively). CONCLUSIONS: These estimates add support to previous conclusions that efforts to improve the rate of successful reconstructions have merit. Not only is reconstruction a reasonable goal at an experienced level-I trauma center, it results in lower lifetime costs.
Assuntos
Amputação Cirúrgica/economia , Custos de Cuidados de Saúde , Traumatismos da Perna/economia , Traumatismos da Perna/cirurgia , Salvamento de Membro/economia , Salvamento de Membro/métodos , Procedimentos de Cirurgia Plástica/economia , Membros Artificiais/economia , Queimaduras/economia , Queimaduras/cirurgia , Feminino , Humanos , Traumatismos da Perna/reabilitação , Tempo de Internação/estatística & dados numéricos , Masculino , Estudos ProspectivosRESUMO
OBJECTIVE: To compare the mechanical stability of a fixed-angle blade plate with that of a locking plate in a cadaveric proximal humerus fracture-fixation model subjected to cyclic loading. A secondary objective was to evaluate whether the use of synthetic humerus specimens would replicate significant differences found during cadaveric tests. DESIGN: Mechanical evaluation of constructs in bending and torsion. SETTING: Biomechanical laboratory in an academic medical center. METHODS: Simulated humeral neck fractures (Orthopaedic Trauma Association (OTA) classification 11A3), in matched-pair cadaveric and synthetic specimens underwent fixation using either a 3.5-mm, 90-degree cannulated LC-Angled Blade Plate or a 3.5-mm LCP Proximal Humerus Locking Plate. Cadaveric specimen constructs were cyclically loaded in bending and torsion; synthetic specimens were tested in torsion. MAIN OUTCOME MEASURE: Humeral shaft-bending displacements and angular rotations for respective cyclic bending loads and axial torques were recorded and compared at repeated cyclic intervals to evaluate construct loosening. RESULTS: Locking-plate constructs exhibited significantly less loosening than blade-plate constructs for torsional loading in cadaveric specimens (P = 0.036). The two types of constructs performed similarly for torsional loading in synthetic specimens (P = 0.100). Under cyclic, closed-bending load conditions in which the plates served as tension members, both types of constructs performed similarly in cadaveric specimens (P = 0.079). CONCLUSIONS: For simulated humeral neck fractures subjected to cyclic loading, locking-plate constructs demonstrated significantly greater torsional stability and similar bending stability to blade plates in a cadaveric specimen model. In contrast, these same constructs performed similarly with torsional loading when using synthetic humerus specimens. These results indicate potential advantages for locking-plate fixation. They also indicate that the synthetic specimens tested may not be appropriate for evaluating fixation stability in the humeral head, where cancellous bone fixation predominates.
Assuntos
Placas Ósseas , Fixação de Fratura/métodos , Modelos Biológicos , Procedimentos Ortopédicos/métodos , Fraturas do Ombro/cirurgia , Fenômenos Biomecânicos , Cadáver , Desenho de Equipamento , HumanosRESUMO
BACKGROUND: A better understanding of the factors influencing return to work (RTW) after major limb trauma is essential in reducing the high costs associated with these injuries. METHODS: Patients (n = 423) who underwent amputation or reconstruction after limb threatening lower extremity trauma and who were working before the injury were prospectively evaluated at 3, 6, 12, 24, and 84 months. Time to first RTW was assessed. For individuals working at 84 months, the percentage of time limited in performance at work was estimated using the Work Limitations Questionnaire. RESULTS: Estimates of the cumulative proportion returning to work at 3, 6, 12, 24, and 84 months were 0.12, 0.28, 0.42, 0.51, and 0.58. Patients working at 84 months were, on average, limited in their ability to perform the demands of their job 20 to 25% of the time. In the context of a Cox proportional hazards model, differences in RTW outcomes by treatment (amputation versus reconstruction) were not statistically significant. Factors that were significantly associated (p < 0.05) with higher rates of RTW include younger age, being White, higher education, being a nonsmoker, average to high self efficacy, preinjury job tenure, higher job involvement, and no litigation. Early (3 month) assessments of pain and physical functioning were significant predictors of RTW. CONCLUSIONS: Return to work after severe lower extremity trauma remains a challenge. Although the causal pathway from injury to impairment and work disability is complex, this study points to several factors that influence RTW that suggest strategies for intervention.
Assuntos
Emprego/estatística & dados numéricos , Fraturas Ósseas/reabilitação , Traumatismos da Perna/reabilitação , Recuperação de Função Fisiológica , Avaliação da Capacidade de Trabalho , Trabalho , Adolescente , Adulto , Amputação Cirúrgica , Emprego/psicologia , Feminino , Seguimentos , Humanos , Traumatismos da Perna/psicologia , Masculino , Pessoa de Meia-Idade , Procedimentos Ortopédicos , Modelos de Riscos Proporcionais , Estudos Prospectivos , Fatores Socioeconômicos , Centros de TraumatologiaRESUMO
OBJECTIVE: This study was designed to compare mRNA gene expression in healing diaphyseal femoral fractures between those injuries treated with intramedullary nails and those treated with internal plate fixation. DESIGN: RNA gene expression was measured at 1 day, 3 days, and 1, 2, 4, and 6 weeks after surgery in the fracture callus of rats randomized to femoral shaft fracture with intramedullary nail fixation, rigid plate fixation, or sham fracture. SETTING: AAALAC-accredited vivarium of an independent academic medical center. ANIMALS: Fifty-seven, adult, female, Sprague-Dawley rats at 16 weeks of age. INTERVENTION: Femoral fracture with intramedullary nail fixation, femoral fracture with plate and screw fixation, or sham surgery with no fracture. MAIN OUTCOME MEASUREMENTS: RNA expression for 8700 genes was measured with 19 Affymetrix U34A microarrays. The fracture callus was significantly larger with intramedullary nail fixation than with plate fixation. Most genes responded to fracture with a change in mRNA expression. Most of the responding genes followed the same time course for both fixation methods. This included genes related to growth factors, bone matrix, mast cells, most nerve factors, and hematopoiesis. The intramedullary nail group had significantly greater up-regulation for transcripts related to cartilage, cell division, inflammation, and the acetylcholine receptor. There was significantly greater up-regulation in the plate group for genes related to macrophage activity. CONCLUSIONS: There were differentially expressed genes present between the 2 surgical groups that may give insight into the control of fracture repair.