[Appendiceal cancer]. / Rak cherveobraznogo otrostka.

Appendiceal cancer is one of the rarest tumors. In most patients, this disease is diagnosed during appendectomy or after autopsy. The authors report a patient with appendiceal cancer identified during the treatment of appendicular infiltrate and analyze literature devoted to this issue. Clinical case confirms that appendiceal cancer is difficult for differential diagnosis due to peculiarities and variability of its course. This aspect prevents timely treatment of disease. Timely and accurate diagnosis requires not only clinical experience, but also introduction of new technologies and clinical tests that could reduce the risk of damage and increase the accuracy of diagnostic data.

[REPARATIVE OSTEOGENESIS AND ANGIOGENESIS UNDER THE CONDITIONS OF TRANSOSSEOUS OSTEOSYNTHESIS AND THE EXPOSURE TO LOW-INTENSITY LASER RADIATION].

The aim of the study was the morphological analysis of the effect of exposure to low-intensity infrared laser radiation on reparative osteogenesis and angiogenesis in bone regenerate formed during the treatment of fracture under the conditions of transosseous osteosynthesis. In the experiment on rats in control (n=16) and experimental (n=16) groups the fracture of the tibia was modeled, and the reposition and fixation of bone fragments with a device for transosseous osteosynthesis was carried out. In animals of the experimental group, the area of the fracture was exposed to pulsed infrared laser radiation of low intensity. In the group of control animals, similar exposure was imitated. The operated bones were studied using radiography, light and electron microscopy, x-ray electron probe microanalysis. It was found that the sessions of laser irradiation reduced the severity of the inflammatory process, stimulated fibrillogenesis and endovascular capillary growth, accelerated the compaction of the newly formed bone, increased the degree of its maturity, with the fracture healing occurring by primary-type mechanism. Laser therapy of the fracture area provides for the formation of bone regenerate and bone fragment unification at an earlier date.

[Reparative Osteogenesis and Angiogenesis in Low Intensity Electromagnetic Radiation of Ultra-High Frequency].

BACKGROUND: Non-drug correction of reparative bone tissue regeneration in different pathological states - one of the most actual problems of modern medicine. OBJECTIVE: Our aim was to conduct morphological analysis of the influence of electromagnetic radiation of ultra-high frequency and low intensity on reparative osteogenesis and angiogenesis in fracture treatment under transosseous osteosynthesis. METHODS: A controlled nonrandomized study was carried out. In the experiment conducted on rats we modeled tibial fracture with reposition and fixation of the bone fragments both in control and experimental groups. In the animals of the experimental group the fracture zone was exposed to low intensity electromagnetic radiation of ultra-high frequency. Exposure simulation was performed in the control group. The operated bones were examined using radiography, light and electronic microscopy, X-ray electronic probe microanalysis. RESULTS: It has been established that electromagnetic radiation of ultra-high frequency sessions in fracture treatment stimulate secretory activity and degranulation of mast cells, produce microcirculatory bed vascular permeability increase, endotheliocyte migration phenotype expression, provide endovascular endothelial outgrowth formation, activate reparative osteogenesis and angiogenesis while fracture reparation becomes the one of the primary type. The full periosteal, intermediary and intraosteal bone union was defined in 28 days. CONCLUSION: Among the therapeutic benefits of electromagnetic radiation of ultra-high frequency in fracture treatment we can detect mast cell secretorv activity stimulation and endovascular anziozenesis activation.