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2.
Aesthetic Plast Surg ; 46(6): 2938-2946, 2022 12.
Artigo em Inglês | MEDLINE | ID: mdl-36042029

RESUMO

BACKGROUND: Supratip deformity, also known as the pollybeak deformity, accounts for one of the most common iatrogenic deformities requiring revision surgery in rhinoplasty. We aimed to present a novel technique to prevent supratip deformity and increase the tip definition, especially in patients with thick skin. METHODS: A total of eighty-three patients were included in the study. In control group, thirty-three consecutive patients with thick skin underwent structured primary rhinoplasty without any additional maneuvers. In study group, thirty-one consecutive patients with thick skin underwent the same operation with an additional "External supratip suture (ESS)." Nineteen patients with moderate skin were also operated using the ESS to accentuate the supratip break and control the soft tissue response. Patients' supratip regions were analyzed with reference to a tangent line from the tip defining point to the nasion. Two independent blinded plastic surgeons rated the supratip aesthetics on a 5-point scale. RESULTS: The ESS maneuver had better results in the supratip region according to the two parameters which were statistically significant (p < 0.05). No ischemic complications were observed. CONCLUSION: This simple and reliable external approach is a powerful maneuver which can be an effective technique not only in patients with thick skin, but also in moderate skin patients who requires better supratip definition. It enables surgeon to reduce the nasal volume efficiently in patients with noncompliant skin by controlling skin redraping by adhering to Auersvald's hemostatic net principles. We believe that this approach will find a place in the armamentarium of rhinosurgeons. LEVEL OF EVIDENCE IV: This journal requires that authors assign a level of evidence to each article. For a full description of these Evidence-Based Medicine ratings, please refer to the Table of Contents or the online Instructions to Authors   www.springer.com/00266.


Assuntos
Rinoplastia , Humanos
3.
Aesthetic Plast Surg ; 45(2): 628-637, 2021 04.
Artigo em Inglês | MEDLINE | ID: mdl-33037475

RESUMO

BACKGROUND: The posterior cephalic soft triangle is formed between the posterior cephalic border of the lower lateral cartilage, posterior caudal border of the upper lateral cartilage, and the caudal edge of the nasal bone. PCST is an important component of the external nasal valve which provides resistance against dynamic collapse. OBJECTIVES: The objective of this study was to describe the anatomy of the PCST and to demonstrate its anatomic variations, dynamic interplays, and surgical implications. METHODS: A retrospective review was conducted of 310 primary and 42 secondary cases who underwent extended open approach rhinoplasty by the first author. The structures that create the PCST of the nose were preserved unless resection/displacement of them was absolutely necessary. Whenever an external nasal valve pathology was found, it was corrected with one or combination of the following maneuvers: triangular PCST onlay graft, caudal bone outfracture, alar rim graft, lateral crural strut graft. RESULTS: Twenty-four non-consecutive cases were identified in which PCST was intraoperatively confirmed to be weak or deformed. The most common pathology in the PCST was overresection of the posterior segments of the LLC during primary surgery (54.1%), followed by en bloc medialization of the PCST (33.3%). Triangular onlay grafting of the PCST was the most common corrective surgical intervention (83.3%), followed by corrective lateralization of caudal edge of nasal bone (29.1%). External valve function has been restored in 21 (87.5%) cases. CONCLUSIONS: PCST of the nose is an important anatomic landmark which has esthetic and functional significance in rhinoplasty. LEVEL OF EVIDENCE IV: This journal requires that authors assign a level of evidence to each article. For a full description of these Evidence-Based Medicine ratings, please refer to the Table of Contents or the online Instructions to Authors www.springer.com/00266 .


Assuntos
Cartilagens Nasais , Rinoplastia , Estudos de Coortes , Humanos , Cartilagens Nasais/cirurgia , Septo Nasal/cirurgia , Nariz/cirurgia , Estudos Retrospectivos , Resultado do Tratamento
4.
J Craniofac Surg ; 31(3): 796-800, 2020.
Artigo em Inglês | MEDLINE | ID: mdl-31934978

RESUMO

Improvement of the harmony between facial subunits is the ultimate goal of orthognathic surgery and surgeons must accurately make soft tissue projections for planned bony movements. Yet, few studies have examined the effects' of orthognathic surgery on aesthetic parameters of nasolabial area on a thorough basis.This retrospective study included 61 patients that underwent orthognathic surgery. Demographic data, evaluation period, and surgical details were analyzed. Superficial topographical analysis of intercanthal distance, alar width, nasal height, nasal length, nasal tip protrusion, upper lip height, nasal bone angle, supratip break angle, nasal dorsum angle, nasal tip angle, columellar-lobular angle, columellar-labial angle, upper lip angle, and tip-to-midline angle was recorded before and after surgery. Postoperative changes in these parameters and their correlation to maxillary movements were analyzed.Alar width, upper lip height, columellar-labial angle, supratip break angle, nasal dorsum angle, and upper lip angle increased postsurgery, whereas tip-to-midline angle decreased. Upper lip height and columellar-labial angle were significantly correlated with clockwise/counter-clockwise rotation and anterior re-positioning. Columellar-labial angle increased 2° for each 1 mm of anterior movement and decreased 4° for each 1 mm of counter-clockwise rotation. Novel parameters, such as columellar-lobular angle and tip-to-midline angle, were not associated with any maxillary movement postsurgery.Orthognathic surgery primarily affected the lower third of the nose and changed alar width, upper lip height, supratip break angle, nasal dorsum angle, columellar-labial angle, upper lip angle, and tip-to-midline angle in this region; however, only columellar-labial angle and upper lip height were found to be correlated solely with maxillary movements.


Assuntos
Maxila/cirurgia , Nariz/cirurgia , Adolescente , Adulto , Estética , Feminino , Humanos , Lábio/cirurgia , Masculino , Pessoa de Meia-Idade , Osso Nasal/cirurgia , Procedimentos Cirúrgicos Ortognáticos , Estudos Retrospectivos , Adulto Jovem
5.
Aesthet Surg J ; 39(5): 481-494, 2019 04 08.
Artigo em Inglês | MEDLINE | ID: mdl-29394311

RESUMO

BACKGROUND: The junction between upper and lower lateral cartilages, known as "the scroll area," is an important determinant of the spatial relationship between the middle and lower nasal thirds. OBJECTIVES: We offer a graduated and reproducible surgical technique of scroll area management that takes into consideration anatomic, functional, and aesthetic relationships. METHODS: This study was a retrospective review of the recorded intraoperative information to investigate the frequency of the use of scroll reconstruction techniques and perioperative parameters that relate to unintended component alterations in the scroll area. A total of 364 consecutive primary open approach rhinoplasty cases performed by the first author (O.B.) between July 2011 and September 2015 were included in the study. RESULTS: Of the 364 cases who underwent primary open approach rhinoplasty, 329 received some form of scroll reconstruction. Scroll reconstruction was performed in all deviated cases, and 88% of straight noses. The most common technique for scroll reconstruction was overlapping repair (88.3%). As expected, both alar rim and alar crease asymmetries were very frequent in the deviated nose group, 89.4% and 75% respectively. Alar rim and alar crease asymmetries were frequent enough in the straight nose group to deserve special attention, 14.2% and 10.4% respectively. CONCLUSIONS: With careful attention to anatomic details of the scroll area, nasal tip refinements can be performed with predictable safety and accuracy. Our approach is a graduated, reproducible, and individualized way of scroll area management that aims to create the ideal cartilage configuration while preventing unintended component alterations.


Assuntos
Cartilagens Nasais/cirurgia , Rinoplastia/métodos , Adolescente , Adulto , Estética , Feminino , Humanos , Masculino , Pessoa de Meia-Idade , Estudos Retrospectivos
6.
Aesthet Surg J ; 39(1): 29-40, 2019 01 01.
Artigo em Inglês | MEDLINE | ID: mdl-29741560

RESUMO

Background: Congenital, traumatic, or developmental bony vault deformities may require additional interventions rather than classical osteotomies to correct the surface structure or angulations of the nasal bones in rhinoplasty. Objectives: The aim of the study was to determine the effects of the additional osteotomies applied for the correction of the nasal vault asymmetries retrospectively. Methods: Twenty-one patients among 512 primary rhinoplasty cases between 2011 and 2016 with bony vault asymmetries were included in the study. Three patients had bilateral convex, 6 patients had unilateral convex, and 7 patients had unilateral concave surface deformities. Five patients had concave deformity on one side and convex deformity on the other side. Double-layer lateral osteotomies and caudal transverse osteotomies were conducted for the correction of the severe surface anatomy deformities of the nasal bones. The caudal transverse osteotomy was delicately performed with a special osteotome, which was designed to protect inner periosteum and mucosa of the nasal bone, and to prevent uncontrolled fracture formation with thinned edge. Results: Twenty patients (95.2%) had favorable results with restoration of a symmetric bony and cartilaginous nasal vault configuration. None of the bone fragments showed any rotation or malposition. One (4.8%) patient with a crooked nose had suboptimal dorsal geometry without requiring revisional surgery at the level of the cartilaginous nasal vault. Conclusions: The author described the morphology, clinical relevance, and correction methods of the nasal vault and the changes that occur in this area during rhinoplasty in patients with concave, convex, or combined three-dimensional nasal bone deformities. Level of Evidence: 4.


Assuntos
Deformidades Adquiridas Nasais/cirurgia , Osteotomia/métodos , Rinoplastia/métodos , Adolescente , Adulto , Estética , Feminino , Humanos , Imageamento Tridimensional , Masculino , Osso Nasal/anatomia & histologia , Osso Nasal/diagnóstico por imagem , Osso Nasal/cirurgia , Cartilagens Nasais/anatomia & histologia , Cartilagens Nasais/diagnóstico por imagem , Cartilagens Nasais/cirurgia , Satisfação do Paciente , Estudos Retrospectivos , Tomografia Computadorizada por Raios X , Resultado do Tratamento , Adulto Jovem
7.
J Craniofac Surg ; 28(7): 1670-1674, 2017 Oct.
Artigo em Inglês | MEDLINE | ID: mdl-28692498

RESUMO

Fronto-orbital advancement using distraction techniques involves the dura left attached to the osteotomized bone segment to avoid dead space formation and dural injury, whereas it is impossible to reshape the supraorbital bar and the frontal bone complex, when necessary. Our approach combines advantageous parts of conventional and distraction osteogenesis techniques as remodel and distract the supraorbital bar and frontal bone complex as a free bone graft. Twenty-seven patients either being syndromic and nonsyndromic craniosynostosis, with at least 3 years of follow-up were reviewed in this study. Mean age of the patients at the time of the operation was 23.44 ±â€Š18.42 months and mean operative time was 4.96 ±â€Š0.97 hours. Blood transfusion was required in all patients, with an average of 112.04 ±â€Š44.60 mL. Amount of the distraction ranged 10 to 30 mm, a mean of 17.26 ±â€Š4.71 mm for the right side and 18.15 ±â€Š4.69 mm for the left side. Mean duration of consolidation was 98.26 ±â€Š12.98 days and mean follow-up was 41.33 ±â€Š22.92 months. In this study, result of internal distraction of fronto-orbital segment as a nonvascularized bone graft in craniosynostotic patients is reviewed to emphasize the efficacy of the nonvascularized bone graft distraction in management of craniosynostosis. Graft distraction after fronto-orbital and cranial vault remodeling appears to be safe and effective approach in correcting severe craniosynostosis deformities especially necessitating asymmetrical advancement.


Assuntos
Transplante Ósseo/métodos , Craniossinostoses/cirurgia , Osteogênese por Distração/métodos , Pré-Escolar , Seguimentos , Humanos , Lactente
8.
Childs Nerv Syst ; 33(1): 197-199, 2017 Jan.
Artigo em Inglês | MEDLINE | ID: mdl-27526099

RESUMO

Many intracranial as well as extracranial complications can be seen following craniosynostosis surgeries. In this article, we would like to share an extremely rare complication of the infarction of the recurrent artery of Heubner, occurred following frontoorbital advancement. In this case, an 18-month-old male patient underwent supraorbital bar and frontal bone remodeling surgery for nonsyndromic metopic suture synostosis. The preoperative neurosurgical evaluation revealed no signs of increased intracranial pressure. On the 3rd postoperative day, the patient developed asymmetric smile and weakness on the left extremities. Computerized tomography showed a hypodense infarction region around the right basal ganglia and internal capsule, concordant with the region supplied by the recurrent artery of Heubner. The patient's symptoms started to regress on the 2nd day of enoxaparine treatment and he was discharged on 12th postoperative day with almost no signs of the event. In this paper, we presented an unlikely complication after frontoorbital advancement. Keeping in mind the long operating time and the proximity of the procedure to the central nervous system, assessment of the neurological function of the patients both before and after the operation and rapid intervention in case of development of neurologic symptoms are of great importance.


Assuntos
Craniossinostoses/cirurgia , Craniotomia/efeitos adversos , Infarto da Artéria Cerebral Anterior/etiologia , Osso Frontal/cirurgia , Humanos , Lactente , Masculino
9.
Turk J Orthod ; 29(1): 22-26, 2016 Mar.
Artigo em Inglês | MEDLINE | ID: mdl-30112469

RESUMO

A 26-year, 9-month-old woman had chief complaints of mandibular protrusion and facial asymmetry. Extraoral examination indicated mandibular deviation to the left side, severe facial asymmetry, and a concave profile. Because the patient had a vertical maxillary height difference and an occlusal plane cant together with maxillary retrusion, a differential downgraft and advancement surgery with Lefort I osteotomy was planned. To correct the facial asymmetry and mandibular protrusion, concurrent bilateral sagittal split osteotomy was performed. Double-jaw surgical procedures, including maxillary and mandibular movements, are effective in correcting severe facial asymmetry and skeletal Class III malocclusion.

10.
J Craniofac Surg ; 26(1): e68-70, 2015 Jan.
Artigo em Inglês | MEDLINE | ID: mdl-25569423

RESUMO

Complex zygomaticomandibular syngnathia is an extremely rare condition with an unknown etiology. The main goal of the surgery is to release the ankylosis, establish good functioning mandible, and prevent reankylosis, if possible. In our case, we offer a new solution to have an adequate oral opening and to prevent reankylosis. After the release of bony syngnathia, we placed a distractor between mandibular segment and maxillozygomatic complex. To our best knowledge, this is the only syngnathia case in the literature treated using distraction techniques. There is a major improvement in the patient's status. Distraction may broaden our horizons in this rare and difficult-to-treat deformity.


Assuntos
Mandíbula/anormalidades , Maxila/anormalidades , Osteogênese por Distração/métodos , Sinostose/cirurgia , Fissura Palatina/patologia , Feminino , Seguimentos , Gengiva/anormalidades , Gengiva/cirurgia , Humanos , Imageamento Tridimensional/métodos , Recém-Nascido , Fixadores Internos , Mandíbula/cirurgia , Côndilo Mandibular/cirurgia , Maxila/cirurgia , Microstomia/cirurgia , Osteogênese por Distração/instrumentação , Tomografia Computadorizada por Raios X/métodos , Língua/anormalidades , Zigoma/anormalidades , Zigoma/cirurgia
11.
Turk J Pediatr ; 55(4): 447-50, 2013.
Artigo em Inglês | MEDLINE | ID: mdl-24292043

RESUMO

Lymphatic malformations are uncommon, benign and congenital malformations of the lymphatic system exhibiting lack of development of communication between the lymphatic and venous circulation. We report the unusual case of rapidly expanding giant lymphatic malformation of the torso, bilateral axillae and left upper extremity of a newborn. As the first-line treatment, aspiration and sclerotherapy with bleomycin were performed. The sclerotherapy failed to cause regression of the mass, and rapid expansion of the malformation necessitated surgery. Partial resection of the mass was performed. Clinical symptoms of respiratory distress resolved in the early postoperative period, and the patient became hemodynamically stable. However, intrathoracic invasion of the mass developed, leading to restriction of thoracic expansion, ending in death. In conclusion, surgical treatment of giant lymphatic malformations remains challenging.


Assuntos
Neoplasias de Cabeça e Pescoço/diagnóstico , Linfangioma Cístico/diagnóstico , Diagnóstico Diferencial , Neoplasias de Cabeça e Pescoço/congênito , Neoplasias de Cabeça e Pescoço/cirurgia , Humanos , Imageamento Tridimensional , Recém-Nascido , Linfangioma Cístico/congênito , Linfangioma Cístico/cirurgia , Imageamento por Ressonância Magnética , Masculino , Escleroterapia , Tomografia Computadorizada por Raios X
12.
J Craniofac Surg ; 23(3): 780-3, 2012 May.
Artigo em Inglês | MEDLINE | ID: mdl-22565897

RESUMO

Oronasal fistula can cause speech problems, hearing loss, velopharyngeal insufficiency, and social problems related with fetor oris and oronasal fluid leakage. The purpose of this study was to achieve 3-layer closure with autogenous mastoid fascia graft in a group of patients with recalcitrant oronasal fistulas.Sixteen patients, aged between 2 and 56 years (mean, 13.9 y), with recalcitrant palatal fistula were operated on and included into the study in a tertiary clinic. Nine patients had previous fistula repairs. The patients' mean follow-up period was 6.8 months.Fistula closure was obtained in 14 of 16 patients. All 2 failures had type IV + V fistulas according to Pittsburgh Classification. A 3-layer technique for the closure of fistulas with autogenous mastoid fascia graft allows three-dimensional repair of the defect without tension. Using mastoid fascia via postauricular sulcus incision is a good alternative regarding hiding incision scars and not requiring intraoperative repositioning.


Assuntos
Fáscia/transplante , Processo Mastoide/cirurgia , Doenças Nasais/cirurgia , Fístula Bucal/cirurgia , Adolescente , Adulto , Criança , Pré-Escolar , Feminino , Seguimentos , Humanos , Lactente , Masculino , Pessoa de Meia-Idade , Doenças Nasais/complicações , Fístula Bucal/complicações , Resultado do Tratamento
13.
J Oral Maxillofac Surg ; 70(2): e133-40, 2012 Feb.
Artigo em Inglês | MEDLINE | ID: mdl-22260915

RESUMO

PURPOSE: To investigate 1) the changes in pharyngeal airway sizes associated with maxillary distraction osteogenesis and 2) the correlations between maxillary skeletal variables and the pharyngeal airway in adult patients with cleft lip and palate. PATIENTS AND METHODS: The study was carried out in 14 adult subjects with cleft lip and palate. Predistraction records were taken at a mean age of 22.7 ± 4.6 years. All patients had placement of a rigid external distraction device (RED I; KLS Martin, Tuttlingen, Germany) after Le Fort I osteotomy. Lateral cephalograms were assessed before surgery and at short-term follow-up (8.0 ± 6.4 months). The cephalometric skeletal and pharyngeal airway variables were statistically evaluated by use of the Wilcoxon signed-rank test. Spearman ρ correlation was performed to check the correlations between maxillary skeletal and pharyngeal variables. RESULTS: The maxillary movement was 8.7 mm (P < .01). The maxillary depth angle (+7.9°) and effective maxillary length (9.4 mm) increased significantly (P < .01) after distraction, whereas the palatal plane angle remained unchanged. Anterior nasal spine (8.2 mm) and Posterior nasal spine (6.9 mm) moved anteriorly. The overjet increased (9.5 mm) significantly (P < .01). Posterior, superoposterior, and middle airway spaces increased significantly, with mean differences of 7.5 mm, 5.1 mm, and 3.3 mm, respectively. The soft palate moved anteriorly, with the greatest movement at its superior point. Significant positive correlations were observed for the posterior and superoposterior airway spaces and maxillary movement. PNS changes showed the highest correlation with posterior airway changes. CONCLUSIONS: The significant anterior movement of the maxilla resulted in significant increases in posterior, superoposterior, and middle airway spaces. The posterior airway space showed the highest significant positive correlation with the movement of PNS. The posterior and superoposterior airway spaces also showed significant positive correlations with the maxillary skeletal variables.


Assuntos
Fenda Labial/cirurgia , Fissura Palatina/cirurgia , Maxila/cirurgia , Osteogênese por Distração/métodos , Faringe/patologia , Adolescente , Adulto , Cefalometria/métodos , Epiglote/patologia , Fixadores Externos , Feminino , Seguimentos , Humanos , Masculino , Mandíbula/patologia , Maxila/patologia , Osso Nasal/patologia , Osteogênese por Distração/instrumentação , Osteotomia de Le Fort/métodos , Palato/patologia , Palato Mole/patologia , Estudos Retrospectivos , Osso Esfenoide/patologia , Adulto Jovem
15.
Ann Plast Surg ; 67(6): 583-8, 2011 Dec.
Artigo em Inglês | MEDLINE | ID: mdl-22123539

RESUMO

OBJECTIVE: The aim of the study is to investigate the effectiveness of the controlled slow-release granulocyte-monocyte colony-stimulating factor (GM-CSF) system in burn wound healing. MATERIAL AND METHODS: In vivo effect of controlled slow-release GM-CSF from chitosan gel on burn wound healing was evaluated on 18 Wistar-Albino rats, weighing between 250 and 300 g. They were randomly divided into 3 groups; (1) burned only group (n = 6), (2) burned + chitosan group (n = 6), (3) burned + chitosan + GM-CSF group (n = 6). Wound area was measured macroscopically. Hematoxylin and eosin and Masson's trichrome stained sections were evaluated for wound healing and tissue response to the polymer. RESULTS: The best healing process was observed with the controlled slow-release GM-CSF-applied group (group 3) in which the wound area was significantly narrowed. CONCLUSION: The study demonstrated the positive contribution of the single-dose controlled slow-release GM-CSF from chitosan gel on burn wound healing.


Assuntos
Queimaduras/tratamento farmacológico , Quitosana/administração & dosagem , Quitosana/farmacologia , Preparações de Ação Retardada/administração & dosagem , Preparações de Ação Retardada/farmacologia , Géis/administração & dosagem , Géis/farmacologia , Fator Estimulador de Colônias de Granulócitos/administração & dosagem , Fator Estimulador de Colônias de Granulócitos/farmacologia , Cicatrização/efeitos dos fármacos , Animais , Distribuição Aleatória , Ratos , Ratos Wistar
16.
J Craniofac Surg ; 22(4): 1471-5, 2011 Jul.
Artigo em Inglês | MEDLINE | ID: mdl-21772154

RESUMO

The aim of the study was to obtain anatomic bone healing and restoration of the patient's premorbid occlusion in complex facial fractures or comminuted facial fracture. Ten patients who applied to a tertiary health care clinic with complex or comminuted fractures, and mandibular fractures combined with condylar fractures which may impair the occlusal harmony were included in the study.After the preparation of premorbid occlusal splints and direct bonded orthodontic brackets, splint-assisted reduction and internal fixation have been performed. The treatment protocol was completed with 4 to 6 weeks of intermaxillary fixation over the splint. All fracture lines showed complete bone healing, without major complications requiring further treatment. Complications included a minor degree of malocclusion in one of the panfacial fracture patients and slight avascular resorption of the condyle in one of the avulsive open comminuted mandibular fracture patients.Using orthodontic splints and direct bonded brackets to obtain and maintain delicate reduction is an efficacious method for the prevention of occlusal disharmony and aesthetic impairments in comminuted lower facial unit and complicated facial fracture patients.


Assuntos
Ossos Faciais/lesões , Fraturas Cominutivas/cirurgia , Placas Oclusais , Braquetes Ortodônticos , Fraturas Cranianas/cirurgia , Adolescente , Adulto , Idoso , Placas Ósseas , Reabsorção Óssea/etiologia , Parafusos Ósseos , Feminino , Seguimentos , Fixação Interna de Fraturas/instrumentação , Consolidação da Fratura/fisiologia , Fraturas Expostas/cirurgia , Humanos , Técnicas de Fixação da Arcada Osseodentária/instrumentação , Masculino , Má Oclusão/etiologia , Côndilo Mandibular/lesões , Côndilo Mandibular/patologia , Côndilo Mandibular/cirurgia , Doenças Mandibulares/etiologia , Fraturas Mandibulares/cirurgia , Pessoa de Meia-Idade , Complicações Pós-Operatórias , Estudos Prospectivos , Adulto Jovem
18.
Ann Plast Surg ; 67(5): 510-5, 2011 Nov.
Artigo em Inglês | MEDLINE | ID: mdl-21301293

RESUMO

Neural-based flaps are an interesting clinical choice particularly in difficult cases that may not be reconstructed with known techniques. Their popularity is gradually increasing because these flaps offer the advantage of preservation of major extremity arteries and avoidance of microsurgical techniques. Our aim was to explore the feasibility of prefabrication of an osteocutaneous neural island flap model in this study. A peripheral nerve of the rat was implanted into the subcutaneous tissue of a skin flap that was connected to a segment of bone by a soft-tissue bridge, to prefabricate an osteocutaneous flap that was supplied only by the intrinsic vasculature of that nerve after a preliminary delay period. At the end of this study, based on direct observation, microangiographic findings, and additionally, a detailed histologic analysis consisting of both qualitative and quantitative assessments, we have proved that it was possible to prefabricate an osteocutaneous composite flap based on the vascularity of a peripheral nerve after a 2-step delay period. We believe that the clinical application of this new flap will gradually develop based on further experimental studies.


Assuntos
Transplante Ósseo , Transplante de Pele , Retalhos Cirúrgicos/inervação , Animais , Transplante Ósseo/métodos , Modelos Animais , Ratos , Ratos Wistar , Transplante de Pele/métodos
19.
J Craniofac Surg ; 21(5): 1645-7, 2010 Sep.
Artigo em Inglês | MEDLINE | ID: mdl-20856069

RESUMO

Congenital fusion of upper and lower jaw is rare. Only 35 bony syngnathia have been reported up to date, and 9 of them revealed posterior topography. A 10-day-old female infant with facial asymmetry, limited mouth opening, and cardiac murmurs is presented. The radiological findings revealed congenital bony fusion of right coronoid process of the mandible to posterior maxillary region and right palatal shelf agenesis of palatal bone, which seems to be the first case in the literature. Classification systems of bony syngnathia and applied treatment procedures for palatal closure and release of the bony fusion are discussed.


Assuntos
Mandíbula/anormalidades , Maxila/anormalidades , Anormalidades Maxilofaciais/cirurgia , Palato Mole/anormalidades , Zigoma/anormalidades , Anormalidades Múltiplas/cirurgia , Feminino , Humanos , Recém-Nascido , Mandíbula/cirurgia , Maxila/cirurgia , Micrognatismo/cirurgia , Palato Mole/cirurgia , Zigoma/cirurgia
20.
J Craniofac Surg ; 20(6): 2041-8, 2009 Nov.
Artigo em Inglês | MEDLINE | ID: mdl-19881374

RESUMO

OBJECTIVE: : The aim of this study was to develop an internal distractor to release a drug to the distraction site during the distraction process and to investigate whether intermittent bone morphogenetic protein 2 (BMP-2)-containing chitosan hydrogel infusion will improve radiologic and histologic parameters of distraction osteogenesis (DO) when compared with control groups. MATERIALS AND METHODS: : Experimental groups were control group (n = 6), 2-microg single-dose BMP-2-chitosan hydrogel-infused group (n = 6), and 2-microg intermittent BMP-2-containing chitosan hydrogel-infused group (n = 6). In intermittent BMP-infused group, certain amount of BMP-2 loaded chitosan hydrogel injected into the distraction gap for controlled BMP release from the chitosan with every turning of the geared rod of the distractor. Radiologic and histologic evaluation methods have been conducted. CONCLUSION: : The results of the analysis demonstrated that the newly developed distractor effectively stabilized the DO site while allowing intermittent BMP-chitosan infusion. Application of a BMP-2-chitosan hydrogel infusion to the distraction zone facilitates ossification. Intermittent infusion of BMP-2-containing chitosan hydrogel by use of a developed internal distractor increases ossification even more at the site of DO.


Assuntos
Proteína Morfogenética Óssea 2/administração & dosagem , Osteogênese por Distração/instrumentação , Osteogênese/efeitos dos fármacos , Animais , Materiais Biocompatíveis , Quitosana , Portadores de Fármacos , Fêmur/diagnóstico por imagem , Fêmur/cirurgia , Hidrogéis , Infusões Intralesionais , Fixadores Internos , Radiografia , Distribuição Aleatória , Ratos , Ratos Wistar , Fatores de Tempo
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