RESUMO
Severe acute hepatitis is a rare complication of Epstein-Barr virus (EBV) infection. The authors report a case of an 8-month-old male infant who presented with subacute fever and jaundice. The physical examination showed hepatosplenomegaly and ecchymoses on his abdomen, chest wall and extremities. He received vitamin K therapy and prednisolone, and he recovered well without further complications or sequelae. Although severe acute hepatitis is a rare complication of EBV infection, clinicians should recognise this condition in order to provide a prompt treatment.
Assuntos
Infecções por Vírus Epstein-Barr/complicações , Hepatite Viral Humana/etiologia , Herpesvirus Humano 4 , Falência Hepática Aguda/etiologia , Infecções por Vírus Epstein-Barr/tratamento farmacológico , Infecções por Vírus Epstein-Barr/patologia , Infecções por Vírus Epstein-Barr/virologia , Hepatite Viral Humana/tratamento farmacológico , Hepatite Viral Humana/patologia , Hepatite Viral Humana/virologia , Humanos , Lactente , Falência Hepática Aguda/tratamento farmacológico , Falência Hepática Aguda/patologia , Falência Hepática Aguda/virologia , Masculino , Deficiência de Vitamina K/tratamento farmacológico , Deficiência de Vitamina K/etiologiaRESUMO
Cryptococcosis is rare among children, only occurring in about 1% of children with HIV. We report the case of a 12-year-old boy with disseminated cryptococcosis. He had a history of recurrent pneumonia. He then developed meningeal symptoms and was found to have disseminated Cryptococcus neoformans by cerebrospinal fluid and bone marrow aspirate culture. He was treated with amphotericin B for 2 weeks (1 mg/kg/day), and then with fluconazole orally for 8 weeks (12 mg/kg/day). He also received a new diagnosis of HIV and was started on antiretroviral therapy 2 weeks after starting antifungal treatment. At follow-up 8 weeks later, he was doing well.
Assuntos
Infecções Oportunistas Relacionadas com a AIDS/tratamento farmacológico , Antifúngicos/uso terapêutico , Criptococose/tratamento farmacológico , Cryptococcus neoformans , Soropositividade para HIV/complicações , HIV , Anfotericina B/uso terapêutico , Fármacos Anti-HIV/uso terapêutico , Criança , Criptococose/microbiologia , Fluconazol/uso terapêutico , Soropositividade para HIV/tratamento farmacológico , Humanos , MasculinoRESUMO
Spinal tuberculosis (TB) in children is uncommon. The authors report a case of a 3-year-old boy who was diagnosed with TB spondylitis. He presented to the hospital with a back mass, back pain and inability to walk. He failed to receive TB prophylaxis after having been in close contact to his mother who had pulmonary TB. He received incision and drainage and continued on anti-TB regimens without complications. At 4-month follow-up, he was able to stand and walk without assistance. It is important to carry out contact investigations and provide TB prophylaxis to children who have had a history of contacting TB index cases to prevent TB disease and serious complications of TB infection.