Vulvar Reconstruction with Keystone Flaps after Radical Vulvectomy.

Vulvar cancer is a rare oncologic pathology, accounting for only 3%-5% of all gynecologic neoplasms, with squamous cell carcinoma responsible for more than 90% of these cases; the remaining 10% includes Paget disease, lichen sclerosus, and vulvar melanoma. Radical vulvectomy has become the gold standard treatment due to the high recurrence rate and effective local control in patients with squamous cell carcinoma stages IB to IVA. To address these needs, various reconstructive options have been reported in the literature, each potentially offering different results due to their diverse nature. We present a series of patients who underwent vulvar reconstruction with the keystone flap, describing the surgical technique, complication rate, advantages over other techniques, and long-term follow-up.

Chronic follicular pancreatitis: a space occupying lesion with spontaneous resolution.

Follicular pancreatitis (FP) is an extremely odd entity characterized by the presence of a pseudotumor that histologically presents lymphoid aggregates and germinal centers. The authors present the case of a 67-year-old woman with epigastric pain and jaundice. Endoscopic ultrasonography (EUS) was performed, revealing a 14x15 mm hypoechoic area with irregular edges in the head of the pancreas. The in situ cytological study showed polymorphic lymphoid cellularity, without atypia suggesting neoplasia. The cell block and the immunohistochemical study showed a polyclonal population with a pattern suggestive of FP. The patient presented spontaneous clinical improvement. The EUS follow up three months later shown pancreatic parenchyma with homogeneous echogenicity and no space occupying lesions were indentified. Since the diagnosis of FP has been reached after surgery in most cases, the treatment is not well established. However, no recurrences have been reported after surgery and spontaneous resolution has been observed in incomplete resections, which suggests the indication for conservative management. Diagnostic EUS has a fundamental role in the differential diagnosis between FP and pancreatic neoplasms, two entities with very different prognosis, and makes it possible to avoid, in the case of FP, unnecessary surgeries with the associated morbidity and mortality.

Jejunal varix with a high transfusion requirement: therapy with cyanoacrylate with radiological control by double-balloon enteroscopy.

A jejunal varix with high transfusion requirement is treated by double-balloon enteroscopy with cyanoacrylate/ lipiodol with radiological control. The patient had not gastrointestinal hemorrhage or transfusion requeriment after 8 months follow up. Our recent previous article in Rev Esp Enferm Dig on advanced therapeutics by enteroscopy is referenced, providing this new therapeutic possibility.

Surgical approach to uterine myomatosis in patients with infertility: open, laparoscopic, and robotic surgery; results according to the quantity of fibroids.

OBJECTIVE: To compare approaches to myomectomy (laparotomic, laparoscopic, and robotic). To show the relationship between the number of fibroids and the reproduction diagnosis. METHODS: Observational, analytical, retrospective, and cross-sectional study; where the surgical approach used, was evaluated in terms of surgical bleeding, time, number and weight of fibroids and reproductive results. RESULTS: 69 patients were treated through different approaches and divided into 3 groups. The differences found among groups were in favor of laparotomic myomectomy in terms of the number (p=0.000) and weight of fibroids (p=0.004). Robotic surgery was also longer (p=0.000). In the analysis of the influence of the number of fibroids to achieve pregnancy, the result was in favor of the minimally invasive routes, after surgery, both in the group of < 6 fibroids (p=0.017), and that of > 6 fibroids (p=0.001), without differences in the time from surgery to pregnancy (p=0.979). CONCLUSIONS: The surgical approach decision should consider the number and size of resected fibroids, surgical time, and reproductive diagnosis. The minimally invasive route should be offered whenever possible due to its better outcome on achieving pregnancy, without forgetting the benefits of laparotomy, while also accrediting the recently introduced robotic-assisted approach.

Serum estradiol level on the day of trigger as a predictor of number of metaphase II oocytes from IVF antagonist cycles and subsequent impact on pregnancy rates.

OBJECTIVE: This study aimed to examine the association between serum estradiol levels and number of metaphase II oocytes harvested after in vitro fertilization cycles used in embryo transfers and the subsequent impact on pregnancy rates. METHODS: This observational analytical retrospective study was carried out in 2010-2018 at the Angeles del Pedregal Hospital. It included 181 cases and looked into the number of metaphase II oocytes to predict pregnancy rates. Statistical analysis was based on the calculation of correlations between variables and logistic regressions. RESULTS: Estradiol levels increased with the number of oocytes by a median correlation (r=0.482, p=0.000). On the day of trigger, estradiol levels predicted the number of retrieved oocytes with 23% reliability (R2=0.232, p=0.000); a linear trend correlation of r=0.489, p=0.000 was found between estradiol levels on the day of trigger and number of metaphase II oocytes. CONCLUSIONS: Serum estradiol on the day of trigger as a predictor of metaphase II oocytes in antagonist cycles encourages greater oocyte maturity and fertilization, whereas, in isolation, it does not determine the pregnancy achievement.

Prevalencia de hormona antimülleriana en mujeres latinas atendidas en un centro de fertilidad en México / Antimüllerian hormone prevalence in Latin women treated at a fertility center in Mexico

Resumen Antecedentes: La hormona antimüllleriana (HAM) ha sido utilizada como marcador de reserva ovárica, lo cual ayuda a predecir el éxito. Se desconoce si valores de otros países son apicables a México. Objetivo: Determinar los valores de HAM en nuestra población para graficarlas acorde a grupos de edad y evaluar su comportamiento. Metodología: Estudio observacional, descriptivo, retrospectivo y transversal de pacientes del 2008 al 2018, con reporte de nivel de HAM excluyendo a pacientes con enfermedades que alteran su nivel, analizando por grupos de edad en un laboratorio. Resultados: 450 pacientes de 36.93 años, el rango del valor de la HAM fue desde 0.003 ng/ml hasta 9.4 ng/ml, con una media de 1.5, con una disminución anual a partir de los 40 años (0.1-0.3). Correlación de Spearman de -436 (p < 0.000) con una asociación leve entre la edad y el nivel de HAM, pero sí lineal (p < 0.000). Conclusiones: La HAM es útil y sirve para dar recomendaciones personalizadas, así como base de estudios epidemiológicos en pro de una medicina individualizada.

Abstract Background: Antimüllerian hormone (AMH) has been used as a marker of ovarian reserve, which helps predict success. It is unknown if values from other countries are applicable to Mexico. Objective: To determine the AMH values in our population to graph them according to age groups and evaluate their behavior. Methodology: Observational, descriptive, retrospective, and cross-sectional study of patients from 2008 to 2018, with a AMH level report excluding patients with diseases that alter their level, analyzing by age groups in a laboratory. Results: 450 patients of 36.93 years old, the range of the AMH value was from 0.003 ng/ml to 9.4 ng/ml, with a mean of 1.5, with an annual decrease from 40 years of age (0.1-0.3). Spearman's correlation of -436 (p < 0.000) with a slight association between age and AMH level, but it was linear (p < 0.000). Conclusions: AMH is useful and serves to give personalized recommendations, as well as basis of epidemiological studies in favor of an individualized medicine.

Factores de riesgo cardiovascular y renal, y perfil socioeconómico en individuos de la etnia wichi de "el impenetrable", chaco, argentina / Cardiovascular and renal risk factors and socioeconomics profile in individuals of the wichi ethnia group from "el impenetrable", chaco, argentina

Resumen Introducción: Varios estudios han demostrado en poblaciones indígenas alta prevalencia de obesidad, diabetes mellitus, hipertensión arterial, proteinuria y enfermedad renal crónica. Objetivo: Detectar factores de riesgo cardiovascular y renal, hipertensión arterial, sobrepeso y obesidad, obesidad central, diabetes y proteinuria, y evaluar nivel educativo, situación laboral, nivel socioeconómico y cobertura de salud en sujetos de la etnia wichi, habitantes de "El Impenetrable" chaqueño. Material y métodos: Se realizó un estudio descriptivo observacional, de corte transversal, con muestra aleatoria de sujetos mayores de 18 años. La encuesta semiestructurada, y traducida a lengua wichi, incluyó: edad, sexo, sedentarismo, tabaquismo, nivel educativo, situación laboral, cobertura de salud y nivel socioeconómico. Se midió peso, talla, circunferencia de cintura, presión arterial sistólica y diastólica, glucemia y proteinuria. Se calculó el índice de masa corporal. Resultados: Se evaluaron 156 personas (el 58,3% varones, edad 34 ± 12 años). El índice de masa corporal fue de 27,9 ± 5,3, sin diferencia entre sexos. Presentó hipertensión arterial el 10,8%, sobrepeso el 34,0%, obesidad el 30,9%, obesidad central el 40,1% (mayor en mujeres, p= 0,03), tabaquismo el 17,4%, sedentarismo el 83,3%, y proteinuria el 14,5%. Se registró un único caso de diabetes. Solo 6,4% refirió trabajar, el 49,3% no había finalizado estudios primarios, el 61,7% calificó como marginal en el nivel socioeconómico, y solo el 3,8% tenía cobertura de salud. Conclusión: Este grupo poblacional evidencia un alto grado de vulnerabilidad alimentaria, educativa, laboral, social y sanitaria, reflejado en la alta prevalencia de factores de riesgo cardiovascular y renal (en particular exceso de peso y obesidad central), en el bajo nivel educativo, laboral y socioeconómico, y en la falta de cobertura de salud.

Abstract Introduction: Several studies have shown a high prevalence of obesity, diabetes mellitus, hypertension, proteinuria and chronic kidney disease in indigenous populations. Aim: To detect cardiovascular and renal risk factors, hypertension, overweight and obesity, truncal obesity, diabetes and proteinuria, and to evaluate educational level, employment situation, socioeconomic level and health care coverage in subjects from the Wichi ethnic group who inhabit in "El Impenetrable" in Chaco. Methods: An observational, descriptive, cross-sectional study was carried out, with a random sample of subjects over 18 years of age. The semi-structured survey, translated into the Wichi language, included: age, sex, sedentary lifestyle, smoking habit, educational level, employment situation, health care coverage and socioeconomic level. Weight, height, waist circumference, systolic and diastolic blood pressure, blood glucose and proteinuria were measured. Body mass index was calculated. Results: 156 people were evaluated (58.3% men; age: 34 ± 12 years). The body mass index was 27.9 ± 5.3, with no difference between the sexes. Hypertension was present in 10.8% of individuals; overweight in 34.0%; obesity in 30.9%; truncal obesity in 40.1% (higher in women, p = 0.03); smoking habit in 17.4%; sedentary lifestyle in 83.3%, and proteinuria in 14.5%. A single case of diabetes was registered. Only 6.4% reported having a job, 49.3% had not completed primary studies, 61.7% qualified as marginal in terms of socioeconomic status, and only 3.8% had health care coverage. Conclusion: This population group shows a high degree of food, educational, occupational, social and health vulnerability, reflected in the high prevalence of cardiovascular and renal risk factors (particularly excess weight and truncal obesity), in the low educational, employment and socioeconomic levels, and in the lack of health coverage.

Evaluación de la calidad en el desempeño de la Clínica de Colposcopia del Hospital Militar de Especialidades de la Mujer y Neonatología / Evaluation of quality in the performance of the Colposcopy Clinic of the Hospital Militar de Especialidades de la Mujer y Neonatología

Resumen OBJETIVO: Evaluar la calidad del desempeño de la Clínica de Colposcopia del Hospital Militar de Especialidades de la Mujer y Neonatología, mediante indicadores establecidos, en el periodo 2008-2014 versus 2015 después de la implementación de acciones de mejora. MATERIALES Y MÉTODOS: Estudio observacional, descriptivo, transversal y retrospectivo efectuado en el Hospital Militar de Especialidades de la Mujer y Neonatología en dos periodos (2008-2014 y 2015) en la clínica de Colposcopia. Para la selección de la muestra se utilizó un cálculo no probabilístico de conveniencia. Para el análisis de los datos se utilizó el mapa de ubicación MEDICSUS®. Los resultados se analizaron con el programa Microsoft Excel©; se utilizó estadística descriptiva. RESULTADOS: En el periodo 2008-2014 se analizaron 337 expedientes, con 22 indicadores de calidad, de los que 18 cumplieron en su totalidad. Para la comparación del periodo 2015 se evaluaron los 6 indicadores mínimos, enfocados en la valoración de lesiones de alto grado e invasoras, resultando en una calificación final de 88% mediante el mismo índice ("desempeño sobresaliente"). CONCLUSIONES: La medición de indicadores de calidad mejora el nivel de atención médica y refuerza las políticas de tratamiento en las instituciones de salud. Este tipo de estudios son decisivos para cumplir con las metas propuestas por las organizaciones de salud nacionales e internacionales.

Abstract OBJECTIVE: To evaluate the quality in the performance of the colposcopy clinic, of the "Hospital Militar de Especialidades de la Mujer y Neonatología" using quality indicators, through 2008-2014 and then comparing results with the year 2015. MATERIALS AND METHODOS: Descriptive, observational, cross-sectional retrospective study, held at the Hospital MiIitar de Especialidades de la Mujer y Neonatología in 2008-2014. Medical records of patients that had medical attention at the clinic were analyzed, using a non-probabilistic sample, without age limit and the MEDICSUS© methodology. The results will be analyzed with the Microsoft Excel© program; Be a descriptive statistic. RESULTS: In the 2008-2014 period, 337 files were analyzed, with 22 quality indicators, of which 18 were completed. For the comparison of the 2015 period, the 6 minimum indicators were evaluated, focused on the assessment of high-grade and invasive injuries, resulting in a final rating of 88% through the same index ("outstanding performance"). CONCLUSIONS: Measurement of quality indicators has improved the quality in medical care, and has improved institutional performance. These studies are key to meet the goals proposed by national and international health organizations.

Situación nutricional y factores de riesgo cardiovascular y renal en relación al peso al nacer. Factores de riesgo en Pediatría / Nutritional status and cardiovascular and renal risk factors related to birth weight in children from Gran Resistencia, Chaco, Argentina. Risk factors in Pediatrics

INTRODUCCIÓN: Se carece de datos sobre situación nutricional y factores de riesgo cardiovascular y renal en pediatría en la provincia del Chaco, una de las más pobres y con mayor población pediátrica de Argentina. OBJETIVO: Determinar la prevalencia de factores de riesgo nutricionales (bajo peso/talla, baja talla/edad, bajo peso y sobrepeso), factores de riesgo perinatales (edad materna y edad gestacional al nacimiento), cardiovasculares y renales (sobrepeso, hipertensión arterial y proteinuria), correlacionados con el peso al nacer, en población de un mes a 18 años del conglomerado urbano del Gran Resistencia, provincia del Chaco. MATERIAL Y MÉTODOS: Se realizó un estudio descriptivo observacional de corte transversal. Los participantes se seleccionaron por muestreo probabilístico por conglomerados según peso de la población en cada estrato, de escuelas para niños de 6 a 18 años y de centros de salud para menores de 6.RESULTADOS: Se estudiaron 850 niños. La prevalencia de factores de riesgo fue: 24% alto riesgo por edad materna; 21% nacidos pre-término; 7,2% bajo peso al nacer; 9,1% baja talla/edad; 4,2% bajo peso/talla; 11,8% alto peso/talla; 6,3% bajo peso/edad; 2,4% proteinuria; y 6,8% hipertensión arterial. En menores de 6 años con bajo peso al nacer comparados con nacidos con peso normal, la odd ratio para presentar bajo peso/talla fue de 6,15, y para bajo peso/edad de 5,02; para nacidos con alto peso comparados con nacidos con peso normal, la odd ratio para sobrepeso fue 3,07. CONCLUSIONES: La población pediátrica estudiada presenta una situación de alto riesgo nutricional que correlaciona con el peso al nacer. La prevalencia de proteinuria e hipertensión arterial no se asociaron al peso al nacer

INTRODUCTION: There is a lack of data on nutritional status and cardiovascular and renal risk factors in pediatrics in the province of Chaco, one of the poorest provinces and with the largest pediatric population in Argentina. OBJECTIVE: To determine the prevalence of these risk factors: nutritional (low weight/height, low height/age, low weight and overweight); perinatal (maternal age and gestational age at birth), as well as cardiovascular and renal (overweight, hypertension and proteinuria), correlated with birth weight, in population from one month old to 18 years old in the urban agglomeration of Gran Resistencia, province of Chaco. MATERIAL AND METHODS: An observational descriptive cross-sectional study was conducted. Participants were selected by probabilistic sampling through agglomerations according to population weight in each strata, taken from schools for 6-18 year-old children and from health centers for children under 6. RESULTS: A total of 850 children were studied. The prevalence of risk factors was: 24% with high risk for maternal age, 21% with preterm birth, 7.2% with low birth weight, 9.1% with low height/age, 4.2% with low weight/height, 11.8% with high weight/height, 6.3% with low weight/age, 2.4% with proteinuria and 6.8% with high blood pressure. In children under 6 years of age with low birth weight, compared to those with normal birth weight, the odd ratio for low weight/height was 6.15, and for low weight/age it was 5.02; for those born with a high weight compared to those born with normal weight, the odd ratio for overweight was 3.07. CONCLUSIONS: the pediatric population which was studied presents a situation of high nutritional risk that correlates with birth weight. The prevalence of proteinuria and high blood pressure were not associated with birth weight

Supervivencia a 5 años postratamiento de cáncer de mama: experiencia institucional / Breast cancer survival after 5 years of treatment: Institutional experience

Resumen OBJETIVO: Determinar la supervivencia a 5 años (global y libre de enfermedad) y su relación con las variables: recurrencia, etapa clínica, tipo y grado histológicos, tamaño del tumor, invasión ganglionar axilar e inmunohistoquímica. MATERIALES Y MÉTODOS: Estudio observacional, descriptivo y retrospectivo efec-tuado en pacientes con cáncer de mama atendidas en 2010 en el Hospital Militar de la Mujer, Ciudad de México, confirmado por histopatología. La supervivencia global y libre de enfermedad a cinco años se estableció a partir del tiempo trascurrido desde el diagnóstico hasta la ocurrencia de un evento (recidiva, metástasis o muerte) o fecha del último contacto, con límite a diciembre de 2015. RESULTADOS: Se analizaron 197 expedientes pero se descartaron 78: por repetición de casos (49), por falta de información (21), y debido a recurrencias de años previos (8). Los límites de edad fueron 30 y 84 años, con media de 56.2 años. Los casos en etapa temprana (hasta EC IIA) representaron 40%, la supervivencia global fue de 81% a 5 años. En las pacientes con recurrencias las probabilidades de supervivencia fue-ron de 51%; las pacientes en etapas avanzadas tuvieron menores probabilidades de supervivir. No fue posible demostrar asociación estadísticamente significativa entre el tamaño del tumor, tipo y grado histológico, inmunohistoquímica e invasión ganglionar y la supervivencia. CONCLUSIONES: El estudio demuestra que las pacientes en etapas avanzadas tienen menores probabilidades de supervivir, por lo que es imperativo que se continúen esfuer-zos en promoción de la salud hasta conseguir que la detección sea en etapas curables.

Abstract OBJECTIVE: To determine 5-year survival (global and disease-free) and its relationship with variables: recurrence, clinical stage, histological type and grade, tumoral size, axillary lymph node invasion and immunohistochemistry. MATERIALS AND METHODS: Observational, descriptive and retrospective study carried out in patients with breast cancer attended in 2010 at the Hospital Militar de la Mujer, in Mexico City, confirmed by histopathology. The overall survival and disease-free to five years has been established from the time elapsed since the diagnosis until the occurrence of an event (recurrence, metastasis or death) or date of the last contact, with a limit of December 2015. RESULTS: 197 records were analysed; however 78 were discarded either: by repetition of cases (49), due to lack of information (21) and due to recurrences from previous years (8). The age range were 30 and 84 years, with an average of 56.2 years. The cases in early stage (CS IIA) was 40%, and overall survival 81% at 5 years. In the patients with recurrences the probabilities of survival were 51%; and the patients in advanced stages were less likely to survive. It was not possible demonstrate of statistically significant association between tumoral size, type and histological grade, immunohistochemistry and lymph node invasion and survival. CONCLUSIONS: The study shows that patients in the update stages have less likely to survive, so it is imperative that efforts continue in health promotion until getting the detection in curable stages.

Determinación del tamaño y volumen renal en recién nacidos considerados normales según criterios de la OMS mediante ecografía. Estudio descriptivo, observacional y transversal con revisión de la bibliografía / Determination of renal length and volume through ultrasound scanning in newborn infants considered normal according to WHO criteria. A descriptive, observational, cross-sectional study and literature review

INTRODUCCIÓN: La masa renal y el número de glomérulos se correlacionan significativamente en niños menores de tres meses así como en adultos normales, pero ambos solo son medibles "ex vivo". Por otro lado, el volumen renal (VR), también proporcional a la masa renal, puede ser obtenido por ecografía, como un sustituto para la estimación del número de glomérulos "in vivo". El VR se calcula mediante una fórmula que incluye la medición de tres diámetros renales: longitudinal (DL), antero-posterior (DAP) y transverso (DT). OBJETIVOS:Determinar los diámetros DT, DL, DAP y el volumen renal; y establecer la relación de estos diámetros con las medidas antropométricas en neonatos (dentro de las 48 hs. de nacidos), considerados normales según criterios de la OMS, de la ciudad de Resistencia, provincia del Chaco, República Argentina. MATERIAL Y MÉTODOS: Se realizó un estudio descriptivo observacional, de corte transversal, con muestreo no probabilístico de 27 neonatos de ambos sexos definidos como sanos tanto en las condiciones perinatales como del neonato. Los estudios ecográficos fueron realizados por un solo especialista en diagnóstico por imágenes, estando aún internados la madre y el recién nacido (RN). RESULTADOS: El DL fue de 48,3 y 48,1 mm para el RD y para el RI respectivamente. El volumen renal total (VRT) fue de 23,3 ± 4,8 ml. Las medias halladas fueron 4,2 cm x 2,3 cm x 2,2 cm. Sólo en el DT (tanto en RI y RD) se encontró correlación con peso, talla y superficie corporal (SC) (p < 0,01). CONCLUSIONES: Los diámetros y el VR determinados se encuentran en un rango intermedio a los descritos en la bibliografía. El DT se correlacionó con peso, talla y SC. La forma de los riñones de neonatos es diferente a la de riñones de niños mayores o adultos, debiéndose comprobar si para este grupo etáreo se debe adoptar otra fórmula, la del cilindro elíptico en lugar de la fórmula del elipsoide o de Dinkel

INTRODUCTION: Renal mass and glomerular number correlate significantly in infants under the age of 3 months and in normal adults, but both of them can only be measured ex vivo. On the other hand, renal volume (RV), also proportional to renal mass, can be calculated through ultrasound scanning, an alternative to estimate glomerular number in vivo. Renal volume is determined by means of a formula which includes three diameter measurements: longitudinal (LD), anteroposterior (APD) and transverse (TD). OBJETIVES: To determine TD, LD, APD and renal volume, and to establish the relation between these diameters and anthropometric measurements in neonates (within the first 48 hours after birth), considered to be normal according to WHO criteria. The study was performed in the city of Resistencia, province of Chaco, Argentina. METHODS: A descriptive, observational, cross-sectional, non-probability sampling study was conducted on 27 male and female neonates, who were healthy during the perinatal and neonatal periods. Ultrasound scanning was performed by an imaging expert while both the mother and the newborn infant (NI) were still hospitalized. RESULTS: The LD was 48.3 mm in the right kidney (RK) and 48.1 mm in the left kidney (LK). The total renal volume (TRV) was 23.3 ± 4.8 mL. The mean kidney measurements were 4.2 cm x 2.3 cm x 2.2 cm. A correlation with weight, height and body surface area (BSA) was found only in the TD of both kidneys (p < 0.01). CONCLUSIONS: The diameters and the RV values measured during the study are within the ranges described in the reviewed literature. The TD was correlated with weight, height and BSA. The shape of neonates' kidneys is different than that of older children and adults, suggesting that another formula, such as the elliptic cylinder equation instead of the ellipsoid or Dinkel's formula, should be used for this age group

Not all carboxylates are created equal: differences in interaction of carboxylated peptides with a CaCO3 dimer.

The carboxylate group has been considered the "glue" for mineralizing proteins because of its ability to bind Ca(II). We propose the calcium salts of dicarboxylated dipeptides (Asp-Asp and Glu-Glu) as the smallest models of a mineralizing protein active site. Molecular dynamics/simulated annealing was used for conformational search of the dipeptide global minimum. Semiempirical blind docking was used for configurational search of all cluster-peptide complexes and structures were then optimized in the gas phase at the RI-MP2/SVP level of theory. Solvent effects were also taken into account. We found that the energy of interaction of the calcium carboxylates with a calcium carbonate dimer can be either favorable or unfavorable depending on side-chain length, so side-chain carboxylic groups belonging to different amino acids may show different affinities towards calcium carbonate.

Educación para la salud comunitaria: alertando sobre enfermedades crónicas no transmisibles a través de la extensiónuniversitaria de la facultad de medicina, UNNE / Community Health Education: warning about CNCDs through the extension university faculty of medicine, UNNE

Introducción: El extensionismo permite crear vínculos entre la Universidad y la Sociedad. Los objetivos de este trabajo fueron promover la educaciòn para la salud sobre ECNT mediante la realización de un proyecto de extensión universitaria en el cual se obtuvieron la frecuencia de obesidad (OB), obesidad central (OC), presión arterial (PA) y glucemia en transeúntes caucásicos de la ciudad de Resistencia, Chaco y alerta a la población sobre la implicancia de los mismos en el estado de salud a largo plazo. Materiales y métodos: Participaron 418 estudiantes que evaluaron a 3034 transeúntes en 5 plazas conmemorando el Día Mundial del Riñón. Es un estudio observacional, de coret transversal, con muestra no aleatoria. Los puntos de corte de las variables fueron los de la OMS y del VII JCH. Resultados: 642(21,2 por ciento) transeúntes fueron obesos, 1041(34,3 por ciento) hipertensos y 1161(38,2 por ciento) con OC. El sexo masculino desde la cuarta década presentó mayor prevalencia de FR que el sexo femenino. Sin embargo la OC fue más frecuente en las mujeres. Las 1510 glucemias encontraron un coeficiente de correlación con el IMC de 0,78. Difusión: Los valores hallados son semejantes a la Encuesta Nacional de Factores de Riesgo 2009. Conclusión: Este trabajo permitió alertar a la población sobre ECNT y formar a estudiantes en su detección, análisis e interpretación de los datos obtenidos...

Abstract: Introduction: The extensionism creates links between the University and the society. The objectives of this study were to promote health education on NCDs by conducting a university extension project in which the frequency of obesity(OB), central obesity(CO), blood pressure(BP) and glucose were obtained in caucasian passers of the city of Resistencia, Chaco and alert the public about the implications of them in the long-tem health. 418 students participated evaluating 3034 passers of 5 squares commemorating World Kidney Day. Materials and method: This is an observational, cross-sectional, non-random sample study. The breakpoints of the variables were those published by WHO and VII JCH. Result: 642(21,2 percent) passers were obese, 1041(34,3 percent) hypertensive and 1161(38,2 percent) witg OC. The male sex from the fourth decade had higher prevalence of cardiovascular risk factors tham female sex. However, the OC was more frequent in women. The glycemic control of 1510 found a Pearson correlation coefficient of 0,78 with BMI. Discussion: The values found are similar to the National Survery of Risk Factors 2009. Conclusion: This work allowed warming people about NCDs and train students in the detection, analysis and interpretation of data...

Factores de aterogenicidad y angiopatía en la diabetes mellitus tipo 2 de región andina

En la diabetes mellitus (DM) tipo 2 múltiples factores de riesgo general (ej. sexo, obesidad, dislipidemia, nefropatía progresiva, etc) son determinantes de la acelerada y severa aterosclerosis, con elevada morbilidad y prematura mortalidad. Estos factores fueron evaluados protocolizados transversalmente en 5 años a 258 pacientes con DM tipo 2 de la región andina (Quito 2815 m/snm).

Genetic variability and differentiation between populations of Rhodnius prolixus and R. pallescens, vectors of Chagas' disease in Colombia

Enzyme polymorphism in Rhodnius prolixus and R. pallescens (Hemiptera, Reduviidae), principal vectors of Chagas' disease in Colombia, was analyzed using starch gel electrophoresis. Three geographic locations were sampled in order to determine gene flow between populations and to characterize intra- and interspecific differences. Of 25 enzymes assayed 10 were successfully resolved and then used to score the genetic variation. The enzymes PEPD, GPI, PGM and ICD were useful to differentiate these species and PGD, PGM and MDH distinguished between sylvatic and domiciliary populations of R. prolixus. Both polymorphism and heterozygosity indicated greater genetic variability in sylvatic habitats (H = 0.021) compared to domiciliary habitats (H = 0.006) in both species. Gene flow between sylvatic and domiciliary populations in R. prolixus was found to be minimal. This fact and the genetic distance between them suggest a process of genetic isolation in the domiciliary population.

Cuadriplejia y embarazo: reporte de un caso / Quadriplejia and pregnancy: report of a case

Se presenta el primer caso de Cuandriplejia y Embarazo en nuestra Institución, se revisa la literatura sobre el tema haciendo énfasis en el Síndrome de Disreflexia Autonómica