Alternative therapies for Covid-19.

Recently, the outbreak of COVID-19 caused serious global health issues and the world is facing a crisis of antiviral resistance. To overcome the crisis, we reviewed the existing therapies that could be an alternative and effective treatment for COVID-19. Therapies such as ozone, laser, UV radiation and radiation therapy are discussed and the mechanism of killing is elaborated. In conclusion, the ozone, laser and radiation therapy could be considered as an alternative therapy in extirpating the coronavirus from bloodstreams and the challenges in bringing these therapies to clinical trials.

Failures of the RM finger prosthesis joint replacement system.

In our unit a high failure rate of the RM finger prosthesis joint replacement system was noted, prompting a review of cases. A series of patients underwent implantation under the care of one surgeon and the results were monitored. Twenty-one devices were implanted of which 16 were inserted for rheumatoid disease. Patients were reviewed regularly and the implant performance was assessed critically along with survival of the implant to revision, infection or death of the patient. The mean follow-up was 32 months. Unacceptable failure rates at early and medium term stages were identified, with 15 of the implants revised by 2 years. Loosening was the commonest mode of failure. The authors do not recommend the use of this implant, especially in cases of rheumatoid arthritis.