RESUMO
Abstract Tinea faciei is a relatively uncommon dermatophyte infection entailing atypical clinical symptoms, usually misdiagnosed and treated with corticosteroids. The authors describe a case of tinea faciei on the right eyebrow caused by Trichophyton interdigitale. The patient was an 18-year-old girl, who had an inflammatory plaque with a scaly, pustular surface on the right eyebrow and upper eyelid, which had persisted for over 1 month. She was once misdiagnosed as having eczema and was treated using corticosteroid cream. A diagnosis of tinea faciei was made based on direct microscopy and culture. The sequencing of the nuclear ribosomal ITS region and β-tubulin gene of the isolate established its T. interdigitale lineage. The patient was cured by treatment with systemic terbinafine in combination with topical application of 1% naftifine-0.25% ketaconazole cream for 2 weeks.
Assuntos
Humanos , Feminino , Adolescente , Tinha/patologia , Trichophyton/isolamento & purificação , Sobrancelhas/microbiologia , Sobrancelhas/patologia , Dermatoses Faciais/microbiologia , Dermatoses Faciais/patologia , Tinha/tratamento farmacológico , Urease/análise , Microscopia Eletrônica de Varredura , Resultado do Tratamento , Dermoscopia , Dermatoses Faciais/tratamento farmacológico , Antifúngicos/uso terapêutico , Naftalenos/uso terapêuticoRESUMO
Genital molluscum contagiosum is rare in children. We report a molluscum contagiosum around the vulva and anus of 9-year-old girl, which has atypical presentations and was finally confirmed by histopathological and electron microscopy findings.
Assuntos
Doenças dos Genitais Femininos/patologia , Molusco Contagioso/patologia , Canal Anal/patologia , Biópsia , Criança , Dermoscopia , Feminino , Humanos , Microscopia Eletrônica de Transmissão , Vulva/patologiaRESUMO
Abstract Genital molluscum contagiosum is rare in children. We report a molluscum contagiosum around the vulva and anus of 9-year-old girl, which has atypical presentations and was finally confirmed by histopathological and electron microscopy findings.
Assuntos
Criança , Feminino , Humanos , Doenças dos Genitais Femininos/patologia , Molusco Contagioso/patologia , Canal Anal/patologia , Biópsia , Dermoscopia , Microscopia Eletrônica de Transmissão , Vulva/patologiaRESUMO
Infantile hemangiomas can present a therapeutic challenge to clinicians, especially when associated with severe pain and feeding difficulties. The standard therapeutic management includes corticosteroids and propranolol. However, the clinical response is not always satisfactory. We present six cases of infantile hemangiomas successfully treated with oral itraconazole approximately 5 mg/kg per day. In the first month, the red color of the lesions became a little lighter and the growth of the lesions was controlled in all cases. An obvious clinical improvement was noted in all cases during the 3-month period, with 80-100% improvement in each patient at the end of the treatment, which was judged by both their parents and the dermatologists. Compliance with treatment instructions of oral itraconazole in infants was judged to be very good. Side-effects were mild and limited. Although itraconazole can inhibit angiogenesis and tumor growth in vitro and in vivo associated with some cancers, further research is required to understand the pathogenesis of infantile hemangiomas and the mechanism of itraconazole.