RESUMO
INTRODUCTION: According to the criteria of Hodges and Warlow, transient global amnesia is defined by sudden onset of isolated anterograde amnesia of spontaneous resolution within one to twenty-four hours. Its pathophysiological mechanisms are still uncertain. METHODS: In a retrospective study, we have analyzed epidemiological, clinical and MRI data from twelve patients admitted to the only neurological department of French Polynesia for transient global amnesia corresponding to the criteria of Hodges and Warlow between January 2010 and December 2013. RESULTS: The median age of the cohort was 61.5 (53-72), the sex ratio was 1. Ten patients had one or more cardiovascular risk factors, 3 had migraine headaches and 3 had anxiodepressive disorders. Among triggers found, the occurrence during the rest was noted in one case. Retrograde amnesia was observed in 42% of cases, repetitive questioning in 75% of cases, anxious bewilderment in 67% of cases and disorientation in 33% of cases. The median episode duration was 9 hours and the duration of hospitalization was 3 days. Three patients had a recurrence. MRI was abnormal in all patients and showed diffusion-weighted hyperintensities in right (n=8), left (n=3) and bilateral (n=1) hippocampi. CONCLUSION: Epidemiological, clinical and MRI data from our cohort are similar to those from the literature except for the highest prevalence of cardiovascular risk factors and the most frequent right hippocampus involvement. Transient global amnesia occurring exceptionally while sleeping was also observed in one of our patients.
Assuntos
Amnésia Global Transitória/epidemiologia , Idoso , Amnésia Global Transitória/etnologia , Amnésia Global Transitória/patologia , Amnésia Global Transitória/psicologia , Transtornos de Ansiedade/epidemiologia , Comorbidade , Confusão/etiologia , Transtorno Depressivo/epidemiologia , Imagem de Difusão por Ressonância Magnética , Dislipidemias/epidemiologia , Feminino , Hipocampo/patologia , Humanos , Hipertensão/epidemiologia , Masculino , Pessoa de Meia-Idade , Transtornos de Enxaqueca/epidemiologia , Havaiano Nativo ou Outro Ilhéu do Pacífico/psicologia , Polinésia/epidemiologia , Recidiva , Estudos Retrospectivos , Fatores de Risco , Transtornos Intrínsecos do Sono/etiologia , Fumar/epidemiologiaRESUMO
We consider a sonic analog of a black hole realized in the one-dimensional flow of a Bose-Einstein condensate. Our theoretical analysis demonstrates that one- and two-body momentum distributions accessible by present-day experimental techniques provide clear direct evidence (i) of the occurrence of a sonic horizon, (ii) of the associated acoustic Hawking radiation, and (iii) of the quantum nature of the Hawking process. The signature of the quantum behavior persists even at temperatures larger than the chemical potential.