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1.
J Nanosci Nanotechnol ; 19(10): 6641-6646, 2019 10 01.
Artigo em Inglês | MEDLINE | ID: mdl-31027004

RESUMO

This study examined the effects of additives to improve the COS absorption capacity of Cu-Al-based sorbents for the integrated gasification fuel cell (IGFC) process. To absorb a small amount of COS, an Al-based precursor was added to the precursor solution for Cu-Al-based sorbents because a high surface area absorber was required. Various transition metals (Zn, Fe, Mn) were used as additives to improve the stability of the Cu-Al-based absorbent. The changes in surface properties and sulfur absorption capacity of the Cu-Al-based absorbent were investigated according to the composition of transition metals. As a result of the sulfur absorption test, the difference in the sulfur absorption capacity of the Cu-based sorbents was confirmed depending on the type of additive, and changes in their surface area. Moreover, the pore characteristics were observed by the nitrogen adsorption method. Sorbents with high surface areas generally have high sulfur capacity, but the additive component has a strong effect. These results can be explained by the transition metal additive binding to Cu to form a composite metal oxide. Furthermore, manganese was found to be suitable for improving the stability and surface area of the copper-based absorbent.

2.
J Craniofac Surg ; 29(5): 1220-1223, 2018 Jul.
Artigo em Inglês | MEDLINE | ID: mdl-29521744

RESUMO

BACKGROUND: Nasal septal cartilage and conchal cartilages are preferred sources of grafts in augmentation rhinoplasty. Rib cartilage can also be used, but it may evoke a patient's concerns about a scar and an extensive surgery. In such cases, irradiated homologous costal cartilage (IHCC) can be a useful alternative. However, controversy still exists in many literatures regarding complications with use of IHCC. Therefore, the authors reviewed our experiences with IHCC in rhinoplasty and analyzed the complications in relation to graft location. METHODS: A retrospective chart review was made of all patients who underwent rhinoplasty with IHCC between 2007 and 2015. A total of 323 patients were included. The authors considered the cases that required revision surgery for external aesthetic changes as complications. The authors defined major complications, including resorption, infection, fracture, or warping. RESULTS: The total complication rate was 8%. Two fractures (0.6%), 4 fragmentation (1.2%), 4 resorptions (1.2%), 4 infections (1.2%), and 2 warpings (0.6%) were noted. Most of these complications occurred for the septal extension graft. Other complications, including 1 nasal obstruction, 2 visible contours, 3 caudal septal deviations, and 4 cases of unfavorable results (patient unsatisfactions), were noted. CONCLUSIONS: Based on the outcomes of this study, the authors concluded that IHCC is a useful and reliable source of cartilage graft and can serve as an alternative graft material for rhinoplasty. However, care must be taken in use of IHCC graft in areas under tension such as septal extension graft, though its complication rate is low.


Assuntos
Aloenxertos/transplante , Cartilagem Costal/transplante , Rinoplastia , Humanos , Complicações Pós-Operatórias , Estudos Retrospectivos , Rinoplastia/efeitos adversos , Rinoplastia/instrumentação , Rinoplastia/métodos , Rinoplastia/estatística & dados numéricos
3.
J Endod ; 43(3): 364-369, 2017 Mar.
Artigo em Inglês | MEDLINE | ID: mdl-28110919

RESUMO

INTRODUCTION: We aimed to simultaneously investigate the effects of topical anesthesia on needle insertion and injection pain in the labial mucosa of the maxillary central incisors of patients awaiting apical surgery and to assess the relationship between patients' anxiety and pain scores. METHODS: Forty-four patients scheduled for apical surgery of the maxillary anterior incisor or canine were included, and all completed the Modified Dental Anxiety Scale (MDAS) questionnaire. One piece of Xylocaine (AstraZeneca, Sodertalje, Sweden) gauze was applied to the right or left side of the labial vestibule below the central incisor according to a randomization process, and 1 piece of water gauze was applied to the contralateral side of the labial vestibule. Each piece of gauze remained in place for 2 minutes. The subjects were asked to rate their pain according to the numeric rating scale immediately after needle insertion and anesthetic solution injection. RESULTS: Topical anesthetic application significantly reduced both insertion- and injection-related pain. Injection pain was significantly higher than insertion pain throughout the experiment. The difference in pain scores between the placebo and topical anesthetic groups was significantly greater for insertion pain than injection pain. The group with higher MDAS scores showed significantly higher pain scores, except for insertion pain reported by the topical anesthetic group, which did not show a significant difference between MDAS score groups. CONCLUSIONS: The topical anesthetic was highly effective for both insertion and injection pain during infiltration anesthesia in the maxillary central incisors. Highly anxious patients reported higher pain scores; however, topical anesthetics reduced the effect of anxiety on increasing pain.


Assuntos
Anestesia Local , Anestésicos Locais/administração & dosagem , Ansiedade/etiologia , Injeções/psicologia , Dor/psicologia , Adulto , Idoso , Anestesia Dentária , Método Duplo-Cego , Feminino , Humanos , Injeções/efeitos adversos , Masculino , Pessoa de Meia-Idade , Dor/etiologia , Dor/prevenção & controle , Medição da Dor , Inquéritos e Questionários , Adulto Jovem
4.
J Endod ; 41(8): 1371-4, 2015 Aug.
Artigo em Inglês | MEDLINE | ID: mdl-25777501

RESUMO

Tooth autotransplantation is a viable treatment option for tooth replacement when a suitable donor tooth is available. These case reports described significant vertical bone growth after autotransplantation of a mature third molar. The left mandible third molars (n = 2) were transplanted to the missing tooth in the left mandible. The patient follow-up period was 10 years after transplantation. Clinical examination revealed no mobility of the transplanted tooth. Radiographic examination indicated that bone regeneration occurred around the transplanted tooth. Vertical bone growth was observed in the cervical area of the root surface and the recipient bone. In autotransplantation of mature teeth, long-term follow-up results indicate that vertical bone growth can be expected if viability of the periodontal ligament cells is maintained.


Assuntos
Arcada Osseodentária/fisiopatologia , Dente Serotino/fisiopatologia , Dente Serotino/transplante , Procedimentos Cirúrgicos Ortognáticos , Osteogênese , Transplante Autólogo , Adulto , Cárie Dentária/cirurgia , Seguimentos , Humanos , Arcada Osseodentária/diagnóstico por imagem , Masculino , Pessoa de Meia-Idade , Dente Serotino/diagnóstico por imagem , Tomografia Computadorizada por Raios X , Erupção Ectópica de Dente/cirurgia , Transplante Autólogo/métodos
5.
J Endod ; 39(12): 1491-7, 2013 Dec.
Artigo em Inglês | MEDLINE | ID: mdl-24238435

RESUMO

INTRODUCTION: This prospective study examined the potential prognostic factors of endodontic microsurgery and compared the predictors of an isolated endodontic lesion with those of both an isolated endodontic lesion and an endodontic-periodontal lesion. METHODS: Data were collected from the Microscope Center of the Department of Conservative Dentistry at the Dental College of Yonsei University, Seoul, Korea, between March 2001 and March 2011. A total number of 584 teeth were included, and all clinical procedures were performed by a single operator (E.K.). The evaluation was performed at least 1 year after surgery. For statistical analysis of the predisposing factors, the chi-square test and logistic regression were performed. RESULTS: Of the 584 cases treated, 431 cases came for recall after a period of at least 12 months. Sex (female), tooth position (anterior), arch type (maxilla), and lesion type (isolated endodontic lesion) were found to have a positive effect on surgical outcome. With regards to isolated endodontic lesions, the tooth position (anterior), arch type (maxilla), and type of restoration (single/splinted crown, short bridge, and removable partial denture abutment) were found to be pure positive predictors. CONCLUSIONS: In endodontic microsurgery, it is likely that preoperative factors, particularly the tooth position and arch type, have a greater influence on the healing outcome than intra- and post-operative factors.


Assuntos
Apicectomia/métodos , Microcirurgia/métodos , Adulto , Compostos de Alumínio/uso terapêutico , Compostos de Cálcio/uso terapêutico , Coroas , Dente Suporte , Arco Dental/anatomia & histologia , Doenças da Polpa Dentária/cirurgia , Adesivos Dentinários/uso terapêutico , Combinação de Medicamentos , Feminino , Seguimentos , Humanos , Masculino , Mandíbula/anatomia & histologia , Maxila/anatomia & histologia , Metilmetacrilatos/uso terapêutico , Microcirurgia/instrumentação , Pessoa de Meia-Idade , Óxidos/uso terapêutico , Doenças Periapicais/cirurgia , Piezocirurgia/instrumentação , Piezocirurgia/métodos , Prognóstico , Estudos Prospectivos , Obturação Retrógrada/instrumentação , Obturação Retrógrada/métodos , Materiais Restauradores do Canal Radicular/uso terapêutico , Silicatos/uso terapêutico , Dente/cirurgia , Resultado do Tratamento , Adulto Jovem , Cimento de Óxido de Zinco e Eugenol/uso terapêutico
6.
J Endod ; 39(11): 1461-6, 2013 Nov.
Artigo em Inglês | MEDLINE | ID: mdl-24139275

RESUMO

INTRODUCTION: Autotransplantation of immature teeth can be an option for premature tooth loss in young patients as an alternative to immediately replacing teeth with fixed or implant-supported prostheses. The present case series reports 4 successful autotransplantation cases using computer-aided rapid prototyping (CARP) models with immature third molars. METHODS: The compromised upper and lower molars (n = 4) of patients aged 15-21 years old were transplanted with third molars using CARP models. Postoperatively, the pulp vitality and the development of the roots were examined clinically and radiographically. The patient follow-up period was 2-7.5 years after surgery. RESULTS: The long-term follow-up showed that all of the transplants were asymptomatic and functional. Radiographic examination indicated that the apices developed continuously and the root length and thickness increased. The final follow-up examination revealed that all of the transplants kept the vitality, and the apices were fully developed with normal periodontal ligaments and trabecular bony patterns. CONCLUSIONS: Based on long-term follow-up observations, our 4 cases of autotransplantation of immature teeth using CARP models resulted in favorable prognoses. The CARP model assisted in minimizing the extraoral time and the possible Hertwig epithelial root sheath injury of the transplanted tooth.


Assuntos
Autoenxertos/transplante , Desenho Assistido por Computador , Dente Serotino/transplante , Planejamento de Assistência ao Paciente , Adolescente , Tomografia Computadorizada de Feixe Cônico/métodos , Polpa Dentária/fisiologia , Feminino , Seguimentos , Humanos , Masculino , Modelos Anatômicos , Dente Molar/cirurgia , Odontogênese/fisiologia , Periodontite Periapical/terapia , Ligamento Periodontal/anatomia & histologia , Cirurgia Assistida por Computador , Ápice Dentário/crescimento & desenvolvimento , Extração Dentária/métodos , Raiz Dentária/crescimento & desenvolvimento , Adulto Jovem
7.
J Periodontal Implant Sci ; 42(5): 158-65, 2012 Oct.
Artigo em Inglês | MEDLINE | ID: mdl-23185696

RESUMO

PURPOSE: Recent interest has focused on intentional replantation to restore an original tooth. Some studies have shown successful results with intentional replantation for periodontally involved teeth. For long-term success of replantation, a healthy periodontal status of the recipient site is required so that delayed replantation is more suitable for periodontally involved teeth. To reveal the ideal timing for delayed replantation of periodontally involved teeth, the healing process of extraction sockets after extraction of periodontitis-induced teeth in rats was evaluated. METHODS: Twenty-eight rats were randomly divided into two groups: a control group (n=8) and test group (n=20). In the test group, periodontitis was induced by a ligature around the cervix of the mandibular first molar of all of the rats. Two weeks later, the mandibular first molars were extracted in all of the animals. The animals were sacrificed on days 0, 3, 7, and 10 after extraction and histological and immunohistochemical analysis was performed. RESULTS: In histological analysis of the test group, inflammatory cell infiltrate was found abundantly in the remaining periodontium 3 days after tooth extraction and decreased gradually at later time points. In immunohistochemical analysis of the test group, both interleukin-6 (IL-6) and, tumor necrosis factor-α (TNF-α) were numerous in the furcation area at each postextraction day. IL-6 was stained more heavily between 3 and 7 days after extraction; at day 10 after extraction, little staining was observed. TNF-α staining was more intense at 3 days after extraction and gradually weakened at later points in time. CONCLUSIONS: Within the limits of this study, it takes at least 10 days to resolve periodontal inflammation in rat extraction sockets.

8.
J Endod ; 37(7): 927-33, 2011 Jul.
Artigo em Inglês | MEDLINE | ID: mdl-21689546

RESUMO

INTRODUCTION: This retrospective study examined the potential prognostic factors on the outcome after endodontic microsurgery and compared the predictors of isolated endodontic lesion with those of both isolated endodontic lesions and endodontic-periodontal lesions. METHODS: The data were collected from patients with a history of endodontic microsurgery performed between August 2004 and December 2008 and at least 1 year before being evaluated. Surgical procedures were performed by the endodontic faculty and residents. After surgery, an operation record form was made with the preoperative, intraoperative, and postoperative factors from the clinical and radiographic measures. For statistical analysis of the predisposing factors, the dependent variable was the dichotomous outcome (ie, success vs failure). RESULTS: Of 907 cases, 491 were retained at follow-up. At the 0.05 level of significance, age, sex (female), tooth position (anterior), root-filling length (inadequate), [corrected] lesion type (endodontic lesion), root-end filling material (mineral trioxide aggregate and Super EBA; Harry J. Bosworth, Skokie, IL), and restoration at follow-up appeared to have a positive effect on the outcome. On the other hand, with an isolated endodontic lesion, the tooth position (anterior), root-filling length (inadequate), [corrected] and restoration at follow-up were significant factors at the 95% confidence level. CONCLUSIONS: Under the control of the significant variables in logistic regression, the potential prognostic factors on the outcome were sex, tooth position, lesion type, and root-end filling material. On the other hand, the tooth position was a pure predictor of an endodontic lesion affecting the clinical outcome.


Assuntos
Microcirurgia/métodos , Periodontite Periapical/prevenção & controle , Tecido Periapical/cirurgia , Tratamento do Canal Radicular/métodos , Raiz Dentária/cirurgia , Adolescente , Adulto , Idoso , Falha de Restauração Dentária , Feminino , Humanos , Estudos Longitudinais , Masculino , Pessoa de Meia-Idade , Periodontite Periapical/cirurgia , Prognóstico , Estudos Retrospectivos , Fatores de Risco , Resultado do Tratamento , Adulto Jovem
9.
Artigo em Inglês | MEDLINE | ID: mdl-20219604

RESUMO

OBJECTIVES: This study evaluated the efficacy of EndoVac system in comparison with that of a conventional needle irrigation method when the root canals were enlarged to various sizes. STUDY DESIGN: Sixty-nine single-rooted teeth were divided into 3 groups according to the root canal irrigation system (24G and 30G needle and EndoVac). Each group was divided into 3 subgroups according to the MAF size (#25, #40, and #60). Four-micron-thick serial sections were prepared at 1.5 and 3.5 mm from the apical level and photographs were taken for the analysis. The influence of the irrigation system and apical size was evaluated using a 1-way ANOVA test and Tukey's test (P < .05). RESULTS: At both levels, significant differences were detected between EndoVac system and conventional needle irrigation in removing debris (P < .05). The relationship between the MAF size and irrigation efficacy was found to have a positive relationship (P < .05). CONCLUSIONS: EndoVac left significantly less debris behind than the conventional needle irrigation methods. Although all 3 irrigation methods resulted in clean root canals because the percentage occupied by remaining debris was very low in our specimens, larger apical instrumentation seemed to improve apical root canal debridement.


Assuntos
Cavidade Pulpar/cirurgia , Irrigantes do Canal Radicular/administração & dosagem , Preparo de Canal Radicular/instrumentação , Irrigação Terapêutica/instrumentação , Análise de Variância , Desbridamento/instrumentação , Desbridamento/métodos , Instrumentos Odontológicos , Humanos , Incisivo , Preparo de Canal Radicular/métodos , Camada de Esfregaço , Estatísticas não Paramétricas , Irrigação Terapêutica/métodos , Ápice Dentário/cirurgia , Vácuo
10.
Artigo em Inglês | MEDLINE | ID: mdl-20123390

RESUMO

BioAggregate is a new product that was formulated for root-end filling, perforation repair, and pulp capping. This study examined the chemical differences between white mineral trioxide aggregate (MTA) and BioAggregate in both powder and set forms using X-ray diffraction. The results showed that white MTA and BioAggregate have a similar chemical composition with some differences: BioAggregate contains a significant amount of tantalum oxide instead of bismuth oxide. In both groups, similar peaks were observed in the set and powder form, but sharper and stronger peaks were observed in the powder samples.


Assuntos
Materiais Restauradores do Canal Radicular/química , Cristalografia por Raios X , Teste de Materiais
11.
J Endod ; 34(5): 546-51, 2008 May.
Artigo em Inglês | MEDLINE | ID: mdl-18436032

RESUMO

The aim of this study was to evaluate the outcomes of endodontic microsurgery by comparing the healing success of cases having a lesion of endodontic origin compared with cases having a lesion of combined endodontic-periodontal origin. Data were collected from patients in the Department of Conservative Dentistry, Dental College, Yonsei University, Seoul, Korea between March 2001 and June 2005. A total number of 263 teeth from 227 patients requiring periradicular surgery were included in this study. Patients were recalled every 6 months for 2 years and every year thereafter to assess clinical and radiographic signs of healing. A recall rate of 73% (192 of 263 patients) was obtained. The successful outcome for isolated endodontic lesions was 95.2%. In endodontic-periodontal combined lesions, successful outcome was 77.5%, suggesting that lesion type (ABC vs DEF) had a strong effect on tissue and bone healing.


Assuntos
Apicectomia/métodos , Doenças da Polpa Dentária/cirurgia , Microcirurgia/métodos , Periodontite Periapical/cirurgia , Obturação Retrógrada/métodos , Adolescente , Adulto , Idoso , Perda do Osso Alveolar/cirurgia , Criança , Fístula Dentária/cirurgia , Feminino , Humanos , Masculino , Pessoa de Meia-Idade , Estudos Prospectivos , Resultado do Tratamento , Ultrassom
12.
Artigo em Inglês | MEDLINE | ID: mdl-16632282

RESUMO

Nonsurgical endodontic therapy of a right mandibular first molar with 3 distal roots was successfully performed with the aid of magnification. 3D data (DICOM format) of the tooth were obtained from a CT HighSpeed Advantage and a Denta Scan program produced by GE Medical Systems. The CT protocol used for this procedure involved a slit thickness of 1 mm. The 3D digital data obtained were fed into a visualization program (V-works; Cybermed Co) and then exported to the rapid prototyping machine for fabrication of the actual-sized tooth model. The material for the model-making process was starch. The 3D digital visualization and the computer-aided rapid prototyping (CARP) model clearly showed 3 separate distal roots (distobuccal, distolingual, and middle distal). The CARP technique seems to be a useful imaging technology to document unusual root anatomy in clinical dentistry.


Assuntos
Fístula Dentária/diagnóstico por imagem , Processamento de Imagem Assistida por Computador/métodos , Imageamento Tridimensional/métodos , Modelos Dentários , Dente Molar/anatomia & histologia , Abscesso Periapical/diagnóstico por imagem , Raiz Dentária/anatomia & histologia , Adulto , Desenho Assistido por Computador , Fístula Dentária/etiologia , Fístula Dentária/terapia , Cavidade Pulpar/anatomia & histologia , Feminino , Humanos , Mandíbula , Microscopia , Dente Molar/diagnóstico por imagem , Abscesso Periapical/complicações , Abscesso Periapical/terapia , Tomografia Computadorizada por Raios X , Raiz Dentária/diagnóstico por imagem
13.
Artigo em Inglês | MEDLINE | ID: mdl-15953925

RESUMO

OBJECTIVES: Autotransplantation is a viable option for treating missing teeth when a donor tooth is available. The aim of this study was to evaluate the prognosis in addition to the causes of failure in 182 autotransplanted teeth. STUDY DESIGN: A total of 182 cases of autotransplantation were analyzed. All the transplants were performed according to a computer-aided rapid prototyping technique with an average extraoral time of 7.58 minutes. These cases were followed for 2 to 60 months after surgery. The prognosis was divided into 4 groups, complete healing, incomplete healing, uncertain healing, and failure. The initial stability, root resorption, and ankylosis were also analyzed. RESULTS: Most transplanted teeth showed complete healing between postoperative 2 months and 8 months. The transplanted teeth with a good initial stability showed better initial healing than those with a poor initial stability. The average extraoral time was 7.58 min (range: immediately after extraction up to 25 min). There was no relationship (P > .05) between the extraoral time and either root resorption (4 cases, 2.4%) or ankylosis (18 cases, 10.7%) within this experimental time period. Nine cases (4.5%) failed. CONCLUSION: This study showed a 4.5% failure rate during the short to intermediate observation period. Autotransplantation is a very useful method for replacing missing teeth, provided that the extraoral time and other factors are well controlled.


Assuntos
Procedimentos Cirúrgicos Bucais/métodos , Dente/transplante , Transplante Autólogo/efeitos adversos , Adolescente , Adulto , Idoso , Feminino , Seguimentos , Humanos , Masculino , Pessoa de Meia-Idade , Modelos Dentários , Procedimentos Cirúrgicos Bucais/efeitos adversos , Prognóstico , Reabsorção da Raiz/etiologia , Cirurgia Assistida por Computador , Preservação de Tecido , Anquilose Dental/etiologia , Extração Dentária , Mobilidade Dentária/etiologia , Falha de Tratamento , Cicatrização
14.
Artigo em Inglês | MEDLINE | ID: mdl-14561971

RESUMO

OBJECTIVES: The purpose of this study was to compare the gutta-percha-filled area in oval canals while varying the temperature and penetration depth of the System B plugger. STUDY DESIGN: Seventy-five resin blocks, with artificially created oval canals, were obturated by using a continuous wave technique. In groups 1, 2, and 3, the plugger was introduced to a depth of 4 mm from the apex at set temperatures of 100, 200, and 350 degrees C, respectively. In group 4, the plugger was inserted to a depth of 2 mm from the apex at a set temperature of 200 degrees C. Group 5 was obturated in the same way as group 2, and then an additional cold plugging was performed to a depth of 3 mm from the apex. The cross sections of the obturated canals were photographed, and the percentage of the gutta-percha-filled area (PGP) was measured. RESULTS: No significant differences were found between the 3 different temperature settings (P >.05). At 1 mm from the apex, group 4 showed the highest PGP (95.57% +/- 6.86), followed by group 5 (84.72% +/- 12.19), and group 2 (67.33 +/- 13.03) (P <.05). CONCLUSION: In artificially created oval canals, plugger temperature within the range used in this study did not affect the PGP. However, the penetration depth of the plugger was significantly related to PGP.


Assuntos
Cavidade Pulpar/anatomia & histologia , Obturação do Canal Radicular/métodos , Resinas Acrílicas , Análise de Variância , Guta-Percha , Humanos , Modelos Dentários , Obturação do Canal Radicular/instrumentação , Temperatura , Ápice Dentário/anatomia & histologia
15.
J Endod ; 29(1): 28-30, 2003 Jan.
Artigo em Inglês | MEDLINE | ID: mdl-12540215

RESUMO

The objective of this study was to investigate the ability of alendronate and taurine in inhibiting in vitro osteoclast differentiation induced by bacteria. Whole cell sonicates of Porphyromonas gingivalis were used as an osteoclast-stimulating factor in a mouse coculture system and differentiated osteoclasts were confirmed by tartrate-resistant acid phosphatase (TRAP) staining. Alendronate at the concentrations of 10(-7) M, 10(-6) M, and 10(-5) M and taurine at the concentrations of 4 mM, 8 mM, and 12 mM were used. The cytotoxic effects of alendronate and taurine were examined using methylthiazole-tetrazolium bromide (MTT) assay. The amounts of interleukin-6 (IL-6) in culture supernatants were also measured using ELISA. The sonicates of P. gingivalis at the concentration of 0.01-0.1 microg/ml significantly stimulated the formation of osteoclasts (p < 0.05). Alendronate (10(-5) M) and taurine (12 mM) significantly suppressed the sonicate-stimulated osteoclast formation. In MTT assay, no cytotoxic effects were evident in all concentrations of alendronate and taurine. Alendronate and taurine did not affect the amount of IL-6 induced by P. gingivalis sonicates. These data indicate that alendronate and taurine have inhibitory effects on bacteria-stimulated osteoclast formation in vitro and that this inhibitory mechanism is not related to the blocking of IL-6 production.


Assuntos
Alendronato/administração & dosagem , Diferenciação Celular/efeitos dos fármacos , Osteoclastos/efeitos dos fármacos , Irrigantes do Canal Radicular/análise , Taurina/administração & dosagem , Animais , Células da Medula Óssea , Células Cultivadas , Técnicas de Cocultura , Interleucina-6/biossíntese , Camundongos , Camundongos Endogâmicos ICR , Osteoclastos/citologia , Osteoclastos/microbiologia , Porphyromonas gingivalis/fisiologia , Reabsorção da Raiz/prevenção & controle , Crânio/citologia , Sonicação
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