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1.
Braz. j. otorhinolaryngol. (Impr.) ; 89(3): 425-431, May-June 2023. tab
Artigo em Inglês | LILACS-Express | LILACS | ID: biblio-1447711

RESUMO

Abstract Objectives This study aimed to assess the prevalence of oral lesions in patients living with HIV infection and their association with CD4 count, viral load, and antiretroviral therapy in patients with HIV. Methods A cross-sectional study was conducted on a sample of 161 patients attending the… All the patients were examined for their oral lesions, current CD4 counts, type, and duration of the therapy. Data analyses were carried out using Chi-Square, Student T/Mann-Whitney, and logistic regression tests. Results Oral lesions were observed in 58.39% of patients with HIV. Periodontal disease with 78 (48.45%) or without mobility 79 (49.07%) was observed more frequently, followed by hyperpigmentation of oral mucosa 23 (14.29%), Linear Gingival Erythema (LGE) 15 (9.32%), candidiasis pseudomembranous 14 (8.70%). Oral Hairy Leukoplakia (OHL) was observed only in 3 (1.86%). A relationship between periodontal disease with dental mobility and smoking was found (p = 0.04), as well duration of treatment (p = 1.53e-3) and age (p = 0.02). Hyperpigmentation was related to race (p = 0.01) and smoking (p = 1.30e-6). CD4 count, CD4:CD8 ratio, viral load, or type of treatment were not associated with oral lesions. Logistic regression showed that the duration of treatment has a protective effect on the periodontal disease with dental mobility (OR = 0.28 [−2.27 to −0.25]; p-value = 0.03), independent of age or smoking. To hyperpigmentation, the best model included smoking (OR = 8.47 [1.18-3.10], p = 1.31e-5), without race or type and duration of treatment. Conclusion Among HIV patients undergoing antiretroviral treatment, oral lesions can be observed, predominantly periodontal disease. Pseudomembranous candidiasis and oral hairy leukoplakia were also observed. No relationship was found between associated oral manifestations in HIV patients and the start of the treatment, TCD4+ and TCD8+ cell count, TCD4:TCD8 ratio, or viral load. The data indicate that there is a protective effect of duration of treatment with relation to periodontal disease with mobility and that hyperpigmentation seems to be more related to smoking than type and duration of treatment. Level of evidence Level 3 (OCEBM Levels of Evidence Working Group*. "The Oxford 2011 Levels of Evidence").

2.
Braz J Otorhinolaryngol ; 89(3): 425-431, 2023.
Artigo em Inglês | MEDLINE | ID: mdl-36813599

RESUMO

OBJECTIVES: This study aimed to assess the prevalence of oral lesions in patients living with HIV infection and their association with CD4 count, viral load, and antiretroviral therapy in patients with HIV. METHODS: A cross-sectional study was conducted on a sample of 161 patients attending the… All the patients were examined for their oral lesions, current CD4 counts, type, and duration of the therapy. Data analyses were carried out using Chi-Square, Student T/Mann-Whitney, and logistic regression tests. RESULTS: Oral lesions were observed in 58.39% of patients with HIV. Periodontal disease with 78 (48.45%) or without mobility 79 (49.07%) was observed more frequently, followed by hyperpigmentation of oral mucosa 23 (14.29%), Linear Gingival Erythema (LGE) 15 (9.32%), candidiasis pseudomembranous 14 (8.70%). Oral Hairy Leukoplakia (OHL) was observed only in 3 (1.86%). A relationship between periodontal disease with dental mobility and smoking was found (p=0.04), as well duration of treatment (p=1.53e-3) and age (p=0.02). Hyperpigmentation was related to race (p=0.01) and smoking (p=1.30e-6). CD4 count, CD4:CD8 ratio, viral load, or type of treatment were not associated with oral lesions. Logistic regression showed that the duration of treatment has a protective effect on the periodontal disease with dental mobility (OR = 0.28 [-2.27 to -0.25]; p-value=0.03), independent of age or smoking. To hyperpigmentation, the best model included smoking (OR=8.47 [1.18-3.10], p= 1.31e-5), without race or type and duration of treatment. CONCLUSION: Among HIV patients undergoing antiretroviral treatment, oral lesions can be observed, predominantly periodontal disease. Pseudomembranous candidiasis and oral hairy leukoplakia were also observed. No relationship was found between associated oral manifestations in HIV patients and the start of the treatment, TCD4+ and TCD8+ cell count, TCD4:TCD8 ratio, or viral load. The data indicate that there is a protective effect of duration of treatment with relation to periodontal disease with mobility and that hyperpigmentation seems to be more related to smoking than type and duration of treatment. LEVEL OF EVIDENCE: Level 3 (OCEBM Levels of Evidence Working Group*. "The Oxford 2011 Levels of Evidence").


Assuntos
Candidíase Bucal , Infecções por HIV , Hiperpigmentação , Doenças da Boca , Doenças Periodontais , Humanos , Infecções por HIV/complicações , Infecções por HIV/tratamento farmacológico , Leucoplasia Pilosa/epidemiologia , Leucoplasia Pilosa/complicações , Doenças da Boca/etiologia , Estudos Transversais , Brasil/epidemiologia , Candidíase Bucal/epidemiologia , Candidíase Bucal/complicações , Doenças Periodontais/complicações , Hiperpigmentação/complicações
3.
Spec Care Dentist ; 43(2): 144-151, 2023 Mar.
Artigo em Inglês | MEDLINE | ID: mdl-35849847

RESUMO

AIM: To verify the association of the TNF-α, IL-6, and IL-10 polymorphisms with chronic temporomandibular disorder pain development in female elderly patients. METHODS: Participants were evaluated according to Diagnostic Criteria for Temporomandibular Disorders. The genomic DNA was extracted from blood according to the Salting Out method followed by a quantification using the NanoDrop spectrophotometer. The -308G/A TNF-α polymorphism analysis was performed by the polymerase chain reaction-restriction fragment length polymorphism technique, the determination of -174G/C IL-6 polymorphism was performed by polymerase chain reaction, and the evaluation of the -1082A/G IL-10 polymorphism was carried out by polymerase chain reaction- allele-specific amplification. Data were analyzed using the BioEstat 5.3 software. RESULTS: The -308G/A TNF-α polymorphism showed a significant difference when genotypes of cases with chronic temporomandibular disorder pain and controls were compared (p = .025). There was a lack of association regarding the -174G/C IL-6 polymorphism (p = .286) however, a positive association between the -1082A/G IL-10 polymorphism with chronic temporomandibular disorder was observed (p = .020). CONCLUSION: The analyzed data of elderly subjects support the possible involvement of the GA genotype of the -308G/A TNF-α and the AA genotype of the -1082A/G IL-10 polymorphisms in the pathogenesis of chronic temporomandibular disorder pain.


Assuntos
Interleucina-10 , Fator de Necrose Tumoral alfa , Humanos , Feminino , Idoso , Fator de Necrose Tumoral alfa/genética , Interleucina-10/genética , Interleucina-6/genética , Predisposição Genética para Doença , Polimorfismo Genético , Dor , Estudos de Casos e Controles
4.
Braz. dent. sci ; 26(1): 1-9, 2023. tab, ilus
Artigo em Inglês | BBO - Odontologia, LILACS | ID: biblio-1411432

RESUMO

Objective: to analyze the stress distribution in a 3D model that simulates second molar mesialization using two different types of mini-implants. Material and Methods: a mandible bone model was obtained by recomposing a computed tomography performed by a software program. The cortical and trabecular bone, a lower second molar, periodontal ligament, orthodontic tube, resin cement and the mini-implants were designed and modeled using the Rhinoceros 4.0 software program. The characteristics of self-drilling orthodontic mini-implants were: one with 7 mm length, 1 mm transmucosal neck section and 1.6 mm diameter and another with 5 mm length and 1.5 mm diameter. A total of 235.161 and 224.505 elements were used for the mesh. These models were inserted into the bone block and then subjected to loads of 200 cN (centinewton). The results were calculated and analyzed by the Ansys 17.0 software program for qualitative verification through displacement and maximum principal stress maps. Results: it was possible to observe that the periodontal ligament presented low displacement and stress values. However, the physiological values presented are among those capable to provide orthodontic movement, with compression and tensile area visualization staggered between 0.1 and -0.1 MPa (megapascal). Conclusion: within the limitations of the study, the mini-implants tested showed similar results where the load on the tooth allowed dental displacement (molar mesialization), with a tendency to rotate it, theoretically allowing the second molar to take the location of the first molar. (AU)


Objetivo: analisar a distribuição de tensões em um modelo 3D que simula a mesialização do segundo molar usando dois tipos diferentes de mini-implantes. Material e Métodos: um modelo de osso mandibular foi obtido por recomposição de uma tomografia computadorizada realizada por um software. O osso cortical e trabecular, um segundo molar inferior, ligamento periodontal, tubo ortodôntico, cimento resinoso e os mini-implantes foram projetados e modelados no software Rhinoceros 4.0. As características dos mini-implantes ortodônticos auto perfurantes foram: um com 7 mm de comprimento, 1 mm de secção transmucosa e 1,6 mm de diâmetro e outro com 5 mm de comprimento e 1,5 mm de diâmetro. Para a malha, foram utilizados 235.161 e 224.505 elementos. Esses modelos foram inseridos no bloco ósseo e então submetidos a cargas de 200 cN (centinewton). Os resultados foram calculados e analisados pelo software Ansys 17.0 para verificação qualitativa por meio de mapas de deslocamento e tensões máximas principais. Resultados: foi possível observar que o ligamento periodontal apresentou baixos valores de deslocamento e tensões. Porém, os valores fisiológicos apresentados são capazes de proporcionar movimentação ortodôntica, com visualização da área de compressão e tração escalonada entre 0,1 e -0,1 MPa (megapascal). Conclusão: dentro das limitações do estudo, os mini-implantes testados apresentaram resultados semelhantes onde a carga sobre o dente permitiu o deslocamento dentário (mesialização do molar), com tendência a girá-lo, permitindo teoricamente que o segundo molar ocupe do lugar do primeiro molar (AU)


Assuntos
Avulsão Dentária , Implantes Dentários , Análise de Elementos Finitos , Procedimentos de Ancoragem Ortodôntica , Aparelhos Ortodônticos Fixos
5.
Rev. odontol. UNESP (Online) ; 52: e20230027, 2023. tab, ilus
Artigo em Inglês | LILACS, BBO - Odontologia | ID: biblio-1530299

RESUMO

Introdução: O conhecimento da biomecânica de implantes de diâmetro reduzido indica dimensões seguras para uso clínico. Objetivo: O objetivo do presente estudo foi comparar biomecanicamente implantes de diâmetro regular e reduzido para suporte de próteses implantossuportadas unitárias na região anterior da maxila por meio de análise de elementos finitos 3D (3D-FEA). Material e método: Quatro modelos 3D-FEA foram desenvolvidos a partir de recomposição de tomografia computadorizada e dados da literatura: um bloco ósseo na região incisiva lateral superior direita com implante e coroa. M1: 3,75 x 13 mm, M2: 3,75 x 8,5 mm, M3: 2,9 x 13 mm e M4: 2,9 x 8,5 mm. Foi aplicada carga de 178 N nos ângulos 0, 30 e 60 graus em relação ao longo eixo do implante. Foram avaliados mapas de tensão de Von Mises, tensão principal máxima e microdeformação. Resultado: M3 e M4 apresentaram maiores valores de tensão e microdeformação que M1 e M2, principalmente quando foram aplicadas forças inclinadas. Porém, M3 apresentou comportamento biomecânico melhor do que M4. Conclusão: Pode-se concluir que reduzir o diâmetro dos implantes pode prejudicar a biomecânica durante a aplicação de forças, mas a distribuição e intensidade das tensões, bem como os valores de microdeformação podem ser melhorados se o comprimento do implante for aumentado


Introduction: Narrow diameter implants biomechanics knowledge indicates safe dimensions for clinical use. Objective: Purpose of the present study was biomechanically to compare regular and narrow diameter implants to support single implant-supported prosthesis in the anterior region of the maxilla by 3D finite element analysis (3D-FEA). Material and method: Four 3D-FEA models were developed form CT scan recompositing and literature data: a bone block in the right upper lateral incisive region with implant and crown. M1: 3.75 x 13 mm, M2: 3.75 x 8.5 mm, M3: 2.9 x 13 mm and M4: 2.9 x 8.5 mm. It was applied load was of 178 N at 0, 30 and 60 degrees in relation to implant long axis. Von Mises stress, maximum principal stress and microdeformation maps were evaluated. Result: M3 and M4 did show higher tension and higher microdeformation values than M1 and M2, especially when inclined forces were applied. However, M3 presented enhanced biomechanical behavior than M4. Conclusion: It can be concluded that reduce the diameter of the implants can disadvantage to the biomechanics during the application of forces, but the distribution and intensity of the stresses, as well as the micro deformation values can be improved if the length of the implant is increased


Assuntos
Próteses e Implantes , Estresse Mecânico , Fenômenos Biomecânicos , Osso e Ossos , Implantes Dentários , Análise de Elementos Finitos , Tomografia Computadorizada por Raios X , Maxila
6.
Oral Dis ; 28(7): 1770-1782, 2022 Oct.
Artigo em Inglês | MEDLINE | ID: mdl-34152659

RESUMO

The systematic review tried to answer the following question: Does the melatonin administered systemically or topically ameliorate patients involved with oral health conditions or dental procedures? The systematic review has been registered in the PROSPERO (2021CRD42021095959). Eligibility criteria included only randomized controlled clinical trials (RCTs) with at least 10 participants that compared patients that received melatonin as a treatment before and/or after their oral intervention topically or systemically, with control patients. A search was performed in PubMed/MEDLINE, Web of Science, Cochrane Library, and Academic Google databases for articles up to February 2021. The Cochrane risk-of-bias tool for randomized clinical trials was used and revealed that the studies included presented low risk of bias for the majority of criteria assessed. It was selected 25 articles, of which only six did not demonstrate positive effects and three presented null effects with the use of melatonin. Melatonin has improved the inflammatory response in periodontal disease, dental surgeries, and mucositis of head and neck oncologic irradiated patients. In addition, it showed anxiolytic potential in patients that were submitted to dental procedures. In conclusion, melatonin favored the treatment of oral changes when used topically and systemically.


Assuntos
Melatonina , Doenças Periodontais , Humanos , Melatonina/uso terapêutico , Saúde Bucal , Doenças Periodontais/tratamento farmacológico
7.
J. appl. oral sci ; 30: e20220298, 2022. graf
Artigo em Inglês | LILACS-Express | LILACS | ID: biblio-1421894

RESUMO

Abstract Temporomandibular disorders (TMD) is a term used to describe a set of clinical conditions that may compromise the temporomandibular joint (TMJ) and masticatory muscles and/or associated structures, considered the most frequent cause of orofacial pain of non-dental origin. In recent years, many forms of physical therapy have been used in the treatment of TMD to reduce pain and improve the range of mandibular movement present in this impairment. Among these resources are kinesiotherapy (exercise), electrothermal and manual therapy, acupuncture, training posture, mobilizations, and biofeedback. Objectives To determine if exercises with or without occlusal splints are effective in reducing pain in patients with temporomandibular disorders (TMD) of myogenic origin. Methodology This systematic review was registered in the International Prospective Register of Systematic Reviews (CRD 42019134244). Controlled trials published in PubMed, Scopus, and Cochrane Library following PRISMA guidelines up to April 2022 were randomized and included. The population above 18 years, which evaluated the effectiveness of exercise with or without occlusal splints in reducing pain in patients with TMD of myogenic origin, diagnosed through the Research Diagnostic Criteria for Temporomandibular Disorders, was also included. There was no restriction on the period of publication. Cochrane risk of bias analysis was performed. Results Of the five included articles, all showed a reduction of pain, but without significant differences between the interventions performed. Additionally, studies that evaluated the quality of life and mandibular movements showed a reduction in pain, but no significant differences between therapies. Conclusion The analyzed studies showed no difference in the improvement of pain, quality of life, and mandibular movements between the groups that performed only exercises or the associated treatments.

8.
J. appl. oral sci ; 29: e20210262, 2021. graf
Artigo em Inglês | LILACS | ID: biblio-1356418

RESUMO

Abstract This study aimed to investigate if SNP rs6313, SNP rs2770304, SNP rs4941573, and SNP rs1923884 of the 5-HT2A receptor gene and SNP rs6295 of the 5-HT1A receptor gene are associated with bruxism etiology. Methodology This systematic review was registered in PROSPERO (CRD42018094561). A search was conducted for articles published in or before May 2021. To qualify for eligibility in this review, the studies had to be case-controls, cohort or cross-sectional. The inclusion criteria were the articles with a group of patients with bruxism and a control group in which the presence of these SNPs was evaluated. The exclusion criteria were the investigations of other polymorphisms, the studies that did not consider a control group for comparison, case reports, and reviews. The NOS and JBI were used to evaluate the methodological quality of studies. Results We conducted this study with databases, such as Web of Science, Scopus, Embase, PubMed/MEDLINE, and ProQuest. We considered four studies eligible. A total of 672 participants were included,187 with sleep bruxism, 105 with awake bruxism, 89 with sleep and awake bruxism, and 291 controls. One study found a strong association between the SNPs rs6313, rs2770304 and rs4941573 of the 5-HT2A receptor gene and sleep bruxism. In one study, we considered the C allele of the SNP rs2770304 a risk factor for sleep bruxism. We found no significant results of other SNPs in sleep bruxers compared to controls. We found no positive association concerning the SNPs and groups of awake bruxism and sleep and awake bruxism. Conclusion The different results regarding the SNPs in sleep bruxers could be explained by the genetic distinction between Chilean, Mexican, Japanese, and Polish population. More clinical trials and prospective studies must be conducted with larger sample size and in different ethnicities to confirm the results of this review.


Assuntos
Humanos , Bruxismo do Sono/genética , Receptor 5-HT1A de Serotonina/genética , Polimorfismo de Nucleotídeo Único
9.
J Oral Pathol Med ; 49(10): 961-968, 2020 Nov.
Artigo em Inglês | MEDLINE | ID: mdl-32274841

RESUMO

This study evaluated IL-6 salivary levels as well as the +3954 polymorphism of IL-1ß in patients with burning mouth syndrome and healthy individuals, through case-control studies. This systematic review and meta-analysis followed the Preferred Reporting Items for Systematic Reviews and Meta-Analyses guidelines. We conducted this research in PubMed/MEDLINE, Cochrane Library and Web of Science databases. The risk of bias was measured based in the Newcastle-Ottawa Scale. Researches with a group of patients with burning mouth syndrome and a control group in which the presence of the +3954 polymorphism of IL-1ß and/ or IL-6 salivary levels through non-stimulated saliva were evaluated to detect if this interleukin concentrations are increased in patients and if the polymorphism is a risk factor for this syndrome. We identified seven studies with total of 440 participants, 229 patients with burning mouth syndrome and 211 healthy controls, ages 24-84 years old. The female gender was predominant. Patients in the majority of studies did not present increased levels of IL-6 and the +3954 polymorphism of IL-1ß is not a risk factor for this syndrome. A few studies researched biomarkers in this pathology and more investigations are required not only to identify salivary levels and the polymorphism evaluated, but also other interleukins and polymorphisms in order to clarify the etiopathogenesis of this syndrome as well as for propose new diagnostic methods and treatments.


Assuntos
Síndrome da Ardência Bucal , Interleucina-6 , Adulto , Idoso , Idoso de 80 Anos ou mais , Síndrome da Ardência Bucal/genética , Feminino , Humanos , Interleucina-6/genética , Interleucinas , Pessoa de Meia-Idade , Polimorfismo Genético/genética , Saliva , Adulto Jovem
10.
Oral Maxillofac Surg ; 24(2): 133-144, 2020 Jun.
Artigo em Inglês | MEDLINE | ID: mdl-32056052

RESUMO

PURPOSE: The aim of this study was to perform a systematic review and meta-analysis to evaluate the efficacy of laser therapy on medication-related osteonecrosis of the jaw (MRONJ) treatment. METHODS: This study followed PRISMA standards, and an electronic search was performed on the PubMed/MEDLINE, Scopus, and Cochrane databases. Eighty-nine articles were found. After reading the manuscripts, 15 articles remained for the review. Three of them were selected for meta-analysis. RESULTS: Female gender was predominant (72.5%), and mean age was 66.5 years. Follow-up varied between 3 and 80 months, and the most used bisphosphonate was zoledronic acid (71.6%). Stage II of MRONJ was the most prevalent (68.9%), and the mandible was the most affected site (64.5%). Qualitative data showed that treatment with laser surgery (Er:YAG) was most effective regarding complete healing of the lesion (90%) compared with other treatments. Meta-analysis data showed that low-level laser therapy (LLLT) was more effective than medical treatment (P = 0.006), and surgical treatment was more effective than LLLT (P = 0.008). CONCLUSION: Laser surgery was significantly superior to LLLT (p < 0.00001). Therefore, laser surgical therapy seems to be a great management strategy for MRONJ treatment from stage II. LLLT was shown to improve conservative management in earlier MRONJ stages.


Assuntos
Osteonecrose da Arcada Osseodentária Associada a Difosfonatos , Conservadores da Densidade Óssea , Terapia a Laser , Osteonecrose , Idoso , Difosfonatos , Feminino , Humanos , Arcada Osseodentária
11.
J Prosthet Dent ; 124(4): 439-445, 2020 Oct.
Artigo em Inglês | MEDLINE | ID: mdl-31862146

RESUMO

STATEMENT OF PROBLEM: One-step dental implant surgery with a 1-piece implant has been introduced with the aim of simplifying and increasing the effectiveness of treatment and providing greater comfort for the patient. Whether these goals have been met compared with conventional 2-piece implants remains unclear. PURPOSE: The purpose of this systematic review and meta-analysis was to compare the use of 1-piece versus 2-piece implants in terms of marginal bone loss and implant survival rate. MATERIAL AND METHODS: This systematic review and meta-analysis adhered to the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines and was recorded in the International prospective register of systematic reviews (PROSPERO) database (CRD 42018095721). A literature search was conducted in the PubMed/MEDLINE, Web of Science, and Cochrane Library databases for articles published up to May 2018. The population, intervention, comparison, outcome (PICO) question was, "Do patients who received 1-piece implants show similar marginal bone loss, survival rates, and complications as those who receive 2-piece implants?" RESULTS: The meta-analysis was based on the Mantel-Haenszel and inverse variance methods. Implant survival rate was analyzed by using a dichotomous outcome, measured according to risk ratio (RR) and marginal bone loss by continuously evaluating the outcomes according to the mean difference (MD), both with a corresponding 95% confidence interval (CI). Five studies, including 270 participants with a mean age of 54.70 years and receiving 434 dental implants, were included. The mean follow-up period was 4 years. Meta-analysis did not reveal a significant difference in relation to implant survival rate (P=.85; RR: -0.89; CI: -0.27 to 2.98), as well as to marginal bone loss (P=.85; MD: -0.43; CI: -0.43 to -0.52). CONCLUSIONS: One- and 2-piece implants demonstrated effectiveness in the rehabilitation of patients requiring dental implants.


Assuntos
Doenças Ósseas Metabólicas , Implantes Dentários , Implantação Dentária Endóssea , Prótese Dentária Fixada por Implante , Falha de Restauração Dentária , Humanos , Pessoa de Meia-Idade
12.
Braz. j. oral sci ; 19: e201715, jan.-dez. 2020. ilus
Artigo em Inglês | BBO - Odontologia, LILACS | ID: biblio-1116536

RESUMO

Aim: Little is known about the reparability of glass ionomer cements (GICs) after storage in acid environments. The aim of this study was to evaluate the solubility and repairability of GICs immersed in acid solutions and subjected to brushing. Methods: Thirty discs of each GIC (Vitremer, VitroFil LC, VitroFil, and Maxxion R) were divided into three immersion groups: distilled water, Coca-Cola, or hydrochloric acid (HCl), then subjected to brushing. The weight of discs was measured before and after the immersions to determine mass alteration. Each disc was repaired, by adding the same brand of GIC over its surface. After immersing the repaired specimens in same solutions, shear bond strengths using universal testing machine were measured. Two-way ANOVA and Tukey's test was used (α=0.05). Results: Resin-modified GICs degrade after HCl immersion followed by brushing (p<0.05), while self-cured GICs were negatively affected by all challenges (p<0.05). The challenges decreased the repair strength for VitroFil LC (p<0.05), which had higher repair shear bond strength than the other GICs (p<0.05), exhibiting most cohesive failures. Conclusion: Self-cured GICs degraded when immersed in all acid solutions with brushing while resin-modified GICs only degraded following HCl immersion with brushing. Despite exhibiting the best repair results, VitroFil LC was the only GIC that was influenced by all the acid challenges


Assuntos
Solubilidade , Propriedades de Superfície , Teste de Materiais , Resistência ao Cisalhamento , Cimentos de Ionômeros de Vidro
13.
Oral Dis ; 25(4): 972-981, 2019 May.
Artigo em Inglês | MEDLINE | ID: mdl-29908101

RESUMO

OBJECTIVE: The aim of this systematic review was to compare outcomes between surgical and non-surgical treatment of actinic cheilitis (AC). MATERIALS AND METHODS: A systematic review and meta-analysis based on the Preferred Reporting Items for Systematic reviews and Meta-Analyses guideline were performed. A search of PubMed/MEDLINE, Web of Science, and Cochrane Library databases was conducted. Articles were selected based on the inclusion criteria: randomized clinical trials, prospective/retrospective studies, and case series with at least 10 patients, with a minimum follow-up period of 6 months. A weighted remission rate (RER) and recurrence rate (RR) with a 95% confidence interval was performed. Data analysis was performed using a comprehensive meta-analysis software. RESULTS: A total of 283 ACs in 10 studies were included. About 2.5% surgically treated cases underwent malignant transformation. The weighted remission rate was higher for surgical (92.8%) compared to non-surgical treatment (65.9%). The recurrence rate was lower for surgical (8.4%) compared to non-surgical treatment (19.2%). CONCLUSION: In this systematic review, the surgical treatment was more favorable than non-surgical for AC. Meanwhile, further studies are needed that should maximize methodological standardization and have greater rigor of the data collection process.


Assuntos
Queilite/terapia , Recidiva Local de Neoplasia , Biópsia , Queilite/patologia , Humanos , Estudos Prospectivos , Estudos Retrospectivos , Resultado do Tratamento
14.
Araçatuba; s.n; 2019. 160 p. ilus, tab, graf.
Tese em Português | LILACS, BBO - Odontologia | ID: biblio-1051332

RESUMO

Este projeto teve como objetivo analisar as tensões geradas em próteses implantossuportadas fixa unitária variando o sistema de conexão implante/prótese, o sistema de retenção, material restaurador, tipo ósseo, e o nível de tecido ósseo ao redor do implante através do método dos elementos finitos tridimensionais, e realizar uma revisão sistemática com meta-análise sobre o tema osteoporose em relação a taxa de sobrevivência e perda óssea marginal ao redor dos implantes dentários. Em relação à metodologia experimental, foram simulados 24 modelos tridimensionais com ajuda dos programas de desenho assistido Rhinoceros 3D 4.0 (NURBS Modeling for Windows, USA) e SolidWorks 2011 (SolidWorks Corp, USA), e para confecção da porção óssea será utilizado o programa InVesalius (CTI, São Paulo, Brasil). Cada modelo representou uma secção de osso da região posterior maxilar, na forma de um bloco ósseo tipo IV (normal e osteoporótico), variando o nível de reabsorção do tecido ósseo (a nível do pescoço do implante; perda de 1,5 mm; perda de 3,0 mm; e perda de 4,5 mm) com a presença de um implante de 4,0 mm de diâmetro e 10 mm de comprimento com diferentes tipos de conexão (hexágono externo e cone morse), restaurado com coroas (metalocerâmicas e/ou metal free) com diferentes sistemas de retenção (cimentada e/ou parafusada). Os desenhos tridimensionais foram exportados ao programa de pré e pós processamento FEMAP v.11.2 (Siemens Product Lifecycle Management Software Inc. USA) para geração da malha e aplicação de uma carga de 200N axial e 100N oblíqua (45°) simulando um carregamento nas vertentes internas de cada cúspide da coroa. A análise foi realizada no programa de elementos finitos NEiNastran 11 (Noran Engineering, Inc., EUA) e os resultados serão visualizados através de mapas de tensão von Mises e deslocamento para avaliação das tensões sobre os implantes/componentes e tensão máxima principal, microdeformação e deslocamento para avaliação das tensões no tecido ósseo no tecido ósseo em cada modelo proposto no programa FEMAP v.11.2. Os resultados do capítulo 1, verificaram que a perda do tecido ósseo progressiva apresentou influência na distribuição das tensões na região do tecido ósseo, implantes e componentes. A qualidade do osso afetou apenas os valores de microdeformação, principalmente, no tecido ósseo trabeculado. Os implantes cone Morse apresentaram menores concentrações de tensões na região de tecido ósseo comparado aos implantes de hexágono externo, somente para os modelos sem perda óssea. Os implantes de hexágono externo apresentaram pior comportamento biomecânico nos implantes e parafuso de fixação, principalmente no carregamento oblíquo. Em relação ao capítulo 2 foi possível verificar que os implantes do tipo cone Morse apresentam melhor comportamento biomecânico na região de tecido ósseo cortical e parafuso de fixação em relação aos implantes de hexágono externo em relação as próteses fixas implantossuportadas parafusadas. As próteses cimentadas apresentam uma ligeira redução no tecido ósseo cortical, porém, com maior sobrecarga no parafuso de fixação dos implantes de hexágono externo. Os diferentes materiais restauradores não influenciam no comportamento biomecânico das estruturas. No capítulo 3 após a condução sistematizada das buscas, um total de cinco estudos foram incluídos para tabulação dos resultados. Após a realização da meta-análise foi observado que os implantes dentários devem ser considerados uma alternativa de tratamento viável para a reabilitação de pacientes com osteoporose, porém, cuidados clínicos são necessários aos profissionais para garantir a manutenção da estabilidade óssea periimplantar(AU)


The aim of this thesis was to perform the analysis on the stress distribution for implant-supported fixed prostheses varying the implant-abutment connection system, the fixation system, restorative material, bone type, and the level of bone tissue around the dental implant using the finite element method. Furthermore, the aim was to perform a systematic review and meta-analysis about the effect of osteoporosis in terms of implants survival rate and marginal bone loss. In relation to the experimental methodology, 24 three-dimensional models were simulated with the aid of the Rhinoceros 3D 4.0 (NURBS Modeling for Windows, USA), SolidWorks 2011, and InVesalius (CTI, São Paulo, Brazil) softwares. Each model represented a bone section of the maxillary posterior area (bone type IV) (normal and osteoporotic), varying the level of bone resorption (at the level of the implant, loss of bone tissue in 1.5 mm, loss of bone tissue in 3.0 mm and loss of bone tissue in 4.5 mm). All models containing the presence of a dental implant with 4.0 mm in diameter and 10 mm in length with two different abutment-implant connection (external hexagon and Morse taper), restored with crowns (metaloceramic and/or monolithic) with different fixation system (cemented and/or screwed). The designs were exported to FEMAP v.11.2 pre-and post-processing software (Siemens Product Lifecycle Management Software Inc. USA) for mesh generation and loading application of 200N axial and 100N oblique (45° in the long axis of implant, suppressing lingual cusps) in the slopes each cusp of the crown. The analysis was performed in the NEiNastran 11 (Noran Engineering, Inc., USA) and the results will be imported to FEMAP 11.2 through von Mises stress maps (implants and components) and maximum principal stress and microdeformation (bone tissue). The results of chapter 1 showed that the progressive loss of the bone tissue showed an influence on the stress distribution in the bone tissue, implants and components. The quality of the bone tissue (osteoporosis) affected only the microdeformation, mainly in the trabecular bone tissue. Morse taper implants showed lower stress concentrations in the bone tissue compared to external hexagon implants, only for models without bone loss. The external hexagon implants presented worse biomechanical behavior in the implants and screw fixation, especially in oblique loading. Regarding to chapter 2, it was possible to verify that Morse taper implants showed better biomechanical behavior area of cortical bone tissue and screw fixation compared to external hexagon implants for screwed prostheses. The cemented prostheses showed a slight reduction of stress in the cortical bone tissue; however, with greater stress in the fixation screw for the external hexagon implants. The type of restorative materials (metalceramic and/or monolithic) did not affect the biomechanical behavior of the structures. In chapter 3 after systematic review, a total of five studies were included for tabulation of the data. After performing the meta-analysis it was observed that dental implants should be considered as a viable treatment alternative for the rehabilitation of patients with osteoporosis; however, clinical care is necessary to guarantee the maintenance of peri-implant bone stability, due to high marginal bone loss was observed for patients with osteoporosis(AU)


Assuntos
Estresse Mecânico , Prótese Dentária Fixada por Implante , Fenômenos Biomecânicos , Implantes Dentários , Prótese Dentária , Análise de Elementos Finitos
15.
Braz. dent. j ; 29(4): 342-346, July-Aug. 2018. graf
Artigo em Inglês | LILACS | ID: biblio-974171

RESUMO

Abstract The aim of this is was evaluate the vertical and horizontal marginal adaptation of 3-unit fixed partial denture frameworks fabricated using different techniques and CAD/CAM systems. A total of 40 framework specimens were fabricated and divided into four groups as follows: lost-wax casting (G1); lost-wax casting with welding (G2); extraoral optical scanning of models (3S/DWOS) (G3); intraoral optical scanning (Cerec Bluecam/Sirona) (G4). A reference model was used to simulate a fixed partial denture with three elements (with a central pontic). The frameworks of G1 and G2 were cast in nickel-chromium (NiCr) alloy, whereas those of G3 and G4 were milled in zirconia. In all groups, vertical and horizontal marginal adaptation (over-contour and under-contour) was evaluated using a three-dimensional optical microscope (Quick Scope, Mitutoyo). The results showed higher vertical marginal misfit in G1 than in the other groups (p<0.001). Regarding horizontal marginal misfit, higher over-contour values occurred in G3 than in the other groups (p<0.001). G3 did not show under-contour at all, whereas the other groups did not differ from each other in this regard (p>0.05). Within the limitations of this study, it can be concluded that lost-wax casting with welding is a viable alternative to the use of CAD/CAM systems to fabricate frameworks of three-unit FPDs, since the techniques yielded similar vertical misfit values. Extra-oral CAD/CAM systems showed the highest horizontal misfit (over-contour) compared to other groups.


Resumo O objetivo deste estudo foi avaliar a adaptação marginal vertical e horizontal de infraestruturas de prótese fixas de três elementos confeccionadas por diferentes técnicas e diferentes sistemas CAD/CAM. Um total de 40 infraestruturas foram confeccionadas e divididas em quatro grupos: fundição por cera perdida (G1); fundição por cera perdida com ponto de solda (G2); escaneamento óptico extraoral para escaneamento do modelo (3S/DWOS); escaneamento óptico intraoral (Cerec Bluecam/Sirona) (G4). Uma matriz metálica foi utilizada para simular uma prótese fixa de três elementos (com pôntico central). As infraestruturas do G1 e G2 foram fundidas em liga metálica de níquel-cromo (NiCr), enquanto que as infraestruturas de G3 e G4 foram fresadas em zircônia. Todos os grupos foram analisados quanto à adaptação marginal vertical e horizontal (sobrecontorno e subcontorno) em microscópio óptico tridimensional (Quick Scope, Mitutoyo). Os resultados apresentaram maiores valores de desadaptação marginal vertical no G1 comparados aos outros grupos (p<0,001). Em relação a desadaptação marginal horizontal, maiores valores de sobrecontorno foram observado no G3 em comparação com os demais grupos (p<0,001). Não foi observado valores de subcontorno para o G3, enquanto que os demais grupos não apresentaram diferença significante para o subcontorno (p> 0,05). Dentro das limitações do presente estudo, pode-se concluir que a técnica convencional após ponto de solda é uma alternativa viável para confecção de infraestruturas de próteses fixas de três elementos comparado ao uso de sistemas CAD/CAM, uma vez que as técnicas apresentaram valores de adaptação marginal vertical similares. Os sistemas CAD/CAM extraoral apresentou o maior desajuste horizontal (sobrecontorno) em comparação com outros grupos.


Assuntos
Humanos , Técnica de Fundição Odontológica , Planejamento de Dentadura/métodos , Desenho Assistido por Computador/instrumentação , Adaptação Marginal Dentária , Prótese Parcial Fixa , Materiais Dentários , Modelos Teóricos
16.
Braz. dent. j ; 29(1): 30-35, Jan.-Feb. 2018. tab, graf
Artigo em Inglês | LILACS | ID: biblio-888725

RESUMO

Abstract The purpose of this study was to evaluate different retention systems (cement- or screw-retained) and crown designs (non-splinted or splinted) of fixed implant-supported restorations, in terms of stress distributions in implants/components and bone tissue, by 3-dimensional (3D) finite element analysis. Four 3D models were simulated with the InVesalius, Rhinoceros 3D, and SolidWorks programs. Models were made of type III bone from the posterior maxillary area. Models included three 4.0-mm-diameter Morse taper (MT) implants with different lengths, which supported metal-ceramic crowns. Models were processed by the Femap and NeiNastran programs, using an axial force of 400 N and oblique force of 200 N. Results were visualized as the von Mises stress and maximum principal stress (σmax). Under axial loading, there was no difference in the distribution of stress in implants/components between retention systems and splinted crowns; however, in oblique loading, cemented prostheses showed better stress distribution than screwed prostheses, whereas splinted crowns tended to reduce stress in the implant of the first molar. In the bone tissue cemented prostheses showed better stress distribution in bone tissue than screwed prostheses under axial and oblique loading. The splinted design only had an effect in the screwed prosthesis, with no influence in the cemented prosthesis. Cemented prostheses on MT implants showed more favorable stress distributions in implants/components and bone tissue. Splinting was favorable for stress distribution only for screwed prostheses under oblique loading.


Resumo O objetivo deste estudo foi avaliar diferentes sistemas de retenção (cimentada x parafusada) e configuração da coroas (unitárias x esplintadas) de próteses fixas implantossuportadas em relação a distribuição de tensões nos implantes/componentes e tecido ósseo pela análise de elementos finitos 3D. Quatro modelos 3D foram simulados com auxílio dos programas Invesalius, e Rhinoceros 3D, e SolidWorks. Os modelos foram confeccionados simulando bloco ósseo de região posterior da maxila (tipo ósseo III), com 3 implantes cone Morse com 4,0 mm de diâmetro e diferentes comprimentos, suportando prótese metalocerâmica de 3 elementos. Os modelos foram processados pelos programas FEMAP e NEiNastran sob força axial de 400 N e oblíqua de 200N. Os resultados foram plotados através de mapas de tensão de von Mises (vM) (implantes e componentes) e tensão máxima principal (TMP) (tecido ósseo). Sobre o carregamento axial, não foi observada diferenças entre os diferentes sistemas de retenção e tipo de prótese na distribuição das tensões nos implantes/componentes, porém, sobre o carregamento oblíquo as próteses cimentadas apresentaram melhor distribuição de tensões em comparação com as próteses parafusadas, enquanto que as próteses esplintadas apresentou uma tendência de redução das tensões no implante do primeiro molar. No tecido ósseo as próteses cimentadas apresentaram melhor distribuição das tensões em comparação com as próteses parafusadas, independente do carregamento. A esplintagem foi favorável somente para as próteses parafusadas, não havendo influência sobre as próteses cimentadas. As próteses cimentadas sobre implantes cone Morse apresentam melhor comportamento biomecânico nos implantes/componentes e tecido ósseo. A esplintagem foi efetiva somente nas próteses parafusadas sob carregamento oblíquo.


Assuntos
Humanos , Implantes Dentários , Planejamento de Prótese Dentária , Análise de Elementos Finitos , Maxila/cirurgia , Dente Suporte , Análise do Estresse Dentário
17.
Braz. dent. j ; 29(1): 36-42, Jan.-Feb. 2018. tab, graf
Artigo em Inglês | LILACS | ID: biblio-888728

RESUMO

Abstract The aim of this study was to evaluate the effect of varying the diameter, connection type and loading on stress distribution in the cortical bone for implants with a high crown-implant ratio. Six 3D models were simulated with the InVesalius, Rhinoceros 3D 4.0 and SolidWorks 2011 software programs. Models were composed of bone from the posterior mandibular region; they included an implant of 8.5 mm length, diameter Ø 3.75 mm or Ø 5.00 mm and connection types such as external hexagon (EH), internal hexagon (IH) and Morse taper (MT). Models were processed using the Femap 11.2 and NeiNastran 11.0 programs and by using an axial force of 200 N and oblique force of 100 N. Results were recorded in terms of the maximum principal stress. Oblique loading showed high stress in the cortical bone compared to that shown by axial loading. The results showed that implants with a wide diameter showed more favorable stress distribution in the cortical bone region than regular diameter, regardless of the connection type. Morse taper implants showed better stress distribution compared to other connection types, especially in the oblique loading. Thus, oblique loading showed higher stress concentration in cortical bone tissue when compared with axial loading. Wide diameter implant was favorable for improved stress distribution in the cortical bone region, while Morse taper implants showed lower stress concentration than other connections.


Resumo O objetivo deste estudo foi avaliar o efeito da variação do diâmetro e dos tipos de conexão na distribuição do estresse no osso cortical para implantes com a proporção coroa-implante. Seis modelos 3D foram simulados com os programas InVesalius, Rhinoceros 3D 4.0 e SolidWorks 2011. Os modelos foram compostos de osso da região mandibular posterior. Foram incluídos implantes de 8,5 mm de comprimento, diâmetro Ø 3,75 mm ou Ø 5,00 mm, e tipos de conexão como hexágono externo (EH), hexágono interno (IH) e cone Morse (MT). Os modelos foram processados usando os programas Femap 11.2 e NeiNastran 11.0 e usando uma força axial de 200 N e força oblíqua de 100 N. Os resultados foram registrados em termos da tensão principal máxima. O carregamento oblíquo mostrou alta tensão no osso cortical em comparação com a carga axial. Os resultados mostraram que os implantes com maior diâmetro apresentaram distribuição de tensões mais favorável, independentemente do tipo de conexão, enquanto que os implantes cone Morse apresentaram melhores distribuição de tensões comparado aos outros tipos de conexão, especialmente no carregamento oblíquo. Assim, os implantes de maior diâmetro foram mais favoráveis para distribuição das tensões na região de tecido ósseo cortical, enquanto que os implantes cone Morse apresentam menores concentrações de tensões do que as outras conexões.


Assuntos
Humanos , Implantes Dentários , Análise de Elementos Finitos , Coroas , Estresse Mecânico
18.
Braz. j. oral sci ; 16: e17077, jan.-dez. 2017. ilus
Artigo em Inglês | LILACS, BBO - Odontologia | ID: biblio-884291

RESUMO

Aim: The study aimed to investigate the effect of the association of chemical and mechanical degradation on the surface roughness, gloss and color of nano and microfilled composites. Method: Disc-shaped specimens (n=10) were prepared for three nanocomposites (Filtek Z350XT, IPS Empress Direct, Charisma Diamond) and three microfilled composites (Estelite Σ Quick, Durafill VS, Renamel). After polishing, baseline surface roughness, gloss and color measurements were obtained. Specimens were submitted subsequently to the following challenges: chemical for 1 week (Hydrochloric acid, Coca-Cola and Red Wine) and mechanical (Toothbrushing). Surface roughness and gloss data were analyzed by Kruskal-Wallis followed by Dunn's test. Color difference (ΔE) was analyzed by one-way ANOVA and Tukey test. Results: The initial data were compared with those after challenges using the Wilcoxon test (p<0.05). All composites showed a significant increase (p<0.05) of surface roughness, after overstress. Filtek Z350 XT and Renamel had the lowest final surface roughness values and roughness increase (p<0.05). The comparative analysis revealed that Estelite Σ Quick and Renamel did not significantly change the gloss after challenges (p=0.185). Filtek Z350 XT and IPS Empress Direct had higher color variations, after the challenges than the other resins (p<0.05). Conclusion: Chemical and mechanical challenges influence on characteristics of all composites, except for gloss on Estelite Σ Quick and Renamel composites (AU)


Assuntos
Imersão , Fenômenos Físicos , Resinas Sintéticas , Escovação Dentária
19.
J Photochem Photobiol B ; 169: 83-89, 2017 Apr.
Artigo em Inglês | MEDLINE | ID: mdl-28292696

RESUMO

PURPOSE: This systematic review evaluates the effectiveness of low-level laser therapy (LLLT) to enhance maxillofacial area bone repair. METHODS: A comprehensive search of studies published up to February 2017 and listed in PubMed/MEDLINE, Scopus, and Cochrane Library databases was performed in accordance with the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) statement. RESULTS: The 15 selected studies evaluated a total of 374 patients (mean age, 28.5years) who were treated with LLLT. Gallium-arsenide (GaAs) and gallium aluminium arsenide (GaAlAs) were the most commonly used devices, and LLLT parameters varied greatly. Wavelengths varied from 500 to 1000nm. Tooth extraction, distraction osteogenesis, maxillary expansion, periodontal defects, orthodontic movement and maxillary cystic defects were evaluated. From the 15 selected studies, six evaluated bone repair (primary outcomes). Of these, four studies showed improvement in bone formation after using LLLT, two demonstrated improved results for only one follow up period, and one showed no additional benefits. The other 9 studies evaluated secondary parameters related to healing (secondary outcomes) in the maxillofacial area after applying LLLT, including anti-inflammatory, analgesic, and healing accelerator effects, and quality of life related to oral health. There were no adverse or negative effects of LLLT reported. CONCLUSION: Within the limitation of this review, a possible improvement in bone density can be found when LLLT is applied postoperatively in maxillofacial bony defects. LLLT also seems to promote anti-inflammatory and analgesic effects and accelerate healing, as well as enhance quality of life related to oral health. However, LLLT use protocols need to be standardized before more specific conclusions can be drawn about this subject.


Assuntos
Terapia com Luz de Baixa Intensidade/métodos , Anormalidades Maxilofaciais/terapia , Traumatismos Maxilofaciais/terapia , Adulto , Humanos , Anormalidades Maxilofaciais/patologia , Traumatismos Maxilofaciais/patologia , Osteogênese , Cicatrização
20.
J Craniofac Surg ; 28(4): e381-e383, 2017 Jun.
Artigo em Inglês | MEDLINE | ID: mdl-28328610

RESUMO

The aim of this study was to report a patient of rehabilitation with removable partial denture retained by implants in-patient who suffered injury after firearm shooting. A 19-year-old man presented to the hospital of the Val Paraíso city after being hit by a bullet in the right on the face, affecting the teeth 12 to 16. The surgery to remove the shards of teeth, and bullet was performed. Surgical team opted for installation of implants without bone grafts; however, due to extensive loss of alveolar bone, only 3 tilted implants (2 Ø3.75 × 8.5 mm and 1 Ø3.75 × 10 mm) were installed. After recovery, the patient was referred to the Araçatuba Dental School-UNESP for the rehabilitation on the affected region. The difficulty of rehabilitation with conventional fixed prostheses was verified during the prosthetic phase. This way, it was opted for rehabilitation with removable partial dentures associated with dental implant. Two attachment system ERA (ERA, Sterngold) were positioned in the bar to make the removable partial denture. After 5 years of follow-up, the authors can conclude that the use of removable partial denture retained by implants is effective for functional and aesthetic rehabilitation, favoring socialization and self-esteem of the patient.


Assuntos
Prótese Dentária Fixada por Implante , Prótese Parcial Removível , Maxila , Ferimentos por Arma de Fogo , Adulto , Implantes Dentários , Planejamento de Dentadura , Estética Dentária , Seguimentos , Humanos , Masculino , Maxila/lesões , Maxila/cirurgia , Resultado do Tratamento , Ferimentos por Arma de Fogo/complicações , Ferimentos por Arma de Fogo/reabilitação , Ferimentos por Arma de Fogo/cirurgia
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