Assuntos
Biomarcadores Tumorais/metabolismo , Neoplasias da Mama/metabolismo , Neoplasias da Mama/patologia , Carcinoma/metabolismo , Carcinoma/patologia , Células-Tronco Neoplásicas/patologia , Neoplasias da Mama/diagnóstico , Neoplasias da Mama/genética , Carcinoma/diagnóstico , Carcinoma/genética , Feminino , Regulação Neoplásica da Expressão Gênica , Humanos , Metástase Linfática , Metástase Neoplásica , Inoculação de Neoplasia , Células-Tronco Neoplásicas/metabolismoAssuntos
Anticorpos Monoclonais/uso terapêutico , Antineoplásicos/uso terapêutico , Neoplasias da Mama/tratamento farmacológico , Metformina/uso terapêutico , Anticorpos Monoclonais Humanizados , Neoplasias da Mama/genética , Ensaios Clínicos Fase II como Assunto , Feminino , Humanos , Itália , Terapia Neoadjuvante , Ensaios Clínicos Controlados Aleatórios como Assunto , Receptor ErbB-2/biossíntese , Receptor ErbB-2/genética , Pesquisa Translacional Biomédica , TrastuzumabRESUMO
OBJECTIVE: To report an additional case of collecting duct carcinoma of the kidney, known as carcinoma of Bellini. METHODS/RESULTS: A 65-year-old male patient was admitted for left renal pain. An ultrasound scan showed a solid right renal mass. The patient underwent extended radical nephrectomy. Pathological analysis of the surgical specimen disclosed carcinoma of Bellini. The patient is asymptomatic 18 months postoperatively. CONCLUSIONS: Carcinoma of Bellini is an uncommon tumor type arising from the collecting duct cells and accounts for 0.5%-2% of all renal tumors.
Assuntos
Carcinoma de Células Renais/patologia , Neoplasias Renais/patologia , Túbulos Renais , Idoso , Humanos , MasculinoRESUMO
Report of one case of pure yolk sack testicular tumour in an adult patient. This was a stage I case which had been under observation for 3 years without further evidence of disease. Several aspects related with this type of germinal, non-seminomatous tumour of the testicle are commented upon.
Assuntos
Tumor do Seio Endodérmico , Neoplasias Testiculares , Adulto , Tumor do Seio Endodérmico/patologia , Humanos , Masculino , Neoplasias Testiculares/patologiaRESUMO
A 44-year-old male was diagnosed in August 1980 as having a retroperitoneal germ cell tumor (classic seminoma with anaplastic areas). After treatment with cisplatin-based chemotherapy, he reached complete clinical and pathological remission. Eighty-eight months later, in December 1987, he was diagnosed as having a testicular mixed germ cell tumor (embryonal carcinoma with anaplastic seminoma areas) after right orchiectomy. The potential mechanisms by which the latter tumor could have developed are discussed.