Laryngeal Amyloidosis: What is the Role of Imaging?

OBJECTIVE/HYPOTHESIS: To review the imaging findings of laryngeal amyloidosis and to identify radiological findings suggestive of this disease. STUDY DESIGN: Retrospective case series. METHODS: A retrospective chart review of patients with pathologically confirmed laryngeal amyloidosis was performed from 2009 to 2022. Clinical and demographic factors were collected. A fellowship-trained head and neck radiologist reviewed all computed tomography (CT) scans and magnetic resonance imaging (MRI) findings within this cohort. RESULTS: 12 patients were identified and a total of 36 imaging studies analyzed. Localized amyloidosis was found in the supraglottic region (n = 6), glottic region (n = 7), and subglottic region (n = 5); six patients had disease spanning two subsites. The most common finding on the CT scan was a homogeneous and well-defined submucosal soft tissue mass. Punctate calcifications were present in three cases. The presence of contrast enhancement was identified in the majority of patients who underwent MRI (4/5). MRI showed consistent signal intensity, hypointense, or isointense on both T1-weighted and T2-weighted images. Diffusion-weighted sequences were obtained in every patient and did not demonstrate diffusion restriction. CONCLUSION: This is the largest series searching for unifying imaging characteristics of laryngeal amyloidosis. This research suggests that characteristics from CT and MR provide both similar and unique features of laryngeal amyloidosis on imaging. Both modalities identify a submucosal mass. CT is the preferred modality to demonstrate punctate calcifications, while MRI identifies enhancement and altered signal characteristics. The main benefit of serial imaging is the correlation with patient symptoms, identification of the extent of disease, and assisting in delineating appropriate timing for surgery.

Acquired butterfly vertebra as a sequela of eosinophilic granuloma.

Butterfly vertebras are an abnormal embryological formation of the spinal bodies that occur because of a lack of fusion of the chondrification centers of the vertebral bodies. Langerhans cell histiocytosis is an entity that frequently involves vertebral bodies resulting in flat vertebras, and recovery of the vertebral body height is a very unusual finding. We present a case report of a pediatric patient with a thoracic acquired butterfly vertebra which occurred secondary to a Langerhans cell histiocytosis involvement. It is extremely rare to find vertebra plana that regains its complete height but is even more infrequent to evidence of a butterfly vertebra deformity that is not congenital.

Cystic trigeminal schwannomas.

Trigeminal Schwannomas are less than 1% of intracranial tumors, of which only 7% have a cystic component. We documented 2 cases of males with cystic trigeminal Schwannomas, their symptoms, the diagnosis process and the imaging characteristics. In addition, a review of the literature is performed, with emphasis on the radiological classification of this rare entity, that constitutes a diagnostic challenge for the radiologist, who has an essential role in the approach to the disease and therefore in its management.

Conocimientos, actitudes y aceptación de la sal fluorada en una población peruana / Knowledge, attitudes and acceptance of fluoridated salt in a peruvian population

Determinar los conocimientos, actitudes y aceptación de la sal fluorada de los padres de familia atendidos en la Casa del Adulto Mayor y la Casa de la Mujer de la Municipalidad de Chorrillos. Lima û Perú. Materiales y métodos. La muestra estuvo conformada por 130 padres de familia. Se realizó una entrevista estructurada y se presentaron los datos mediante tablas de distribución de frecuencias. Resultados. Respecto al conocimiento sobre la sal fluorada, solo el 16,2% conocía de su existencia, y de este grupo, el 33,3% no estaba informado de sus beneficios. Respecto a las actitudes sobre la sal fluorada, el 76,9% refirió que no compraba ninguna marca en especial. La mayor parte no revisaba la etiqueta o leía solo la marca para identificar la sal de su elección (45,4% en ambos casos). El 86,9% manifestó no saber si vende sal fluorada cerca de su casa. Respecto a la aceptación, el 91,6% estaba de acuerdo con que la eficacia en la prevención de la caries es una buena razón para su consumo. El 97,7% consideró que los beneficios de la sal fluorada deberían darse a conocer en la etiqueta de la bolsa. El 93,1% estaría dispuesto a utilizar diariamente la sal fluorada en la preparación de las comidas de los niños, y el 96,2% recomendaría su uso a otros padres de familia. Conclusiones. La mayor parte de la población no presenta un conocimiento adecuado sobre la sal fluorada. Sin embargo, estarían dispuestos a consumirla y recomendarla si estuviesen mejor informados sobre los beneficios que aporta...

Objective. To determine the knowledge, attitudes and acceptance of the fluoridated salt of parents attended in the House of the Older Adult and the House of the Women, Municipality of Chorrillos. Lima - Peru. Material and methods. The sample consisted of 130 parents. An structured survey was made and data was presented by frequency distribution tables. Results. Regarding knowledge about fluoride salt, 16.2% knew of its existence. Of this group, 33.33% was not inofremed about their benefits. Regarding attitudes about fluoridated salt, 76.9% reported that they did not buy any brand in particular. The majority did not check the label or read only the mark to identify the salt of your choice (45.4% in both cases). 86.9% said that it did not know if they sell this productnear his home. With respect to the acceptance, 91.6% was in agreement with the effectiveness of caries prevention is a good reason for consumption. 97.7% considered the benefits of fluoridated salt should be disclosed in the label on the bag. 9.1% were willing to use fluoridated salt dialy to prepare meals for the children, and 96.2% would recommend its use to other parents Conclusions. The majority of the population does not have an adequate knowledge about the fluoridated salt. However, they would be willing to consume it and recommend it if they were better informed about the benefits...