Precocious puberty in the McCune-Albright syndrome. Progression from gonadotrophin-independent to gonadotrophin-dependent puberty in a girl.

A 5-year-old girl with McCune-Albright syndrome, was observed over a 7-year period. She presented with gonadotrophin-independent puberty and later developed gonadotrophin-dependent puberty. Hormonal signs of central puberty remained unchanged over the last 2 years.