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1.
Palliat Med ; 38(4): 492-497, 2024 Apr.
Artigo em Inglês | MEDLINE | ID: mdl-38444061

RESUMO

BACKGROUND: Seizures are an important palliative symptom, the management of which can be complicated by patients' capacity to swallow oral medications. In this setting, and the wish to avoid intravenous access, subcutaneous infusions may be employed. Options for antiseizure medications that can be provided subcutaneously may be limited. Subcutaneous sodium valproate may be an additional management strategy. AIM: To evaluate the published experience of subcutaneous valproate use in palliative care, namely with respect to effectiveness and tolerability. DESIGN: A systematic review was registered (PROSPERO CRD42023453427), conducted and reported according to PRISMA reporting guidelines. DATA SOURCES: The databases PubMed, EMBASE and Scopus were searched for publications until August 11, 2023. RESULTS: The searches returned 429 results, of which six fulfilled inclusion criteria. Case series were the most common study design, and most studies included <10 individuals who received subcutaneous sodium valproate. There were three studies that presented results on the utility of subcutaneous sodium valproate for seizure control, which described it to be an effective strategy. One study also described it as an effective treatment for neuropathic pain. The doses were often based on presumed 1:1 oral to subcutaneous conversion ratios. Only one study described a local site adverse reaction, which resolved with a change of administration site. CONCLUSIONS: There are limited data on the use of subcutaneous sodium valproate in palliative care. However, palliative symptoms for which subcutaneous sodium valproate have been used successfully are seizures and neuropathic pain. The available data have described few adverse effects, supporting its use with an appropriate degree of caution.


Assuntos
Anticonvulsivantes , Cuidados Paliativos , Ácido Valproico , Humanos , Ácido Valproico/uso terapêutico , Anticonvulsivantes/uso terapêutico , Anticonvulsivantes/administração & dosagem , Convulsões/tratamento farmacológico , Injeções Subcutâneas , Feminino , Idoso , Masculino , Pessoa de Meia-Idade , Adulto , Idoso de 80 Anos ou mais
3.
J Palliat Care ; 21(2): 80-7, 2005.
Artigo em Inglês | MEDLINE | ID: mdl-16114806

RESUMO

This article presents results of the second stage of a research project which explored the palliative care needs of 69 residents with a noncancer diagnosis in South Australia. Extensive data were collected prospectively from case notes, and resident and staff interviews over a 10-week period. Residents were suffering multiple conditions and were highly dependent for activities of daily living. Most residents' care was consistent with a palliative approach, with only three residents in the study referred to a specialist palliative care service. However, for some residents, pain and symptom management were not always adequate, and referral to a specialist palliative care service would have been appropriate. This research indicates that, with additional education, it could be possible to extend the principles and philosophy of palliative care by adopting a palliative care approach within aged care facilities.


Assuntos
Doença Crônica , Necessidades e Demandas de Serviços de Saúde , Instituição de Longa Permanência para Idosos/organização & administração , Medicina , Cuidados Paliativos/métodos , Especialização , Idoso , Idoso de 80 Anos ou mais , Feminino , Saúde Holística , Humanos , Masculino , Medição da Dor , Autonomia Pessoal , Qualidade de Vida , Encaminhamento e Consulta , Austrália do Sul
4.
Aust N Z J Public Health ; 29(1): 85-90, 2005 Feb.
Artigo em Inglês | MEDLINE | ID: mdl-15782878

RESUMO

OBJECTIVE: This research examined the provision of palliative care for residents with a non-cancer diagnosis including the use of advance directives and advance care planning as part of palliative care policies in residential aged care facilities in South Australia. There are no guidelines for recording residents' wishes if they are no longer competent. METHODS: Stage 1 involved a survey of 90 randomly selected aged care facilities. Stage 2 involved case studies of 69 residents, appropriate for palliative care, from 17 facilities and interviews with 15 directors of care. RESULTS: Most residential aged care facilities used forms to record residents' wishes about end of life care, but there was little consistency. Some had no palliative care policy and few facilities required a formal advance directive. Not all residents had formally appointed a proxy. CONCLUSIONS: Residential aged care facilities should be required to develop and implement a palliative care policy acknowledging the Accreditation Standards and State legislation and including a simple tool for advance care planning. Case conferencing could assist in discussing and documenting the resident's wishes. Public education is essential to increase community and professional awareness in order to promote empowerment for the increasing number of older people who will die in residential aged care facilities.


Assuntos
Diretivas Antecipadas/tendências , Atitude Frente a Morte , Instituição de Longa Permanência para Idosos , Cuidados para Prolongar a Vida/normas , Ordens quanto à Conduta (Ética Médica) , Instituições de Cuidados Especializados de Enfermagem , Planejamento Antecipado de Cuidados , Documentação , Feminino , Pesquisa sobre Serviços de Saúde , Humanos , Cuidados para Prolongar a Vida/tendências , Masculino , Cuidados Paliativos/estatística & dados numéricos , Sensibilidade e Especificidade , Austrália do Sul
5.
Palliat Support Care ; 3(1): 5-14, 2005 Mar.
Artigo em Inglês | MEDLINE | ID: mdl-16594189

RESUMO

OBJECTIVE: To identify criteria for measuring the eligibility of patients with end-stage noncancer diseases for palliative care services in Australian residential aged care facilities. METHODS: No validated set if guidelines were available so five instruments were used: an adaptation of the American National Hospice Association Guidelines; a recent adaptation of the Karnofsky Performance Scale; the Modified Barthel Index; the Abbey Pain Score for assessment of people who are nonverbal and a Verbal Descriptor Scale, also for pain measurement. In addition, nutritional status and the presence of other problematic symptoms and their severity were also sought. RESULTS: The adapted American National Hospice Association Guidelines provided an initial indicative framework and the other instruments were useful in providing confirmatory data for service eligibility and delivery.


Assuntos
Definição da Elegibilidade/estatística & dados numéricos , Cuidados Paliativos na Terminalidade da Vida/estatística & dados numéricos , Avaliação das Necessidades/estatística & dados numéricos , Cuidados Paliativos/estatística & dados numéricos , Austrália , Estado Terminal/enfermagem , Necessidades e Demandas de Serviços de Saúde/estatística & dados numéricos , Humanos
6.
Med J Aust ; 179(S6): S4-5, 2003 09 15.
Artigo em Inglês | MEDLINE | ID: mdl-12964924
7.
Med J Aust ; 179(S6): S6-7, 2003 09 15.
Artigo em Inglês | MEDLINE | ID: mdl-12964925

RESUMO

Bereavement support is an integral part of palliative care. Grieving after loss is a normal process; however, some grief reactions become complicated and may seriously compromise the health of an individual. Routine bereavement care helps identify people at risk of complicated grieving. The burden of grief can last for years, sometimes indefinitely. People caring for the bereaved need to pay special attention to cultural differences, the burden of caring for dying children, and the special support needs of bereaved children and adolescents. Excellent resources to assist in grief management, including the expertise of palliative care teams, are readily available.


Assuntos
Luto , Cuidados Paliativos , Pesar , Humanos , Apoio Social
8.
Med J Aust ; 179(S6): S17-9, 2003 09 15.
Artigo em Inglês | MEDLINE | ID: mdl-12964929

RESUMO

All Indigenous communities in Australia have a common heritage of loss. Indigenous death rates are much higher than those for white Australians. Indigenous people use healthcare services reluctantly, and palliative care services rarely. Cultural considerations that need to be respected include Indigenous understandings of disease causation, attributions of blame for sickness, the performance of ceremonies after death and the importance of dying on traditional lands. The involvement of Indigenous health workers in clinical care increases confidence in the healthcare system as a whole.


Assuntos
Cultura , Havaiano Nativo ou Outro Ilhéu do Pacífico , Cuidados Paliativos , Atitude Frente a Morte , Austrália , Tomada de Decisões , Humanos , Havaiano Nativo ou Outro Ilhéu do Pacífico/psicologia
9.
J Pain Palliat Care Pharmacother ; 17(3-4): 211-21, 2003.
Artigo em Inglês | MEDLINE | ID: mdl-15022964

RESUMO

Individuals who have experience in palliative care in wealthier countries with well-structured health systems see the palliative care needs of developing countries as forbiddingly huge. They are aware of an increasing incidence of cancer, but health delivery systems are often patchy and deficient, medications for pain management are not widely available, and cultural considerations limit opportunities to face advanced illness and focus on symptom control in terminal illness. An increasing prevalence of HIV infection compounds palliative care needs. Medical practice focuses on interventions that promise cure and earn a good reward, while nursing standards are variable and often unsatisfactory. There is a need for demonstrations of good care and effective symptom control, even if these reach only a small fraction of the needy population. On such demonstrations can be built education programs that take account of local realities, and promote attitudes, knowledge and skills capable of gradually introducing a greater professional concern and a better prospect of effective care for the dying.


Assuntos
Países em Desenvolvimento , Educação em Enfermagem , Pessoal de Saúde/educação , Dor/tratamento farmacológico , Cuidados Paliativos , Síndrome da Imunodeficiência Adquirida/epidemiologia , Síndrome da Imunodeficiência Adquirida/enfermagem , Síndrome da Imunodeficiência Adquirida/fisiopatologia , Analgésicos Opioides/uso terapêutico , Atitude Frente a Morte/etnologia , Atitude Frente a Saúde/etnologia , Educação Baseada em Competências , Pessoal de Saúde/psicologia , Necessidades e Demandas de Serviços de Saúde , Humanos , Neoplasias/epidemiologia , Neoplasias/enfermagem , Neoplasias/fisiopatologia , Dor/etiologia , Dor/enfermagem , Apoio ao Desenvolvimento de Recursos Humanos , Recursos Humanos
10.
Drugs Aging ; 19(7): 495-502, 2002.
Artigo em Inglês | MEDLINE | ID: mdl-12182686

RESUMO

Palliative care has been slow to demonstrate that its common interventions are supported by high levels of evidence. There are multiple reasons for this--historical and cultural, as well as the recognised difficulties of conducting studies in dying persons. There are problems in isolating the effect of a single intervention from the many other changing dimensions which attend the progress of terminal illness, and problems also in defining particular outcomes free from the contaminating effect of other simultaneous changes in a patient's situation. Sickness is an interaction between disease and patient, and science sits more comfortably with the study of disease than with the understanding of the patient. Nevertheless, the therapies commonly employed for symptom management in individuals with advanced and terminal illness deserve more rigorous investigation to establish their efficacy. In Australia, new levels of government support for research have stimulated a closer examination of principles and practical guidelines for the conduct of research in this area of healthcare.


Assuntos
Ensaios Clínicos como Assunto , Cuidados Paliativos , Idoso , Austrália , Humanos , Projetos de Pesquisa , Resultado do Tratamento
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