Robotic-assisted Total Knee Arthroplasty Technology Provides a Repeatable and Reproducible Method of Assessing Soft Tissue Balance.

Soft-tissue balancing is an important factor in primary total knee arthroplasty (TKA), with 30 to 50% of TKA revisions attributed to technical operative factors including soft-tissue balancing. Robotic-assisted TKA (RATKA) offers opportunities for improved soft-tissue balancing methods. This study aimed to evaluate the repeatability and reproducibility of ligamentous laxity assessments during RATKA using a digital tensioner.Three experienced RATKA surgeons assessed preresection and trialing phases of 12 human cadaveric knees with varying degrees of arthritis. Ligamentous laxity was assessed with manual varus and valgus stresses in extension and flexion, with a digital tensioner providing feedback on the change of laxity displacement. Intraclass correlation coefficient (ICC) analyses were used to determine the repeatability within a single surgeon and reproducibility between the three surgeons.The results showed excellent repeatability and reproducibility in ligamentous laxity assessment during RATKA. Surgeons had excellent repeatability for preresection and trialing assessments, with median ICC values representing excellent reproducibility between surgeons. Surgeons were repeatable within 1 or 1.5 mm for preresection and trialing assessments. On average, the variation within a surgeon was 0.33 ± 0.26 mm during preresection and 0.29 ± 0.28 mm during trialing. When comparing surgeons to each other, they were reproducible within an average of 0.69 ± 0.33 mm for preresection and 0.65 ± 0.31 mm for trialing.This study demonstrated the reliability of robotic-assisted soft-tissue balancing techniques, providing control over ligamentous laxity assessments, and potentially leading to better patient outcomes. The digital tensioner used in this study provided excellent repeatability and reproducibility in ligamentous laxity assessment during RATKA, highlighting the potential benefits of incorporating robotics in TKA procedures.

Mid-Term Performance of the First Mass-Produced Three-Dimensional Printed Cementless Tibia in the United States as Reported in the American Joint Replacement Registry.

BACKGROUND: Cementless tibial components have shown improvements in clinical performance compared to predicate designs, though evidence supporting mid-term performance and fixation is scarce. The purpose of this study is to determine the mid-term survivorships, revision rates, and reasons why 3-dimensional printed cementless tibial baseplates (3DTKAs) failed compared to other cementless as well as cemented tibial baseplates reported from the American Joint Replacement Registry (AJRR) data. METHODS: All primary total knee arthroplasty (TKA) cases performed in patients 65 years of age or older within the AJRR from January 2, 2012 through June 30, 2020 were queried. A total of 28,631 3DTKAs were identified from 428 institutions. These were compared to all other "aggregated cementless tibia" (n = 7,577) and "aggregated cemented tibia" (n = 550,133) cases. Centers for Medicare & Medicaid Services data over the same time period were merged with AJRR data to determine survivorship and patient-timed incident revision rates per 1,000 years. Failure reasons were tracked during this study period. RESULTS: At 60 months, Kaplan-Meier implant survivorship was 98.9% (CI 98.7-99.0), 98.3% (CI 97.9-98.6), and 98.4% (CI 98.4-98.5) in the 3DTKA, aggregate cementless, and cemented knee cohorts, respectively (P < .0001). Patient-timed incident revision rates were 3.11 (CI 2.75-3.53), 3.99 (CI 3.34-4.76), and 3.35 (CI 3.28-3.42) for those cohorts, which corresponds to a revision rate of 0.31%, 0.40%, and 0.34% per year. CONCLUSION: In this analysis, 3DTKA had favorable survivorship and lower revision rates compared to aggregate cementless and cemented TKAs implanted from the same national database during the same time period.

Increased Prevalence of Posterior Cruciate Ligament Dysfunction Noted With 3-Dimensional Intraoperative Kinematic Evaluation in Total Knee Arthroplasty.

BACKGROUND: Poor restoration of cruciate-driven kinematics after total knee arthroplasty may result from technical difficulties, but the ligament may also be functionally compromised by the presence of arthritis. We asked whether the function of the posterior cruciate ligament (PCL) could be assessed intraoperatively to predict the quality of the resulting posterior cruciate kinematics. METHODS: PCL integrity was assessed using intraoperative infrared trackers to monitor knee kinematics in 73 patients. Three-dimensional images of the femur and tibia were projected onto a screen, allowing the surgeon to visualize kinematic relationships in real time. We measured femoral rollback (distance of femoral contact as a percentage of antero-posterior tray width) from images captured by the robotic system during initial kinematic assessment, gap balancing, and assessment of the final construct and from lateral flexion radiographs obtained 2 years after surgery. Associations were characterized using Pearson's correlation and graphical methods. RESULTS: Thirty-six knees (49%) showed rollback <60% during gap balancing, indicative of PCL insufficiency. The rollback during gap balancing was positively correlated with that seen in the final cruciate retaining constructs (r = 0.60, P < .001), which in turn predicted rollback 2 years after surgery on lateral flexion X-rays (r = 0.50, P = .006). CONCLUSION: Intraoperative functional evaluations can allow the surgeon to identify cases where rollback is not consistent with desirable knee kinematics, and posterior stabilization may lead to a better outcome for those patients.

Patient-Reported Functional and Satisfaction Outcomes after Robotic-Arm-Assisted Total Knee Arthroplasty: Early Results of a Prospective Multicenter Investigation.

The purpose of this study was to perform a 3-month interim comparative analysis on outcomes between robotic-arm-assisted total knee arthroplasty (RATKA) and manual TKA patients. Specifically, we evaluated (1) patient self-reported symptoms, (2) expectations and satisfaction, and (3) functional activities, based on the 2011 Knee Society Scoring System. Between June 1, 2016, and March 31, 2018, 252 patients (102 manual and 150 robotic) were enrolled into a prospective, nonrandomized, open-label, multicenter comparative cohort study. Functional activity scores, patient-reported symptoms, as well as satisfaction and expectation scores were obtained from the 2011 Knee Society Scoring System preoperatively, at 4 to 6 weeks, and at 3 months postoperatively. Student's t-tests, Wilcoxon rank-sum tests, and chi-square tests with α set at 0.05 were used to compare between-group mean improvements from baseline. At 4 to 6 weeks postoperatively, RATKA patients were found to have significantly larger improvements in walking and standing (1.4 vs. -1.2 points; p = 0.019). RATKA patients were also found to have larger improvements in advanced activities (1.3 vs. 2.3 points), pain with walking (3.3 vs. 3.2 points), satisfaction score (12.4 vs. 12 points), and expectations score (5.1 vs. 4.4 points) when compared with manual TKA patients. At 3 months, RATKA patients were also found to have larger improvements in walking and standing (6.0 vs. 4.8 points), standard activities (11.4 vs. 10.1 points), advanced activities (6.2 vs. 4.6 points), functional activities total score (22.8 vs. 21.2 points), pain with walking (4.3 vs. 4.1 points), total symptoms score (10.5 vs. 10.3 points), satisfaction score (17.0 vs. 15.5 points), expectations score (4.8 vs. 4.0 points) when compared with manual TKA patients. The data indicate RATKA patients to have equal or greater improvements in 9 out of 10 of the Knee Society Scoring System components assessed at 3 months postoperatively, though not all findings were statistically significant. Since this is an early results report, this study will be continued for a longer follow-up, but we are encouraged by these interim results.

Disease Progression After Lateral and Medial Unicondylar Knee Arthroplasty.

BACKGROUND: Medial unicompartmental knee arthroplasty (UKA) has been a successful option for treatment of arthritis in patients with a healthy lateral compartment. However, lateral UKA is less common and results are less consistent. The purpose of this study is to compare progression of radiographically evident osteoarthritis in unoperated compartments during 5 years after lateral and medial UKA. METHODS: We undertook serial radiographic evaluation of 20 lateral and 114 medial UKA performed by the senior author during calendar years 2007-2008. Anteroposterior, lateral, and skyline radiographs obtained preoperatively and 1 and 5+ (mean, 5.3; range, 5.1-6.4) years postoperatively were independently graded for osteoarthritis in the unoperated tibiofemoral (TF) and patellofemoral (PF) compartments using established scales of Kellgren (0-4 point global scale for osteoarthritis), Ahlbäck (0-5 point scale based on joint space narrowing), and Altman (0-12 point composite criteria score). Rates of disease progression were compared between lateral and medial UKA groups using bivariate methods and multilevel growth models that adjusted for baseline characteristics. RESULTS: All mean disease grades for the TF and PF compartments increased (worsened) over time. The adjusted rate of Kellgren grade change was statistically (P < .05) faster for lateral UKA in the TF and PF compartments, as was Ahlbäck change in the TF compartment. Kellgren grade for the TF compartment of lateral and medial UKA groups increased 1.1 vs 0.6 points on average over 5 years adjusted for age, sex, and body mass index (P < .001). CONCLUSION: Surgeons should consider the propensity for faster disease progression after UKA in evaluating patients with isolated lateral compartment disease. LEVEL OF EVIDENCE: Level III, therapeutic study.

Knee strength, power and stair performance of the elderly 5 years after unicompartmental knee arthroplasty.

BACKGROUND: Unicompartmental knee arthroplasty (UKA) has been shown to demonstrate some satisfactory short-term outcomes. However, to our knowledge, there have been no reports on midterm or long-term knee extensor strength and leg extensor power post-UKA. AIMS: Therefore, the purposes of this study were: (1) to assess the isokinetic knee extensor strength, leg extensor power and stair performance of elderly participants at 5 years UKA post-operation; (2) to compare the differences in knee extensor strength and leg extensor power between the UKA and contralateral healthy limbs. METHODS: Nineteen elderly participants (75 ± 5 years) who had a medial or a lateral compartment UKA at 5 years post-operation were recruited. The isokinetic knee extensor strength and leg extensor power were measured. The stair performance was tested on a 4-step stair, and ascent and descent velocities were calculated. The pain level was assessed. RESULTS: The UKA limbs' knee extensor strength and leg extensor power were 1.01 ± 0.39 Nm/kg and 0.98 ± 0.27 W/kg, respectively. The stair ascent and descent velocities were 0.37 ± 0.07 and 0.38 ± 0.11 m/s, respectively. In addition, the UKA limbs exhibited comparable knee strength and leg power relative to the contralateral limbs. DISCUSSION: In general, the knee extensor strength and leg extensor power exhibited by the UKA limbs at 5 years post-operation may be typical in comparison with the normative data. CONCLUSIONS: We suggest that UKA is a satisfactory treatment in regard to the recovery of knee strength, leg power and ability to climb up and down stairs.

Balanced Flexion and Extension Gaps Are Not Always of Equal Size.

BACKGROUND: It has been widely accepted in total knee arthroplasty (TKA) that flexion and extension gaps in the disarticulated knee during surgery should be equalized. We hypothesized that tensioning during assessment of the flexion gap can induce temporary widening of the gap due to posterior tibial translation. We aimed to describe posterior tibial translation at flexion gap (90°) assessments and assess the correlation of tibial translation with laxity (flexion space increase) using constrained and non-constrained inserts. METHODS: Imageless navigation was used to measure flexion angle, tibial position relative to the femoral axis, and lateral/medial laxity in 30 patients undergoing primary TKA. Trialing was conducted using posteriorly stabilized and cruciate retaining trials of the same size to elucidate the association of posterior tibial translation with changes in joint capsule laxity at 90° knee flexion. RESULTS: All patients demonstrated posterior tibial translation during flexion gap assessment relative to their subsequent final implantation [mean ± standard deviation (range), 11.3 ± 4.4 (4-21) mm]. Positive linear correlation [r = 0.69, 95% confidence interval (CI) 0.44-0.84, P ≤ .001] was demonstrated between translations [8.7 ± 2.4 (3-13) mm] and laxity changes [2.9° ± 2.0° (-0.7° to 7.4°)] at 90° of flexion. CONCLUSION: Posterior tibial translation can cause artifactual widening of the flexion gap during gap balancing in posteriorly stabilized TKA, which can be of sufficient magnitude to alter femoral component size selection for some patients. Recognition and management of these intra-operative dynamics for optimal kinematics could be feasible with the advent of robotic applications.

Cementation of tibial inserts into nonmatching base plates in revision total knee arthroplasty.

UNLABELLED: We describe the use of a novel technique for adapting nonmatching tibial inserts into tibial trays in revision total knee arthroplasty. From 1998 to 2003, the senior author performed 7 revision total knee arthroplasty procedures, during which a nonmatching tibial insert was cemented into a tibial tray to retain a well-fixed but incompatible opposite component. Bench tests were undertaken to confirm the stability of cement as a locking mechanism substitute. Three components completed 1 000 000 cycles of loading under simulated physiologic stresses with no evidence of fixation failure. There have been no clinical failures at 18 to 69 months in vivo follow-up (mean, 49 months). This technique provided durable fixation while avoiding host bone damage that might have occurred needlessly had the well-fixed implant been extracted. LEVEL OF EVIDENCE: level IV therapeutic study, case series.

Overhang of the femoral component in total knee arthroplasty: risk factors and clinical consequences.

BACKGROUND: Recently, much attention has been directed to femoral component overhang in total knee arthroplasty. The purposes of this study were to describe the prevalence of femoral component overhang among men and women after total knee arthroplasty, to identify risk factors for overhang, and to determine whether overhang was associated with postoperative knee pain or decreased range of motion. METHODS: Femoral component overhang was measured intraoperatively during 437 implantations of the same type of total knee arthroplasty prosthesis. The overhang of metal beyond the bone cut edge was measured in millimeters at the midpoint of ten zones after permanent fixation of the implant. Factors predictive of overhanging fit were identified, and the effect of overhang on postoperative pain and flexion was examined. RESULTS: Overhang of >or=3 mm occurred in at least one zone among 40% (seventy-one) of 176 knees in men and 68% (177) of 261 knees in women, most frequently in lateral zones 2 (anterior-distal) and 3 (distal). Female sex, shorter height, and larger femoral component size were highly predictive of greater overhang in multivariate models. Femoral component overhang of >or=3 mm in at least one zone was associated with an almost twofold increased risk of knee pain more severe than occasional or mild at two years after surgery (odds ratio, 1.9; 95% confidence interval, 1.1 to 3.3). CONCLUSIONS: In this series, overhang of the femoral component was highly prevalent, occurring more often and with greater severity in women, and the prevalence and magnitude of overhang increased with larger femoral component sizes among both sexes. Femoral component overhang of >or=3 mm approximately doubles the odds of clinically important knee pain two years after total knee arthroplasty.

Durable fixation with a modern fully hydroxylapatite-coated long stem in complex revision total hip arthroplasty.

We describe the use of a fully hydroxylapatite-coated long-stem femoral implant in a series of 40 complex revision total hip arthroplasties. All reconstructions involved severe bone loss or malalignment and were accomplished entirely without the use of augmentary bone graft. Outcomes were evaluated at 7 minimum years of follow-up (average, 10.2 years). Three stems were rerevised because of infection, trauma, and loosening with nonunion of a fracture. Bone ingrowth was radiographically evident by one postoperative year in all other cases. There were no cases of subsidence. Stress shielding with thigh pain was seen in one patient. The stem provided immediate stability and excellent long-term fixation in these reconstructions of severely diseased femurs.

5- to 9-year survivorship of single-radius, posterior-stabilized TKA.

UNLABELLED: We studied 1030 consecutive cemented primary TKAs performed by the primary author (OMM) using a single-radius, posterior-stabilized total knee prosthesis with 5 years' minimum followup to determine whether an accelerated early failure rate was associated with this design. At 5 to 9.5 postoperative years, 32 knees had been revised at an average of 2.4 postoperative years (range, 0.1-8.2 years) because of infection (11), periprosthetic fracture (10), aseptic loosening (eight), stiffness (two), and late hemarthrosis (one). Four had only the tibial insert revised. One-half of all failures occurred within 1.5 years. The cases of aseptic loosening involved the femoral component in one patient, tibial component in five, and both components in two. With only seven patients (0.7%) having unknown outcomes, the overall failure rate was 4.9 per 1000 person-years for the study period. The Kaplan-Meier survivorship using any part of the prosthesis removed or revised for any reason as the end point was 95.8% (95% confidence interval, 93.7%-95.5%), and with aseptic loosening as the end point, it was 98.6% (95% confidence interval, 96.5%-99.4%). The midterm survivorship rates were comparable to those of other posterior-stabilized total condylar designs and are not suggestive of excessive risk of early failure. LEVEL OF EVIDENCE: Level IV, therapeutic study. See the Guidelines for Authors for a complete description of levels of evidence.

Modular insert exchange in knee arthroplasty for treatment of wear and osteolysis.

UNLABELLED: Wear and osteolysis have been successfully treated by modular polyethylene exchange in revision hip arthroplasty. However, studies of the same approach in revision knee arthroplasty have not provided similar results. We evaluated the results of isolated polyethylene exchange for wear and/or osteolysis in 68 press-fit condylar TKAs from four centers. At a minimum of 24 months after polyethylene exchange surgery (average, 44 months; range, 24-83 months), there were 11 failures (16.2%). Failures included aseptic loosening in 10 knees and infection in one. With the relatively small cohort size we were unable to identify factors that predicted which knees were more likely to fail: we observed no correlation between failure and patient demographics, component design, or use of cement versus bone graft augmentation. Radiographic review demonstrated no progression of osteolytic lesions in 97% of knees in the study. While the short-term followup limits the conclusions, we believe the 84% success rate with modular polyethylene exchange for wear and osteolysis and the lack of progression of osteolytic lesions in the majority of the knees are encouraging. Full revision of well-fixed total knee components can lead to substantial bone loss, particularly in the face of osteolysis and we therefore consider modular polyethylene exchange in press-fit condylar knees a reasonable option for wear and osteolysis. LEVEL OF EVIDENCE: Level IV, therapeutic study. See the Guidelines for Authors for a complete description of levels of evidence

Two-year experience using a limited-incision direct lateral approach in total hip arthroplasty.

We evaluated clinical, radiographic, and short-term recovery outcomes in an 18-month 1 surgeon series of 102 unilateral primary total hip arthroplasties performed by direct lateral approach through standard size (15-20 cm) and limited (<10 cm) incisions. Patients were blinded to incision type. Observed measures related to hematological status, transfusions, operative time, hospitalization time, narcotic use, rehabilitation, and discharge disposition did not appear to differ by incision type. Components were well placed in both groups. Intraoperative femoral fractures occurred in 2 limited-incision cases. At 2 years' minimum follow-up, we did not observe evidence that minimally invasive surgical technique provided clinically significant benefit to these patients.

Modular femoral offset stems facilitate joint line restoration in revision knee arthroplasty.

UNLABELLED: Restoration of proper joint line position in revision total knee arthroplasty is essential in promoting recovery of function. We retrospectively analyzed joint line restoration and clinical outcomes in 22 consecutive femur revision cases using modular offsets of variable length and direction between the intramedullary fixation rod and the femoral component. Flexion and extension gap balancing techniques and medial epicondylar referencing was used to achieve proper position of the joint line. Position of the reconstructed joint line from postoperative radiographs was compared to the baseline position of intended anatomic placement determined from pre-operative planning radiographs. Postoperative joint line height averaged 1.6 mm distal to baseline (range, 5 mm distal to 2.5 proximal). Joint line was restored to within 2 mm of anatomic position in 12 of the 22 knees. Sixteen patients received conventional, minimally constrained tibial inserts, and joint stability was achieved in all cases. LEVEL OF EVIDENCE: Therapeutic study, Level IV (case series). See Guidelines for Authors for a complete description of levels of evidence.