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1.
BMC Cancer ; 20(1): 1078, 2020 Nov 10.
Artigo em Inglês | MEDLINE | ID: mdl-33167928

RESUMO

BACKGROUND: In low-income countries breast cancer awareness (BCA) is essential to reduce the proportion of advanced stage presentations of breast cancer. There is a lack of studies using multivariable techniques to explore factors related to BCA in low-income countries. The objective of this study was to identify to what extent women in Fiji and Kashmir, India have BCA and practice breast self-examination (BSE) as well as factors associated with BCA and BSE. METHODS: A survey of women aged ≥18 years was conducted in Fiji and Kashmir, India to assess BCA and rates of BSE. Comparison between Fiji and Kashmir was done using student's t-test for continuous data and chi-square for binary data. Factors associated with BCA and BSE were analysed using a multivariable logistic regression for Fiji and Kashmir separately. RESULTS: Data were collected from 399 and 1982 women in Kashmir and Fiji, respectively. Of 1968 women in Fiji 57% were deemed to have an acceptable BCA compared to only 7.3% of 395 women in Kashmir. Having some education was associated with having BCA with an odds ratio of 4.7 (1.7-13) in Fiji and 10 (1.7-59) in Kashmir. Of 1976 women in Fiji 40% had tertiary education while 40% of 392 women in Kashmir had no education at all. The marital status was similar in both samples (n = 1973 and 395) with 68-69% being married and 21-26% being single. The lack of female doctors or nurses with whom to discuss issues, was perceived as a problem in both countries. CONCLUSIONS: The key finding is an association between having any level of education and BCA. This correlation was much stronger than for a family history of breast cancer and BCA. Hence, general education to illiterate women may reduce the proportion of women in low-income countries presenting with advanced-stage breast cancer.


Assuntos
Neoplasias da Mama/diagnóstico , Autoexame de Mama/psicologia , Autoexame de Mama/estatística & dados numéricos , Conhecimentos, Atitudes e Prática em Saúde , Adulto , Neoplasias da Mama/epidemiologia , Neoplasias da Mama/psicologia , Estudos Transversais , Escolaridade , Feminino , Fiji/epidemiologia , Humanos , Índia/epidemiologia , Estado Civil , Prognóstico , Estudos Prospectivos , Inquéritos e Questionários , Adulto Jovem
2.
Orbit ; 39(6): 426-432, 2020 Dec.
Artigo em Inglês | MEDLINE | ID: mdl-31856620

RESUMO

Conjunctival orbital cysts are rare; they are typically either conjunctival dermoid or conjunctival epithelial cysts - congenital or acquired (inclusion). We describe the case of a 15-month-old girl presenting with strabismus and proptosis who had a retrobulbar intraconal cystic lesion displacing the optic nerve, with an adjacent middle cranial fossa anomaly. Aspiration of the orbital cyst tested positive for asialotransferrin, raising the suspicion of a direct communication with cerebrospinal fluid (CSF). Subsequent fine cut CT scanning disproved any connection with the intracranial space, and the cyst was excised complete and intact. Histopathology showed a conjunctival epithelial cyst. To our knowledge, this is the first case report in the literature of an asialotransferrin positive pediatric orbital conjunctival epithelial cyst. It is of clinical relevance as it explores the possibility of either a false positive asialotransferrin or potentially a prior developmental communication with the subarachnoid space. These two diagnostic possibilities are discussed.


Assuntos
Assialoglicoproteínas/metabolismo , Biomarcadores/metabolismo , Doenças da Túnica Conjuntiva/diagnóstico por imagem , Cisto Epidérmico/diagnóstico por imagem , Doenças Orbitárias/diagnóstico por imagem , Transferrina/análogos & derivados , Doenças da Túnica Conjuntiva/metabolismo , Doenças da Túnica Conjuntiva/patologia , Cisto Epidérmico/metabolismo , Cisto Epidérmico/patologia , Feminino , Humanos , Lactente , Imageamento por Ressonância Magnética , Doenças Orbitárias/metabolismo , Doenças Orbitárias/patologia , Tomografia Computadorizada por Raios X , Transferrina/metabolismo
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