RESUMO
The genus Acremonium (formerly known as Cephalosporium) is a large polyphyletic fungal genus that comprises approximately 150 phylogenetically distant species, commonly isolated from the environment. Clinical cases concern mostly superficial infections after traumatic inoculation, but there are reports of opportunistic invasive infections in immunocompromised patients. Acremonium kiliense has been described as a cause of mycetoma, keratitis, endophthalmitis, endocarditis, and continuous ambulatory peritoneal dialysis-associated peritonitis. We describe an unusual cluster of possible catheter-related bloodstream infections due to this pathogen in patients who underwent haematopoietic cell transplantation.
Assuntos
Acremonium/isolamento & purificação , Fungemia/microbiologia , Transplante de Células-Tronco Hematopoéticas , Micoses/sangue , Acremonium/efeitos dos fármacos , Acremonium/patogenicidade , Adulto , Antifúngicos/farmacologia , Farmacorresistência Fúngica Múltipla , Feminino , Fungemia/tratamento farmacológico , Doença de Hodgkin/patologia , Doença de Hodgkin/terapia , Humanos , Hospedeiro Imunocomprometido , Leucemia Mieloide/patologia , Leucemia Mieloide/terapia , Masculino , Testes de Sensibilidade Microbiana , Micoses/tratamento farmacológico , Micoses/microbiologia , Leucemia-Linfoma Linfoblástico de Células Precursoras/patologia , Leucemia-Linfoma Linfoblástico de Células Precursoras/terapia , Transplante Homólogo , Adulto JovemRESUMO
Candida hellenica var. hellenica (teleomorph Zygoascus meyerae) is a member of the genus Zygoascus that comprises species isolated from environmental sources such as damaged grapes. A case of a possible pneumonia due to this uncommon yeast in a pediatric oncology patient suffering from acute myeloid leukemia is described. To our knowledge, this is the first report concerning the isolation of the species from a pediatric patient and the second in humans.