1.
Cytogenet Cell Genet
; 56(1): 14-7, 1991.
Artigo
em Inglês
| MEDLINE
| ID: mdl-2004549
RESUMO
Whole-arm translocations in five leukemic patients were studied using nonisotopic in situ hybridization with alpha satellite DNA and simple satellite chromosome-specific DNA probes to detect the target sequences. The results show that this technique provides additional information on the involvement of these DNA sequences in whole-arm translocations.
Assuntos
DNA de Neoplasias/genética , Leucemia/genética , Translocação Genética , Adulto , Idoso , Centrômero , Criança , Sondas de DNA , DNA de Neoplasias/análise , DNA Satélite , Feminino , Humanos , Cariotipagem , Leucemia/sangue , Masculino , Pessoa de Meia-Idade , Hibridização de Ácido Nucleico
2.
Cancer Genet Cytogenet
; 45(1): 49-53, 1990 Mar.
Artigo
em Inglês
| MEDLINE
| ID: mdl-2302685
RESUMO
We have found one or more copies of i(12p) in an ovarian germ cell tumor, histologically a yolk sac tumor. This chromosome marker is characteristically associated with germ cell tumors in males. This report indicates that further investigation is necessary to establish the role of the i(12p) marker in the pathogenesis of germ cell tumors also in females.