RESUMO
Peripheral blood T-cell subpopulations were evaluated in 36 patients with clinically different types of warts, subdivided in 4 groups (common, genital, flat and plantar warts). A significant decrease was found in OKT3 and OKT4 subsets total count and in OKT4/OKT8 ratio in patients with common and genital warts as compared with controls. Only in common and genital warts did we also observe a significant decrease of percentage of OKT4 subset. No significant difference of considered parameters was observed in flat and plantar warts as compared to controls, apart from a significant increase in number of OKT8 subset in flat warts. We then discuss this different status of C.M.I. in patients with different clinical warts, stressing the importance of various types of HPV.
Assuntos
Linfócitos/classificação , Verrugas/sangue , Adolescente , Adulto , Idoso , Anticorpos Monoclonais , Feminino , Humanos , Masculino , Pessoa de Meia-Idade , Verrugas/classificaçãoRESUMO
One hundred and four patients with psoriasis, treated in regimen of Day Hospital, have been examined. The diagnosis was widespread plaque type psoriasis (67.3%), guttate psoriasis (18.3%) and nail psoriasis (1.0%). Furthermore psoriatic erythroderma has been observed in 2.9% and pustular psoriasis of Barber in 1.9%. 10% of the patients showed psoriatic arthritis. 71.2% of the patients have been successfully treated with UVB and PUVA irradiation therapy (respectively 86.6% and 70.0% of complete clearing or marked improvement). Etretinate and topical therapy were successful (respectively 67.0% and 70.0% of complete clearing or marked improvement). Day Hospital has proved to be the ideal regimen for the treatment and control of psoriatic patients.
Assuntos
Psoríase/terapia , Administração Tópica , Adolescente , Adulto , Idoso , Anti-Inflamatórios/administração & dosagem , Benzenossulfonatos , Criança , Pré-Escolar , Alcatrão/administração & dosagem , Hospital Dia , Etretinato/uso terapêutico , Feminino , Glucocorticoides , Humanos , Masculino , Pessoa de Meia-Idade , Pomadas , Terapia PUVA , Psoríase/tratamento farmacológico , Psoríase/radioterapia , Salicilatos/administração & dosagem , Terapia UltravioletaRESUMO
The hands of 40 patients with psoriasis were examined by conventional and direct magnification radiograms. In 5 cases the hands showed typical psoriatic arthropathy. In 5 other cases only small calcifications in the soft tissues at distal interphalangeal joints were visible: according to clinical and laboratory data, these lesions could be in connection with psoriatic arthritis.