RESUMO
AIM: To evaluate the possible relationship between high levels of CA-125 and long-term prognosis in chronic heart failure patients after they undergo a cardiac transplantation (CT). MATERIALS & METHODS: We retrospectively studied all patients who underwent a CT and had a previous determination of CA-125. Congestive patients and those whose survival was <1 year after CT were excluded. RESULTS: Of 55 patients, 23 had elevated CA-125 levels (>35 U/ml). After CT, survival was significantly inferior in this group (96.3 vs 81%, 84.9 vs 64%, 70.7 vs 32.9% at 2, 5 and 8 years, p = 0.014). CA-125 >35 U/ml was the only factor independently associated to long-term mortality (OR: 3.94; 95% CI: 1.2-12.82; p = 0.023). CONCLUSION: Noncongestive patients with high levels of CA-125 had inferior long-term survival after CT.
Assuntos
Antígeno Ca-125/sangue , Rejeição de Enxerto/diagnóstico , Insuficiência Cardíaca/terapia , Transplante de Coração , Adulto , Biomarcadores/sangue , Feminino , Seguimentos , Rejeição de Enxerto/mortalidade , Transplante de Coração/efeitos adversos , Humanos , Masculino , Pessoa de Meia-Idade , Razão de Chances , Prognóstico , Estudos Retrospectivos , Taxa de SobrevidaRESUMO
We report a case of giant blood cyst originating from the anterior mitral valve leaflet, which was discovered during a two-dimensional echocardiography examination performed for investigation of a systolic murmur in a 34-year-old healthy man. Three-dimensional microbubble-enhanced images showed a heart-shape appearance that may be pathognomonic for blood cyst of the mitral valve.