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1.
Sci Rep ; 13(1): 4547, 2023 03 20.
Artigo em Inglês | MEDLINE | ID: mdl-36941282

RESUMO

The COVID-19 pandemic and the political and health measures have profoundly affected the health of our populations. However, very few studies have been published assessing its impact using a prospective cohort. The aim of this study is to describe the impact on physical and mental health due to the COVID-19 pandemic in the general population in Spain, and according to COVID-19 clinical status, during the first year of the pandemic. A longitudinal cohort study with two online surveys were performed on a representative sample of the adult Spanish population before (N = 2005, October/November 2019) and during the pandemic (N = 1357, November/December 2020). We assessed disability using the World Health Organisation Disability Assessment Schedule (WHODAS), major depressive episode (MDE) and suicidal thoughts and behaviours (STB), using an adapted version of the Composite International Diagnostic Interview (CIDI 3.0); generalised anxiety disorder (GAD) using the GAD-7 scale; post-traumatic stress disorder (PTSD) symptoms using the PTSD checklist for DSM-5 (PCL-5). For physical health, there was a statistically significant loss of weight (mean/SD) (T0, 73.22/15.56 vs. T1, 71.21/11.94), less use of tobacco (T0, 11.4% vs. T1, 9.0%) and decreased disability (mean/SD) (T0, 21.52/9.22 vs. T1, 19.03/7.32). For mental health, there was a significant increase in MDE (T0, 6.5% vs. T1, 8.8%) and in the prevalence of GAD (T0, 13.7% vs. T1, 17.7%). The prevalence of STB (T0, 15.1% vs. T1, 7.1%) significantly decreased. Individuals who declared they had been diagnosed with COVID-19 (3.6%) showed a worsening in physical health and an increase in mental health problems and PTSD symptoms. Although suicide risk during the first year of the pandemic was significantly less, many suicide risk factors increased: such as the incidence and persistence of MDE and GAD, the presence of PTSD symptoms in those diagnosed with COVID-19, and a worsening in self-assessed health status. We expect an increase in STB in the population in the long-term. Future research should gather information about the long-term impact of the pandemic.


Assuntos
COVID-19 , Transtorno Depressivo Maior , Humanos , Adulto , Saúde Mental , Pandemias , Estudos Longitudinais , Transtorno Depressivo Maior/psicologia , Estudos Prospectivos , COVID-19/epidemiologia
2.
Expert Rev Respir Med ; 16(2): 247-252, 2022 02.
Artigo em Inglês | MEDLINE | ID: mdl-34651540

RESUMO

BACKGROUND: Biomarkers of tobacco consumption may play a role in the lung cancer risk assessment. However, the role of salivary biomarkers has not been well studied. The aim of this study is to assess the use of salivary biomarkers of tobacco consumption as lung cancer screening criterion. RESEARCH DESIGN AND METHODS: Data came from the Determinants of cotinine phase 3 project (Barcelona, 2013-2014). We compared the concentrations of TSNAs, including NNAL, NNN and NNK, and cotinine, in saliva samples of 142 daily smokers from the general population according to their risk of lung cancer. High risk of lung cancer was defined as per the inclusion criteria in the US National Lung Screening Trial (NLST) and in the Dutch-Belgian lung cancer screening trial (NELSON). RESULTS: Among daily smokers accomplishing the age criterion for lung cancer screening, salivary concentrations of cotinine, NNAL and NNK adjusted for sex were significantly higher (p-value < 0.05) in daily smokers at high risk of lung cancer compared to smokers not at high risk according to both NELSON and NLST criteria. CONCLUSIONS: Saliva concentrations of cotinine, NNAL and NNK may be used as additional criteria for lung cancer screening. Further research on this topic is guaranteed.


Assuntos
Neoplasias Pulmonares , Nitrosaminas , Biomarcadores , Detecção Precoce de Câncer , Humanos , Pulmão , Neoplasias Pulmonares/diagnóstico , Neoplasias Pulmonares/epidemiologia , Neoplasias Pulmonares/etiologia , Fumantes , Fumar/efeitos adversos , Fumar/epidemiologia , Uso de Tabaco
4.
J Public Health (Oxf) ; 42(1): 90-97, 2020 02 28.
Artigo em Inglês | MEDLINE | ID: mdl-30608591

RESUMO

OBJECTIVES: The aim of this study was to describe the smoking prevalence, the smoking pattern, and the risk of lung cancer among women who participated in a cancer screening (breast, cervical and colorectal) in Spain. METHODS: We used data from the Spanish National Health Survey of 2011-12, a cross-sectional study of the adult Spanish population from women in the age of participation in the population cancer screening. We used two definitions of the high risk of lung cancer according to the National Lung Screening Trial (NLST) criteria and the NELSON criteria. RESULTS: Participation in screening was 76.6% in breast cancer, 6.6% in colorectal cancer, and 70.3% in cervical cancer. The percentage of current smokers was 17.1 of women who participated breast cancer, 15.4 of women who participated colorectal cancer, and 26.1 of women who participated cervical cancer. According to NLST criteria, the percentage of current smokers women who had a high risk of lung cancer was 23.1 for breast cancer, 23.5 for colorectal cancer and 4.5 for cervical cancer. These figures were higher with the NELSON criteria. CONCLUSION: At least 250 000 women in Spain have a high risk of lung cancer and are participating in a cancer screening programme. These programmes might be an opportunity for implementing specific interventions aiming to reduce this risk.


Assuntos
Detecção Precoce de Câncer , Neoplasias Pulmonares , Adulto , Estudos Transversais , Feminino , Humanos , Neoplasias Pulmonares/diagnóstico , Neoplasias Pulmonares/epidemiologia , Neoplasias Pulmonares/etiologia , Programas de Rastreamento , Fumar , Espanha/epidemiologia
5.
Arch Bronconeumol (Engl Ed) ; 56(5): 277-281, 2020 May.
Artigo em Inglês, Espanhol | MEDLINE | ID: mdl-31629546

RESUMO

INTRODUCTION: Lung cancer mortality is increasing in women. In Spain, estimates suggest that lung cancer mortality may soon surpass breast cancer mortality, the main cause of cancer mortality among women. The aim of this study was to estimate the proportion of women at high risk of developing lung cancer in a group of participants in a population-based breast cancer screening program. METHODS: Cross-sectional study in a sample of women who participated in a population-based breast cancer screening program in 2016 in Hospitalet de Llobregat (n=1,601). High risk of lung cancer was defined according to the criteria of the National Lung Screening Trial (NLST) and the Dutch-Belgian randomized lung cancer screening trial (NELSON). RESULTS: Around 20% of smokers according to NLST criteria and 40% of smokers according to NELSON criteria, and around 20% of former smokers according to both criteria, are at high risk of developing lung cancer. A positive and statistically significant trend is observed between the proportion of women at high risk and nicotine dependence measured with the brief Fagerström test. CONCLUSIONS: A high proportion of participants in this breast cancer screening program have a high risk of developing lung cancer and would be eligible to participate in a lung cancer screening program. Population-based breast cancer screening programs may be useful to implement lung cancer primary prevention activities.


Assuntos
Neoplasias da Mama , Neoplasias Pulmonares , Bélgica , Neoplasias da Mama/diagnóstico , Estudos Transversais , Detecção Precoce de Câncer , Feminino , Humanos , Neoplasias Pulmonares/diagnóstico , Fumar/efeitos adversos , Espanha
6.
Environ Res ; 179(Pt A): 108594, 2019 12.
Artigo em Inglês | MEDLINE | ID: mdl-31541906

RESUMO

INTRODUCTION: Lung cancer accounts for nearly 2 million deaths per year worldwide, the majority of cases due to smoking as the main risk factor associated. The aim of this study was to assess the relation between the level of implementation of tobacco control policies and the population at high risk of lung cancer in the European Union (EU). METHODS: The Special Eurobarometer 458 "Attitudes of Europeans towards tobacco and electronic cigarettes", conducted in 2017, and the Tobacco Control Scale (TCS) 2010, 2013, and 2016 were the sources of our data. High risk of lung cancer was defined by the inclusion criteria in the National Lung Screening Trial (NLST) and the Dutch-Belgian Lung Cancer Screening Trial (NELSON), the largest lung cancer screening trials carried out in the US and the EU. We calculated Spearman's rank correlation coefficients (rsp) and fitted multilevel generalized linear mixed models using the quasi-Poisson family to assess the correlation at the national level and analyze the association at the individual level, respectively, between the scores in the TCS (higher scores means better implementation of tobacco control policies) and the proportion of individuals at high risk of lung cancer in member states of the EU. RESULTS: The scores in the TCS 2010 were statistically negatively correlated with the current proportion of ever and former smokers at high risk according to NELSON criteria (-0.41; 95%CI -0.68, -0.04 and -0.49; 95%CI -0.73, -0.13, respectively). We observed statistically significant inverse associations between the scores in the TCS 2010 for the highest quartiles and the proportion of individuals at high risk of lung cancer according to both criteria. Non-statistically significant negative correlations and inverse associations were observed with other TCS. CONCLUSION: There is a lag between the implementation of tobacco control policies and the reduction of the rates of high risk of lung cancer. Member states should reinforce comprehensive tobacco control policies to reduce the population at high risk of lung cancer in the EU.


Assuntos
Neoplasias Pulmonares/epidemiologia , Nicotiana , Fumar/epidemiologia , Detecção Precoce de Câncer , Sistemas Eletrônicos de Liberação de Nicotina , União Europeia , Política de Saúde , Humanos , Fumar/legislação & jurisprudência
7.
Rev Esp Salud Publica ; 932019 Jul 24.
Artigo em Espanhol | MEDLINE | ID: mdl-31337747

RESUMO

OBJECTIVE: To know the support of tobacco regulation is a very important issue to advance in the tobacco control policies and reduce the passive exposure to tobacco. The aim of this study was to describe the attitudes towards forbidding smoking in private vehicles and public outdoor spaces. METHODS: This is a cross-sectional study of a representative sample (n=736) of the adult population (24+ years old) from Barcelona, Spain in 2013-2014. We calculated the percentages of individuals who had a favourable attitude towards smoking regulation in private vehicles and public outdoor spaces, their adjusted Odds ratios (aOR) and their 95% confidence intervals (95%CI) according to sex, age, educational level and smoking status through logistic regression. We used weighted data for all analyses in order to keep the representativeness of the population of Barcelona in 2013-2014. RESULTS: 61.7% of participants supported forbidding smoking in private vehicles and 89.5% supported forbidding it only in the presence of minors. The support to smoking regulation in public outdoor spaces varied from 42.5% to 84.7% in different settings. Smokers showed a less favourable attitude towards an extension of the smoking regulation to other settings: outdoor areas of university centres, outdoor areas of shopping centres and beaches and outdoor pools. CONCLUSIONS: A wide support exists to extend the smoking regulation to private vehicles, especially in the presence of children, and public outdoor spaces. This wide support could favour the extension of smoking regulation to these places to improve the population's health and to contribute to denormalise tobacco use among the population.


OBJETIVO: Conocer el apoyo a la regulación del consumo de tabaco es una pieza clave para avanzar en las políticas de control del tabaquismo y reducir la exposición pasiva al tabaco. El objetivo de este trabajo fue describir las actitudes hacia la prohibición de fumar en los vehículos privados y espacios públicos al aire libre. METODOS: studio transversal de una muestra representativa (n=736) de la población adulta (mayor de 24 años) de la ciudad de Barcelona, España, realizado en 2013-2014. Se calcularon el porcentaje de individuos que tenían una actitud favorable a la regulación del consumo de tabaco en el interior de vehículos privados y espacios públicos al aire libre, las Odds Ratio ajustadas (ORa) y sus intervalos de confianza al 95% (IC95%) según sexo, edad, nivel de estudios y estatus de consumo de tabaco mediante un modelo de regresión logística. Se utilizaron pesos de probabilidad inversa para mantener la representatividad de la población de Barcelona en 2013-2014. RESULTADOS: El 61,7% de los participantes estuvo a favor de la prohibición de fumar dentro de los vehículos privados y el 89,5% de prohibirlo sólo en presencia de menores. El apoyo a la regulación del consumo de tabaco en espacios exteriores varió entre 42,5% hasta 84,7% dependiendo del ambiente. Los fumadores mostraron una actitud menos favorable a la ampliación de la regulación a otros espacios: zonas exteriores de los centros universitarios, zonas exteriores de los centros comerciales y playas y piscinas descubiertas. CONCLUSIONES: Existe un amplio apoyo a la extensión de la regulación del consumo del tabaco en el interior de vehículos privados, especialmente en presencia de menores, y espacios públicos al aire libre. Este amplio apoyo podría favorecer la ampliación de la regulación del consumo de tabaco a estos espacios a fin de mejorar la salud de la población y al mismo tiempo contribuir a la desnormalización del consumo de tabaco entre la población.


Assuntos
Atitude Frente a Saúde , Veículos Automotores/legislação & jurisprudência , Prevenção do Hábito de Fumar/legislação & jurisprudência , Fumar/legislação & jurisprudência , Poluição por Fumaça de Tabaco/legislação & jurisprudência , Poluição por Fumaça de Tabaco/prevenção & controle , Adulto , Idoso , Idoso de 80 Anos ou mais , Estudos Transversais , Feminino , Humanos , Masculino , Pessoa de Meia-Idade , Espanha
8.
Rev Esp Salud Publica ; 932019 Jul 16.
Artigo em Espanhol | MEDLINE | ID: mdl-31303641

RESUMO

OBJECTIVE: Pediatric population is the most vulnerable to secondhand smoke (SHS), exposure being households the main source of exposure in children. The objective of this study is to describe smoke-free households and the prevalence of SHS in the pediatric population (from 3 to 36 months) in Spain. METHODS: Cross-sectional study with 1,368 parents, mothers or guardians with children from 3 to 36 months carried out in Spain from March to November of 2017 through an online questionnaire as part of the EPISON study. Information was collected on the voluntary adoption of tobacco use regulations at home and SHS exposure at home and other environments. We calculated prevalences and Odds Ratio adjusted (ORa) for sex, age, level of education, and smoking status. RESULTS: 87.6% of respondents claimed to have a smoke-free home. 12.4% of respondents had partial regulation or did not have regulation at home, increasing up to 26.0% when the parent was a smoker or to 21.8% when the parent had primary or lower education. 5.4% of parents reported SHS exposure in their children at their homes, rising to 14.5% when it occurs in other environments, increasing with statistically significant differences between smoking parents and parents with lower educational level. CONCLUSIONS: The smoke-free homes are the majority; but SHS exposure to tobacco at home persists in children under 3 years of age, especially in families with a lower educational level. Therefore, awareness-raising campaigns on the effects of passive exposure on minors among families with.


OBJETIVO: La población pediátrica es la más vulnerable a la exposición pasiva al humo ambiental del tabaco (HAT), siendo los hogares la fuente principal de exposición en niños. El objetivo de este estudio fue describir los hogares libres de humo y la prevalencia de exposición pasiva al HAT en la población pediátrica (de 3 a 36 meses) en España. METODOS: Estudio transversal con 1.368 padres, madres o tutores con hijos de 3 a 36 meses realizado en España de marzo a noviembre de 2017 mediante cuestionario online como parte del estudio EPISON. Se recogió información sobre la adopción voluntaria de normas de consumo de tabaco en el hogar y exposición al HAT en casa y otros ambientes. Se calcularon las prevalencias y las Odds Ratio ajustadas (ORa) por sexo, edad, nivel educativo y consumo de tabaco. RESULTADOS: El 87,6% de los encuestados afirmó tener un hogar libre de humo. El 12,4% de los encuestados tenían regulación parcial o no tenían ninguna regulación en el hogar, incrementándose hasta el 26% cuando el progenitor era fumador o al 21,8% cuando tenía estudios primarios o inferiores. El 5,4% de los padres refirió exposición pasiva al tabaco en niños en sus hogares, elevándose hasta el 14,5% cuando la exposición se produjo en otros ambientes, incrementándose de forma estadísticamente significativa la diferencia entre los padres fumadores y con menor nivel educativo. CONCLUSIONES: Los hogares libres de humo son mayoritarios, pero persiste la exposición pasiva al tabaco en el hogar con niños menores de 3 años, especialmente en familias con menor nivel educativo. Por ello, se deberían incentivar campañas de sensibilización sobre los efectos de la exposición pasiva en menores, especialmente en familias con menos recursos.


Assuntos
Nicotiana/efeitos adversos , Poluição por Fumaça de Tabaco/prevenção & controle , Poluição por Fumaça de Tabaco/estatística & dados numéricos , Adulto , Pré-Escolar , Estudos Transversais , Escolaridade , Família , Características da Família , Feminino , Humanos , Masculino , Razão de Chances , Pais , Prevalência , Fumar , Espanha/epidemiologia , Inquéritos e Questionários , Uso de Tabaco , Adulto Jovem
9.
Environ Res ; 172: 73-80, 2019 05.
Artigo em Inglês | MEDLINE | ID: mdl-30771628

RESUMO

OBJECTIVE: To compare tobacco-specific nitrosamines (TSNAs) measured in saliva according to different types of tobacco smoked in a sample of smokers of the city of Barcelona (Spain). METHODS: We used data from a cross-sectional study of a sample of the adult smoking population of Barcelona, Spain in 2013-2014 (n = 165). We classified smokers in five groups according to the type of tobacco smoked: a) manufactured cigarettes only, b) roll-your-own (RYO) cigarettes only, c) dual smokers (both manufactured and RYO cigarettes), d) manufactured plus other types of tobacco products different from RYO and e) other types of tobacco products different from manufactured and RYO cigarettes. We calculated the geometric mean (GM) and geometric standard deviation (GSD) of TSNAs concentration in saliva (pg/mL), including N'-nitroaonornicotine (NNN), 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK) and 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanol (NNAL) according to the five tobacco groups. We also described all TSNAs concentration in each tobacco group stratified by the number of cigarettes smoked per day. RESULTS: Smokers from the RYO cigarette group had higher TSNAs concentration than smokers from the manufactured cigarette group: 13 pg/mL vs 4.9 pg/mL of NNN, 1.9 pg/mL vs 1.7 pg/mL in NNK and 1.1 pg/mL vs 0.9 pg/mL of NNAL. There were significant differences in NNN concentrations between smokers of RYO vs manufactured cigarettes. The higher the number of cigarettes smoked, the higher the TSNAs concentrations. After adjusted by number of cigarettes smoked, there were not statistically significant differences in TSNAs between RYO and manufactured cigarettes. CONCLUSIONS: Our data shows that RYO cigarette is at least as hazardous as manufactured cigarettes. Regulating RYO tobacco prices could be an effective strategy to control tobacco use.


Assuntos
Nicotiana , Nitrosaminas , Saliva , Fumantes , Produtos do Tabaco , Adulto , Estudos Transversais , Humanos , Nitrosaminas/análise , Saliva/química , Fumantes/estatística & dados numéricos , Espanha , Nicotiana/química , Nicotiana/classificação
10.
Cancer Epidemiol ; 57: 140-147, 2018 12.
Artigo em Inglês | MEDLINE | ID: mdl-30497060

RESUMO

Background Lung cancer mortality accounts for over 266,000 deaths in the European Union (EU) every year, most of them attributed to smoking. The aim of this study was to estimate the prevalence of the adult population at high risk of developing lung cancer in the EU in 2014. Methods This is a cross-sectional study. We used data from the Special Eurobarometer 429 (n = 27,801). The fieldwork was conducted between November-December 2014. High risk of lung cancer was defined using the criteria of the National Lung Screening Trial (NLST) and the Dutch-Belgian Lung Cancer Screening Trial (NELSON). Results One out of ten smokers (11.6% of men and 9.6% of women) according to NLST criteria and one out of four smokers (24.6% of men and 22.4% of women) according to NELSON criteria are currently at high risk of lung cancer in the EU. According to both criteria, the prevalence of former smokers at high risk of lung cancer is under 10%. Conclusion Around 17 million citizens in the EU according to NLST criteria and 34 million according to NELSON criteria (around 4% and 8% of the adult population, respectively) are at high risk of developing lung cancer. Since the implementation of lung cancer screening programs still remains controversial, primary prevention activities should be encouraged.


Assuntos
Neoplasias Pulmonares/epidemiologia , Adulto , Idoso , Estudos Transversais , União Europeia , Feminino , Humanos , Neoplasias Pulmonares/etiologia , Masculino , Pessoa de Meia-Idade , Prevalência , Fumar Tabaco/efeitos adversos
11.
Pediatr Res ; 84(5): 645-649, 2018 11.
Artigo em Inglês | MEDLINE | ID: mdl-30194415

RESUMO

INTRODUCTION: The knowledge and beliefs about what is thirdhand smoke (THS) are limited. Our objective is to characterize the knowledge and beliefs about THS in parents of children under 3 years old in Spain. METHODS: A cross-sectional study (n = 1406 parents) was conducted online in 2017. We collected information about the knowledge of THS given later, written information with the definition of THS, and asking about beliefs of the effects of THS on children's health. RESULTS: A total of 27% of the respondents had heard about THS. We only found significant differences among smoking status, being the smokers who declare higher knowledge about THS. A total of 86% of the respondents believed that THS is harmful to their children with statistically significant differences according to educational level, higher among parents with a university degree (ORa = 2.6), and according to the previous knowledge on THS (ORa = 2.1). CONCLUSIONS: This is the first study in Europe to describe the knowledge and belief of THS. Around 3 out of 10 parents have heard about THS and more than 8 out of 10 parents believed that THS is harmful to their children. Currently, they were not aware of THS but after providing brief information about it, most of them agreed that THS exposure is harmful to their children.


Assuntos
Conhecimentos, Atitudes e Prática em Saúde , Pais/psicologia , Poluição por Fumaça de Tabaco , Adulto , Pré-Escolar , Estudos Transversais , Feminino , Humanos , Lactente , Masculino , Espanha
12.
Cancer Res ; 78(15): 4436-4442, 2018 08 01.
Artigo em Inglês | MEDLINE | ID: mdl-30068667

RESUMO

Among women, lung cancer mortality rates have surpassed those for breast cancer in several countries. This reflects the breast cancer mortality declines due to access to screening and effective treatment alongside the entrance of certain countries in stages of the tobacco epidemic in which smoking becomes more prevalent in women. In this study, we project lung and breast cancer mortality until 2030 in 52 countries. Cancer mortality data were obtained from the WHO Mortality Database. Age-standardized mortality rates (ASMR), per 100,000, were calculated (direct method) for 2008 to 2014 and projected for the years 2015, 2020, 2025, and 2030 using a Bayesian log-linear Poisson model. In 52 countries studied around the world, between 2015 and 2030, the median ASMR are projected to increase for lung cancer, from 11.2 to 16.0, whereas declines are expected for breast cancer, from 16.1 to 14.7. In the same period, the ASMR will decrease in 36 countries for breast cancer and in 15 countries for lung cancer. In half of the countries analyzed, and in nearly three quarters of those classified as high-income countries, the ASMR for lung cancer has already surpassed or will surpass the breast cancer ASMR before 2030. The mortality for lung and breast cancer is higher in high-income countries than in middle-income countries; lung cancer mortality is lower in the latter because the tobacco epidemic is not yet widespread. Due to these observed characteristics of lung cancer, primary prevention should still be a key factor to decrease lung cancer mortality.Significance: The mortality for lung and breast cancer is projected to be higher in high-income countries than in middle-income countries, where lung cancer mortality is expected to surpass breast cancer mortality before 2030. Cancer Res; 78(15); 4436-42. ©2018 AACR.


Assuntos
Neoplasias da Mama/mortalidade , Neoplasias Pulmonares/mortalidade , Adolescente , Adulto , Idoso , Idoso de 80 Anos ou mais , Teorema de Bayes , Mama/patologia , Neoplasias da Mama/patologia , Criança , Pré-Escolar , Feminino , Humanos , Lactente , Recém-Nascido , Neoplasias Pulmonares/patologia , Pessoa de Meia-Idade , Fumar/efeitos adversos , Nicotiana/efeitos adversos , Adulto Jovem
13.
Environ Res ; 167: 341-371, 2018 11.
Artigo em Inglês | MEDLINE | ID: mdl-30096604

RESUMO

OBJECTIVE: The objective of this study is to perform a comprehensive review of the literature about thirdhand smoke (THS). METHODS: Systematic review of all aspects of THS. Standard methodological procedures were used to search the following databases through April 2018: MEDLINE, Cumulative Index to Nursing and Allied Health Literature (CINAHL), Cochrane Central Register of Controlled Trials (CENTRAL), and Web of Science (WOS) in Indo-European languages. To identify published grey literature, the first 200 hits from Google Scholar™ were evaluated. Clinical trial databases, conference proceedings, and reference lists from the identified articles were also searched. Two unblinded review authors independently assessed trials for inclusion in the review. These same reviewers also extracted study data in accordance with PRISMA guidelines. The study protocol was registered with PROSPERO (CRD42018083619). RESULTS: Sixty-eight articles were included in this systematic review. Of these, 28 analyzed the concentration of nicotine as a component of THS (the most commonly-used method to measure THS in those studies was chromatography, followed by the mass spectrometry), 21 evaluated the exposure and impact of THS on health (11 studies analyzed the effect of THS in cells [human and animal], 4 in animals, 1 in adults, and 5 in children), 16 investigated the beliefs, behaviours, and policies related to THS, and 3 evaluated other aspects such as THS in e-cigarettes or hookahs. In these 68 studies, THS was determined by measuring the following components: nicotine (30 studies), nitrosamines (17 studies) and cotinine (15 studies). The findings from most of these studies suggest a potential health impact of THS exposure (i.e.: cytotoxicity, metabolic alterations in metabolism, in glycemia; or cell structure; alterations in liver, lung, skin and behaviour in mice), and low awareness about the risks of THS among the general population. CONCLUSIONS: Numerous specific biomarkers of THS were evaluated, with the most common being nicotine, nitrosamines, and cotinine. The most common method of preparing THS dust samples were cotton wipes, while chromatography, used alone or coupled with mass spectrometry, was the most common analytical technique. We have tried to establish common bases after reviewing all the current literature of the THS although, there is great heterogeneity between the studies and we have not always succeeded. The studies in this review demonstrate the harmful effects of THS on health in cells, in animal models, and in people including children. However, in people, the long-term effects remain unknown and more research is needed. These studies show that knowledge about THS and its potential harmful effects are poorly understood among the general population. For this reason, THS should receive greater emphasis in education and awareness policies.


Assuntos
Sistemas Eletrônicos de Liberação de Nicotina , Exposição Ambiental/efeitos adversos , Poluição por Fumaça de Tabaco/efeitos adversos , Animais , Cotinina , Humanos , Camundongos , Nicotina , Nitrosaminas , Fumaça , Nicotiana
14.
Addict Behav ; 87: 101-108, 2018 12.
Artigo em Inglês | MEDLINE | ID: mdl-29975878

RESUMO

BACKGROUND: The aim of this study is to assess the impact of the Spanish tobacco control legislation on smoking behavior and salivary cotinine concentration among smokers. METHODS: We used data from a longitudinal study, before (2004-2005) and after (2013-2014) the implementation of the two national smoking bans (in 2006 and 2011), in a representative sample of adults (≥16 years old) from Barcelona (Spain). We only analyzed a subsample of continuing smokers (n = 116). We conducted a survey on smoking behavior and obtained saliva sample for cotinine analyses. For this report, we analyzed a subsample of continuing smokers (n = 116). We calculated geometric means (GM). RESULTS: Among continuing smokers, salivary cotinine concentration significantly increased by 28.7% (GM from 91.7 ng/ml to 117.3 ng/ml, p = 0.015) after the implementation of the two Spanish smoke-free bans. Nonetheless, no pattern of change was observed in the self-reported number of cigarettes smoked daily. CONCLUSIONS: Our study shows a significant increase in the salivary cotinine concentration among adult continuing smokers after both Spanish legislations. This increase could be due to differences in smoking topography (increase in the depth of inhalation when smoking) along with changes in the type of tobacco smoked (increase in smoking roll-your-own cigarettes or mixed use of roll-your-own and manufactured cigarettes). Our results suggest the need to extend tobacco control policies, focusing on the reduction of use of any type of tobacco product and implementing better treatment to help smokers stop smoking.


Assuntos
Fumar Cigarros/legislação & jurisprudência , Política Antifumo/legislação & jurisprudência , Abandono do Hábito de Fumar , Produtos do Tabaco/estatística & dados numéricos , Adolescente , Adulto , Idoso , Fumar Cigarros/metabolismo , Fumar Cigarros/terapia , Cotinina/análise , Feminino , Humanos , Estudos Longitudinais , Masculino , Pessoa de Meia-Idade , Saliva/química , Fumantes , Espanha , Adulto Jovem
15.
Prev Med ; 111: 67-72, 2018 06.
Artigo em Inglês | MEDLINE | ID: mdl-29476766

RESUMO

The objective of this work is to describe the acceptability of some tobacco products regulations and to explore their relation with tobacco control legislation levels in Europe. We used data on tobacco control activities in Europe in 2007, 2010 and 2013 measured by the Tobacco Control Scale (TCS) and data regarding attitudes about tobacco control regulations (i.e. adding picture health warnings on all packages of tobacco products or increasing taxes on tobacco products) from the Special Eurobarometer of 2009, 2012 and 2014 (n = 80,831). We calculated the prevalence ratio of favorable attitudes towards tobacco products restrictions in the reference year 2009 vs. the most current year (i.e. 2009 vs 2014), and the effect of previous TCS scores on the attitudes towards tobacco products regulations adjusted for sociodemographic variables. Strong support for the studied tobacco products regulations, which modestly increased over time, was observed. A positive relation was generally observed between TCS scores and support for the studied tobacco products regulations at both the ecological and individual level. A positive correlation was found between TCS scores and support for increasing taxes on tobacco products (rsp:0.29; 95%CI: 0.10, 0.48) at the ecological level, while at the individual level, the positive association was more remarkable in the case of support for adding large health warning labels to packaging. In conclusion, support for the studied tobacco products regulations were positively related with European tobacco control levels of implementation both at the ecological and individual level.


Assuntos
Atitude , Regulamentação Governamental , Rotulagem de Produtos/legislação & jurisprudência , Política Pública/tendências , Produtos do Tabaco , Estudos Transversais , Europa (Continente)/epidemiologia , Humanos , Prevalência , Política Antifumo/legislação & jurisprudência , Fumar/epidemiologia , Impostos/economia
16.
Environ Res ; 158: 685-690, 2017 10.
Artigo em Inglês | MEDLINE | ID: mdl-28734255

RESUMO

OBJECTIVES: To describe the prevalence of e-cigarette users who use them in selected indoor public and workplaces, and private venues in Barcelona (Spain) in 2015. METHODS: This is a cross-sectional study of a sample of e-cigarette users (≥ 18 years) from Barcelona (n = 600). We calculated the proportion of e-cigarette users who used the device in public and private settings (in the last 30 days). We fit multivariate logistic regression models adjusted for sex and age to calculate the odds ratios (OR) with their 95% confidence intervals (CI) of e-cigarette use by socio-demographic factors, dual use and nicotine-containing e-cigarettes. RESULTS: The highest proportion of e-cigarette users who used them in public places was found at restaurants or bars (69.4%) and nightclubs or pubs (55.4%). Also being current conventional tobacco smokers (dual users) was significantly associated with lower use of e-cigarettes in workplaces (OR = 0.61, 95%CI:0.41-0.91), restaurants (OR = 0.66, 95%CI:0.45-0.97) and nightclubs (OR = 0.56, 95%CI:0.37-0.86). Moreover, being a nicotine-containing e-cigarette user was associated with higher odds of using the device in workplaces (OR = 2.01, 95%CI:1.34-3.01), and lower odds of using it in nightclubs (OR = 0.56, 95%CI:0.39-0.82). 96.8% of the included e-cigarette users declared to use the device at home. Being a current tobacco smoker was associated with increased odds of using e-cigarettes at home (OR = 3.17, 95%CI:1.22-8.22). CONCLUSIONS: E-cigarette use in private settings and in public settings where their use is not regulated by law is high. Therefore, the public health administration in Spain should consider expanding the prohibition of e-cigarette use to indoor public places and should take into account the possibility of exposure to aerosol from e-cigarettes.


Assuntos
Sistemas Eletrônicos de Liberação de Nicotina/estatística & dados numéricos , Adolescente , Adulto , Estudos Transversais , Feminino , Humanos , Masculino , Pessoa de Meia-Idade , Saúde Pública , Restaurantes , Espanha , Adulto Jovem
17.
Environ Res ; 158: 590-597, 2017 10.
Artigo em Inglês | MEDLINE | ID: mdl-28715788

RESUMO

OBJECTIVE: To describe the voluntary adoption of smoke-free homes and social attitudes in Spain towards banning smoking in vehicles in which children are present. METHODS: Cross-sectional study of a representative sample of the adult Spanish population age range, 18-75 years (n=1036). The field work was conducted via a computer-assisted telephone survey in March and April 2016. Survey respondents answered questions about smoking rules at home and attitudes towards a smoking ban in cars with or without children. Home smoking rules were defined as complete (smoking not allowed anywhere in the house), partial (smoking allowed in some areas inside the house) or absent (smoking allowed everywhere). RESULTS: Most (83.0%) of the surveyed population had some type of smoking restriction in place at home (45.6% complete and 37.5% partial). There were significant differences between groups according to age group (the highest prevalence was 86.1% from 66 to 75 years and the lowest prevalence was 77.8% from 46 to 65 years) and smoking status (the highest prevalence was 89.4% in people who had never been smokers and the lowest prevalence was 75.0% in current smokers) with regards to the prevalence of smoke-free homes (p<0.05), with partial bans more prevalent in smoking households (49.0%). Most (61.6%) of the population favored banning smoking in cars, and 90.1% supported a ban in cars carrying minors. Attitudes towards smoking regulation in cars (with or without children) varied significantly by age group (the highest prevalence was 81.9% from 66 to 75 years and the lowest prevalence was 54.5% from 18 to 45 years) and smoking status (the highest prevalence was 71.4% in people who had never been smokers and the lowest prevalence was 46.0% in current smokers). However, no significant differences were found with regard to attitudes towards smoking regulation in cars carrying children, regardless of sex, age, social class, or smoking status. CONCLUSION: Approximately half of the adult population in Spain have implemented a complete smoke-free rule at home. More than 9 out of 10 adults favor regulating smoking in cars in the presence of minors. These findings support the expansion of smoke-free regulations to include private vehicles, particularly when minors are in the car.


Assuntos
Atitude , Automóveis , Habitação , Política Antifumo , Prevenção do Hábito de Fumar , Poluição por Fumaça de Tabaco/prevenção & controle , Adulto , Idoso , Estudos Transversais , Feminino , Humanos , Masculino , Pessoa de Meia-Idade , Espanha , Poluição por Fumaça de Tabaco/análise , Adulto Jovem
18.
Addict Behav ; 75: 30-35, 2017 12.
Artigo em Inglês | MEDLINE | ID: mdl-28683343

RESUMO

BACKGROUND: In Spain, two smoke-free laws have been passed after the approval of the WHO-FCTC. This study assesses the impact of these Spanish smoking legislations on the active and passive smoking through a population cohort in Barcelona (Spain). METHODS: This is a longitudinal study before and after the implementation of two national smoking bans in Spain in a representative sample (n=1245) of adults (≥16years old) from Barcelona (Spain) surveyed in 2004-2005 and followed-up in 2013-2014. The final sample analyzed was 736 individuals. Both questionnaires (before and after the two laws) included the same variables about active and passive smoking. We calculated the prevalence and the prevalence ratio (PR, with their 95% confidence intervals, 95% CI) of smoking cigarettes and hand-rolled tobacco and also the prevalence of exposure to secondhand smoke (SHS) at home, work, public transport, leisure time and at any setting after vs. before Spanish legislations. RESULTS: After the implementation of the two Spanish smoke-free bans, a significant decrease was observed in the smoking prevalence (from 34.5% to 26.1%, PR=0.76, p<0.001), in the average cigarettes per day (median from 15.2 to 10.0, p<0.001), and in the percentage of conventional tobacco consumption (from 92.6% to 74.4%, PR=0.80, p<0.001). Furthermore, a significant increase in the use of hand-rolled tobacco (from 6.1% to 30.9%, PR=5.07, p<0.001) and other tobacco products (from 17.1% to 32.8%, PR=1.92, p<0.001) was observed. In addition, a significant decrease in the self-reported SHS exposure was observed in all the assessed settings (home, work, transport, and leisure time). CONCLUSIONS: The implementation of the two smoke-free legislations in Spain is related to a reduction in smoking prevalence and SHS exposure. However, the smoking of other tobacco products, particularly hand-rolled tobacco, has increased among young population.


Assuntos
Política Antifumo/legislação & jurisprudência , Fumar/epidemiologia , Poluição por Fumaça de Tabaco/estatística & dados numéricos , Fumar Tabaco , Adolescente , Adulto , Idoso , Feminino , Humanos , Estudos Longitudinais , Masculino , Pessoa de Meia-Idade , Prevalência , Espanha/epidemiologia , Adulto Jovem
19.
Gac Sanit ; 31(5): 436-438, 2017.
Artigo em Espanhol | MEDLINE | ID: mdl-28595990

RESUMO

Consumer panels are a market research method useful for gathering information about low-frequency or difficult-access customers. The objective of this field-note is to explain our experience using this method in a cross-sectional public health study on the use of electronic cigarettes. After taking into account other non-probabilistic sampling techniques to obtain a huge sample of electronic-cigarette users (n=600), in the end we decided to use consumer panels (recruiters) because of the relative short duration of the field work and the high representativeness of the sample.


Assuntos
Sistemas Eletrônicos de Liberação de Nicotina , Estudos Observacionais como Assunto , Saúde Pública , Adulto , Estudos Transversais , Feminino , Humanos , Masculino , Marketing , Pessoa de Meia-Idade
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