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1.
BMJ Case Rep ; 15(7)2022 Jul 22.
Artigo em Inglês | MEDLINE | ID: mdl-35868805

RESUMO

A man in his 70s with a history of multiple myeloma presented with a 4-day history of right ptosis and a rapidly enlarging upper eyelid mass. On examination, a large, firm, smooth, pink lesion was found to descend from the conjunctiva of the superior fornix. The patient underwent excision biopsy. Histopathological analysis demonstrated monoclonal plasma cells expressing light-chain kappa, consistent with extramedullary plasmacytoma. Clinical ophthalmic manifestations of multiple myeloma are rare but also diverse. Ocular surface manifestations of multiple myeloma are extremely uncommon. Variable examination findings mean those involving the conjunctiva and may be particularly challenging to diagnose. Secondary ocular extramedullary plasmacytoma, despite its rarity, should be considered in patients with multiple myeloma.


Assuntos
Blefaroptose , Mieloma Múltiplo , Plasmocitoma , Biópsia , Blefaroptose/etiologia , Túnica Conjuntiva/patologia , Humanos , Masculino , Mieloma Múltiplo/complicações , Mieloma Múltiplo/diagnóstico , Mieloma Múltiplo/patologia , Plasmocitoma/complicações , Plasmocitoma/diagnóstico , Plasmocitoma/patologia
2.
BMJ Case Rep ; 15(4)2022 Apr 22.
Artigo em Inglês | MEDLINE | ID: mdl-35459648

RESUMO

We report the use of Descemet stripping automated endothelial keratoplasty (DSAEK) for the treatment of sterile corneal perforation after trauma. In an eye with corneal perforation and cataract due to trauma, cataract surgery and DSAEK were performed. Corneal integrity was promptly restored and the patient avoided tectonic anterior lamellar and penetrating keratoplasty. DSAEK may be performed for the management of corneal perforation.


Assuntos
Catarata , Doenças da Córnea , Perfuração da Córnea , Ceratoplastia Endotelial com Remoção da Lâmina Limitante Posterior , Córnea/cirurgia , Doenças da Córnea/cirurgia , Perfuração da Córnea/etiologia , Perfuração da Córnea/cirurgia , Endotélio Corneano/cirurgia , Humanos , Ceratoplastia Penetrante
3.
BMJ Case Rep ; 20142014 Oct 27.
Artigo em Inglês | MEDLINE | ID: mdl-25349186

RESUMO

Two siblings, an 11-year-old boy and a 7-year-old girl presented with bilateral symmetrical ptosis and limited eye movements. Having already been reviewed on a number of occasions by a variety of specialists in multiple hospital settings a diagnosis of their ocular motility disorder had remained elusive. We describe their cases, outline the differential diagnosis and review the investigations performed which were influential in finally making a diagnosis.


Assuntos
Blefaroptose/complicações , Síndromes Miastênicas Congênitas/complicações , Síndromes Miastênicas Congênitas/diagnóstico , Transtornos da Motilidade Ocular/complicações , Encefalopatias/complicações , Criança , Inibidores da Colinesterase/uso terapêutico , Cistos/complicações , Diagnóstico Diferencial , Feminino , Humanos , Imageamento por Ressonância Magnética/métodos , Masculino , Síndromes Miastênicas Congênitas/tratamento farmacológico , Glândula Pineal/patologia , Brometo de Piridostigmina/uso terapêutico
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