1.
Palliat Med
; 22(2): 191-2, 2008 Mar.
Artigo
em Inglês
| MEDLINE
| ID: mdl-18372384
RESUMO
Opioid switching is increasingly practiced. This patient did not tolerate morphine, oxycodone or hydromorphone due to opioid toxicity. Finally switch to alfentanil was performed. The patient developed classical opioid withdrawal symptoms and signs from discontinuation of the hydromorphone. Administration of small aliqouts of this drug reversed the symptoms. The existance of incomplete cross tolerance between hydromorphone and alfentanil is demonstrated.