Assuntos
Acantoma , Neoplasias da Mama , Eczema , Mamoplastia , Neoplasias Cutâneas , Humanos , Feminino , Acantoma/diagnóstico , Acantoma/patologia , Mamilos/patologia , Neoplasias Cutâneas/patologia , Eczema/diagnóstico , Eczema/etiologia , Eczema/patologia , Neoplasias da Mama/diagnóstico , Neoplasias da Mama/patologiaAssuntos
Glucocorticoides/administração & dosagem , Imunossupressores/administração & dosagem , Síndromes Paraneoplásicas/tratamento farmacológico , Prednisona/administração & dosagem , Neoplasias Cutâneas/tratamento farmacológico , Tacrolimo/administração & dosagem , Timoma/tratamento farmacológico , Neoplasias do Timo/tratamento farmacológico , Administração Oral , Administração Tópica , Humanos , Masculino , Pessoa de Meia-Idade , Estadiamento de Neoplasias , Indução de Remissão , Neoplasias Cutâneas/etiologia , Timoma/patologia , Neoplasias do Timo/patologiaRESUMO
Eruptive melanocytic nevi have mainly been associated with blistering cutaneous diseases and with immunosuppression, particularly after renal allograft transplantation, hematological neoplasms, or HIV infection. Thus, immunosuppression has been suggested to increase the possibility of melanocyte proliferation. We report two cases of children with acute lymphoblastic leukemia who, after receiving chemotherapy, developed severe motor polyneuropathy, and sudden onset of multiple melanocytic nevi on the soles.
Assuntos
Antineoplásicos/efeitos adversos , Doenças do Pé/induzido quimicamente , Nevo/induzido quimicamente , Leucemia-Linfoma Linfoblástico de Células Precursoras/tratamento farmacológico , Neoplasias Cutâneas/induzido quimicamente , Criança , Pré-Escolar , Feminino , Humanos , MasculinoRESUMO
Four infants had soft, skin-colored nodules in the midline plantar region of the heels since birth. The lesions were asymptomatic, bilateral, and symmetric, and measured approximately 1 cm in diameter. Their size increased in proportion to the growth of the child. In three infants the lesions persisted at 1 year of age, while in the fourth they remained at age 12 years. The nodules were not associated with any other disease or abnormality. A review of the literature revealed only one Argentinean series comprising four cases, and two communications at international pediatric congresses by French and American authors who reported five and three cases, respectively. We describe four additional cases of precalcaneal congenital fibrolipomatous hamartoma and comment on their histopathologic and ultrastructural characteristics.
Assuntos
Tecido Adiposo/patologia , Dermatoses do Pé/patologia , Hamartoma/patologia , Tecido Adiposo/ultraestrutura , Diagnóstico Diferencial , Dermatoses do Pé/congênito , Hamartoma/congênito , Hamartoma/ultraestrutura , Humanos , Lactente , Recém-Nascido , Masculino , Microscopia EletrônicaRESUMO
Patellar tendon donor defect (PTDD) healing after patellar tendon autograft (PTA), was evaluated in 12 lambs (24 knees), by means of conventional histology, immunohistochemistry and image analysis. The results of this study indicate that the PTDD is replaced by a tissue that does not assume the histological characteristics of a normal patellar tendon. Both the Hoffa fat pad (HFP) and the paratenon play an important role in the healing process, although qualitative and quantitative chronological differences were found, which supports the concept of a "two-time process". The HFP initiates the repair process, and is the main active proliferative tissue compartment during the first week. Once the process is established, the paratenon and, in particular, its synovial lining, starts proliferative activity and virtually substitutes that of the HFP, which rapidly loses activity in a few days. Moreover, donor-site morbidity after PTA could be the result of histological changes in the patellar tendon and environs in only a few cases. We have found inflammatory and neural changes in the refilled PTDD that could explain the anterior knee pain after PTA. Likewise, we have observed loss of Golgi corpuscles in the refilled PTDD, which could lead to proprioceptive loss after ACL reconstruction with PTA. Finally, we have observed shrinkage of the PTDD scar that could contribute to the etiopathogenia of a patella infera.
Assuntos
Ligamento Cruzado Anterior/patologia , Patela/patologia , Tendões/patologia , Cicatrização , Animais , Ligamento Cruzado Anterior/cirurgia , Modelos Animais de Doenças , Feminino , Imuno-Histoquímica , Articulação do Joelho/patologia , Articulação do Joelho/cirurgia , Masculino , Patela/cirurgia , Prognóstico , Procedimentos de Cirurgia Plástica/métodos , Ovinos , Tendões/cirurgia , Doadores de Tecidos , Coleta de Tecidos e Órgãos , Transplante Autólogo , Cicatrização/fisiologiaRESUMO
The arterial pseudoaneurysm (AS) are a complication uncommon though very serious of the pancreatitis acute or chronic. We present the case of a male of 55 years with a pancreatitis chronic, developed within a pseudocyst pancreatic with break to left renal cell forming a hematoma perirrenal and perforation duodenal with massive gastrointestinal hemorrhage hypovolemic and death of the patient. We analyze theirs different forms of clinic presentation, the difficulties diagnostics found and the possible treatments that they could improve their results.