Your browser doesn't support javascript.
loading
Mostrar: 20 | 50 | 100
Resultados 1 - 20 de 23
Filtrar
1.
Rev Chilena Infectol ; 39(2): 117-125, 2022 04.
Artigo em Espanhol | MEDLINE | ID: mdl-35856983

RESUMO

BACKGROUND: In Chile, cervical cancer is the second leading cause of death from malignancy in women. The main causal agent of cervical cancer is the human papillomavirus (HPV). Compared with the general population, sex workers (SW) are at increased risk of acquiring HPV. AIM: To analyze the prevalence and genotypes of cervical and vaginal HPV in female SW attending a Sexual Control Centre. METHODS: A cross-sectional study was carried out on 97 women (19-70 years old). Two samples were taken per patient, one from exocervix and the other from vaginal walls. HPV DNA. was identified by polymerase chain reaction (PCR) and genotyping using specific probes for 32 types of HPV. RESULTS: The overall frequency of HPV was 45%, 41.2% in cervical carrier and 36.1% in vaginal carrier, 32% were co-infected, 63% of HPV were high-risk genotypes. The most frequent high-risk HPV was HPV 66 (12%), HPV 58 (9.3%), followed by HPV 16, HPV 59 and HPV 82 with the same frequency (8% each one). Thirty two (43%) of females were infected with multiple genotypes. CONCLUSION: HPV is frequent infection among SW. This is the first study in Chile on the prevalence and genotypes of HPV in sex workers.


Assuntos
Alphapapillomavirus , Infecções por Papillomavirus , Profissionais do Sexo , Neoplasias do Colo do Útero , Adulto , Idoso , Alphapapillomavirus/genética , Chile/epidemiologia , Estudos Transversais , DNA Viral/análise , DNA Viral/genética , Feminino , Genótipo , Humanos , Pessoa de Meia-Idade , Papillomaviridae/genética , Infecções por Papillomavirus/epidemiologia , Prevalência , Neoplasias do Colo do Útero/epidemiologia , Neoplasias do Colo do Útero/patologia , Adulto Jovem
2.
Rev. chil. infectol ; 39(2): 117-225, abr. 2022. ilus, tab
Artigo em Espanhol | LILACS | ID: biblio-1388345

RESUMO

INTRODUCCIÓN: En Chile, el cáncer de cuello uterino (CCU) es la segunda causa de muerte por neoplasias malignas en la mujer. El principal agente causal es el virus papiloma humano (VPH). Comparando con la población general, los o las trabajadoras(es) sexuales (TS) tienen alto riesgo de adquirir VPH. OBJETIVO: Analizar la prevalencia y genotipos del VPH cervical y vaginal en TS que se atienden en un Centro de Salud Sexual de Santiago, Chile. Pacientes y MÉTODO: Se realizó un estudio transversal en 97 mujeres TS, de 19 a 70 años de edad. Se obtuvieron dos muestras por paciente, una de exocérvix y otra de paredes vaginales. El ADN de VPH fue identificado por reacción de polimerasa en cadena (RPC) y su genotipo fue investigado para 32 tipos de VPH. RESULTADOS: La prevalencia de VPH global fue de 45%, observándose portación cervical en 41,2% y vaginal en 36,1%, con una coinfección de 32%. El 63% de las muestras tenía genotipos de alto riesgo. Los VPH de alto riesgo más frecuentes fueron el VPH 66 (12%), VPH 58 (9,3%), seguidos por VPH 16, VPH 59 y VPH 82 con igual frecuencia (8% c/u). Treinta y dos mujeres (43%) fueron infectadas con genotipos múltiples. CONCLUSIÓN: El VPH es una infección frecuente entre las TS. Este es el primer estudio en Chile sobre prevalencia y genotipos de VPH en TS.


BACKGROUND: In Chile, cervical cancer is the second leading cause of death from malignancy in women. The main causal agent of cervical cancer is the human papillomavirus (HPV). Compared with the general population, sex workers (SW) are at increased risk of acquiring HPV. AIM: To analyze the prevalence and genotypes of cervical and vaginal HPV in female SW attending a Sexual Control Centre. METHODS: A cross-sectional study was carried out on 97 women (19-70 years old). Two samples were taken per patient, one from exocervix and the other from vaginal walls. HPV DNA. was identified by polymerase chain reaction (PCR) and genotyping using specific probes for 32 types of HPV. RESULTS: The overall frequency of HPV was 45%, 41.2% in cervical carrier and 36.1% in vaginal carrier, 32% were co-infected, 63% of HPV were high-risk genotypes. The most frequent high-risk HPV was HPV 66 (12%), HPV 58 (9.3%), followed by HPV 16, HPV 59 and HPV 82 with the same frequency (8% each one). Thirty two (43%) of females were infected with multiple genotypes. CONCLUSION: HPV is frequent infection among SW. This is the first study in Chile on the prevalence and genotypes of HPV in sex workers.


Assuntos
Humanos , Feminino , Adulto , Pessoa de Meia-Idade , Idoso , Adulto Jovem , Neoplasias do Colo do Útero/patologia , Neoplasias do Colo do Útero/epidemiologia , Infecções por Papillomavirus/epidemiologia , Alphapapillomavirus/genética , Profissionais do Sexo , Papillomaviridae/genética , DNA Viral/análise , DNA Viral/genética , Chile/epidemiologia , Prevalência , Estudos Transversais , Genótipo
4.
J. oral res. (Impresa) ; 6(7): 182-185, July 2017. ilus
Artigo em Inglês | LILACS | ID: biblio-998799

RESUMO

Cervical necrotizing fasciitis (NF) is a soft tissue infection with a low incidence, characterized by rapid progression and high morbidity and mortality. The purpose of this report is to communicate the case of a patient diagnosed with cervical NF and its successful management. A 54-year-old male consulted after suffering from the condition for seven days. It was characterized by bilateral submandibular swelling, accompanied by fever, dysphagia, odynophagia, which were severely affecting the patient's general health. Physical examination revealed a painful, erythematous cervical swelling. A cervical computed tomography scan was performed, revealing a gaseous collection in the left mucosal pharyngeal space, extending to the glottis, associated with significant deep plane soft tissue emphysema onon the left side of the neck and with possible involvement of the danger space; pertinent lab findings include 19,190/uL leukocytes and 219mg/L CRP. Broad-spectrum antibiotic therapy was initiated with ceftriaxone and clindamycin. Exploratory surgery, lavage and drainage of the collected material were performed. Streptococcus anginosus was isolated by culture. The patient recovered appropriately showing improvement in clinical as well as in inflammatory parameters, being discharged on the ninth day. He is currently receiving periodical checkups in the surgery polyclinic


Assuntos
Humanos , Masculino , Fasciite Necrosante/microbiologia , Fasciite Necrosante/terapia , Ceftriaxona/uso terapêutico , Clindamicina/uso terapêutico , Tomografia Computadorizada por Raios X , Drenagem , Fasciite Necrosante/diagnóstico , Streptococcus anginosus , Antibacterianos/uso terapêutico , Pescoço
5.
Org Biomol Chem ; 15(25): 5357-5363, 2017 Jun 27.
Artigo em Inglês | MEDLINE | ID: mdl-28617493

RESUMO

Botrytis cinerea is a polyphagous fungal parasite which causes serious damage to more than 200 plant species and consequent economic losses for commercial crops. This pathogen produces two families of phytotoxins, the botryanes and botcinins, which are involved in the infection mechanism. The B. cinerea genome has provided a complete picture of the genes involved in the biosynthesis of its secondary metabolites. The botrydial biosynthetic gene cluster has been identified. This cluster consists of seven genes, where the genes BcBOT1, BcBOT3 and BcBOT4 encode three mono-oxygenases. A study of the Bcbot4Δ null mutant revealed that this mono-oxygenase was involved in the hydroxylation at C-4 of the probotryane skeleton (C-11 of the presilphiperfolane skeleton). A detailed study of the Bcbot4Δ null mutant has been undertaken in order to study the metabolic fate of the presilphiperfolan-8-ol intermediate biosynthesized by this organism and in particular by this strain. As a result three new presilphiperfolanes and three new cameroonanes have been identified. The results suggest that the absence of the oxygen function at C-11 of the presilphiperfolane skeleton permits rearrangement to a cameroonane whilst hydroxylation at C-11 precludes this rearrangement. It is possible that the interactions of the C-11 hydroxylated derivatives perturb the stereo-electronic requirements for the migration of the C-11:C-7 sigma bond to C-8.


Assuntos
Botrytis/metabolismo , Sesquiterpenos/metabolismo , Botrytis/genética , Cristalografia por Raios X , Modelos Moleculares , Conformação Molecular , Mutação , Sesquiterpenos/química
7.
J. oral res. (Impresa) ; 6(6): 160-164, June 2017. tab
Artigo em Inglês | LILACS | ID: biblio-907742

RESUMO

Aim: to evaluate, using the Scopus database, the input and output citation pattern in the year 2015 for documents published in the five main oral and maxillofacial (OMS) journals. Methods: All document types published over the 2013–2015 period by the five main OMS journals: BJOMS, JOMS, IJOMS, JCMFS and JCFS were included. Citation and referencing data were extracted from the advanced search of Scopus. Results: A total of 2303 documents were published by the journals in 2015, and 3253 documents published in 2015 cited documents published by the journals in 2013 and 2014. Self-citation was 13.19 percent for the five journals as a whole, and 1024 (31.49 percent) documents cited journals from within the group. A total of 36,972 references were included in documents published in 2015 in the journals. Self-referencing was 6.56 percent for all journals as a group, and 7524 (20.35 percent) documents were from the group itself. From the top-20 referenced and citing journals, the presence of plastic and reconstructive surgery, and head and neck (otolaryngology) surgery journals is clear. This pattern was not the same across all the journals under study. Conclusion: There appears to be a “medical versus dental” fragmentation of research in the specialty, over a fragmentation by regions or countries.


Assuntos
Bibliometria , Pesquisa em Odontologia , Publicações Periódicas como Assunto , Cirurgia Bucal
8.
Lasers Surg Med ; 49(4): 355-360, 2017 04.
Artigo em Inglês | MEDLINE | ID: mdl-27990665

RESUMO

BACKGROUND AND OBJECTIVE: Recently, the first diode laser with a wavelength of 755 nm for in-motion hair removal came on the market. The objective of this study was to check its efficacy, safety, and practicality under different options for its use. METHODS: A prospective study in a heterogeneous group of 56 patients who had hair removed from various areas of their bodies using three different treatment methods. Four sessions were scheduled in all cases, with a gap of 3 months between each session. Efficacy was assessed by counting of hairs per cm2 and the adverse effects in each session were recorded in detail in the patients' clinical histories. RESULTS: The three tested options achieved a significant reduction in the number of hairs (P < 0.0001). The average clearances achieved using the conventional method (HR), the in-motion method (SHR) and the stacking method were 75.5%, 70.1%, and 41.9%, respectively. The degree of satisfaction of the participants on a scale of 0-10 was 7.7, 8.1 and 6.8, respectively. Erythema and perifollicular edema, which are characteristic responses in laser hair removal, were observed. The incidence of burns was 1.33%. CONCLUSION: The 755-nm diode laser performed efficiently and safely in all the tested areas, using high total accumulated energy per surface unit. Based on our prior experience with other equipment, the results are promising. Lasers Surg. Med. 49:355-360, 2017. © 2016 Wiley Periodicals, Inc.


Assuntos
Remoção de Cabelo/instrumentação , Terapia a Laser , Lasers Semicondutores/uso terapêutico , Adolescente , Adulto , Feminino , Remoção de Cabelo/efeitos adversos , Humanos , Masculino , Pessoa de Meia-Idade , Estudos Prospectivos , Resultado do Tratamento , Adulto Jovem
9.
Fungal Genet Biol ; 96: 33-46, 2016 11.
Artigo em Inglês | MEDLINE | ID: mdl-27721016

RESUMO

Botrydial (BOT) is a non-host specific phytotoxin produced by the polyphagous phytopathogenic fungus Botrytis cinerea. The genomic region of the BOT biosynthetic gene cluster was investigated and revealed two additional genes named Bcbot6 and Bcbot7. Analysis revealed that the G+C/A+T-equilibrated regions that contain the Bcbot genes alternate with A+T-rich regions made of relics of transposable elements that have undergone repeat-induced point mutations (RIP). Furthermore, BcBot6, a Zn(II)2Cys6 putative transcription factor was identified as a nuclear protein and the major positive regulator of BOT biosynthesis. In addition, the phenotype of the ΔBcbot6 mutant indicated that BcBot6 and therefore BOT are dispensable for the development, pathogenicity and response to abiotic stresses in the B. cinerea strain B05.10. Finally, our data revealed that B. pseudocinerea, that is also polyphagous and lives in sympatry with B. cinerea, lacks the ability to produce BOT. Identification of BcBot6 as the major regulator of BOT synthesis is the first step towards a comprehensive understanding of the complete regulation network of BOT synthesis and of its ecological role in the B. cinerea life cycle.


Assuntos
Aldeídos/metabolismo , Botrytis/genética , Compostos Bicíclicos com Pontes/metabolismo , Proteínas Fúngicas/metabolismo , Regulação Fúngica da Expressão Gênica , Família Multigênica , Fatores de Transcrição/metabolismo , Sequência Rica em At , Botrytis/metabolismo , Botrytis/patogenicidade , Elementos de DNA Transponíveis , DNA Fúngico , Proteínas Fúngicas/genética , Proteínas Nucleares/genética , Proteínas Nucleares/metabolismo , Virulência
10.
Rev. chil. cir ; 68(5): 394-399, oct. 2016.
Artigo em Espanhol | LILACS | ID: lil-797354

RESUMO

Los ensayos clínicos controlados son el diseño por excelencia de la medicina basada en la evidencia. Sin embargo, son el final de un largo camino que comienza con interrogantes o hipótesis que se desprenden de otros tipos de diseños. Algunos de los diseños que se encuentran en este camino son los estudios observacionales analíticos y los estudios de experimentacion en animales. Para que la información entregada por estos tipos de diseños sea de buena calidad, requieren cumplir con estándares mínimos en su reporte, y para esto es que se han diseñado las pautas STROBE y ARRIVE, respectivamente. La iniciativa STROBE fue formada el 2004 tomando como base la experiencia CONSORT, con el objetivo de facilitar la comunicación de estudios observacionales; incluye 22 ítems agrupados en 6 dominios (título/resumen, introducción, método, resultados, discusión y otra información). La pauta ARRIVE comenzó su elaboración durante el 2009, para ser finalmente publicada durante el 2010; incluye 20 ítems, los cuales se agrupan en 5 dominios (título/resumen, introducción, método, resultados y discusión). El uso de estas pautas ha llevado a una mejora en la calidad del reporte de estos tipos de diseños. Sin embargo, la calidad metodológica de muchos estudios continúa siendo subóptima, por lo que se requiere además de otras estrategias para la mejora global de este constructo. Este tercer artículo de la serie describe ambas pautas de chequeo para su uso por parte de los autores de la REVISTA CHILENA DE CIRUGÍA, con el fin de lograr una mejora de sus artículos de una forma simple y eficiente.


Controlled clinical trials are the ultimate design of evidence-based medicine. However, they are the end of a long journey that begins with questions or hypotheses that arise from other types of designs. Some of the designs found in this way are analytical observational studies and experimental studies in animals. To reach a good quality standard by these types of designs, they are required to comply with minimum standards in his report, for this is that they have designed the STROBE and ARRIVE checklists respectively. The STROBE checklist was developed in 2004 based on the CONSORT experience, in order to facilitate the reporting of observational studies, includes 22 items grouped into 6 domains (title / abstract, introduction, methods, results, discussion and other information). The ARRIVE checklist began developing in 2009, to be finally published in 2010, includes 20 items, which are grouped as 5 domain (title / abstract, introduction, methods, results and discussion). Using these checklists has led to improved quality report these types of designs. However the methodological quality of many studies remains suboptimal, so it also requires other strategies for overall improvement of this construct. This third article in the series describes both checklists for use by the authors of the REVISTA CHILENA DE CIRUGÍA, in order to achieve an improvement of its items in a simple and efficient way.


Assuntos
Controle de Qualidade , Experimentação Animal , Estudos Observacionais como Assunto/normas , Lista de Checagem , Relatório de Pesquisa/normas , Publicações Periódicas como Assunto/normas , Medicina Baseada em Evidências/normas
11.
Rev. chil. cir ; 68(5): 400-404, oct. 2016.
Artigo em Espanhol | LILACS | ID: lil-797355

RESUMO

Los ensayos clínicos controlados representan el diseño más destacado en la investigación biomédica. Sin embargo, existen otros diseños metodológicos que aportan información relevante para la medicina basada en la evidencia: los estudios sobre precisión de pruebas diagnósticas y reportes de caso. Al igual que con otros diseños, estos necesitan cumplir con estándares de calidad en su reporte, para lo que se han diseñados las pautas STARD y CARE, respectivamente. La pauta STARD comenzó a desarrollarse en 1999, siendo publicada en 2003, e incluye 25 ítems agrupados en 5 dominios (título/resumen/palabras clave, introducción, métodos, resultados, discusión). La pauta CARE se elaboró de acuerdo a la Guía para Desarrolladores de Guías de Reporte de Investigación en Salud, siendo publicada en 2013, e incluye 13 ítems, sin dominios declarados y que es de uso general para todos los ámbitos de la medicina. Así como con otras pautas de chequeo, el uso de STARD se ha asociado a una mejora en la calidad del reporte de estudios sobre precisión diagnóstica. En el caso de CARE, es necesario evaluar con el paso de los años su impacto en la calidad de los reportes de caso. Este último artículo de la serie describe ambas pautas de chequeo para su uso por parte de los autores de la REVISTA CHILENA DE CIRUGÍA, con el fin de lograr una mejora de sus artículos de una forma simple y eficiente.


Controlled clinical trials represent the design highlight in biomedical research. However, there are other methodological designs that provide relevant information for evidence-based medicine: studies of diagnostic test accuracy and case reports. As with other designs, they need to meet quality standards in their reporting, that is the reason for the design of STARD and CARE checklists, respectively. The STARD checklist began to develop in 1999, being published in 2003, it includes 25 items grouped into five domains (title / abstract / keywords, introduction, methods, results, discussion). The CARE checklist was made according to the Guidance for Developers of Health Research Reporting Guidelines, was published in 2013, it includes 13 items, without declared domains and is commonly used for all areas of medicine. As with other checklist, the use of STARD has been associated with an improvement in quality report of studies on diagnostic accuracy. In the case of CARE, it is necessary to assess over the years its impact on quality of case reports. This last article in the series describes both checklists for use by the authors of the REVISTA CHILENA DE CIRUGÍA, in order to achieve an improvement in their articles in a simple and efficient way.


Assuntos
Humanos , Controle de Qualidade , Testes Diagnósticos de Rotina/normas , Lista de Checagem , Relatório de Pesquisa/normas , Publicações Periódicas como Assunto/normas , Editoração , Ensaios Clínicos Controlados como Assunto/normas , Medicina Baseada em Evidências/normas
12.
Plast Surg (Oakv) ; 24(1): 35-40, 2016.
Artigo em Inglês | MEDLINE | ID: mdl-27054137

RESUMO

BACKGROUND: Upper arm deformities secondary to weight loss or senile elastosis have led to an increased demand for aesthetic contouring procedures. OBJECTIVE: To objectively assess whether, in Teimourian high-grade upper arm remodelling, laser-assisted lypolysis (LAL) alone could result in patient satisfaction. METHODS: Between 2012 and 2013, 22 patients were treated for excessive upper arm fat (Teimourian grade III and IV) solely with LAL. The laser used in the present study was a 1470 nm diode laser (Alma Lasers, Israel) with the following parameters: continuous mode, 15 W power and transmission through a 600 µm optical fibre. Previous mathematical modelling suggested that 0.1 kJ was required to destroy 1 mL of fat. Patients were asked to complete a satisfaction questionnaire. The arm circumference was measured pre- and postoperatively. Treatment parameters, adverse effects and outcomes were recorded. RESULTS: Pain during the anesthesia and discomfort after the procedure were minimal. Complications included ecchymoses and prolonged edema. The mean (± SD) arm circumference decreased 5.5±1.0 cm in the right arm (P<0.01) and 5.2±1.1 cm in the left arm (P<0.01) in grade III patients and 4.9±1.1 cm in the right arm (P<0.01) and 4.9±1.1 cm in the left arm (P<0.01) in grade IV patients. Although the circumference of both arms significantly decreased in grade III and grade IV patients, the skin tightening remained incomplete. Overall, the average opinion of treatment was poor for both patients and investigators. Of the 22 patients, only nine (41%) would recommend this treatment. CONCLUSION: LAL for upper arm remodelling is not sufficient to ensure full skin tightening for patients with Teimourian grades III and IV upper arm deformities. A complementary surgery is mandatory for grades III and IV.


ETAT DE L'ART: Les déformations des bras attribuables à une perte de poids ou à l'élastose sénile ont suscité l'augmentation des demandes d'interventions de redrapage esthétique. OBJECTIF: Evaluer objectivement si la lipolyse laser (LL) seule, utilisée pour le redrapage des bras de grades Teimourian III et IV, permet la satisfaction des patients. MATÉRIEL ET MÉTHODES: Entre 2012 et 2013, 22 patients ont été traités par LL seule pour le redrapage des bras de grades Teimourian III et IV. Le laser diode 1470 nm (Alma Lasers, Israël) était utilisé avec les paramètres suivants : mode continu, puissance de 15W, et transmission par fibre optique de 600µm. Selon notre modélisation antérieure, 0,1 kJ était nécessaire pour détruire 1 mL de tissus adipeux. Les patients ont été invités à remplir un questionnaire de satisfaction. La circonférence des bras étaient consignée avant et après intervention. Les paramètres laser requis, les complications, et les résultats étaient enregistrés de manière prospective. RÉSULTATS: La douleur pendant l'anesthésie et l'inconfort après l'intervention étaient minimes avec cette technique. Les complications incluaient des ecchymoses et un oedème prolongé. La circonférence moyenne des bras a diminué de 5,5±1,0 cm au bras droit (p<0,01) et 5,2±1,1 cm au bras gauche (p<0,01) chez les patients de grade Teimourian III, et de 4,9±1,1 cm au bras droit (p<0,01) et 4,9±1,1 cm au bras gauche (p<0,01) chez les patients de grade IV. Même si la circonférence des deux bras a diminué considérablement pour les grades Teimourian III et IV, le redrapage cutané est demeuré incomplet. En moyenne, le résultat est jugé insatisfaisant tant pour les patients que pour les investigateurs. Sur les 22 patients, seuls neuf (41%) recommanderaient le traitement. CONCLUSION: La lipolyse laser est insuffisante pour assurer un redrapage complet des déformations des bras de grades Teimourian III et IV. Une chirurgie complémentaire reste nécessaire dans ces cas-là.

13.
Lasers Surg Med ; 47(2): 173-9, 2015 Feb.
Artigo em Inglês | MEDLINE | ID: mdl-25663083

RESUMO

INTRODUCTION: Hyperhidrosis is a debilitating problem that is not only uncomfortable and inconvenient, but also embarrassing in work and social situations. In spite of the availability of several options for the treatment of axillary hyperhidrosis, recently, there has been an increasing interest in the use of laser therapy. This study aims to evaluate the efficacy of a laser diode device emitting at wavelengths of 924 and 975 nm and classical curettage either alone, simultaneously or in combination. MATERIAL AND METHODS: A randomized prospective controlled trial was carried out on 100 patients divided into four groups, each with a different protocol: Laser alone at 975 nm (group 1), laser alone at 924/975 nm simultaneously (group 2), curettage alone (group 3), and finally laser at 924/975 nm followed by curettage (group 4). HDSS, starch test and GAIS were used to assess treatment efficacy. The follow-up extended to one year. Statistical analysis (SPSS) was used to determine the accuracy of the results. RESULT: Two patients of group 1 experienced burns during treatment, which took over a month to heal. This group of patients achieved the worst results: The starch test scale results after treatment were 2.48 ± 0.51 and 2.76 ± 0.44 (at 1 and 12 months). The GAIS results were 1.04 ± 0.35 and 0.92 ± 0.28 (1 and 12 months). In group 2 the starch test scale results after treatment were 1.36 ± 0.49 and 1.48 ± 0.51 (at 1 and 12 months). The GAIS results were 2.36 ± 0.49 and 2.72 ± 0.46 (at 1 and 12 months). In group 3, the starch test scale results after treatment were 1.56 ± 0.51 and 1.76 ± 0.60 (at 1 and 12 months), which corresponds to small to substantially smaller dark areas. The GAIS results were 2.28 ± 0.46 and 2.64 ± 0.49 (at 1 and 12 months). The best results were obtained in group 4: HDSS scores were reduced from 3.88 ± 0.33 before treatment to 1.24 ± 0.44 and 0.48 ± 0.51 at the 1 and 12 months controls. The starch test scale results after treatment were 0.40 ± 0.50 and 0.44 ± 0.51 (at 1 and 12 months). The GAIS results were 3.72 ± 0.54 and 3.76 ± 0.44 (at 1 and 12 months). CONCLUSION: In this study, the laser at 924/975 nm combined with curettage was determined to be the optimal treatment option of those tested for axillary hyperhidrosis. This treatment was safe, with few side effects and improvement that persisted to one year follow-up.


Assuntos
Hiperidrose/terapia , Terapia a Laser/métodos , Lasers Semicondutores/uso terapêutico , Axila , Terapia Combinada , Curetagem , Seguimentos , Humanos , Hiperidrose/diagnóstico , Estudos Prospectivos , Índice de Gravidade de Doença , Método Simples-Cego , Fatores de Tempo , Resultado do Tratamento
14.
J Cosmet Laser Ther ; 17(1): 31-6, 2015 Feb.
Artigo em Inglês | MEDLINE | ID: mdl-25286033

RESUMO

BACKGROUND: Since the first studies by Apfelberg in 1994 and the mathematical model of Mordon introduced in 2004, laser-assisted lipolysis (LAL) has been on the rise. In a previous study, we presented our results in patients treated with LAL for Rohrich type I to III aging neck. The average cervicomental angle decreased from 152.6 ± 5.9 to 123.6 ± 8.8 degrees after LAL. This demonstrated a systematic decrease in fat thickness, and improved skin tightening. OBJECTIVE: This new protocol focuses solely on LAL in the Rohrich type IV aging neck. METHODS: Between June 2012 and February 2013, a prospective study was performed on 10 patients treated with LAL for Rohrich type IV aging neck. The laser used in this study was a 1470 nm diode laser (Alma Lasers, Caesarea, Israel). Laser energy was transmitted through a 600 µm optical fiber and delivered in a continuous mode, at 15 W power. Previous mathematical modeling suggested that 0.1 kJ was required in order to destroy 1 ml of fat. Patients were asked to fill out a satisfaction questionnaire. The cervicomental angle was measured 6 months postoperatively, and compared with the preoperative values. RESULTS: No seromas were observed, but prolonged edema was observed in two patients. Pain during anesthesia and discomfort after the procedure were minimal. The average cervicomental angle decreased from 191.5 ± 5.7 to 164.9 ± 14.2 degrees (p < 0.01). This demonstrated a systematic decrease in fat thickness and improved skin tightening. Even though the cervicomental angle was higher than 140° in each case, the investigators, in agreement with the patients, decided to perform a complementary surgery with platysma muscle advancement and plication six months after LAL, in only two of the ten patients. This complementary surgery led to a mean cervicomental angle of 140.2 ± 11.4, and fair satisfaction of both patients and investigators. CONCLUSION: LAL alone appears insufficient for complete remodeling in Rohrich type IV aging neck. While LAL alone is sufficient for Grade I to III, a complementary surgery must be added for Grade IV.


Assuntos
Lasers Semicondutores/uso terapêutico , Lipectomia/métodos , Gordura Subcutânea/cirurgia , Idoso , Feminino , Humanos , Lasers Semicondutores/efeitos adversos , Lipectomia/efeitos adversos , Lipectomia/instrumentação , Pessoa de Meia-Idade , Pescoço/cirurgia , Dor Pós-Operatória/etiologia , Satisfação do Paciente , Reoperação
15.
J. oral res. (Impresa) ; 3(2): 109-113, Jun. 2014. ilus, tab
Artigo em Inglês | LILACS | ID: lil-727969

RESUMO

In recent years, several bibliometric evaluations covering various clinical specialties in dentistry have been carried out. However, there are no recent reports in the area of education. The aim of this brief report is to describe the bibliometric profile of dental education journals included in the Web of Science databases (ISI). A bibliometric study of the two dental education journals included in the Science Citation Index expanded database from Web of Science was conducted. Analyze results and Citation Report tools were used to consider the following variables for the total of articles by journal: amount of papers, publication year, affiliated organizations and countries, keywords, number of citations and most cited articles. A total of 1,279 articles were analyzed: Journal of Dental Education (JDE) with 956 papers (74.75 percent) and European Journal of Dental Education (EJDE) with 323 papers (25.25 percent). The United States had the largest number of articles (695), mainly in JDE, and England (110) in EJDE. Consistently, American institutions have the highest productivity in the area. The more used keywords were learning and curriculum. Given the influence that dental education has in all the areas of the profession, it is necessary to further investigate and focus on the quality of research in this area.


En los últimos años se ha realizados diversas evaluaciones bibliométricas en odontología, cubriendo varias especialidades clínicas. Sin embargo, no existen reportes recientes en el área educativa. El objetivo de este breve reporte es describir el perfil bibliométrico de las revistas de educación dental incluidas en las bases de datos de Web of Science (ISI). Se realizó un estudio bibliométrico de las 2 revistas de educación dental incluidas en la base de datos Science Citation Index Expanded de Web of Science. Utilizando las herramientas Analize Results y Citation Report se obtuvieron las siguientes variables: Cantidad de documentos, Año de publicación, Organizaciones y Países en la afiliación, Palabras clave, Número de citas y Artículos más citados; para el total de los documentos y separados por revista. Se analizaron 1.279 documentos: Journal of Dental Education (JDE) con 956 documentos (74,75 por ciento) y European Journal of Dental Education (EJDE) con 323 documentos (25,25 por ciento). Estados Unidos tiene la mayor cantidad de artículos (695), principalmente en JDE, e Inglaterra (110) en EJDE; de igual forma son las instituciones estadounidenses las que tienen una mayor productividad en el área. Las palabras claves más utilizadas fueron aprendizaje y currículum. Dada la influencia que tiene la educación dental en todos los ámbitos de la profesión, es necesario seguir investigando y centrarse en la calidad de la investigación en esta área.


Assuntos
Humanos , Bibliometria , Educação em Odontologia , Publicações Periódicas como Assunto , Bases de Dados Bibliográficas
16.
Int. j. odontostomatol. (Print) ; 8(1): 69-75, Apr. 2014. ilus
Artigo em Espanhol | LILACS | ID: lil-711549

RESUMO

El proceso de medición consiste en asignar valores numéricos a características del paciente, un nivel de daño, certeza diagnóstica de la enfermedad, entre otros. Sin embargo, existen fenómenos complejos que incluyen conceptos más amplios que requieren de la creación y validación de instrumentos psicométricos para su registro. El objetivo de esta revisión es presentar los conceptos de validez y confiabilidad de instrumentos de medición aplicados en Odontología. Se expone la definición en salud de variables directas e indirectas, la importancia del uso de instrumentos psicométricos, la definición de Validez y Confiabilidad de un instrumento y sus distintas clasificaciones (validez de contenido, de criterio y de constructo; confiabilidad del instrumento y del observador). Además, se presenta algunos ejemplos del proceso de validación de instrumentos, su metodología y forma de análisis de los resultados. De esta forma, presentamos los tópicos necesarios para comprender el proceso de medición usado en nuestro quehacer clínico o en investigación odontológica, con el fin de identificar los instrumentos adecuados (validos y confiables) para nuestras necesidades


The measurement process consists in assigning numerical values to the patient's characteristics, level of injury, diagnostic certainty of the disease, among others. However, there are complex phenomena that include broader concepts, which require the creation and validation of psychometric instruments for its measurement. The aim of this review is to present the concepts of validity and reliability of the instruments used in Dentistry. It exposes health definition of direct and indirect variables, the importance of using psychometric instruments, the definition of Validity and Reliability of an instrument and its different classifications (content validity, criterion and construct; reliability of the instrument and the observer). Furthermore, it presents some examples of the validation process of an instrument, its methodology and analysis of the results. Thus, we present the topics necessary to understand the measurement process used in our clinical work or dental research in order to identify appropriate instruments, considered valid and reliable for our needs


Assuntos
Humanos , Pesquisa em Odontologia/instrumentação , Odontologia Baseada em Evidências , Psicometria , Reprodutibilidade dos Testes
17.
J. oral res. (Impresa) ; 3(1): 36-39, mar. 2014. graf, tab
Artigo em Inglês | LILACS | ID: lil-727825

RESUMO

The aim of this study is to determine the geographic origin and level of evidence (LE) of articles published in Chilean dental journals during 2012. The target population for the bibliometric study was articles published in exclusively-scientific Chilean dental journals. These variables were analyzed: journal, area, language, country, region, design, scenario, and LE. A total of 120 articles were published in four journals: International Journal of Odontostomatology (IJOS=59), Revista Clínica de Periodoncia, Implantología y Rehabilitación Oral (PIRO=28), Journal of Oral Research (JOR=18), and Revista Dental de Chile (RDC=15). From the total, 80.83 percent were published in Spanish and 70 percent had a Chilean affiliation. Most publications corresponded to areas of pathology (21) others (20) and prosthodontics (20). None of the articles was Level 1 Evidence, 6.49 percent was 2b, 14.29 percent was 2c, 63.64 percent was 4, and 15.58 percent was 5. Chilean dental journals mainly publish articles of domestic origin and low LE.


El objetivo de esta investigación es determinar el origen y nivel de evidencia (NE) de los artículos publicados en las revistas odontológicas chilenas durante el año 2012. Estudio bibliométrico, la población objetivo fueron todos los artículos publicados en revistas dentales chilenas de orientación exclusivamente científica. Se analizaron variables: Revista, Área, Idioma, País, Región, Diseño, Escenario y NE. Se hallaron 120 artículos publicados en cuatro revistas: International Journal of Odontostomatology (IJOS = 59), Revista Clínica de Periodoncia, Implantología y Rehabilitación Oral (PIRO = 28), Journal of Oral Research (JOR = 18) y Revista Dental de Chile (RDC = 15). El 80.83 por ciento de los artículos fue publicado en español y el 70 por ciento corresponden a autores chilenos. La mayor cantidad de publicaciones correspondieron a las áreas de Patología (21), Otra (20) y Prostodoncia (20). No se hallaron artículos de NE 1, 6.49 por ciento fue 2b, 14.29 por ciento fue 2c, 63,64 por ciento fue 4 y 15.58 por ciento fue 5. Las revistas odontológicas chilenas publican principalmente artículos de origen nacional y con un bajo NE.


Assuntos
Bibliometria , Odontologia Baseada em Evidências , Saúde Bucal , Publicações Periódicas como Assunto , Chile , Geografia , Afiliação Institucional
18.
Phlebology ; 29(10): 658-66, 2014 Dec.
Artigo em Inglês | MEDLINE | ID: mdl-23989971

RESUMO

OBJECTIVE: To assess the efficacy and safety of a new method of clearing varicose veins in the long term. It consists of applying the long-pulsed Nd:YAG laser following the injection of polidocanol microfoam, in two consecutive sessions, treating both legs in full in each session. METHOD: Randomized, Polidocanol-controlled, blind evaluation clinical trial comparing the results between 79 legs treated with Polidocanol and 517 treated with Polidocanol + Laser. Photographs were taken preoperatively and at three months, two years and three years after treatment, as well as patient self-assessments. RESULTS: Polidocanol + Laser is much more effective than polidocanol microfoam in clearing venulectasias with a diameter under 4 mm (p < 0.001). After three years, clearing percentages of 89% (Class I veins), 94% (Class II veins) and 95% (Class III veins) are observed, in comparison to 15%, 18% and 17%, respectively when only polidocanol was applied. No unexpected adverse effects were found and 86% of patients stated they were Satisfied or Very Satisfied. CONCLUSION: The method leads to safe, fast and apparently permanent results. The treatment session lasts less than 1 h, and could become a first-choice treatment for the removal of all types of varicose veins with a diameter under 4 mm.


Assuntos
Terapia a Laser/métodos , Polietilenoglicóis/uso terapêutico , Soluções Esclerosantes/uso terapêutico , Escleroterapia , Telangiectasia/terapia , Varizes/terapia , Adulto , Idoso , Terapia Combinada , Feminino , Seguimentos , Humanos , Terapia a Laser/efeitos adversos , Lasers de Estado Sólido , Perna (Membro)/irrigação sanguínea , Pessoa de Meia-Idade , Polidocanol , Escleroterapia/efeitos adversos , Método Simples-Cego , Telangiectasia/tratamento farmacológico , Resultado do Tratamento , Varizes/tratamento farmacológico , Adulto Jovem
19.
J. oral res. (Impresa) ; 2(1): 18-22, abr. 2013. tab
Artigo em Espanhol | LILACS | ID: lil-708321

RESUMO

Introducción: Caracterizar la producción científica personal, institucional o nacional es una necesidad para comprender y mejorar la generación de conocimiento. El objetivo de este estudio es describir el perfil bibliométrico de las publicaciones ISI de la Facultad de Odontología de la Universidad de Concepción en el período 1989-2012. Material y método: Estudio bibliométrico. Se realizó una búsqueda en la plataforma Web of Knowledge de Thomson Reuters para la base de datos Science Citation Index Expanded, respecto de la productividad científica de la Facultad de Odontología de la Universidad de Concepción entre 1989 y 2012. Las variables analizadas fueron número de publicaciones, citaciones por año, revistas en las que se publicó, autores, instituciones y países de coautoría. Resultados: Se identificaron 39 artículos. Fueron citados en 266 oportunidades (6,82 citas por documento e índice-h de 10). Los artículos fueron publicados en Oral Surgery Oral Medicine Oral Pathology Oral Radiology and Endodontology (21,9 por ciento), Journal of Oral Pathology Medicine (12,2 por ciento) y International Journal of Morphology (7,3 por ciento). Los autores más productivos corresponden a Rojas(13), Martínez (11) y Brethauer (9). El 48,72 por ciento de las publicaciones se concentraron en el último quinquenio y el 69,23 por ciento en el último decenio. Conclusión: La producción científica de la Facultad de Odontología de la Universidad de Concepción es baja, observándose un aumento de esta durante los últimos 5 años.


Aim: To characterize personal, institutional or national scientific production is a need to understand and improve the generation of knowledge. The aim of this study is to describe the bibliometric profile of ISI publications related of Universidad de Concepción School of Dentistry during 1989-2012 time span Matherial and methods: Bibliometric study. A search on Web of Knowledge of Thomson Reuters for Science Citation Index Expanded database was perfomed, about the scientific productivity of Universidad de Concepción School of Dentistry during 1989-2012 period. The analyzed variables were the number of publications, cites, magazines on which they were published, authors, institutions and co author countries. Results: Thirty nine articles were identified. These articles were cited in 266 opportunities (6,82 cites per article and h-index of 10). In relation with journals, stands out Oral Surgery Oral Medicine Oral Pathology Oral Radiology and Endodontology (21,9 percent), Journal of Oral Pathology Medicine (12,2 percent), and International Journal of Morphology (7,3 percent). More productive authors were Rojas (13), Martínez (11) y Brethauer (9). 48,72 percent of publications was concentrated in last five-years and 69,23 percent in last ten years. Conclusions: Universidad de Concepción School of Dentistry scientific production is poor, being observed an increase during the last 5 years.


Assuntos
Bibliometria , Odontologia , Publicações Periódicas como Assunto , Chile
20.
Rev Col Bras Cir ; 40(1): 23-31, 2013.
Artigo em Espanhol | MEDLINE | ID: mdl-23538535

RESUMO

OBJECTIVES: To evaluate efficacy of laser lipolysis in the treatment of gynecomastia to correct breast volume, flaccidity and excess skin without its excision. METHODS: Prospectively, 32 patients with gynecomastia under tumescent anaesthesia and sedation underwent laser lipolysis with 980 nm diode laser, 15W continuous emission and 8 to 12 kJ energy per breast. Externally cold air was used to protect the skin. No drainages were used but a compressive bandage. Patients evaluated results on a VAS scale. Two doctors evaluated results comparing before and 6 month after photographs and also measured the areola and chest diameter. RESULTS: Twenty three patients considered results as Very Good, 7 Good and 2 Fair Cutaneous retraction of the areola was noticeable one month after the surgery and was maximum 6 months after. Evaluation by doctors was 26 Very Good, 5 Good and 1 Fair. There were no burns, ischemia or lesions in areolas or nipples. CONCLUSION: Laser assisted liposuction is a simple and efficacious technique, barely traumatic and permits a rapid reincorporation to normal activities.


Assuntos
Ginecomastia/cirurgia , Terapia a Laser , Lipectomia/métodos , Adulto , Humanos , Masculino , Pessoa de Meia-Idade , Estudos Prospectivos , Pele , Resultado do Tratamento , Adulto Jovem
SELEÇÃO DE REFERÊNCIAS
DETALHE DA PESQUISA