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1.
Eur J Cardiothorac Surg ; 40(4): 1022-4, 2011 Oct.
Artigo em Inglês | MEDLINE | ID: mdl-21353583

RESUMO

As previously well described in the literature, the intercostal muscle (ICM) flap can be used to buttress bronchial stumps following lung resection. We describe a harvesting technique of ICM flap which enabled a bi-lobectomy to be avoided in a patient with poor pulmonary function. The Key to this technique is the preservation of the neurovascular bundle. Therefore the flap is not divided anteriorly thereby differentiating it from any previous technique described.We have called it the 'bucket handle' technique, which was used to repair an intra-operative tear in bronchus intermedius. Its efficacy was tested to the full when the patient developed severe adult respiratory distress syndrome (ARDS) secondary to pseudomonas pneumonia and required high-pressure mechanical ventilation. This case demonstrates that ICM flap is an effective buttress to bronchial stumps or repairs and offers reassurance for optimal outcome due to its intact vascular pedicle.


Assuntos
Brônquios/lesões , Brônquios/cirurgia , Músculos Intercostais/transplante , Retalhos Cirúrgicos , Idoso , Broncografia/métodos , Feminino , Humanos , Neoplasias Pulmonares/secundário , Neoplasias Pulmonares/cirurgia , Excisão de Linfonodo/efeitos adversos , Tomografia Computadorizada por Raios X
2.
Oxid Med Cell Longev ; 3(3): 199-205, 2010.
Artigo em Inglês | MEDLINE | ID: mdl-20716944

RESUMO

The aim of this study was to investigate if there was a link between the relaxant responses in saphenous vein (SV) and internal mammary artery (IMA) segments obtained from patients undergoing coronary artery bypass grafting and the patients' cardiovascular risk factors. Endothelium-(in)dependent relaxations were assessed by isometric tension studies. Endothelium-dependent relaxant responses were greater in IMA than SV and gender, smoking profile and history of hypertension but not diabetes appeared to have an influence on these responses. Endothelium-dependent relaxant responses in both IMA and SV were greater in males than females and relaxant responses in IMA segments were attenuated in smokers, whereas the opposite effect was noted in SV segments. Endothelium-dependent relaxant responses in SV were lower in patients with hypertension. Endothelium-independent relaxant responses were greater in IMA than SV. Endothelium-independent responses were greater in male patients' SV segments, but gender played no role in IMA segments. Diabetes had no effect on endothelium-independent responses in IMA, but SV segments from diabetic patients had greater responses. Neither conduit's endothelium-independent response was affected by hypertensive status. The relationship between risk factor status and endothelial responses is multifactorial, with gender, hypertension, diabetes and smoking status all contributing.


Assuntos
Diabetes Mellitus/fisiopatologia , Endotélio Vascular/fisiologia , Hipertensão/fisiopatologia , Artéria Torácica Interna/fisiologia , Veia Safena/fisiologia , Vasodilatação/fisiologia , Adulto , Idoso , Idoso de 80 Anos ou mais , Ponte de Artéria Coronária , Endotélio Vascular/fisiopatologia , Feminino , Humanos , Masculino , Artéria Torácica Interna/fisiopatologia , Pessoa de Meia-Idade , Veia Safena/fisiopatologia , Fatores Sexuais , Fumar/efeitos adversos
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