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1.
J Cancer Res Ther ; 18(3): 849-852, 2022.
Artigo em Inglês | MEDLINE | ID: mdl-35900574

RESUMO

Metastatic malignant melanoma (MMM) of the oral cavity is extremely rare which generally presents in the setting of disseminated disease and have extremely poor prognosis. The most common site for MMM in the oral cavity is tongue followed by buccal mucosa for soft-tissue lesions and posterior mandible for bone involving lesions. Primary tumor sites of oral MMM are usually cutaneous lesions of the trunk, head and neck, limbs, and nasal septum mucosa. Patients bearing this diagnosis face median survival time of approximately 9 months with a probability of surviving 5 years after the initial presentation is <5%; hence, an early detection and treatment for the primary and metastatic lesion is crucial. Here, we present an unusual case of MMM of oral cavity involving gingiva and alveolar bone of the mandibular anterior region metastasizing from a primary lesion on the foot.


Assuntos
Melanoma , Segunda Neoplasia Primária , Humanos , Mandíbula/diagnóstico por imagem , Mandíbula/patologia , Melanoma/patologia , Mucosa Bucal/patologia , Segunda Neoplasia Primária/patologia , Prognóstico
2.
Contemp Clin Dent ; 4(2): 181-5, 2013 Apr.
Artigo em Inglês | MEDLINE | ID: mdl-24015006

RESUMO

INTRODUCTION: Oral lichen planus (OLP) is a relatively common inflammatory mucocutaneous disorder that frequently involves the oral mucosa. The clinical presentation of OLP ranges from mild painless white keratotic lesions to painful erosions and ulcerations. An important complication of OLP is the development of oral squamous cell carcinoma, which led the World Health Organization (WHO) to classify OLP as a potentially malignant disorder. The demographic and clinical characteristics of OLP have been well-described in several relatively large series from developed countries, whereas such series from developing countries are rare. OBJECTIVE: The objective of this retrospective study was to investigate the epidemiological and clinical characteristics of 128 OLP patients in rural population of India. MATERIALS AND METHODS: In this study, the diagnostic criteria proposed by van der Meij et al. in 2003 based on the WHO definition of OLP were used to identify cases. RESULTS: In 128 patients, M:F ratio was 1.61:1. The buccal mucosa was the most common site (88.20%). White lichen was seen in 83.59% and red lichen in 16.40% cases. Reticular type of OLP was the most common form (83.5%) followed by erosive (15.6%) and atrophic OLP (0.78%). The incidence of systemic diseases included hypertension (11%), diabetes mellitus (2.4%), and hypothyroidism (0.78%). Histopathologically epithelial dysplasia was present in 4 cases. CONCLUSION: Most of the characteristics are consistent with previous studies with differences in few. Lichen planus is a chronic disease where treatment is directed to control of symptoms. Long-term follow-up is essential to monitor for symptomatic flare ups and possible malignant transformation.

3.
J Oral Maxillofac Pathol ; 17(1): 149, 2013 Jan.
Artigo em Inglês | MEDLINE | ID: mdl-23798857

RESUMO

Ameloblastic fibroma (AF) is a relatively rare, slow growing benign mixed odontogenic tumor, comprising of 1.5-4.5% of all odontogenic tumors. It is usually asymptomatic except for the eventual expansion of the jaw. AFs are most common in adolescents and young adults, mostly affecting the mandible as a well-defined uni or multilocular radiolucency. The effective surgical treatment includes enucleation and curettage of the surrounding bone and removal of the affected teeth. Although recurrence of AF is rare, a long term follow up is recommended. This report describes a 1-year-old girl with AF in the mandible and discusses its clinical, radiographic and histological findings.

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