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1.
J Craniomaxillofac Surg ; 45(6): 981-989, 2017 Jun.
Artigo em Inglês | MEDLINE | ID: mdl-28389105

RESUMO

Posterior calvarial vault osteodistraction (PCVO) has become increasingly popular in the correction of craniosynostosis. When compared to cranioplasty, PCVO offers a shorter, less invasive operation, greater intracranial volume advancement and a lower rate of relapse. In general, distraction protocols are based primarily on clinical observations rather than systematic research. Faster distraction protocols may reduce complications. However, distraction protocols producing higher forces can increase complications. Thus, we need to understand these forces in order to improve distraction protocols and devices. We developed a force measurement method that can be used on PCVO devices. Here, we present preliminary data about the forces developed during PCVO. We measured the forces in four bicoronal craniosynostosis patients during PCVO. We observed a linear-like trend between the force increase and the distraction distance within distraction sessions. We also observed a step-wise force increase between distraction sessions and found that the distraction force relaxed rapidly shortly after the distraction session. The mean maximum pre-distraction force for one distracter was 20.4 N, while the mean maximum end-distraction force for one distracter was 57.6 N. Our data suggests that current treatment protocols might be re-evaluated favouring shorter distraction distances and more frequent distraction sessions.


Assuntos
Craniossinostoses/cirurgia , Osteogênese por Distração/métodos , Craniossinostoses/diagnóstico por imagem , Feminino , Humanos , Imageamento Tridimensional , Lactente , Interpretação de Imagem Radiográfica Assistida por Computador , Estresse Mecânico , Tomografia Computadorizada por Raios X , Torque , Resultado do Tratamento
2.
Am J Transplant ; 11(2): 386-93, 2011 Feb.
Artigo em Inglês | MEDLINE | ID: mdl-21214855

RESUMO

Composite facial allotransplantation is emerging as a treatment option for severe facial disfigurements. The technical feasibility of facial transplantation has been demonstrated, and the initial clinical outcomes have been encouraging. We report an excellent functional and anatomical restoration 1 year after face transplantation. A 59-year-old male with severe disfigurement from electrical burn injury was treated with a facial allograft composed of bone and soft tissues to restore midfacial form and function. An initial potent antirejection treatment was tapered to minimal dose of immunosuppression. There were no surgical complications. The patient demonstrated facial redness during the initial postoperative months. One acute rejection episode was reversed with a brief methylprednisolone bolus treatment. Pathological analysis and the donor's medical history suggested that rosacea transferred from the donor caused the erythema, successfully treated with topical metronidazol. Significant restoration of nasal breathing, speech, feeding, sensation and animation was achieved. The patient was highly satisfied with the esthetic result, and regained much of his capacity for normal social life. Composite facial allotransplantation, along with minimal and well-tolerated immunosuppression, was successfully utilized to restore facial form and function in a patient with severe disfigurement of the midface.


Assuntos
Queimaduras por Corrente Elétrica/cirurgia , Traumatismos Faciais/cirurgia , Transplante de Face/métodos , Queimaduras por Corrente Elétrica/patologia , Traumatismos Faciais/patologia , Transplante de Face/efeitos adversos , Transplante de Face/patologia , Transplante de Face/fisiologia , Rejeição de Enxerto/etiologia , Humanos , Masculino , Pessoa de Meia-Idade , Rosácea/etiologia , Rosácea/patologia
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