Study of microcirculation of the ocular ciliary body in experimental kidney disease.

We studied disorders in ciliary body microcirculation in experimental chronic glomerulonephritis with tubulointerstitial nephritis and evaluated the hemodynamic effects of low-frequency pulsed electromagnetic field in this pathology. Laser Doppler flowmetry demonstrated vasospasm with reduced nutrient blood fl ow in the ciliary body of animals with experimental chronic glomerulonephritis with tubulointerstitial nephritis. The exposure to low-frequency pulsed electromagnetic field using developed technology will lead to significant reduction of the vascular tone and improve arterial blood supply to the microcirculatory bed.

[Characteristics of the autonomic nervous system state in children with myopia associated with undifferentiated connective tissue dysplasia].

Autonomic nervous system disorders occur in 100% cases in patients with connective tissue dysplasia. Biomechanism of accommodation and autonomic innervation of ciliary body was not investigated clearly and presented as area of further research. The goal of the study was to evaluate features of autonomic nervous system in patients with myopia associated with connective tissue dysplasia. 50 children with myopia associated with connective tissue dysplasia went through ophtholmological examination. To evaluate function of autonomic nervous system all patients were observed with the machine "Valenta" which has ECG recording. As a result we found that children with myopia and connective tissue dysplasia have unsatisfactory adaptive reserves with imbalance of sympathetic and parasympathetic input, autonomic nervous system wasn't available to provide homeostasis in demanding level. We hypothesized that autonomic nervous system might be a reason which lead to disorders in process of accommodation during myopia and assist its progressing.

Changes in the retina in induced hypoestrogenia (according to optical coherent tomography data).

Ultrastructural changes in the retina under conditions of experimental hypoestrogenia were studied. Hypoestrogenic status was induced in female rabbits by extirpation of both uterine horns with appendages. Clinical status of the eyes was evaluated after 9 months by ophthalmoscopy and optical coherent tomography. Changes in the retinal layers under conditions of experimental estrogenia were detected: thickened retinal pigmented epithelium layer, a lesser layer of nerve fibrils, and thinning of the choriocapillary layer. A relationship between thinning of the choroid and thickening of the pigmented epithelium of the retina was detected.

[Accommodation examination in myopia associated with nondifferentiated connective tissue dysplasia].

Features of accommodative response in children with myopia associated with nondifferentiated connective tissue dysplasia (NCTD) were studied using computered accommodography. A variety of accommodative response patterns were found in myopia associated with NCTD, that is indicative of a great functional potential of ciliary muscle. Theoretic side is discussed for normal accommodative response and for muscle fibers hyperfunction as well.

[To the treatment of progressive myopia in children].

The paper deals with a new treatment technology for childhood progressive myopia concurrent with chronic diseases. The technology of vision preservation in children of a general educational establishment includes complex phytotherapeutic exposure and infrasound pneumomassage of eyeball tissues. Infrasound ocular pneumomassage at a pressure of 0.1 atm, with a frequency of 4 Hz, and an infrasound power of 170 dB improves muscle accommodation function, blood circulation and lowers intraocular pressure. The developed complex technology contributes to a reduction in the incidence of exacerbations of chronic diseases and exerts a beneficial effect on the course of myopia in children.

[Experience of clinical use infrasound pneumomassage in the treatment of progressive myopia in schoolchildren]. / Opyt klinicheskogo primeneniia infrazvukovogo pnevmomassazha v lechenii progressiruiushcheí blizorukosti u deteí shkol'nogo vozrasta.

Infrasound pneumomassage at a frequency of 4 Hz, duty factor 0.5, and amplitude 0.1 kg/cm, 10-min exposures for 10 days, stabilized the course of progressive myopia, as shown by examinations 3 years after treatment. The most expressed changes were observed in various portions of the vascular membrane.

[Causes of insufficient effectiveness of collagen plasty (an experimental study)]. / O prichinakh nedostatochnoi éffektivnosti kollagenoplastiki (éksperimental'noe issledovanie).

Morphological and biomechanical features of the sclera after collagen plasty were studied in 90 eyes of 45 chinchilla rabbits. A reduction of the viscous elastic properties of the sclera 1 month after surgery was revealed, not described previously. The data on the changed mechanical characteristics of the sclera following collagen plasty are confirmed by the results of optic and electron microscopy; these data permit us to propose that the sclera in the immediate postoperative period (less than 1 month after the operation) represents a somewhat chaotic structure at the stage of active restructuring. Rational postoperative management of patients after collagen plasty is recommended.