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Clin Transl Oncol ; 23(12): 2460-2473, 2021 Dec.
Artigo em Inglês | MEDLINE | ID: mdl-34212338

RESUMO

Rhabdomyosarcoma (RMS) is the most frequent soft tissue sarcoma (STS) in children and adolescents. In Spain the annual incidence is 4.4 cases per million children < 14 years. It is an uncommon neoplasm in adults, but 40% of RMS are diagnosed in patients over 20 years of age, representing 1% of all STS in this age group. RMS can appear anywhere in the body, with some sites more frequently affected including head and neck, genitourinary system and limbs. Assessment of a patient with suspicion of RMS includes imaging studies (MRI, CT, PET-CT) and biopsy. All patients with RMS should receive chemotherapy, either at diagnosis in advanced or metastatic stages, or after initial resection in early local stages. Local control includes surgery and/or radiotherapy depending on site, stage, histology and response to chemotherapy. This guide provides recommendations for diagnosis, staging and treatment of this neoplasm.


Assuntos
Tomografia por Emissão de Pósitrons combinada à Tomografia Computadorizada/métodos , Guias de Prática Clínica como Assunto/normas , Rabdomiossarcoma/terapia , Criança , Terapia Combinada , Humanos , Incidência , Rabdomiossarcoma/diagnóstico por imagem , Rabdomiossarcoma/epidemiologia , Rabdomiossarcoma/patologia , Espanha/epidemiologia
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