RESUMO
Vaccines against Tritrichomonas foetus have been shown to reduce the time of infection after natural or experimental exposure. The object of this study was to assess the protection against T. foetus infection conferred by a single vaginal instillation of formaldehyde fixed T. foetus cells. Aberdeen Angus virgin heifers were randomly allocated to 3 groups of 12 individuals to receive placebo or formaldehyde fixed T. foetus cells prepared following one of two procedures (formalin or freshly prepared solution) and six weeks later they were challenged with 106T. foetus trophozoites. The median time for clearance among control heifers was 93.75 days while in animals immunized with formaldehyde fixed T. foetus it was 45 days. A single vaginal dose of cells fixed with fresh formaldehyde solution gave a rate of decay of infection per unit of time of 2.54 (CI 95%â¯=â¯1.07;6.01).
Assuntos
Subpopulações de Linfócitos B/parasitologia , Doenças dos Bovinos/prevenção & controle , Imunização/veterinária , Infecções Protozoárias em Animais/prevenção & controle , Vacinas Protozoárias/imunologia , Tritrichomonas foetus/imunologia , Administração Intravaginal , Animais , Bovinos , Doenças dos Bovinos/imunologia , Feminino , Formaldeído/química , Infecções Protozoárias em Animais/imunologiaRESUMO
Brucella suis biovar 1 is the causative agent of brucellosis in several domestic and wild animals and it is a common agent of human brucellosis. European hares (Lepus europaeus) have been shown to be infected by B. suis biovar 1 and the transmission to other animals has been suggested. In this work, experimental rabbits (Cuniculus orictolagus) were infected with B. suis biovar 1 isolated from wild hares. Infected rabbits showed high serological response in 2 weeks after discharge and typical granulomatous lesions (2mm diameter) were found in liver, spleen and kidneys after 50 days. B. suis biovar 1 was cultured from the lesion of the organs mentioned above as well as from urine, placenta and fetuses. These data suggest that hares are a potential source for horizontal transmission of B. suis biovar 1 to other mammalians.
Assuntos
Brucella suis/patogenicidade , Brucelose/veterinária , Lebres/microbiologia , Coelhos/microbiologia , Animais , Animais Selvagens/microbiologia , Brucelose/patologia , Feminino , Rim/microbiologia , Rim/patologia , Fígado/microbiologia , Fígado/patologia , Masculino , Gravidez , Complicações Infecciosas na Gravidez/microbiologia , Complicações Infecciosas na Gravidez/veterinária , Baço/microbiologia , Baço/patologiaRESUMO
A fin de determinar el valor de la Angio TC en el diagnóstico de aneurismas intracraneanos se estudiaron 40 pacientes con cuadro clínico de HSA y/o imagen tomográfica compatible con aneurisma intracraneano. Se reconstruyeron las imágenes en el modo 3D de proyección de intensidad máxima (MIP). Treinta y siete de los pacientes fueron estudiados con angiografía por sustracción digital (ASD). En 34 de los 40 pacientes estudiados se realizó diagnóstico positivo de aneurisma intracraneano. Los 6 restantes presentaron Angio TC normal, siendo uno de ellos falso negativo, puesto en evidencia por la ASD. Concluimos que la Angio TC normal es un método rápido, poco invasivo y muy confiable para la detección de aneurismas intracraneanos que puede ser realizado a continuación del diagnóstico tomográfico de SAH, posibilitando así una cirugía de emergencia