Anatomy of the Buccal Space: Surgical and Radiological Perspectives.

Among the anatomical spaces in the head and neck area, the buccal space has often been studied in dental/oral surgery and cosmetic surgery because it contains the facial vessels, mandibular and facial nerves, and adipose tissue called the buccal fat pad. In addition, as the space can communicate with other spaces, it can be significant in infections. Although the anatomy of the buccal space has been reported in several studies, there have been discrepancies concerning its boundaries, and its communications have often been overlooked. The aim of this review is to examine the anatomy of buccal space including its boundaries, contents, continuity with adjacent spaces, and clinical significance. A literature review was performed on Google Scholar and PubMed. The literature has depicted the anterior, medial, and lateral boundaries more or less consistently, but descriptions of the posterior, superior, and inferior borders are controversial. The buccal space includes the facial arteries, veins, facial nerves, parotid duct, and lymph nodes, which can be described differently depending on definitions and the extent of the space. As it communicates with other anatomical spaces including the masticatory space, it can be a reservoir and a channel for infections and tumors. Buccal fat pads have various clinical applications, from a candidate for flap reconstruction to a target for removal for cosmetic purposes. This review will help understand the anatomy of the buccal space including its boundaries, residing structures, and communication with other spaces from surgical and radiological perspectives.

Lymph Node Stations of Pancreas Which Are Identified in Real Color Sectioned Images of a Cadaver With Pancreatic Cancer.

BACKGROUND: In pancreatic cancer surgery, anatomical understanding of lymph node metastases is required. Distinguishing lymph nodes in computed tomography or magnetic resonance imaging is challenging for novice doctors and medical students because of their small size and similar color to surrounding tissues. This study aimed to enhance our understanding of the clinical anatomy of lymph node stations relevant to pancreatic cancer using newly sectioned images of a cadaver with true color and high resolution and their three-dimensional (3D) models. METHODS: An 88-year-old female cadaver who died of pancreatic cancer was serially sectioned. Among the sectioned images of the whole body (0.05 mm-sized pixel, 48 bits color), images of the abdomen were selected, and examined to identify lymph nodes and nearby structures. 34 structures (9 in digestive system; 1 in urinary system; 2 in cardiovascular system; 22 in lymphatic system) were segmented on the sectioned images. Based on the sectioned and segmented images, volume and surface models were produced. RESULTS: Among the known 28 lymph node stations, 21 stations were identified through location, size, and color of normal and abnormal structures in the sectioned images and 3D models. Two near the splenic artery could not be separated from the cancer tissue, and the remaining five were not clearly identified. In the surface models, the shape and location of lymph node stations could be confirmed with nearby structures. CONCLUSION: The lymph node stations relevant to pancreatic cancer can be anatomically understood by using the sectioned images and 3D models which contain true color and high resolution.

Effects of an easy neuroanatomy book with schematics on student learning / Efectos de un libro sencillo de neuroanatomía con esquemas sobre el aprendizaje de los estudiantes

SUMMARY: Numerous students perceive neuroanatomy as a particularly difficult subject due to its overwhelming complexity. Therefore, a neuroanatomy book that concentrates on easy-to-read stories with schematics rather than exhaustive details has been published. This study evaluates the effect of a trial of the new neuroanatomy book on student learning. From the book, a printout on the brainstem and cranial nerve was extracted. Medical students read the printout, and subsequently were examined on their knowledge of and interest in neuroanatomy. Students who read the extract answered examination questions relatively well and were more interested in neuroanatomy. The printout seemed to enhance the knowledge and concentration of the students. After grasping the fundamental information in the book, students are expected to be able to learn advanced concepts comfortably and confidently. In addition, the book with its concise and simple content is suitable not only for short- duration neuroanatomy courses but also for self-learning.

Muchos estudiantes perciben la neuroanatomía como un tema particularmente difícil debido a su abrumadora complejidad. Por lo tanto, se ha publicado un libro de neuroanatomía que se concentra en historias fáciles de leer con esquemas en lugar de detalles exhaustivos. Este estudio evalúa el efecto de una prueba del nuevo libro de neuroanatomía en el aprendizaje de los estudiantes. Del libro, se extrajo una impresión sobre el tronco encefálico y los nervios craneales. Los estudiantes de medicina leyeron la copia impresa y, posteriormente, se les examinó su conocimiento e interés por la neuroanatomía. Los estudiantes que leyeron el extracto respondieron relativamente bien a las preguntas del examen y estaban más interesados en la neuroanatomía. La impresión parecía mejorar el conocimiento y la concentración de los estudiantes. Después de comprender la información fundamental del libro, se espera que los estudiantes puedan aprender conceptos avanzados con comodidad y confianza. Además, el libro con su contenido conciso y simple es adecuado no solo para cursos de neuroanatomía de corta duración, sino también, para el autoaprendizaje.

Darier Disease with Psoriasis.

Darier disease is an autosomal dominant disorder with dark crusty patches and is classified as hereditary acantholytic dermatosis. Keratotic papules and crust are often present on the scalp, forehead, chest, back, upper arms, elbows, groin, and behind the ears, predominantly in seborrheic areas. A 48-year-old male patient presented skin lesions with pruritus on the trunk and both upper and lower extremities. He first noticed the lesion 15 years before. On physical examination, there were multiple erythematous papules with crust on the trunk and red-brown colored keratotic plaque on both extremities. The suspected histopathological diagnosis was psoriasis vulgaris. The patient's skin lesions and pruritus were significantly improved after the psoriasis treatment. While continuing psoriasis treatment, the patient showed sudden worsening of the skin lesions on the scalp, abdomen, and fingernails (V-shaped nicks) with pruritus. Punch biopsy was performed on the abdominal lesion again and the final diagnosis was Darier disease. The patient was then treated using alitretinoin while maintaining the use of guselkumab for psoriasis. There are only a few cases that we found in which patients with Darier disease also had psoriasis. We report this rare case of Darier disease with psoriasis and propose that an additional biopsy might be necessary for accurate diagnosis and proper treatment.

Identification of cranial nerve ganglia using sectioned images and three-dimensional models of a cadaver.

Background: Cranial nerve ganglia, which are prone to viral infections and tumors, are located deep in the head, so their detailed anatomy is difficult to understand using conventional cadaver dissection. For locating the small ganglia in medical images, their sectional anatomy should be learned by medical students and doctors. The purpose of this study is to elucidate cranial ganglia anatomy using sectioned images and three-dimensional (3D) models of a cadaver. Methods: One thousand two hundred and forty-six sectioned images of a male cadaver were examined to identify the cranial nerve ganglia. Using the real color sectioned images, real color volume model having a voxel size of 0.4 × 0.4 × 0.4 mm was produced. Results: The sectioned images and 3D models can be downloaded for free from a webpage, anatomy.dongguk.ac.kr/ganglia. On the images and model, all the cranial nerve ganglia and their whole course were identified. In case of the facial nerve, the geniculate, pterygopalatine, and submandibular ganglia were clearly identified. In case of the glossopharyngeal nerve, the superior, inferior, and otic ganglia were found. Thanks to the high resolution and real color of the sectioned images and volume models, detailed observation of the ganglia was possible. Since the volume models can be cut both in orthogonal planes and oblique planes, advanced sectional anatomy of the ganglia can be explained concretely. Conclusions: The sectioned images and 3D models will be helpful resources for understanding cranial nerve ganglia anatomy, for performing related surgical procedures.

Advanced-sectioned images obtained by microsectioning of the entire male body.

Realistic two-dimensional (2D) and three-dimensional (3D) applications for anatomical studies are being developed from true-colored sectioned images. We generated advanced-sectioned images of the entire male body and verified that anatomical structures of both normal and abnormal shapes could be visualized in them. The cadaver was serially sectioned at constant intervals using a cryomacrotome. The sectioned surfaces were photographed using a digital camera to generate horizontal advanced-sectioned images in which normal and abnormal structures were classified. Advanced-sectioned images of the entire male body were generated. The image resolution was 3.3 × 3.3 fold better than that of the first sectioned images obtained in 2002. In the advanced-sectioned images, normal and abnormal structures ranging from microscopic (≥0.06 mm × 0.06 mm; pixel size) to macroscopic (≤473.1 mm × 202 mm; body size) could be identified. Furthermore, the real shapes and actual sites of lung cancer and lymph node enlargement were ascertained in them. Such images will be useful because of their true color and high resolution in digital 2D and 3D applications for gross anatomy and clinical anatomy. In future, we plan to generate new advanced-sectioned images of abnormal cadavers with different diseases for clinical anatomy studies.

Effects of open board lecture videos on anatomy / Efectos de los videos de conferencias de tablero abierto sobre anatomía

SUMMARY: COVID-19 has forced anatomists to perform non-face-to-face education using lecture videos. A Korean anatomist has given (white and black) board lectures and distributed lecture videos to the public for many years. This study was to verify the effects of open board lecture videos in the anatomy field. A questionnaire survey was carried out with the help of medical students who were exposed to the board lecture videos. The video provider uploaded the lecture videos on YouTube, where the viewing numbers were counted. At a medical school where the video provider belonged, the students mainly watched the lecture videos before the anatomy class. The watching hours of the lecture videos were related to the written examination scores. Students gave positive and negative comments on the board lectures. At the other two medical schools, students partly watched the lecture videos regardless of the teacher who delivered the lectures. The results suggested that students understood the board lectures themselves. On YouTube, the lecture videos were viewed by approximately 1,000 students. This paper introduces the desirable aspects of open board lecture videos on anatomy. The videos could enhance the quality of both students and teacher.

RESUMEN: COVID-19 ha obligado a los anatomistas a realizar una enseñanza no presencial mediante videos de conferencias. Un anatomista coreano ha impartido conferencias (en blanco y negro) y ha distribuido videos de conferencias al público durante muchos años. El objetivo de este estudio fue verificar los efectos de los videos de conferencias de pizarra abierta en el campo de la anatomía. Se llevó a cabo una encuesta con la ayuda de estudiantes de medicina que habían sido expuestos a los videos de conferencias de la pizarra. El proveedor de videos subió los videos de las conferencias a YouTube, donde se contabilizó el número de visualizaciones. En una facultad de medicina a la que pertenecía el proveedor de videos, los estudiantes vieron principalmente los videos de conferencias antes de la clase de anatomía. Las horas de revisión de los vídeos de las conferencias se relacionaron con las puntuaciones de los exámenes escritos. Los estudiantes dieron comentarios positivos y negativos sobre las conferencias de la pizarra. En las otras dos facultades de medicina, los estudiantes vieron parcialmente los videos de las clases, independientemente del profesor que las impartiera. Los resultados sugerían que los estudiantes entendieron las conferencias de la pizarra por sí mismos. En YouTube, los videos de las conferencias fueron vistos por aproximadamente 1000 estudiantes. Este artículo presenta los aspectos deseables de los videos de conferencias abiertas sobre anatomía. Los videos podrían mejorar la calidad tanto de los estudiantes como del profesor.

Movable surface models of hand joints using visible korean / Modelos de superficies móviles de articulaciones de manos utilizando visible Korean

SUMMARY: The human hand can make precise movements utilizing several joints of various articular types. To understand hand movements more accurately, it is essential to view the actual movements of bones and muscles considering the X, Y, and Z axes in the joints. This study aimed to investigate the joint movements in a hand using movable surface models, including these axes. These movable surface models of the hand will improve medical students' understanding of hand movements around the joints. To achieve this aim, 70 surface models were adopted from a Visible Korean model. Using Maya software, 20 virtual joints with X, Y, and Z axes included nine distal and proximal interphalangeal joints, five metacarpophalangeal joints, five carpometacarpal joints, and one wrist joint were created. Bone surface models were elaborately polished to maintain their original shape during movement. Muscle surface models were also processed to display the deformation of the muscle shape during movement. The surface models of the hand joints were moved by virtual control of the joints. We saved 87 movable surface models of the hand, including bones, muscles, and joint axes in stereolithography format, and compiled a Portable Document Format (PDF) file. Using the PDF file, the joint movements in a hand could be observed considering the X, Y, and Z axes alongside the stereoscopic shapes of the bones and muscles. These movable surface models of the hand will improve medical students' understanding of hand movements around the joints.

RESUMEN: La mano humana puede realizar movimientos precisos utilizando varias articulaciones de diferentes tipos articulares. Para comprender los movimientos de las manos con mayor precisión, es esencial ver los movimientos reales de los huesos y los músculos considerando los ejes X, Y y Z de las articulaciones. Este estudio tuvo como objetivo investigar los movimientos articulares en una mano utilizando modelos de superficies móviles, incluidos estos ejes. Estos modelos de superficie móvil de la mano mejorarán la comprensión de los estudiantes de medicina de los movimientos de la mano alrededor de las articulaciones. Para lograr este objetivo, se adoptaron 70 modelos de superficie de un modelo coreano visible. Con el software Maya, se crearon 20 articulaciones virtuales con ejes X, Y y Z que incluyeron nueve articulaciones interfalángicas distales y proximales, cinco articulaciones metacarpofalángicas, cinco articulaciones carpometacarpianas y una articulación de muñeca. Los modelos de superficie ósea se pulieron minuciosamente para mantener su forma original durante el movimiento. También se procesaron modelos de superficie muscular para mostrar la deformación de la forma del músculo durante el movimiento. Los modelos de superficie de las articulaciones de las manos se movieron mediante el control virtual de las articulaciones. Guardamos 87 modelos de superficies móviles de la mano, incluidos huesos, músculos y ejes articulares en formato de estereolitografía, y compilamos un archivo en formato de documento portátil (PDF). Usando el archivo PDF, los movimientos de las articulaciones en una mano se pueden observar considerando los ejes X, Y y Z junto con las formas estereoscópicas de los huesos y músculos. Estos modelos de superficie móvil de la mano mejorarán la comprensión de los estudiantes de medicina sobre los movimientos de la mano alrededor de las articulaciones.

Peeled images and sectioned images from real-color volume models of foot.

PURPOSE: In all educational materials, the foot cannot be peeled from skin to the bone at constant intervals, like as real dissection. The aim of this study was to produce the peeled images which the foot structures can be peeled gradually along a skin-curved surface in real color, like a real dissection. In addition, the sectioned images of typical and atypical planes are presented in real color and high resolution. METHODS: From the sectioned images of real color, foot volume models were made using Photoshop, Matlab, and MRIcroGL. Peeled images and sectioned images of the typical planes were produced from the volume models. All images were placed into the browsing software. An atypical plane could be shown in a real-time using the volume models of the foot. RESULTS: Using the peeled images, in which the foot can be rotated at 5-degree intervals and stripped gradually at 0-30 mm depth, the foot anatomy could be learned precisely and efficiently. The sectional anatomy of the foot for radiology and orthopedic surgery could also be learned easily using the sectioned images of typical (horizontal, coronal, and sagittal) and atypical planes. CONCLUSION: The most significant merit of the volume models is that all outcomes can be displayed with proper colors of the body structures on any plane. By virtue of these merits, the volume models are useful for learning medical education, research, and clinical practice.

2D browsing software and 3D PDF of canine ear based on real color sectioned images / Software de navegación 2D y PDF en 3D del oído canino basado en imágenes seccionadas en color real

Dog ear is very important because of disease vulnerability. Therefore, gross anatomy and sectional anatomy on CT and MRI of the dog ear should be mastered by veterinarian. The purpose of this research was to present the digital atlases which high quality sectioned images and 3D models of detailed structures of dog ear could be displayed freely. In the sectioned images of a female beagle, ear structures were reconstructed by surface modeling to make 3D models. The sectioned images and 3D models were put into the browsing software and PDF file, respectively. Using the browsing software and the PDF file, gross and radiological anatomy of dog ear could be learned easily and accurately. The auditory tube of a dog was placed anterior to the tympanic cavity unlike human. The tensor tympani muscle of a dog was connected to the dorsal wall of the tympanic cavity with the malleus. No remarkable difference in the auditory ossicles, semicircular ducts, facial nerve, and endolymphatic duct was observed between dogs and humans. The software and the PDF file will be provided to other researchers freely to help contribute to veterinary research and education.

La oreja del perro es importante debido a la vulnerabilidad de enfermedad. Por lo tanto, el veterinario debe conocer plenamente la anatomía macroscópica y la anatomía seccional en la TC y la RM del oído del perro. El objetivo de esta investigación fue presentar los atlas digitales que podían mostrar imágenes seccionadas de alta calidad y modelos 3D de estructuras detalladas de orejas de perro. En las imágenes seccionadas de una hembra Beagle, las estructuras de las orejas se reconstruyeron mediante modelado de superficie con el objetivo de crear modelos 3D. Las imágenes seccionadas y los modelos 3D se colocaron en un software de navegación y un archivo PDF. El uso de software de navegación y el archivo PDF permiten un aprendizaje fácil y preciso de la anatomía macroscópica y radiológica de la oreja de perro. El músculo tensor del tímpano de un perro estaba conectado a la pared dorsal de la cavidad timpánica con el martillo. No se observaron diferencias notables en los huesecillos auditivos, los conductos semicirculares, el nervio facial y el conducto endolinfático entre perros y humanos. El software y el archivo PDF estarán disponibles libremente para los investigadores para ayudar en la investigación y educación veterinaria.

Neuroman: Voxel Phantoms from Surface Models of 300 Head Structures Including 12 Pairs of Cranial Nerves.

For a precise simulation of electromagnetic radiation effects, voxel phantoms require detailed structures to approximate humans. The phantoms currently used still do not have sophisticated structures. This paper presents voxel and surface models of 300 head structures with cranial nerves and reports on a technique for voxel reconstruction of the cranial nerves having very thin and small structures. In real-color sectioned images of the head (voxel size: 0.1 mm), 300 structures were segmented using Photoshop. A surface reconstruction was performed automatically on Mimics. Voxel conversion was run on Voxel Studio. The abnormal shapes of the voxel models were found and classified into three types: thin cord, thin layers, and thin parts in the structures. The abnormal voxel models were amended using extended, filled, and manual voxelization methods devised for this study. Surface models in STL format and as PDF files of the 300 head structures were produced. The STL format has good scalability, so it can be used in most three-dimensional surface model software. The PDF file is very user friendly for students and researchers who want to learn the head anatomy. Voxel models of 300 head structures were produced (TXT format), and their voxel quantity and weight were measured. A voxel model is difficult to handle, and the surface model cannot use the radiation simulation. Consequently, the best method for making precise phantoms is one in which the flaws of the voxel and surface models complement each other, as in the present study.

Development of a nonhuman primate computational phantom for radiation dosimetry.

PURPOSE: The nonhuman primate (NHP) is an important animal model for evaluating the response of the human body to radiation exposure owing to similarities between its organ structure, genome, life span, and metabolism. However, there is a lack of radiation dosimetry estimations for NHPs. The aim of this work is to construct a computational phantom of NHPs and estimate absorbed fractions and specific absorbed fractions for internal radiation dosimetry. MATERIALS AND METHODS: A female rhesus monkey was frozen and sectioned using a cryomacrotome. The transaxial sectioned images were imported into Adobe Photoshop for segmentation of internal organs. A total of 31 organs/tissues were identified and labeled. The segmented voxel phantom was then converted to a boundary representation (BREP) phantom to enable easy alteration of the phantom to mimic monkeys of different stature. The BREP model was then voxelized and imported into the MCNPX Monte Carlo radiation transport code for electron and photon dosimetry calculations. To estimate the appropriateness of using human phantoms as surrogate models for NHPs, absorbed fractions (AFs) and specific absorbed fractions (SAFs) of monoenergetic electrons and photons were calculated and compared with the ICRP reference newborn female phantom and a 1-yr-old female phantom. RESULTS: Considerable differences were observed for both self-absorbed and cross-absorbed doses for some organs between the NHP phantom and newborn phantom. For example, the ratios of the self-absorbed SAF(stomach wall) Monkey to SAF(stomach wall) Newborn ranged from 0.06 at 10 keV to 0.29 at 3 MeV for photons while the corresponding ratios to cross-absorbed SAF(liver→kidney) Monkey to SAF(liver→kidney) Newborn ranged from 0.78 at 50 keV to 5.78 at 10 keV for photons. Conversely, values of self-absorbed SAF were much higher (ratios of 2.39-4.19) for the brain and much lower for the uterus (0.51-0.61) in the monkey model compared to the newborn phantom. These dose differences can be attributed to the disparities between organ masses, shapes, and positions between the two phantoms. CONCLUSIONS: The developed NHP model can be exploited for the assessment of radiation dose to NHPs in preclinical radiation dosimetry studies and radiation therapy research.

True-color face peeled images with botulinum toxin injection sites and anatomic landmarks / Imágenes de color verdadero de rostros sin piel con puntos de inyección de toxina botulínica y puntos de referencia anatómicos

To allow students and surgeons to learn the sites for botulinum toxin injection, new types of educational images are needed because MRI, CT, and sectioned images are inadequate. This article describes browsing software that displays face peeled images that allow layers along the curved surface of the face to be peeled gradually in even depths across the surface. Two volume models of the head were reconstructed from sectioned images and segmented images of Visible Korean, respectively. These volume models were peeled serially at a thickness of 0.2 mm along the curved surface of the facial skin to construct the peeled images and peeled segmented images. All of the peeled images were marked with botulinum toxin injection sites, facial creases and wrinkles, and fat compartments. All peeled images and the text information were entered into browsing software. The browsing software shows 12 botulinum toxin injection sites on all peeled images of the anterior and lateral views. Further, the software shows 23 anatomic landmarks, 13 facial creases and wrinkles, and 7 face fat compartments. When a user points at any structure on the peeled images, the name of the structure appears. Our software featuring the peeled images will be particularly effective for helping medical students to quickly and easily learn the accurate facial anatomy for botulinum toxin injection sites. It will also be useful for explaining plastic surgery procedures to patients and studying the anatomic structure of the human face.

Para permitir que los estudiantes y cirujanos aprendan los sitios para la inyección de toxina botulínica, se necesitan nuevos tipos de imágenes educativas ya que las imágenes de MRI, CT e imágenes seccionadas son inadecuadas. Este artículo describe el software de navegación que muestra imágenes de cara sin piel que permiten que las capas a lo largo de la superficie curva de la cara se despeguen gradualmente en profundidades uniformes a lo largo de la superficie. Se reconstruyeron dos modelos de volumen de la cabeza a partir de imágenes seccionadas e imágenes segmentadas visibles, respectivamente. En estos modelos de volumen se retiró la piel en serie con un grosor de 0,2 mm a lo largo de la superficie curva de la cara para construir las imágenes sin piel y las imágenes segmentadas sin piel. Todas las imágenes sin piel se marcaron con puntos de inyección de toxina botulínica, arrugas y arrugas faciales y compartimientos de grasa. Todas las imágenes despegadas y la información de texto se ingresaron en el software de navegación. El software de navegación muestra 12 sitios de inyección de toxina botulínica en todas las imágenes de las vistas anterior y lateral. Además, el software muestra 23 puntos de referencia anatómicos, 13 pliegues y arrugas faciales y 7 compartimentos de grasa facial. Cuando un usuario selecciona cualquier estructura en las imágenes sin piel, aparece el nombre de la estructura. Nuestro software con las imágenes sin piel será particularmente efectivo para ayudar a los estudiantes de medicina a aprender rápida y fácilmente la anatomía facial precisa para los sitios de inyección de toxina botulínica. También será útil para explicar los procedimientos de cirugía plástica a pacientes y estudiar la estructura anatómica del rostro humano.

Automatic 3D modeling of liver segments including segmental branches of portal triad and hepatic vein based on the sectioned-images / Modelado 3D automático de segmentos hepáticos, con las ramas segmentarias de la tríada portal y la vena hepática basadas en las imágenes seccionadas

SUMMARY: The liver dimensional (3D) models, consists of eight segments including portal triad (portal vein, hepatic artery, and bile duct), are necessary because it is difficult to dissect a liver and its inner structures. But it is difficult to produce 3D models from high resolution and color sectioned-images. This study presents automatic and accurate methods for producing liver 3D models from the sectionedimages. Based on the sectioned-images and color-filled-images of the liver, a 3D model including both the portal triad and hepatic vein was made. Referring to the 3D model, 3D models of liver's eight segments including the segmental branches of the portal triad and hepatic vein were completed and saved as STL format. All STL files were combined and saved as Liver-3D in PDF format for the common user. By functional subdivision of liver, the Liver-3D was divided into left (segments II, III, and, IV) and right (segments V, VI, VII, and VIII) liver in bookmark window of the PDF file. In addition, in Liver-3D, the primary to tertiary segmental branches of the portal triad could be shown in different colors. Owing to the difficulty of 3D modeling of liver including eight segments and segmental branches of the portal triad and hepatic, we started this research to find automatic methods for producing 3D models. The methods for producing liver 3D models will assist in 2D selection and 3D modeling of other complicated structures.

RESUMEN: Los modelos hepáticos dimensionales (3D) consisten en ocho segmentos que incluyen la tríada portal (vena porta, arteria hepática y conducto biliar), y son necesarios ya que es difícil disecar un hígado y sus estructuras internas. Sin embargo, es difícil producir modelos 3D a partir de imágenes en alta resolución e imágenes seccionadas en color. Este estudio presenta métodos automáticos y precisos para producir modelos 3D de hígado a partir de las imágenes seccionadas. Sobre la base de las imágenes seccionadas y las imágenes del hígado llenas de color, se realizó un modelo 3D que incluía tanto la tríada portal como la vena hepática. En referencia al modelo 3D, se completaron modelos 3D de los ocho segmentos del hígado que incluían las ramas segmentarias de la tríada portal y la vena hepática y se guardaron como formato STL. Todos los archivos STL fueron combinados y guardados como Liver-3D en formato PDF para el usuario común. Por subdivisión funcional del hígado, el hígado-3D se dividió en hígado izquierdo (segmentos II, III y IV) y derecho (segmentos V, VI, VII y VIII) en la ventana de marcador del archivo PDF. Además, en Liver-3D, las ramas segmentarias primarias a terciarias de la tríada portal podrían mostrarse en diferentes colores. Debido a la dificultad del modelado 3D del hígado, incluidos ocho segmentos y ramas segmentarias de la tríada portal y hepática, comenzamos esta investigación para encontrar métodos automáticos para producir modelos 3D. Los métodos para producir modelos 3D de hígado ayudarán en la selección 2D y el modelado 3D de otras estructuras complicadas.

Sectioned images of a cat head to contribute to learning of its sectional anatomy / Imágenes seccionadas de una cabeza de gato para contribuir al conocimiento de su anatomía seccional

The sectional anatomy of a cat head is essential when interpreting CTs and MRIs of the region. In learning the sectional anatomy, sectioned images of a cat could be quite effective data. The main objective was to assist veterinary physicians who learn the sectional anatomy of a cat head by presenting high-quality sectioned images. A short-haired female cat was frozen and sectioned frontally using a cryomacrotome. Every sectioned surface in real body color was photographed with a digital camera. The frontal planes were stacked to produce dorsal and sagittal planes. High-quality sectioned images of a cat head allowed the identification of small, complicated structures. The notable structures were as follows: each bone of the cranium, structures of the brain, tympanic cavity (larger than human), oval window (larger than human), vestibular nerve, cochlear nerve, ear ossicles, six extraocular muscles, pupil (larger than human), retractor bulbi muscle (not found in human), optic nerve, olfactory bulb (considerably large), vomeronasal organ duct (not found in human), infraorbital gland (not found in human), masticatory muscles (larger than human), maxillary nerve (larger than human), and mandibular nerve. This pacesetting report describes the detailed head structures of a cat from the viewpoint of sectional anatomy. The sectioned images will be given to other interested researchers free of charge.

El conocimiento de la anatomía seccional de cabeza de gato es esencial para interpretar estudios por tomografía computada y resonancia magnética de la región. En el conocimiento de esta anatomía seccional, las imágenes seccionadas de un gato podrían aportar datos bastante efectivos. El objetivo principal consistió en ayudar a los médicos veterinarios para que aprendan la anatomía seccional de una cabeza de gato mediante la presentación de imágenes seccionadas de alta calidad. Una gata de pelo corto fue congelada y seccionada frontalmente usando un criomicrótomo. Cada sección, con el color real del cuerpo, fue fotografiada con una cámara digital. Los planos frontales se apilaron para producir planos dorsales y sagitales. Las imágenes seccionadas de alta calidad de una cabeza de gato permitieron la identificación de estructuras pequeñas y de dificil visualización. Las estructuras destacadas fueron las siguientes: cada hueso del cráneo, las estructuras del cerebro, la cavidad timpánica (más grande que en el humano), la ventana oval (más grande que en el humano), el nervio vestibular, el nervio coclear, los huesecillos del oído, seis músculos extraoculares, la pupila, el músculo retractor del ojo (no se encuentra en el ser humano), nervio óptico, bulbo olfatorio (considerablemente grande), conducto del órgano vomeronasal (no se encuentra en el ser humano), glándula infraorbitaria (no se encuentra en los humanos), músculos masticatorios (más grandes que en el humano), nervio maxilar (más grande que en el humano) y nervio mandibular. En este trabajo describimos detalladamente, desde el punto de vista de la anatomía seccional, las estructuras de la cabeza de un gato. Las imágenes seccionadas estarán a disponibles para otros investigadores en forma gratuita.

Browsing software of the head sectioned images for the android mobile device / Software de navegación para el dispositivo móvil android de imágenes seccionadas de cabeza

SUMMARY: The purpose of this research was to enable anyone to learn the sectional anatomy of the head anywhere, anytime by presenting software to browse sectioned images on a Google Android mobile device. Among the 2,343 sectioned images at 0.1 mm intervals, 234 sectioned images at 1 mm intervals were chosen. The corresponding 234 segmented images containing 236 head structures were selected. The software of the mobile version was programmed and debugged in the Java programming language. The folders of the sectioned images and segmented images and the txt file of the segmentation data were arranged in the source code of the software. The software was distributed free of charge at the homepage (neuroanatomy.kr) and Google Play Store. After installing the software, the sectioned images and corresponding segmented images could be browsed by touching and swiping the screen. In the medical category of the Google Play Store, the software earned a good reputation. The software of the Android mobile version was usable regardless of the time and place. The software is under the authors' non-commercial policy. Other investigators may modify the mobile software to browse their own images. The mobile version of the software will aid medical students and doctors in learning sectional anatomy.

RESUMEN: El propósito de esta investigación fue permitir que toda persona aprendiera la anatomía de secciones de la cabeza, en cualquier lugar y en cualquier momento, a través de un software para examinar imágenes seccionadas en un dispositivo móvil Android de Google. De las 2.343 imágenes seccionadas a intervalos de 0,1 mm, se seleccionaron 234 imágenes seccionadas a intervalos de 1 mm. Se seleccionaron las 234 imágenes segmentadas que contenían 236 estructuras de cabeza. El software de la versión móvil fue programado y depurado en el lenguaje de programación Java. Las carpetas de las imágenes seccionadas y las imágenes segmentadas y el archivo .txt de los datos de segmentación se organizaron en el código fuente del software. El software se distribuyó gratuitamente en la página principal (neuroanatomy.kr) y Google Play Store. Después de instalar el software, las imágenes seccionadas y las imágenes segmentadas correspondientes se pueden navegar tocando y deslizando la pantalla. En la categoría médica de Google Play Store, el software obtuvo buena recepción. El software de la versión móvil de Android fue utilizado independientemente de la hora y el lugar. El software está bajo la política no comercial de los autores. Otros investigadores pueden modificar el software móvil para navegar por sus propias imágenes. La versión móvil del software ayudará a los estudiantes de medicina y los médicos en el aprendizaje de la anatomía seccional.

Ten Triangles around Cavernous Sinus for Surgical Approach, Described by Schematic Diagram and Three Dimensional Models with the Sectioned Images.

For the surgical approach to lesions around the cavernous sinus (CS), triangular spaces around CS have been devised. However, educational materials for learning the triangles were insufficient. The purpose of this study is to present educational materials about the triangles, consisting of a schematic diagram and 3-dimensional (3D) models with sectioned images. To achieve the purposes, other studies were analyzed to establish new definitions and names of the triangular spaces. Learning materials including schematic diagrams and 3D models with cadaver's sectioned images were manufactured. Our new definition was attested by observing the sectioned images and 3D models. The triangles and the four representative surgical approaches were stereoscopically indicated on the 3D models. All materials of this study were put into Portable Document Format file and were distributed freely at our homepage (anatomy.dongguk.ac.kr/triangles). By using our schematic diagram and the 3D models with sectioned images, ten triangles and the related structures could be understood and observed accurately. We expect that our data will contribute to anatomy education, surgery training, and radiologic understanding of the triangles and related structures.

Anomalous branching patterns of the axillary artery / Patrones de ramificación anómalos de la arteria axilar

Arterial variations in the upper limbs can cause iatrogenic injury during invasive procedures. During educational dissection of countered uncommon branching patterns of the axillary artery which have not yet been reported yet, to our knowledge. First, the second part of the axillary artery was divided into three trunks. The lateral trunk ran downward as a superficial brachioradial artery. The medial trunk raised the lateral thoracic artery, and was divided into the subscapular artery and the posterior circumflex humeral artery. The intermediate trunk branched off the anterior circumflex humeral artery as expected for an axillary artery. Second, in the other cadaver, we found a common trunk containing the thoracoacromial artery and a bulk artery dividing into three branches, the subscapular, posterior circumflex humeral, and lateral thoracic arteries. Taken together, we discuss the clinical implications and possible developmental origins of variations in the axillary artery branching and course.

Las variaciones arteriales en los miembros superiores pueden causar lesiones iatrogénicas al realizarse procedimientos invasivos. Durante una disección de rutina de los patrones de ramificación de la arteria axilar, se encontró una disposición aún no informada. En primer lugar, la segunda porción de la arteria axilar se presentó dividida en tres troncos. El tronco lateral se desplazó hacia abajo como una arteria braquiorradial superficial (arteria radial originándose de la arteria axilar). El tronco medial dio origen a la arteria torácica lateral, y se dividió en arteria subescapular y arteria circunfleja humeral posterior. El tronco intermedio dio origen a la arteria circunfleja humeral anterior como se espera para una arteria axilar. En un segundo cadáver, encontramos un tronco común entre la arteria toracoacromial y una arteria de mayor tamaño que se dividió en tres arterias: subescapular, circunfleja humeral posterior y torácica lateral. Consideradas estas variaciones arteriales en conjunto, se discuten las implicaciones clínicas y posibles orígenes del desarrollo de las variaciones en la ramificación de la arteria axilar y su trayecto.

Improved Sectioned Images and Surface Models of the Whole Female Body / Mejoramiento de Imágenes Seccionadas y Modelos de Superficie del Cuerpo Femenino Completo

The objective of this research was to present high-quality sectioned images of a whole female body which would be helpful in creating an atlas, virtual dissection, and various applications for medical education and clinical trial. In addition, the authors sought to demonstrate the applicabilities of sectioned images. A female cadaver was ground serially using the cryomacrotome and photographed to make the sectioned images. Structures in the images were segmented to produce segmented images in Photoshop. In the self-developed browsing software, the sectioned and segmented images were stored. Based on the segmented images, surface models were built on commercial software and saved as PDF file. High-quality sectioned images of the female body were taken (intervals, 0.2 mm or 1 mm; pixel size, 0.1 mm; color depth, 48 bit color). In the images obtained, very small and complicated structures could be identified in color of living body. In order to ascertain the applicability of the images, the browsing software including sectioned and segmented images and the PDF file including surface models were produced. The sectioned images and surface models produced during this research will prove to be a useful source for medical software. All data generated is available free of charge.

El objetivo fue presentar imágenes seccionadas en alta calidad de un cuerpo femenino que sería de gran ayuda en la creación de un atlas, en la disección virtual y en diversas aplicaciones para la educación médica y los ensayos clínicos; además, se trata de demostrar la aplicabilidad de las imágenes seccionadas. Un cadáver de sexo femenino fue seccionado en serie utilizando un criomicrótomo y luego fue fotografiado. Las estructuras en las imágenes fueron segmentadas para producir imágenes en Photoshop. En un programa de navegación de desarrollo propio se almacenaron las imágenes seccionadas y segmentadas. Basado en las imágenes segmentadas, los modelos de superficie fueron construidas en el programa y guardadas como archivo PDF. Las imágenes seccionadas de alta calidad del cuerpo femenino fueron tomadas con intervalos entre 0,2 o 1 mm; tamaño en píxeles de 0,1 mm y profundidad de color de 48 bits). En las imágenes obtenidas, las estructuras muy pequeñas y complicadas pudieron ser identificadas a color en el cuerpo. Con el fin de determinar la aplicabilidad de las imágenes, se produjo un programa de navegación que incluye imágenes seccionadas y segmentadas y el archivo PDF que incluye modelos de superficie. Las imágenes seccionadas y los modelos de superficie producidos durante esta investigación demostraron ser una fuente útil como programa médico. Todos los datos generados se encuentran disponibles gratuitamente.