[Multiple lentigines syndrome or leopard syndrome. Presentation of a clinical case]. / La sindrome della lentigginosi multipla o sindrome "leopard". Presentazione di un caso clinico.

Multiple lentigenes syndrome is a complex genetic dermatosis with dominant autosomal transmission an varying degrees of penetration first described in 1969. Apart from disseminated lentigenes at least two of the following are present: cardiac and neurosensory alterations, cervicofacial genitourinary and endocrinological dysmorphias, retarded growth and other skin conditions. MLS has also been called LEOPARD syndrome (Gorlin et al. 1969), thus being an acronym that memorizes the various anomalies involved: L = lentigines, E = ECG anomalies, O = ocular hypertelorism, P = pulmonary stenosis, A = anomalies of the genital organs, R = retarded growth, D = deafness. The clinical and diagnostic aspects of MLS are critically analysed and the case of a woman with the syndrome admitted to San Camillo Hospital, Rome is examined.

[Primary intestinal lymphomas. Review of the literature apropos of a clinical case]. / I linfomi primitivi intestinali. Rassegna della letteratura a proposito di un caso clinico.

A rare case of primary lymphoma of the bowel in a 26 year old woman is reported and the complex problems of diagnosis and treatment are examined. The importance of establishing the primary or secondary nature of this tumour of the small bowel is emphasised. This is because primary intestinal tumours require the most radical treatment possible even in advanced stages of the disease in order to avoid complications and to identify the areas involved in the proliferative process. Finally the importance of continuing surgery with drug and radiation treatment in order to improve prognosis is emphasised.