1.
Arq. biol. tecnol
; 40(2): 405-11, jun.1997. graf
Artigo
em Inglês
| LILACS
| ID: lil-240745
RESUMO
The present work aims to optimize the complex medium for the production of actinomycin-D by S.parvulus. The quantitative influence of the medium components was investigated in order to maximize the antibiotic synthesis. In the original medium, concentrations of actinomycin-D not higher than 245 ug/ml were achieved. In contrast, with the optimized medium the antibiotic concentration reached a value of approximately 530 ug/ml