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1.
Pharmacology ; 87(1-2): 28-35, 2011.
Artigo em Inglês | MEDLINE | ID: mdl-21178387

RESUMO

INTRODUCTION: In order to definitively integrate cryosurgery for the surgical treatment of atrial fibrillation (AF) into the therapeutic armamentarium, the medical and economic impact of its use on a population of patients with a high risk of recurrence of postoperative AF must be evaluated. METHOD: An observational study of patients who benefited from cryosurgery between July 2006 and December 2008 was performed. The cost of consumables and hospitalization was determined and compared to that of a control group of 27 patients with preoperative AF that had not benefited from cryosurgery. RESULTS: Twenty-nine patients benefited from cryosurgery during a mitral (65.5%) or aortic intervention (37.9%) to treat a paroxystic (44.8%) or permanent AF (55.2%). More than half of them (58.6%) had a 12-month follow-up; 82.4% of these patients showed a permanent sinus rhythm and 32.6% had stopped their antiarrhythmic medication. There was no significant difference between the duration and cost of hospitalization for the 2 groups. CONCLUSION: Cryosurgery provides a clear clinical and economic advantage with no recurrence of AF, and it reduces antiarrhythmic medication treatment.


Assuntos
Fibrilação Atrial/economia , Fibrilação Atrial/cirurgia , Criocirurgia/efeitos adversos , Criocirurgia/economia , Custos de Cuidados de Saúde , Adulto , Idoso , Idoso de 80 Anos ou mais , Antiarrítmicos/uso terapêutico , Fibrilação Atrial/complicações , Procedimentos Cirúrgicos Cardíacos , Feminino , França , Cardiopatias/complicações , Cardiopatias/cirurgia , Hospitais Universitários , Humanos , Tempo de Internação , Masculino , Prontuários Médicos , Pessoa de Meia-Idade , Estudos Retrospectivos , Prevenção Secundária , Avaliação da Tecnologia Biomédica , Resultado do Tratamento
2.
Therapie ; 63(5): 377-83, 2008.
Artigo em Francês | MEDLINE | ID: mdl-19154707

RESUMO

INTRODUCTION: The impact of the use of biological and synthetic glues in cardiac surgery was assessed by an economic and medical study. MATERIAL AND METHODS: The observational prospective study had duration of three months. All the patients undergoing cardiac surgery were included in the study. The end points were medical (blood transfusion) and economic (duration and cost of the stay in hospital). There were 2 groups: treated or not by glues. STATISTICAL ANALYSIS: T Student tests. RESULTS: Among 154 patients, the 2 principal indications were valvular replacement (48%) and coronary artery bypass grafting (37%). Fifty seven (37%) patients received a glue. The number of transfused globular units and the duration of the stay in the intensive care unit were significantly higher (p<0.05) by treated patients. CONCLUSION: Not only the use of glues did not decrease the post-operative bleedings but it increased also the cost of the stay in hospital. Guidelines were validated by the hospital Commission on drugs.


Assuntos
Adesivos/economia , Adesivos/uso terapêutico , Procedimentos Cirúrgicos Cardíacos/economia , Procedimentos Cirúrgicos Cardíacos/métodos , Hemostasia/fisiologia , Adulto , Idoso , Idoso de 80 Anos ou mais , Fibrinogênio/economia , Fibrinogênio/uso terapêutico , França , Glutaral/economia , Glutaral/uso terapêutico , Humanos , Tempo de Internação/economia , Pessoa de Meia-Idade , Estudos Prospectivos , Proteínas/economia , Proteínas/uso terapêutico , Amido/economia , Amido/uso terapêutico
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