1.
Australas J Dermatol
; 63(3): e270-e273, 2022 08.
Artigo
em Inglês
| MEDLINE
| ID: mdl-35674390
2.
Indian J Dermatol
; 64(3): 231-234, 2019.
Artigo
em Inglês
| MEDLINE
| ID: mdl-31148863
RESUMO
Acanthosis nigricans (AN) describes clinically hyperpigmented skin, which most commonly affects the flexural areas such as axilla, groin and neck. It is usually a benign condition associated with obesity, insulin resistance, and hyperinsulinemia; endocrinopathy; or malignancy, in particular, gastrointestinal adenocarcinoma. It can also occur in association with various genetic syndromes involving various organ systems. Few such known syndromes are Berardinelli-Seip syndrome, Alström syndrome, Leprechaunism, and Bardet-Biedl syndrome. MORFAN syndrome, which associates mild mental retardation, pre- and post-natal overgrowth, remarkable facies and diffuse and widespread AN, is a rare entity.