Chemical annotation of small and peptide-like molecules at the Protein Data Bank.

Over the past decade, the number of polymers and their complexes with small molecules in the Protein Data Bank archive (PDB) has continued to increase significantly. To support scientific advancements and ensure the best quality and completeness of the data files over the next 10 years and beyond, the Worldwide PDB partnership that manages the PDB archive is developing a new deposition and annotation system. This system focuses on efficient data capture across all supported experimental methods. The new deposition and annotation system is composed of four major modules that together support all of the processing requirements for a PDB entry. In this article, we describe one such module called the Chemical Component Annotation Tool. This tool uses information from both the Chemical Component Dictionary and Biologically Interesting molecule Reference Dictionary to aid in annotation. Benchmark studies have shown that the Chemical Component Annotation Tool provides significant improvements in processing efficiency and data quality. Database URL: http://wwpdb.org.

Madre acompañante en terapia intensiva: tensiones psicológicas / The accompanyn mother at the intensive care unit: psychological stress

Se destaca que el ingreso de un niño en terapia intensiva es una situación de tensión psicológica. Se estudia mediante un cuestionario cómo las madres prefieren permanecer junto a su hijo, pues se sienten más seguras, con más esperanzas, mejor informadas, los lactan, alimentan, cambian de ropa y apoyan emocionalmente. Se da a conocer la importancia de que la madre sea atendida e informada por el pediatra, así como el esfuerzo conjunto de todos